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1 sequence enriched in positively charged and aromatic amino acids.
2 and contained multiple large hydrophobic and aromatic amino acids.
3 norepinephrine and for the hydroxylation of aromatic amino acids.
4 ritical branch point in the synthesis of the aromatic amino acids.
5 B. hydrogenotrophica targets aliphatic and aromatic amino acids.
6 ands of promoters through a conserved set of aromatic amino acids.
7 binds peptides that have a high fraction of aromatic amino acids.
8 tCM shows that *MtCM is not regulated by the aromatic amino acids.
9 is the substitution of this residue with non-aromatic amino acids.
10 ight- and branched-aliphatic amino acids and aromatic amino acids.
11 attributed to overlapping pi-pi orbitals of aromatic amino acids.
12 in the visible range even in the absence of aromatic amino acids.
13 ributed to overlapping pi-pi orbitals of key aromatic amino acids.
14 rt assays show that PhpCAT exports all three aromatic amino acids.
15 in the Acanthamoeba spp. that synthesize the aromatic amino acids.
16 spiratory nitrogen cycle and accumulation of aromatic amino acids.
17 of the Tyr9 residue with different unnatural aromatic amino acids.
20 ating branched-chain amino acids (BCAAs) and aromatic amino acids (AAAs) have been shown to be associ
21 Based on recent studies, fluorophores-mainly aromatic amino acids (AAAs) in proteins-might be respons
22 ch as branched-chain amino acids (BCAAs) and aromatic amino acids (AAAs), have been associated with d
25 ptome identified a phylogenetically distinct aromatic amino acid aminotransferase (ArAT), designated
28 n the antioxidant activity as well as on the aromatic amino acid and carotenoid contents in ordinary
30 ge with particular carbon sources, including aromatic amino acids and acyclic terpenes, suggesting a
31 In conclusion, the levels of branched-chain, aromatic amino acids and alanine increased and the level
32 resonance energy transfer between PPAR alpha aromatic amino acids and bound corresponding naturally o
33 that Pal is a versatile surrogate to natural aromatic amino acids and can be employed as an alternati
35 in) using commercially available fluorinated aromatic amino acids and fluorinated precursors as examp
36 viously reported markers, branched-chain and aromatic amino acids and glutamine/glutamate, were assoc
37 llular bacterium that is auxotrophic for the aromatic amino acids and histidine, causes scrub typhus,
39 s drawn into biosynthetic pathways that form aromatic amino acids and other important metabolites, in
40 In some cases, the PTM domain is rich in aromatic amino acids and plays an important role in memb
43 d to determine the structures of the neutral aromatic amino acids and their complexes to Na(+) and K(
44 ectron capture mass spectra of aliphatic and aromatic amino acids and their methyl esters show intens
47 lasses and particle size, branched-chain and aromatic amino acids, and inflammation-related glycoprot
48 the role of a surface-accessible cluster of aromatic amino acids, and purified mutant proteins were
49 dia but do not grow in defined media lacking aromatic amino acids, and the growth defect is rescued b
50 rostatic and conformational perturbations of aromatic amino acids are associated with metal cluster a
53 phate (DKFP) pathway for the biosynthesis of aromatic amino acids (AroAAs) and p-aminobenzoic acid (P
55 ence, with a net positive charge and several aromatic amino acids, as a putative membrane-interacting
57 lectivity for N-protected dipeptides with an aromatic amino acid at the carboxylic terminus, which pr
59 aled strong evidence that branched-chain and aromatic amino acids (BCAAs and AAAs) are closely associ
60 d intracellular levels of branched-chain and aromatic amino acids (BCAAs and ARO AAs, respectively) a
61 ays for H2O2 resistance included DNA repair, aromatic amino acid biosynthesis (aroBK), Fe-S cluster b
62 nt set of genes coding for shikimic acid and aromatic amino acid biosynthesis enzymes, leading to the
63 se-1-phosphate (DKFP), a precursor sugar for aromatic amino acid biosynthesis in Methanocaldococcus j
64 at allows complex control of the pathway for aromatic amino acid biosynthesis in the pathogen Mycobac
65 s that B. thailandensis, when exposed to the aromatic amino acid biosynthesis inhibitor glyphosate, i
66 We also used our module to control flux into aromatic amino acid biosynthesis to increase titers of s
68 olite in the established shikimic pathway of aromatic amino acid biosynthesis, are absent in most eur
69 M. tuberculosis provide exquisite control of aromatic amino acid biosynthesis, not only controlling f
73 ers (except C(3)) in this unusual tetrahydro-aromatic amino acid building block, giving insights into
74 nits (phhA, hpd, hmgA, and dhcA) involved in aromatic amino acid catabolism; however, genes involved
77 olate high-affinity oligonucleotides against aromatic amino acids complexed in situ with a nonspecifi
79 synthesis, tryptophan hydroxylase (TPH) and aromatic amino acid decarboxylase (AADC) are expressed i
80 synthesizes dopamine through the actions of aromatic amino acid decarboxylase (AADC) in the proximal
83 mainly attributed to its decarboxylation by aromatic amino acid decarboxylase (AADC), an enzyme over
86 The cell death was reversed by caspases and aromatic amino acid decarboxylase and monoamine oxidase
87 s metabolized by the concerted action of the aromatic amino acid decarboxylase and monoamine oxidase.
89 ro-l-m-tyrosine ([(18)F]FMT; a substrate for aromatic amino acid decarboxylase), baseline D2/3 recept
90 thesis enzymes tyrosine hydroxylase (TH) and aromatic amino acid decarboxylase, providing a novel mec
94 e Catharanthus roseus and Papaver somniferum aromatic amino acid decarboxylases changes the enzymes d
96 MAGE (CoS-MAGE) to optimize biosynthesis of aromatic amino acid derivatives by combinatorially inser
97 -12-independent Th1 differentiation, whereas aromatic amino acid-derived AHR ligands were selectively
100 dy it has been shown how incorporation of an aromatic amino acid drastically improves selective antib
102 protein (IFABP) by incorporating fluorinated aromatic amino acids during synthesis in Escherichia col
103 and charging of tRNAs for branched chain and aromatic amino acids (e.g. leucine and tryptophan), the
104 res, conformation of disulphide bridges, and aromatic amino acid environment, depended on the fibres
105 y matrix of key intrinsic fluorophores, like aromatic amino acids, enzyme cofactors, and vitamins.
106 ikimate pathway leads to the biosynthesis of aromatic amino acids essential for protein biosynthesis
107 nd receptor signaling, (ii) substitutions of aromatic amino acids F295 and F296 in TM6 with alanine a
108 yrosine decarboxylase (TDC), a member of the aromatic amino acid family, but this enzyme has not been
109 ith a corresponding decrease in the usage of aromatic amino acids, favoring formation of IDR structur
110 d by mutating it to other hydrophobic and/or aromatic amino acids, followed by voltage-clamp experime
111 ritical for assembly, the substitution of an aromatic amino acid for D111 produced a lethal phenotype
115 VLDL-triglycerides, VLDL-diameter, branched/aromatic amino acids, glycoprotein acetyls, and triglyce
116 rrelated with loss of pi-pi stacking between aromatic amino acids H84 and Y83, which removes a wall s
119 by which plants maintain intercompartmental aromatic amino acid homeostasis, and provide critical in
120 biopterin (BH(4)), an essential cofactor for aromatic amino acid hydrolases including tyrosine hydrox
121 ccessful knockout and complementation of the aromatic amino acid hydroxylase AAH2 gene, with no obser
122 e wild type hTPH2, like other members of the aromatic amino acid hydroxylase superfamily, exists as a
123 ) is a pterin-dependent mononuclear non-heme aromatic amino acid hydroxylase that catalyzes the conve
124 dely distributed among eukaryotes, including aromatic amino acid hydroxylases (AAAHs), nitric oxide s
127 erall, these results are consistent with the aromatic amino acid hydroxylases all sharing the same ch
128 Additionally, expression levels of the two aromatic amino acid hydroxylases were negligible both in
133 e, Orf13 is novel in its ability to catalyze aromatic amino acid hydroxylation with hydrogen peroxide
137 erefore asserts a recognition preference for aromatic amino acids in a variety of sequence configurat
138 ore provide a rationale for the abundance of aromatic amino acids in fibril-forming peptides and esta
140 e synthase, a key enzyme in the synthesis of aromatic amino acids in plants, fungi, and bacteria.
141 lution imaging reveals an unexpected role of aromatic amino acids in promoting protein-mHtt aggregate
142 C 7002, through site-directed mutagenesis of aromatic amino acids in the binding niche of the chlorop
150 me 10% of predicted prenylated proteins have aromatic amino acids in their Ca(1)a(2)X sequence and wo
151 The basis of the low PPII propensities of aromatic amino acids in this context was significant cis
152 and enzyme catalysis, and the involvement of aromatic amino acids in this process is of much interest
155 onBs appear to form a single cluster of 8-10 aromatic amino acids, including those found at opposite
159 he change in His-heme loop stability for the aromatic amino acids is caused by a slowdown in the rate
160 w reaction observed between radicals a-c and aromatic amino acids is the addition of the radical to t
161 t enzyme that catalyzes the hydroxylation of aromatic amino acid l-phenylalanine (L-Phe) to l-tyrosin
162 der Caryophyllales, are synthesized from the aromatic amino acid l-tyrosine (Tyr) and replaced the ot
163 IE) by altering extracellular [Ca(2+)] or by aromatic amino acid, L-phenylalanine (L-Phe, endogenous
164 e first two steps in the biosynthesis of the aromatic amino acids leading to 3-dehydroquinate (DHQ).
165 ientation, is sequestered within a basic and aromatic amino acid-lined cleft between the La and RRM1
166 carbon metabolism, pigment biosynthesis and aromatic amino acid metabolism, were significantly modif
170 ontains a large amount of a toxic nonprotein aromatic amino acid, mimosine, and also an enzyme, mimos
171 to binding energy are heavily biased toward aromatic amino acids near the center of the binding surf
173 us most closely related to SARS-CoV, employs aromatic amino acid-nucleobase stacking interactions wit
174 ition, but the site has moved to a different aromatic amino acid of the agonist-binding site dependin
178 etion of a 21-amino acid segment enriched in aromatic amino acids on the C-terminal side of Cys-739 a
179 lementation of infected hMDMs with the three aromatic amino acids or with Trp alone rescues the intra
180 icant stabilization of residual structure by aromatic amino acids, particularly Trp and Phe, and mini
181 pplied this framework to the analysis of the aromatic amino acid pathways and discovered almost 75,00
184 d applications for cyclized analogues of the aromatic amino acids Phe, Tyr, Trp, and His within pepti
186 of COX-2 is also aided by partitioning of 4 aromatic amino acids, Phe(59), Phe(66), Tyr(76), and Phe
187 the temporal and spatial interchange of the aromatic amino acid phenylalanine (Phe) between human re
188 rimental effects of hyperaccumulation of the aromatic amino acid phenylalanine (Phe) in animals, know
191 e first steps of hydration of the protonated aromatic amino acids phenylalanine, tryptophan, and tyro
193 in stark contrast to the general belief that aromatic amino acids play a prominent role in multidrug
194 D-amino acids include N-methyl amino acids, aromatic amino acids, polar amino acids, and hydrophobic
196 hrough a defined pathway involving conserved aromatic amino acids (R2: Y122, W48, Y356; R1: Y731, Y73
197 initiation involves a pathway of transient, aromatic amino acid radical intermediates, including Y73
198 tic determinant of branched-chain amino acid/aromatic amino acid ratio on changes in body weight and
199 he C allele of the branched-chain amino acid/aromatic amino acid ratio-associated variant rs1440581 m
200 We genotyped the branched-chain amino acid/aromatic amino acid ratio-associated variant rs1440581 n
201 ers another level of complexity in the plant aromatic amino acid regulatory network, unveiling new ta
202 udies also revealed that viperin requires an aromatic amino acid residue at its C terminus for proper
204 revealed that the introduction of the large aromatic amino acid residue tryptophan at position 940 p
205 ns near-UV CD signals from its complement of aromatic amino acid residues (one Trp, eight Tyr, and 13
206 ia long-range radical transport (RT) through aromatic amino acid residues (Y122 left arrow over right
207 detected the partial solvent exposure of Pet aromatic amino acid residues at 37 degrees C, and a cell
208 In particular, the relative positioning of aromatic amino acid residues at positions 100 and 107 de
209 hat different cations affected structures of aromatic amino acid residues differently, which indicate
211 se mutations revealed functionally important aromatic amino acid residues in four locations: at the i
213 ing with ASLV(C) glycoproteins, at least two aromatic amino acid residues in the IgV domain of Tvc, T
214 thologues exhibited exclusive preference for aromatic amino acid residues in the P2 position, and for
215 ite-directed mutagenesis of highly conserved aromatic amino acid residues in the SPATE family resulte
216 and replacing Phe(6) and Trp(8) with bulkier aromatic amino acid residues is very important for selec
217 is interface identified two highly conserved aromatic amino acid residues located in the H-I loop and
219 mine oxidases A and B (MAO A and MAO B) show aromatic amino acid residues oriented approximately perp
220 lly possess an "aromatic box," where several aromatic amino acid residues surround the bound ligand.
221 oring bands (particularly those derived from aromatic amino acid residues) as well as the relatively
222 ion by UVR8 is based on intrinsic tryptophan aromatic amino acid residues, with tryptophan-285 as the
224 e present study investigates the role of the aromatic amino acid-responsive regulator PhhR in mediati
226 er, these results, along with the lack of an aromatic amino acid-rich region in CdtC similar to that
227 The juxtamembrane domain (JMD) of S is an aromatic amino acid-rich region proximal to the transmem
228 nscriptional activation of genes involved in aromatic amino acid, S-adenosyl methionine (SAM) and fol
232 1)H enrichment of a single ortho position of aromatic amino acid side chains in an otherwise perdeute
233 n protein-stabilizing interactions involving aromatic amino acid side chains make significant contrib
235 associated benzene rings (a simple model of aromatic amino acid side chains) can switch inherent dyn
237 consists of a deep cleft, heavily lined with aromatic amino acid side-chains but bounded by numerous
239 elative concentrations of branched-chain and aromatic amino acids significantly increased in the free
242 roxylase catalyze the hydroxylation of their aromatic amino acid substrates using a tetrahydropterin
246 changes in Raman vibrations corresponding to aromatic amino acids such as phenylalanine and tryptopha
247 ion of the aromatic residue with a different aromatic amino acid, such as W653Y or Y1302W, did not af
249 beta-sheet areas are rich in cysteine and aromatic amino acids, such as phenylalanine and tyrosine
250 gation in mutated pili that were missing key aromatic amino acids, suggest that the pili of G. sulfur
251 etes, such as branched chain amino acids and aromatic amino acids, suggesting they report on a distin
253 m tumefaciens, and two experimental systems, aromatic amino acid synthesis and DNA transfer in bacter
254 emphasized the genetics and biochemistry of aromatic amino acid synthesis and the characterization o
255 H), a shikimate pathway enzyme essential for aromatic amino acid synthesis, is also required for GA p
256 veal the existence of a fourth, more distant aromatic amino acid that serves as a terminal electron d
257 el provides insight into the organization of aromatic amino acids that are important for electrical c
258 tions were generated for the six C-terminal, aromatic amino acids that mediate most coat-internal sca
260 ist binding sites have the same core of five aromatic amino acids, the fetal site has approximately 3
264 mide intermediate was stabilized by adjacent aromatic amino acids through ring-ring stacking interact
265 r the transmembrane segment using charged or aromatic amino acids, thus limiting the peptides' abilit
266 itionally, exchange of the respective fourth aromatic amino acid to redox-inactive phenylalanines sti
267 nvolving the obligatory binding of essential aromatic amino acids to Mec1, followed by an enhancement
268 on caused by the affinity of hydrophobic and aromatic amino acids toward these surfaces leads to elec
269 lar 3-nitrotyrosine is transported via the l-aromatic amino acid transporter in nondopaminergic NT2 c
270 e addition of aspartate and expression of an aromatic amino acid transporter, as well as a tyrosine-s
274 en quantum yields generated by excited state aromatic amino acids (tryptophan, tyrosine, phenylalanin
276 urthermore, replacing Trp-248 with a smaller aromatic amino acid (Tyr/Phe) impaired the beta-arrestin
278 esis was used to assess the contributions of aromatic amino acids (tyrosine and phenylalanine) to rec
280 15 A distant from the chromophore by another aromatic amino acid, W389F, restores native Pr --> Pfr p
281 no-acid (aa) PTM domain of AcMNPV GP64 lacks aromatic amino acids, we asked whether this region might
283 show that only substitutions of Tyr(511) to aromatic amino acids were able to mimic, albeit partiall
284 more, [Ca(2+)](i) oscillations stimulated by aromatic amino acids were also abolished by inhibition o
285 stream open reading frames encoding multiple aromatic amino acids were found 5' of the translation in
286 Circulating branched-chain amino acids and aromatic amino acids were recently related to insulin re
287 t the [Ca(2+)](i) oscillations stimulated by aromatic amino acids were selectively abolished by TRPC1
288 ng the aroA gene (necessary for synthesizing aromatic amino acids) were able to establish GI coloniza
290 ar capsules based on oligoamide sequences of aromatic amino acids which are capable of binding tartar
291 growth defect is rescued by inclusion of the aromatic amino acids, which are essential for production
292 dified Dulbecco's medium, a medium richer in aromatic amino acids, which give rise to AhR agonists, c
294 cs suggest multiple stacking arrangements of aromatic amino acids with the nucleobases at the junctio
295 ds to extracellular Ca(2+) ([Ca(2+)](o)) and aromatic amino acids with the production of different pa
296 illations that integrates its stimulation by aromatic amino acids with TRPC1 regulation by PKC and ca
297 sponds to two different agonists, Ca(2+) and aromatic amino acids, with the production of sinusoidal
298 s work from our laboratory demonstrated that aromatic amino acids within CF lung secretions (sputum)
299 acid replacements involving arginine and/or aromatic amino acids within the final five C-terminal re
300 posed to involve a hopping mechanism through aromatic amino acids (Y(122) --> W(48) --> Y(356) in bet
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