ライフサイエンスコーパス: array CGH

1 ray-based comparative genomic hybridization (array CGH).

2 ray-based comparative genomic hybridization (array CGH).

3 ough implementation of microarray-based CGH (array CGH).

4 ray-based comparative genomic hybridization (array CGH).

5 by array-comparative genomic hybridization (array CGH).

6 We describe here our implementation of array CGH.

7 ested by chromosome 21 deletions detected by array CGH.

8 DNA isolation and subsequent performance of array CGH.

9 copy number variant that was not detected by array CGH.

10 chromosome 17q21.3, detected in each case by array CGH.

11 woman diagnosed with WHS in her thirties by array-CGH.

12 nomic copy number changes by high-resolution array-CGH.

13 number measurements by MAPH/REDVR, MLPA and array-CGH.

14 lines under analysis were compared with BAC array CGH; 77% (n = 44) of the autosomal chromosomes use

15 idization and single nucleotide polymorphism arrays (CGH-A; SNP-A) can be used for analysis of somati

16 to amplify frozen and FFPE tissue for use in array CGH (aCGH).

17 Array CGH analysis of six paired pre- and post-neoadjuva

18 Cytogenetic and array CGH analysis of TOSE cells also revealed a focal g

19 Array CGH analysis was used to detect a recurrent deleti

20 ome amplification and genomic alterations by array CGH analysis, indicating that Aurora-A overexpress

21 Using array CGH analysis, we have identified six overlapping m

22 Array-CGH analysis identified REST as a frequent target

23 n conditional random field, a new integrated array-CGH analysis method for jointly classifying tumors

24 erated melanoma formation after UV exposure, array-CGH analysis was effective in distinguishing pheno

25 lls, which do not provide sufficient DNA for array-CGH analysis.

26 icroarray comparative genomic hybridization (array CGH) analysis of DNA copy number variation in a se

27 analysed, all eleven imbalances detected by array CGH and confirmed by FISH or Q-PCR were also detec

28 By integrating array CGH and expression array data, we reveal genes who

29 with unbalanced insertions identified using array CGH and FISH in 4909 cases referred to our laborat

30 in 4909 cases referred to our laboratory for array CGH and found to have copy-number abnormalities.

31 These results show the power of combined array CGH and SAGE analysis for the identification of ca

32 f amplicons, we developed a method combining array CGH and serial analysis of gene expression (SAGE)

33 this resource routinely for high-throughput array CGH and single-locus probe analysis of a range of

34 from tumor biopsies, which was coupled with array CGH and targeted resequencing.

35 an be serially transplanted and according to array CGH and whole exome sequencing, the pathogenesis o

36 e combination of next generation sequencing, array-CGH and fluorescence in situ hybridization technol

37 ooked because they may be missed by FISH and array-CGH and may be interpreted as insertions by paired

38 ray-based comparative genomic hybridization (array CGH) and spectral karyotype (SKY) analysis, none o

39 ray-based comparative genomic hybridization (array-CGH) and detected significant DNA copy number chan

40 Using homozygosity mapping, array CGH, and exome sequencing, we uncovered bi-allelic

41 ain and loss were defined more accurately by array CGH, and several small regions of deletion were de

42 ts are the first to establish the utility of array-CGH as a means of etiology-based tumor classificat

43 om designed 4-Mb tiling-path oligonucleotide array CGH assay.

44 ist the use of higher-resolution genome-wide array CGH assays for clinical purposes.

45 ion array-comparative genomic hybridization (array-CGH) assays were performed comparing the subject g

46 dy to combine the modalities of zoo-FISH and array CGH between different avian species.

47 as a distinctive gene expression profile; 2) array CGH can be applied successfully to frozen or forma

48 normal human cells and genomic profiling by array-CGH (cDNA arrays, 100 kb resolution) and by real-t

49 he analysis of the genome, as exemplified by array-CGH (Comparative Genomic Hybridization), scanning

50 lly, the accumulation and annotation of such array CGH data can lead to the rapid identification of p

51 We also present the analyses of array CGH data from breast cancer cell lines to show the

52 The visualization and summarization of the array CGH data outputs, potentially across many samples,

53 integrative analysis of gene expression and array CGH data revealed DNA copy number alterations at t

54 a subset of the calls that differed from the array CGH data sets.

55 Clonality analysis of array CGH data suggested that multiple CRC primary tumor

56 cal and experimental exploration of a set of array CGH data, including both synthetic data and real d

57 methods to identify aberration regions from array CGH data, many recent research work focus on both

58 -ARRAY) for detecting copy-number changes in array CGH data.

59 cable to both next-generation sequencing and array CGH data.

60 t wavelet transform based approach to smooth array CGH data.

61 rinkage estimator respectively to smooth the array CGH data.

62 ompare 11 different algorithms for analyzing array CGH data.

63 Our array-CGH data also shows an XY-homologous region close

64 reconstructing common ancestral genomes via array-CGH data analysis and by comparing representative

65 Developing effective methods for analyzing array-CGH data to detect chromosomal aberrations is very

66 g the accuracy of an algorithm for analyzing array-CGH data, it is commonly assumed that noise in the

67 thods have been proposed for the analysis of array-CGH data.

68 lic array comparative genomic hybridization (array CGH) data, we show that the REPA/B structure is al

69 s have been proposed for analyzing the large array CGH datasets, the relative merits of these methods

70 Three published array-CGH datasets are used to demonstrate our approach.

71 Array-CGH detected 6p22.3 amplification in 8/91 invasive

72 ion of genomic copy number variants (CNV) in array CGH experiments compared to the state-of-the-art,

73 pplied our method to both simulated data and array-CGH experiments on glioblastoma and adenocarcinoma

74 Array-CGH findings revealed predicted duplications in af

75 ve CT method) were performed to validate the array-CGH findings.

76 CNV-seq offers an alternative to array CGH for copy number analysis with resolution and f

77 However, attempts to harness array-CGH for single-cell analysis to provide improved r

78 in-embedded samples of DFSP were analyzed by array CGH (four cases) and DNA microarray analysis of gl

79 ing array comparative genomic hybridization (array CGH), gene expression arrays, and fluorescence in

80 ray-based comparative genomic hybridization (array CGH) has improved rates of detection of chromosoma

81 ray-based comparative genomic hybridization (array-CGH) has emerged as a technique allowing high-thro

82 n identified between chicken and turkey; and array CGH identified 16 inter-specific CNVs.

83 Array CGH identified gain at 8q24.12-q24.13, the region

84 Moreover, classification by array-CGH identified key CNAs unique to each class, incl

85 Overall, array-CGH identified relatively small genomic regions as

86 nd review some of the recent applications of array CGH in cancer and medical genetics.

87 These results indicate that array CGH is a powerful technique to study rearrangement

88 Array-CGH is a powerful tool for the detection of chromo

89 A fundamental question is whether noise in array-CGH is indeed Gaussian, and if not, can one exploi

90 ray-based comparative genomic hybridization (array CGH) is a highly efficient technique, allowing the

91 ray-based comparative genomic hybridization (array CGH) is a powerful new technology capable of ident

92 nome hybridization (CGH) to DNA microarrays (array CGH) is a technique capable of detecting deletions

93 ray-based comparative genomic hybridization (array-CGH) is a popular technology for determining this.

94 ighly amplified regions in MCF-7 detected by array CGH located in the 1p13.1-p21.1, 3p14.1-p14.2, 17q

95 Array CGH may help distinguish between these 2 entities

96 ing array comparative genomic hybridization (array CGH), measuring copy-number gains and losses among

97 Published array CGH methods have relied on large genomic clone (fo

98 Array comparative genome hybridization (array-CGH) methods provide high-throughput data on genet

99 Array CGH of DNA extracted either from frozen tumor samp

100 ray-based comparative genomic hybridization (array CGH) on 64 prostate tumor specimens, including 55

101 med array comparative genomic hybridization (array-CGH) on specimens from 64 patients with newly diag

102 were successfully amplified and screened via array-CGH or Taqman PCR that displayed retention of the

103 ve genomic hybridization to DNA microarrays (array CGH) overcomes these limitations by allowing effic

104 The array CGH panel included 90 animals from 11 Bos taurus,

105 assessment obtained using an oligonucleotide array CGH platform designed to query CNVs at high resolu

106 ion array comparative genomic hybridization (array CGH) platform.

107 and future costs comparable to conventional array CGH platforms and with less stringent sample requi

108 reover, genomic profiling of these tumors by array CGH pointed to regions of loss on chromosomes 6 an

109 s a number of popular algorithms to a single array CGH profile entered by the user.

110 ing array comparative genomic hybridization (array CGH), quantitative PCR (qPCR), and fluorescent in

111 ), fluorescent in-situ hybridization (FISH), array-CGH, quantitative microsatellite analysis (QUMA),

112 the results were comparable with those from array CGH, regions of those genetic changes were defined

113 ermine whether copy-number gains detected by array CGH represent tandem duplications or unbalanced in

114 Drawing relevant conclusions from array-CGH requires computational methods for partitionin

115 All array CGH results agree with the deletion sizes and loca

116 Array CGH revealed complex rearrangements in eight patie

117 ybridization using whole-genome microarrays (array CGH) revealed variation in 24 to 67 genes in isola

118 For murine tumors, array CGH should provide even greater advantage, since m

119 (MSB) procedures; it considers the observed array-CGH signal as sampling from a probability-density

120 earrangements by FISH with BACs and fosmids, array CGH, Southern-blot hybridization, MLPA, RT-PCR, an

121 However, array CGH studies of the human genome noting false negat

122 well-suited to high resolution whole genome array CGH studies that use array probes derived from lar

123 Array CGH technologies enable the simultaneous measureme

124 oftware tool for SV analysis using data from array CGH technologies, which is also amenable to short-

125 xisting methods for detecting aberrations in array-CGH than the Gaussian noise case.

126 By high-resolution tiling array CGH, the smallest common deletion targeted just on

127 This study is the first to use array CGH to characterize IPMNs.

128 We used array CGH to create the first map of DNA copy number var

129 Application of array CGH to tumor specimens makes genetic diagnosis of

130 sed array comparative genomic hybridization (array CGH) to define minimum common amplified regions an

131 ion array comparative genomic hybridization (array CGH) to map the minimal amplified regions.

132 population of loci showing amplification by array-CGH was enriched for palindromes detected by GAPF

133 BAC array comparative genomic hybridization (array CGH) was employed to test DNA from 93 individuals

134 Using array CGH, we further narrowed the loci for LOH9 and LOH

135 By using whole-genome oligonucleotide array CGH, we have identified deletions at 13q32.1 segre

136 Using FISH, linear amplification, and array CGH, we identified a 126-kb duplicated region from

137 By custom array-CGH, we further investigated this family and repor

138 Using high-resolution array-CGH, we identified unique duplications of a region

139 Exome sequencing and array CGH were performed on available samples followed b

140 Newer technology, such as array-CGH, when combined with cDNA microarrays and tissu

141 ed behavior among genomic loci suggests that array CGH will be increasingly important in understandin

142 We anticipate that array CGH will change the diagnostic approach to many co

143 some abnormality, we coupled high-resolution array CGH with breakpoint junction sequencing of a diver

144 Comparison of array CGH with existing multiplex-fluorescence in situ h

145 ray-based comparative genomic hybridisation (array-CGH) with male and female Duroc genomic DNA on a p