ライフサイエンスコーパス: arsenal

1 istance that has emerged to the current drug arsenal.

2 added to the tobacco prevention and control arsenal.

3 ction of viral therapeutics to its medicinal arsenal.

4 proteins in T. gondii's host cell-modifying arsenal.

5 ical agents have been added to the treatment arsenal.

6 ded a primary weapon in the medical research arsenal.

7 s will decide their place in the therapeutic arsenal.

8 active oxygen species is a key part of their arsenal.

9 oming an important weapon in our therapeutic arsenal.

10 erved to foster the role of NO in the immune arsenal.

11 ideal application for SBRT in the treatment arsenal.

12 and highly predictive tool in the chemist's arsenal.

13 s have become part of the approved treatment arsenal.

14 ailable bond disconnections in the synthetic arsenal.

15 growing threat to the utility of our current arsenal.

16 loping future improvements in our antifungal arsenal.

17 this critical gap in the synthetic chemist's arsenal.

18 found a place in the routine cancer-fighting arsenal.

19 their preeminently elaborate photoreceptive arsenal.

20 g means for enhancing our current antibiotic arsenal.

21 o evade the effects of the oncologist's drug arsenal.

22 m that enhance the immunologist's analytical arsenal.

23 ally telesurgery) a standard tool in the MIS arsenal.

24 ding insects include in their antihemostatic arsenal a potent thrombin inhibitor, the flexible and cy

25 as emerged as a promising alternative in the arsenal against cancer by harnessing the power of the im

26 Radionuclide therapy remains a promising arsenal against cancer.

27 pathway is a powerful tool in the host cell arsenal against cytosolic pathogens.

28 new antibacterial drugs is evident, and the arsenal against infectious diseases needs to be improved

29 signaling are essential constituents of the arsenal against MCMV infections, validated the forward g

30 al anti-inflammatory use will strengthen our arsenal against ocular surface disease.

31 l need to improve the tools available in our arsenal against this disease, both in terms of treatment

32 but recent work suggests that this antiviral arsenal also includes the cellular DNA damage response m

33 : specific effectors of the direct antiviral arsenal and host factors that indirectly dampened the ov

34 ause PI-9 can protect CTL from its own fatal arsenal and potentially enhance the vitality of CTL, we

35 The limited therapeutic arsenal and the increase in reports of fungal resistance

36 Hiroshima and the status of today's nuclear arsenals and dangers.

37 e recent literature on the status of nuclear arsenals and the risk of nuclear war.

38 ovel strategies for enhancing our antibiotic arsenal are needed.

39 antibodies occupy an increasing niche in the arsenal available to treat cancer.

40 Although PMNs possess a potent antimicrobial arsenal comprising both oxidative and non-oxidative kill

41 e therapeutic efficacies of our current drug arsenal could be significantly improved with an active d

42 quefaciens does not reflect the vast genetic arsenal devoted to the formation of such compounds.

43 ved from the antitubercular chemotherapeutic arsenal due to toxic side effects.

44 are an important component of the molecular arsenal employed by hosts against bacteria.

45 an important component of the antiapoptosis arsenal encoded by the E3 transcription unit of subgroup

46 ivery pathway and provided evidence that its arsenal extends beyond known effector proteins.

47 or each stress and elucidated a new response arsenal for adapting to radical environments.

48 dified Metarhizium spp represent a major new arsenal for combating insect pests and insect-borne dise

49 l arm surgeons with a powerful and versatile arsenal for intraoperative NIR imaging in real time.

50 s (EBMT) are a new addition to the treatment arsenal for obesity.

51 in the expansion of the current antimalarial arsenal for the elimination of this disease.

52 ensive programmes that deliver an integrated arsenal for tuberculosis control might continue to strug

53 s emerged as a novel tool in our therapeutic arsenals for fighting cancer.

54 it is unknown to what extent the diverse Ig arsenal generated by somatic recombination and diversifi

55 This arsenal has been expanded by the recent discovery of the

56 This arsenal has been studied most extensively in neutrophils

57 tic resistance and formidable immune evasion arsenal have emphasized the need for more effective anti

58 heterogeneity reflects the parasite invasion arsenal in the field.

59 rrently, clinicians have a limited treatment arsenal in the repair of peri-implant defects.

60 A component of this arsenal is a set of proteins, termed restriction factors

61 Our current antibacterial arsenal is composed of growth-inhibiting agents that tar

62 drug development; as a result the antifungal arsenal is exceedingly limited.

63 0 warheads that remain in superpower-nuclear arsenals, many still on hair-trigger alert.

64 DS constitutes a unique tool in the software arsenal now available to evolutionary biologists.

65 The results expand our arsenal of AC inhibitors, thereby facilitating the use o

66 We anticipate that Perseus's arsenal of algorithms and its intuitive usability will e

67 l also enable bench biologists to perform an arsenal of analysis using cutting-edge methods in a fami

68 nd therefore is an important addition to the arsenal of analytical techniques used in carbohydrate re

69 ed UGMDR offers an important addition to the arsenal of analytical tools for identifying nonlinear mu

70 sm-based rationale to the use of our current arsenal of anti-cancer drugs.

71 t PIN1 inhibitors are still missing from the arsenal of anti-cancer drugs.

72 a novel and adaptable method for building an arsenal of antibacterials potentially capable of targeti

73 r decades medicinal chemists replenished the arsenal of antibiotics by semisynthetic and to a lesser

74 sistant bacteria compounded by the depleting arsenal of antibiotics has accelerated efforts toward de

75 Today's arsenal of antibiotics is ineffective against some emerg

76 tuents will be an invaluable addition to the arsenal of anticancer therapeutics.

77 at AMN could be an important addition to our arsenal of antifungals for the treatment of invasive fun

78 Among the host's arsenal of antimicrobial factors, the type 1 interferons

79 Bacteria exploit an arsenal of antimicrobial peptides and proteins to compet

80 l pathogens for which we have a very limited arsenal of antiviral agents.

81 us promises to be a valuable addition to the arsenal of approaches for tackling the NMR sampling prob

82 A new arsenal of approaches, including single-molecule fluores

83 eported herein is a new entry in the growing arsenal of arylmethyl ether protecting groups.

84 ET will be a valuable addition to the narrow arsenal of automatic gene prediction tools.

85 Although the arsenal of bacterial effectors and their cellular target

86 s and efflux pumps, along with an increasing arsenal of beta-lactamases.

87 Evolution has provided ticks with an arsenal of bioactive saliva molecules that counteract ho

88 At the time of this writing, the arsenal of biophysical methods for such measurements is

89 ave become one of the primary weapons in the arsenal of biophysicists, and have revolutionized the ne

90 tical need to expand our currently available arsenal of broad-spectrum antibiotics.

91 f new potential targets will ensure that the arsenal of cancer therapies continues to expand.

92 t-activated catalysts in conjunction with an arsenal of carbon-radical precursors, an array of triflu

93 Compared with the enormous arsenal of catalysts used to produce organic compounds,

94 In the current arsenal of catalytic dihalogenation technologies, the di

95 are equivalent to portions of the regulatory arsenal of Ci.

96 can be recovered and the availability of an arsenal of classical and emerging methods for manipulati

97 hy has become a major diagnostic tool in the arsenal of clinical cardiology for real-time imaging of

98 d by the experimental methodologies from the arsenal of combinatorial chemistry.

99 taphylococcus aureus possesses an impressive arsenal of complement evasion proteins that help the bac

100 t AR signaling and resistance to the current arsenal of conventional and next generation AR-directed

101 These novel nanoparticles may extend the arsenal of currently available nanoparticle MR contrast

102 oster cancer development despite wielding an arsenal of cytotoxic agents.

103 striction-modification module, expanding the arsenal of defence systems known to be at the disposal o

104 s activated and olive massively releases the arsenal of defense.

105 o combat these invaders, bacteria possess an arsenal of defenses, such as CRISPR-Cas adaptive immunit

106 Poison frogs have a diverse arsenal of defensive alkaloids that target the nervous s

107 of sedentary phytonematodes suggests that an arsenal of different secreted parasitism proteins from t

108 ver the decades, what we have in our current arsenal of drugs for this potentially devastating diseas

109 This resistance limits the arsenal of effective antimicrobials available for infect

110 Despite an increasing arsenal of effective treatments, there are mounting chal

111 t with the host cell, it delivers a distinct arsenal of effector proteins directly into the cytoplasm

112 An arsenal of effector proteins is injected by bacterial pa

113 etes infect their hosts, they employ a large arsenal of effector proteins to establish a successful i

114 The reported arsenal of effectors is likely to expand since genomic a

115 and cell types due, in part, to the diverse arsenal of effectors it secretes into the host cell.

116 ever-growing threat because of the shrinking arsenal of efficacious antibiotics.

117 Cells possess an arsenal of enzymatic tools capable of remodeling and rep

118 ned beetle genome encodes a uniquely diverse arsenal of enzymes that can degrade the main polysacchar

119 ibitors, which could complement the existing arsenal of epigenetic drugs that are currently limited t

120 At the same time, an expanding arsenal of experimental tools can constrain models and d

121 pathogen Ustilago maydis encodes a different arsenal of extracellular hydrolases with more copies of

122 M. globosa shares a similar arsenal of extracellular hydrolases with the phylogeneti

123 To expand the arsenal of fluorescent cytidine analogues for the detect

124 ters encoding different proteins with a vast arsenal of functions, including carbohydrate binding, tr

125 eby filling an important void in the current arsenal of gene-therapy vectors.

126 A wider arsenal of genes related to oxidative stress, cellular r

127 with reduced cost have led to unraveling the arsenal of genes utilized by the colonic Bacteroidetes t

128 e model species Drosophila, which has a rich arsenal of genetic tools.

129 o the availability of a large and increasing arsenal of genetically modified mouse strains and molecu

130 This greatly extends the arsenal of graphene materials and their potential for a

131 asive S. aureus strains secrete an extensive arsenal of hemolysins, immunomodulators, and exoenzymes

132 he overall reaction sequence complements the arsenal of Horner-Wadsworth-Emmons-type coupling reactio

133 ges in nutrient availability and to evade an arsenal of host defenses.

134 This exploits the full arsenal of imaging statistics to discover and replicate

135 coccus aureus expresses a highly diversified arsenal of immune evasion proteins, many of which target

136 another mechanism to the already formidable arsenal of immunoevasion tactics used by solid tumors.

137 The established arsenal of immunomodulatory proteins encoded by viruses

138 osyltransferase is a valuable addition to an arsenal of immunoreactive proteins which could be incorp

139 machinery, which is probably composed of an arsenal of intracellular, CED-3-like cysteine proteases.

140 y different phyla have evolved an impressive arsenal of light manipulation strategies that rely on th

141 changing the TCR affinity will allow a large arsenal of low-avidity T cells previously thought to be

142 to be tested in conjunction with the growing arsenal of markers for human plasmacytoid dendritic cell

143 D4(+) T-cell functions that indicate a large arsenal of mechanisms by which CD4(+) T cells act to com

144 Living organisms use a sophisticated arsenal of membrane receptors, channels, and pumps to co

145 addressed by tapping into the ever expanding arsenal of methods to manipulate ions in the gas phase o

146 y become a valuable addition to the existing arsenal of methods used to monitor duplex DNA interactio

147 d through direct observation using the large arsenal of molecular tools available for Arabidopsis.

148 ged as an important weapon in the pathogenic arsenal of multiple intracellular protozoan parasites.

149 Together, our study provides an arsenal of multivalent immunogens for HIV-1 vaccine deve

150 We detail the arsenal of nanocarriers and molecules available for sele

151 Recent advances in immunology and a growing arsenal of new drugs are bringing the focus of tolerance

152 the bacteroids are kept under control by an arsenal of nodule-specific cysteine-rich (NCR) peptides,

153 ill be a valuable complement to the existing arsenal of nucleophiles in Pd-catalyzed allylic substitu

154 ill be a valuable complement to the existing arsenal of nucleophiles with applications in allylic sub

155 new CRY2-based approaches expand the growing arsenal of optogenetic strategies to probe cellular func

156 re represents a valuable new addition to the arsenal of pharmacological tools competent to investigat

157 Among the arsenal of plant-derived compounds activated upon attack

158 iew, we discuss differences between the CWDE arsenal of plant-pathogenic and non-plant-pathogenic fun

159 The arsenal of pneumococcal adhesins interacts with a multit

160 as Nup98, may be an additional weapon in the arsenal of poliovirus and perhaps other picornaviruses t

161 vasion strategy, which is predicated upon an arsenal of potent inhibitory proteins.

162 VSV is one oncolytic virus out of an arsenal of potential candidates shown to provide selecti

163 been a very promising recent addition to our arsenal of potentially useful drugs for epigenetic thera

164 d potato (Solanum tuberosum), has evolved an arsenal of protease inhibitors to overcome the action of

165 The release of their formidable arsenal of proteases and other toxic intracellular conte

166 CMV encodes a diverse arsenal of proteins focused on altering and/or mimicking

167 creens reveal that the host cells express an arsenal of proteins that inhibit replication of plus-str

168 ms a complex array of functions using a vast arsenal of proteins, ion channels, pumps, motors, signal

169 ms a complex array of functions using a vast arsenal of proteins, ion channels, pumps, motors, signal

170 The DhMRE genome encodes an arsenal of putative regulatory proteins with eukaryotic-

171 Actinobacillus actinomycetemcomitans, has an arsenal of putative virulence determinants that account

172 fills one of the last remaining gaps in the arsenal of radical cyclizations.

173 This work increases the arsenal of reactions and strategies available for the sy

174 ponse, selection favors hosts with a broader arsenal of recognition molecules, thus favoring diploid

175 20C to be another tool that is unique in the arsenal of S. pneumoniae and that it may implement the e

176 Fungi and bacteria compete with an arsenal of secreted molecules for their ecological niche

177 ure comparison and classification, given the arsenal of sequence comparison tools developed by comput

178 h-throughput dPCR provides a new tool in the arsenal of single-cell analysis methods, with a unique c

179 Our results revealed a substantial arsenal of small molecules induced by microbial interact

180 Pathogenic bacteria are endowed with an arsenal of specialized enzymes to convert nutrient compo

181 A whole arsenal of statistical tools can be used to deal with in

182 and provides a novel addition to the growing arsenal of structurally diverse irreversible ligands tha

183 ealing alternative to the currently employed arsenal of surface modification methods consisting mainl

184 Compared with the well equipped arsenal of surface modification methods for flat surface

185 sitions of the thiazole ring, broadening the arsenal of synthetic methods to obtain such scaffolds.

186 the last 10 years from the rapidly expanding arsenal of system-wide genomic methodologies.

187 and development efforts have created a large arsenal of targeted and chemotherapeutic drugs for preci

188 h work is focused upon the development of an arsenal of targeted therapies, towards oncogenic driver

189 rin and its potential impurities adds to the arsenal of techniques available for the rapid identifica

190 expression and covalent modification to the arsenal of techniques for characterizing the dynamic, im

191 Here, we review the current arsenal of techniques used to query chromosome structure

192 Despite the arsenal of technologies employed to control foodborne no

193 the validity of our approach and expands the arsenal of the crystallization chaperone toolkit, which

194 partment has emerged as the frontline in the arsenal of the host's antiviral defenses.

195 ish them as essential tools in the technical arsenal of the modern biochemist.

196 abel-free detection differs greatly from the arsenal of the so-called traditional 7TM techniques comm

197 nderlying mechanisms, demands a multifaceted arsenal of therapeutic strategies.

198 ide new opportunities to augment the limited arsenal of therapeutics against influenza.

199 In this review, we outline the existing arsenal of therapies available for AMD and discuss the a

200 The current arsenal of tools and methods for the continuous monitori

201 transposition is a valuable addition to the arsenal of tools available for molecular biology and gen

202 re, glycerotoxin is a unique addition to the arsenal of tools available to unravel the mechanism cont

203 s suggests that MAb 201 may be useful in the arsenal of tools to combat SARS.

204 Fragment-based approaches have added to the arsenal of tools used to identify novel developable lead

205 The pediatric dermatologist's arsenal of topical anesthetic preparations is increasing

206 Clinically, a large arsenal of topoisomerase inhibitors has been used to sup

207 g white blood cell in humans, and contain an arsenal of toxic substances that kill and degrade microb

208 obe Clostridium perfringens produces a large arsenal of toxins that are responsible for histotoxic an

209 re currently under development to add to our arsenal of treatment strategies in this devastating dise

210 The arsenal of treatments for most cancers fit broadly into

211 efficacious and tolerable than the available arsenal of treatments.

212 Bacteremia isolates exhibit an arsenal of VFs that distinguishes them from rectal isola

213 Its ability to persist likely is due to its arsenal of viral immunoevasion proteins.

214 thin its genome that temporally regulate its arsenal of virulence determinants throughout its virulen

215 The arsenal of virulence factors deployed by streptococci in

216 Its arsenal of virulence factors includes a secreted hemaggl

217 pathogenicity of P. aeruginosa is due to the arsenal of virulence factors produced by the pathogen an

218 This bacterium deploys an arsenal of virulence factors that act in concert to prom

219 um Porphyromonas gingivalis, produces a vast arsenal of virulence factors that compromise human defen

220 erial pathogens have evolved a sophisticated arsenal of virulence factors to modulate host cell biolo

221 Group A Streptococcus (GAS) has acquired an arsenal of virulence factors, promoting life-threatening

222 g biofilm formation and the production of an arsenal of virulence factors.

223 S. aureus adapts the expression of its broad arsenal of virulence genes to promote different types of

224 icts can point to possible weaknesses in the arsenal of viruses and may lead to the rational design o

225 ect to continuous damage and the cell has an arsenal of ways of responding to such injury.

226 The abundance and diversity of this potent arsenal of weapons are clear.

227 and how do microorganisms respond to such an arsenal of weapons?

228 y metabolism and defending themselves via an arsenal of xenobiotic metabolizing enzymes.

229 his powerful and practical route adds to the arsenals of chemists and biologists interested in the sy

230 Xanthomonas, and Ralstonia spp. harbor large arsenals of effectors.

231 Plants possess large arsenals of immune receptors capable of recognizing all

232 international effort aimed at destroying the arsenals of nerve agents, including soman and sarin.

233 us with many microorganisms possessing large arsenals of predicted multidrug efflux transporters.

234 tome and chordate invertebrates harbor large arsenals of recognition receptors primarily encoding LRR

235 Venoms are complex biochemical arsenals, often containing hundreds to thousands of uniq

236 the infectious necrotroph of its pathogenic arsenal or attenuates its effect, restricting further in

237 esent only a portion of the virulence factor arsenal possessed by P. aeruginosa.

238 Persian Gulf War, Iraq's biological warfare arsenal probably would have been militarily ineffective

239 Among the current arsenal, SM fluorescence techniques have capabilities of

240 In addition to expanding the anti-HIV arsenal, small-molecule inhibitors against untargeted HI

241 re extended and sophisticated methodological arsenal than is the case currently.

242 ly reinforcing components of the immunologic arsenal that the host mobilizes to defend itself against

243 (2) could be an important new therapy in the arsenal to fight metastatic breast cancer.

244 e invention and diversification of molecular arsenals, which, in turn, promote the cellular co-option

245 pigenomic testing into the clinical research arsenal will greatly facilitate our understanding of the