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1 GDM was associated with a series of retinal arteriolar abnormalities, including narrower caliber, re
4 nge of adjustment, increasing diameter (8.5% arteriolar and 21% total venous area) with hypoxia (40 m
5 O2; P < 0.001) and decreasing diameter (6.9% arteriolar and 23% total venous area) with hyperoxia (50
6 suggest that TMEM16A plays a general role in arteriolar and capillary blood flow and is a promising t
8 y functionally restores the perfusion at the arteriolar and capillary level and wall shear stress in
9 e metabolic syndrome has focused on arterial/arteriolar and capillary levels, investigation into venu
10 l microscopy, we found that after mesenteric arteriolar and carotid artery injury, Slit2 delayed vess
13 t of phenotypic associations between retinal arteriolar and venular calibers and cardiovascular disea
19 of skin and muscle microcirculation, retinal arteriolar and venular diameter, and markers for cerebra
20 lood pressure, functional capillary density, arteriolar and venular diameter, and Po2 tension distrib
24 icroscopy provided PO(2) measurements at the arteriolar and venular ends of capillaries in the hamste
29 ble distribution of blood flow at successive arteriolar bifurcations in metabolic syndrome creates an
30 We then simulated blood-plasma separation in arteriolar bifurcations with different bifurcation angle
31 is activated by hydrodynamic forces found in arteriolar bleeding to promote hemostasis, whereas uncle
32 ed with marked decreases (mean: 60%) of pial arteriolar blood flow attributable to vasoconstriction a
35 hypothesized that autoregulatory changes in arteriolar blood volume (aBV) that develop distal to a s
36 showed that cocaine interrupted CBF in some arteriolar branches for over 45 min and this effect was
37 f; 95% CI: -0.02 Df, -0.001 Df;), and larger arteriolar branching angle (1.8 degrees ; 95% CI: 0.3 de
38 , 12.8) and had significantly larger retinal arteriolar branching angle (10.1 degrees, 95% CI: 1.4, 1
39 ther adjusting for traditional risks of GDM, arteriolar branching angle remained significantly larger
41 ese changes did not appear at the 45 degrees arteriolar branching until the flow rate was increased a
45 he highest abundance of omental and parietal arteriolar C1q, C3d, terminal complement complex, and ph
47 dies to better characterize the preferential arteriolar C4d staining may identify a renal compartment
49 munication occurs through the suppression of arteriolar [Ca2+]i oscillations and corresponding vasomo
50 nal education, mothers with GDM had narrower arteriolar caliber (-1.6 mum; 95% Confidence Interval [C
51 trol tended to have marginally wider retinal arteriolar caliber (6.0 mum, 95% CI: -0.9, 12.8) and had
52 ke from all sources had a 1.05-microm larger arteriolar caliber (P for trend = 0.012) and a 1.11-micr
53 ve disorders tended to have narrower retinal arteriolar caliber (standard deviation score: -0.13, 95%
54 Dietary fiber was related to wider retinal arteriolar caliber and narrower venular caliber, which a
57 al arterioles (0.98-mum narrowing of retinal arteriolar caliber per SD increase in GI, P = 0.01).
62 s laboratory has shown that adenosine causes arteriolar constriction and degranulation of mast cells
63 for the right eye and 0.8 for the left eye, arteriolar constriction in both eyes, retinal edema in t
64 fusate oxygen level raised from 0 to 21%, 2A arteriolar constriction in Young (11 +/- 1 microm) was g
66 able pressure amplification characteristics, arteriolar constriction, microcirculatory rarefaction, m
68 P epoxygenase expression attenuates afferent arteriolar constrictor reactivity and hypertension-induc
71 ved reduced fibrosis and increased capillary/arteriolar density along with reduced ventricular remode
75 -limb tissue, skeletal muscle blood flow and arteriolar density increased progressively between days
78 nt, the greater the reduction was in retinal arteriolar diameter (beta = -8.61; r2 = 0.335; F1,83 = 7
79 S component related to reductions in retinal arteriolar diameter (rp[85] = -0.661; P < .001), and imp
81 sex differences prevail in the regulation of arteriolar diameter in response to muscle contractions.
82 th muscle contractions (2, 4 and 8 Hz; 30 s) arteriolar diameter increased similarly across age-group
83 h MetS had significant reductions in retinal arteriolar diameter relative to adolescents without MetS
84 treatment significantly attenuated afferent arteriolar diameter responses to angiotensin in hyperten
86 group A hearts was markedly lower, but mean arteriolar diameter was significantly greater (34%) comp
87 SnPP), on brain electrical activity and pial arteriolar diameter were examined using quantitative ele
88 s were associated with reductions in retinal arteriolar diameter, a proxy for cerebral microvascular
90 also demonstrated associations with retinal arteriolar diameter, suggesting that the observed WM pat
95 we found wider venular diameters and smaller arteriolar diameters were both predictive of the 16-year
96 is mechanism is likely to play a role in the arteriolar dilatation and impaired vascular reactivity a
99 on measured as flicker light-induced retinal arteriolar dilation and heat-induced skin hyperemia.
100 id abolished SAH-induced eHACSs and restored arteriolar dilation in SAH brain slices to two mediators
103 mechanism by which I/R inhibits NO-mediated arteriolar dilation is through increased arginase activi
105 monocarboxylate transporters causes retinal arteriolar dilation predominantly via stimulation of NO
106 rog/mL, 60 minutes) significantly attenuated arteriolar dilation to endothelium-dependent NO-mediated
107 e data suggest that adenosine evokes retinal arteriolar dilation via activation of A(2A) receptors an
108 grade hyperpolarization that causes upstream arteriolar dilation, increasing blood flow into the capi
111 we determined flicker light-induced retinal arteriolar %-dilation (Dynamic Vessel Analyzer), heat-in
112 a glucose were associated with lower retinal arteriolar %-dilation and skin %-hyperemia in fully adju
115 gh the pathological processes leading to the arteriolar disease are associated with vascular risk fac
116 uence of hypertension, is linked to cerebral arteriolar disease through poorly defined mechanisms.
117 ge, characterized by salt-sensitivity, renal arteriolar disease, and blunted renal autoregulation, de
119 and 21 weeks p.i. HC alone caused temporary arteriolar dysfunction and venular leukocyte and platele
121 demonstrate that Ang-1 stimulates pulmonary arteriolar endothelial cells through a TIE2 (receptor wi
122 lular components of the HSC niche, including arteriolar endothelial cells, CXCL12-abundant reticular
125 we determined the role of Tregs in coronary arteriolar endothelial dysfunction in angiotensin II-dep
126 are important in the development of coronary arteriolar endothelial dysfunction in hypertension.
127 ease, which participates in reduced coronary arteriolar endothelial-dependent relaxation in response
130 essentially eliminates fluid shear stress on arteriolar endothelium throughout the entire cardiac cyc
136 lly associated with narrower central retinal arteriolar equivalent (beta = -2.04; P = .09); beta-bloc
137 cantly associated with wider central retinal arteriolar equivalent adjusting for refraction, photogra
139 ents without MetS (mean [SD] central retinal arteriolar equivalent, 182.35 [16.10] vs. 198.62 [19.03]
141 OX-1 and CD32 blockade prevented CRP-induced arteriolar expression of plasminogen activator inhibitor
144 Interval [CI]: -3.1 mum, -0.2 mum), reduced arteriolar fractal dimension (-0.01 Df; 95% CI: -0.02 Df
146 ntribution of renal vascular SEH to afferent arteriolar function in angiotensin hypertension was also
148 markers, endothelium-dependent vasodilation, arteriolar glycocalyx size, and glomerular barrier prope
149 interstitial fibrosis (CI), tubular atrophy, arteriolar hyaline thickening, fibrous intimal thickenin
152 with death-censored graft survival, whereas arteriolar hyalinosis and vascular intimal thickening di
153 clerosis, mesangiolysis, microaneurysms, and arteriolar hyalinosis associated with massive proteinuri
157 hronic allograft damage index parameters and arteriolar hyalinosis scores was called chronic damage i
158 the 1-, 5-, and 10-year prevalence moderate arteriolar hyalinosis was similar: CSA was 5.4%, 38.4%,
159 al mesangial matrix increase, 32.0% abnormal arteriolar hyalinosis, and 32.9% abnormal vascular intim
160 J db/db mice exhibited dramatic albuminuria, arteriolar hyalinosis, increased glomerular basement mem
161 n, albuminuria, and renal insufficiency with arteriolar hyalinosis, mesangial matrix expansion, mesan
162 proaching nodular glomerulosclerosis), focal arteriolar hyalinosis, mesangiolysis, and focal mild int
171 any effect on flow-mediated vasodilatation; arteriolar l-arginine content was also not different bet
172 was a significant intergroup difference for arteriolar length density (P=0.03) and diameter (P=0.03)
173 d blood flow was due to a large reduction in arteriolar length density and small arterioles in PTU-S
174 short axis (diameter) compensated for lower arteriolar length density and was the principal anatomic
175 (40%) and remote (14%) regions and a higher arteriolar length density in the septum (62%), despite a
179 e, progression, and clinical significance of arteriolar lesions in 1239 renal transplant sequential p
180 d biopsies for cause in individual patients, arteriolar lesions in renal transplants not only increas
184 PH) is characterized by complex precapillary arteriolar lesions, which contain phenotypically altered
185 ar phenotype was more florid, with pulmonary arteriolar luminal obliteration by apoptosis-resistant p
186 terial and venous occlusive disease, retinal arteriolar macroaneurysm formation and embolic events.
187 rwent retinal photography from which retinal arteriolar (mean, 153.75 +/- 22.1 mum, SD) and venular (
188 rdial blood flow (fluorescent microspheres), arteriolar morphometry, and gene expression (Western blo
189 right ventricular hypertrophy and pulmonary arteriolar muscularization in monocrotaline-challenged a
190 animals also exhibited significant pulmonary arteriolar muscularization in response to monocrotaline
193 n VSMCs and plays an active role in both the arteriolar myogenic response and during changes in vascu
196 nce of retinal focal arteriolar signs (focal arteriolar narrowing and arteriovenous nicking) and reti
197 ity is independently associated with retinal arteriolar narrowing and attenuated vascular pulsation a
199 as a tendency toward bilateral retinal focal arteriolar narrowing being more strongly associated with
201 al microvascular disease: retinopathy, focal arteriolar narrowing, arteriovenous nicking, and the art
205 ypes exhibit heterogeneity among branches of arteriolar networks in a locomotor muscle and that the n
206 ittle is known of AR subtype distribution in arteriolar networks of locomotor skeletal muscles, parti
207 t functional alphaAR subtype distribution in arteriolar networks of skeletal muscle varies with muscl
208 and computational modeling to define a novel arteriolar niche for quiescent HSCs within the bone marr
210 dent production of vasoconstrictors mediates arteriolar O2 reactivity, with significant regional hete
211 elieved to result from an intrinsic cerebral arteriolar occlusive disease, little is known about how
216 (overall risk, 3.9%), women in the narrowest arteriolar quartile had a 10-year event rate of 5.6% com
217 f cardiopulmonary bypass (CPB) on peripheral arteriolar reactivity and associated signaling pathways
220 this review is on local mechanisms modifying arteriolar resistance to match blood flow to metabolism.
221 have a novel function in regulating afferent arteriolar resistance under physiologic conditions.
223 important determinants of vascular tone and arteriolar resistance, but the mechanisms that modulate
224 his signalling flexibility in the integrated arteriolar response that underlies functional hyperaemia
226 ar transport rates, and exaggerated afferent arteriolar responses to angiotensin II and endothelin I.
229 re, proximal tubular transport, and afferent arteriolar responsiveness via an estrogen-dependent mech
231 With the exception of microinfarcts and arteriolar sclerosis, all neuropathologies were associat
232 - and microscopic infarcts, atherosclerosis, arteriolar sclerosis, and cerebral amyloid angiopathy),
234 the total number, length and surface area of arteriolar segments (diameter, 10-50 microm) were not si
237 evaluated for the presence of retinal focal arteriolar signs (focal arteriolar narrowing and arterio
238 ongest association was found between retinal arteriolar signs and a heavier WMH load, specifically in
240 ar risk factors, we found that retinal focal arteriolar signs, but not retinopathy lesions, were sign
241 ally induced vasodilation and suppression of arteriolar SMC Ca2+, without affecting the astrocytic Ca
245 xm1(-/-) lungs exhibit severe hypertrophy of arteriolar smooth muscle cells and defects in the format
246 optogenetics, Hill et al. (2015) report that arteriolar smooth muscle cells are key players in regula
247 llenge known to induce the transformation of arteriolar smooth muscle cells into renin-expressing cel
248 juxtaglomerular cells and the plasticity of arteriolar smooth muscle cells to re-express renin when
250 CNS, we find TRPV1 expression in a subset of arteriolar smooth muscle cells within thermoregulatory t
251 egrin activation, native CaL channels in rat arteriolar smooth muscle exhibit potentiation that is co
255 gerated pulmonary eosinophilia and pulmonary arteriolar smooth-muscle hyperplasia compared with PGE(2
257 t with early diabetic nephropathy, including arteriolar thickening, tubular dilation and atrophy, glo
261 collagen receptor glycoprotein VI (GPVI) in arteriolar thrombus formation was studied in FcRgamma-nu
263 ay that couples changes in PO2 to changes in arteriolar tone (the mechanism of action) remain unclear
264 ptional inhibitor DRB, prevented the reduced arteriolar tone and the enhanced CYP-mediated FID caused
267 ntraocular pressure (IOP), decreased retinal arteriolar tortuosity (odds ratio [OR], 1.73; 95% confid
268 Each SD increase in apoB was associated with arteriolar tortuosity only (1.75 x 10(-5); P = 0.050).
271 10 OIR model, a model with relevance to ROP, arteriolar tortuosity, and venous dilation are increased
275 This potentiates an exaggerated afferent arteriolar vasoconstricting response to angiotensin II a
276 st that a neuronal inhibition and concurrent arteriolar vasoconstriction correspond to a decrease in
277 al SI, a blood oxygenation/flow decrease and arteriolar vasoconstriction in the presence of increased
278 AGBM-Ab as a result of afferent and efferent arteriolar vasoconstriction with consequent reductions i
281 < 0.001 for apoAI) and flicker-light retinal arteriolar vasodilatation (0.33%; P = 0.003) and was ass
282 opposes the development of impaired coronary arteriolar vasodilatation during simultaneous high-fat f
283 the integrated muscle contraction-dependent arteriolar vasodilatation is coupled through an endothel
284 ssess endothelium-dependent and -independent arteriolar vasodilation and venular leukocyte and platel
287 y 100 ms) was significantly smaller than the arteriolar-venular transit time ( approximately 500 ms),
288 scopic images demonstrated significant brain arteriolar vessel constriction, decreased functional cap
290 dic device that mimics a network of stenosed arteriolar vessels, permitting evaluation of blood clott
292 ular bone and sinusoidal space and decreased arteriolar volume in this model were associated with dec
294 DI accumulation at the site of laser-induced arteriolar wall injury is markedly reduced in beta3-null
299 arrowing from inwards collapse of hyalinized arteriolar walls unable to maintain its structural integ
300 dilated capillaries, hypertensive changes in arteriolar walls, anomalous and misaligned pulmonary vei
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