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1 HIV, eradication of the virus from the body, as a means to a cure, remains in progress.

2 poptosis in renal tumours and suggest ORCTL3 as a means to accomplish this.

3 e among adults and to reduce SSB consumption as a means to accomplish weight loss or avoid excess wei

4 t data transformation and feature extraction as a means to achieve a more accurate prediction.

5 ylglycerol (TAG) in their vegetative tissues as a means to achieve a step change in oil yield.

6 ons of easily prepared propargyl propiolates as a means to achieve effective intermolecular coupling

7 High sun exposure is to be avoided as a means to achieve high vitamin D status.

8 tructure, rather than active site chemistry, as a means to achieve modulate function.

9 tructure, rather than active site chemistry, as a means to achieve modulate function.

10 programming of cells has attracted attention as a means to achieve organ regeneration.

11 use of passively-recorded acoustic emissions as a means to achieve this control.

12 anscytotic pathway for further investigation as a means to achieve transmucosal delivery of nanoparti

13 f genomic instability in BE biopsy specimens as a means to add supplementary information to the histo

14 Semantic web technologies are here explored as a means to address some of these problems.

15 ls and ICP-MS data and the results evaluated as a means to address the issue of determining nanoparti

16 e of a result depends on, has been suggested as a means to aid the interpretation of trial results.

17 he development of herpetic stromal keratitis as a means to alleviate further neovascularization and t

18 m-based vaccines targeting reservoir species as a means to alleviate the burden of Chagas disease in

19 nimally invasive surgery has been introduced as a means to allow manipulation of delicate tissues wit

20 aperone HSP90 has been extensively discussed as a means to alter phenotype in many traits and organis

21 tivators--i.e. undertaking physical activity as a means to an end, which included the opportunities t

22 of this study is to present proportionality as a means to analyse relative data, it also raises intr

23 ed by decreased nutrient levels, potentially as a means to anticipate starvation.

24 Nanoscale pores have proved useful as a means to assay DNA and are actively being developed

25 Fragment Length Polymorphism (AFLP) markers as a means to assess small-scale genetic heterogeneity b

26 Here we use copper binding as a means to assess the number of binding sites remaini

27 targeting the phosphatase activity of QseC, as a means to attenuate a wide range of QseC-bearing pat

28 ansiently exposes the substrate binding site as a means to become rapidly poised for binding to their

29 genotyping with functional Ab profiling data as a means to better predict and optimize humoral respon

30 d infinitesimal model in computer simulation as a means to better represent the genetic architecture

31 As a means to better understand its enzymatic function,

32 existing single-locus DNA barcoding methods as a means to better understand the diversity of the liv

33 compounds inhibiting adenovirus replication as a means to block adenovirus-induced pathology.

34 s provide a strong rationale to target Hsp90 as a means to block radiation-induced HIF-1alpha and thu

35 accination of plasma donors was investigated as a means to boost titers.

36 scene is perceived salient for many animals as a means to break camouflage.

37 ped to quantify the oxidative activity of PM as a means to characterize its ability to induced oxidat

38 we report the use of polymer-drug conjugates as a means to co-deliver synergistic doses of top I and

39 nd Long-term PAH Disease Management (REVEAL) as a means to compare observed mortality with predicted

40 is a large interest in LNG as a marine fuel, as a means to comply with sulfur and NOX regulations.

41 city, that operate in contemporary organisms as a means to consider physiological responses that are

42 Our ability to harness glycosylation as a means to control biological systems is hampered by

43 A photoresponsive surfactant has been used as a means to control protein structure and dynamics wit

44 nhibition of Dock2 has therapeutic potential as a means to control recruitment of pathogenic lymphocy

45 is applied to the design of genetic circuits as a means to control regulator activity and degradation

46 ural and electronic match in anion receptors as a means to control the arrangement and binding streng

47 Phosphorylation has been hypothesized as a means to control the assembly/disassembly of liquid

48 explore the possibility of diffusiophoresis as a means to control the colloid transport in dead-end

49 semiconductor donor-acceptor (DA) interface, as a means to control the magnitude and sign of chi((2))

50 Vaccination of poultry has been used as a means to control the spread and impact of the virus

51 int hydrogen bonding and metal complexation, as a means to control the step-by-step assembly of a pan

52 pendency of splicing on the EJC is exploited as a means to control the temporal order of splicing eve

53 enes in mosquitoes that could be manipulated as a means to control vector-borne disease.

54 air is required to maintain genome stability as a means to counter the accumulation of unusual bases

55 air is required to maintain genome stability as a means to counter the accumulation of unusual bases

56 ar to activate intrinsic antioxidant systems as a means to counteract oxidative stress.

57 ecoys termed 'miRNA sponges' were introduced as a means to create loss-of-function phenotypes for miR

58 ept of "treatment as prevention" has emerged as a means to curb the global HIV epidemic.

59 g and characterization in cluster chemistry, as a means to decouple cluster formation, discovery, and

60 Intradermal IPV shows promise as a means to decrease the effective dose and cost of IP

61 pected Pseudomonas aeruginosa (PA) infection as a means to decrease the likelihood of administering i

62 xplored the analysis of acquisition dynamics as a means to define memory components and revealed stro

63 ubunits and establish pentameric concatemers as a means to delineate interactions between subunits th

64 As a means to delineate the effect of NK cells on SIV in

65 al gene counting of RNA transcripts in urine as a means to detect prostate cancer.

66 indings illustrate the use of gene-profiling as a means to determine early molecular events that may

67 support the use of Doppler echocardiography as a means to diagnose cardiac involvement in acute rheu

68 e of planar-twinned Ag triangular nanoprisms as a means to dictate Au NP twin structure.

69 ping sets of genes, often at distinct sites, as a means to differentially regulate target gene expres

70 agnostic sulfate and phosphate OH stretches, as a means to differentiate sulfated from phosphorylated

71 manent molar (M1), which can therefore serve as a means to directly compare the life histories of fos

72 least squares discriminant analysis (PLS-DA) as a means to discriminate authentic rosehip oil from ad

73 smaller thiols was intracellularly assessed as a means to disrupt the balance of reactive oxygen spe

74 ent stable isotope ratios have been assessed as a means to distinguish between fermented cocoa beans

75 hat cooperative melting behavior can be used as a means to distinguish the relative propensities for

76 aft engines and auxiliary power units (APUs) as a means to diversify fuel supplies and reduce emissio

77 between these two regulatory systems evolved as a means to divert energy in times of need from organi

78 on its distinctive biological features, and as a means to drive development of new drugs and vaccine

79 - glucose clamps and in vivo microdialysis - as a means to dynamically modulate blood glucose levels

80 methods are slow, antiquated, and expensive as a means to effectively reduce the virus burden during

81 eme utilizing oxime chemistry was identified as a means to efficiently conjugate different peptide sp

82 gmatic method to slow vitamin A dimerization as a means to elucidate the pathogenesis of macular dege

83 Segregated H is used as a means to emphasize differences in the selected grai

84 rare cells from peripheral blood has emerged as a means to enable noninvasive diagnostics and develop

85 try have been suggested in photonic settings as a means to enforce stable energy flow in platforms th

86 he hairpin gamma-aminobutyric acid turn unit as a means to enhance cellular uptake and biological act

87 dies support the blocking of PD-L1 signaling as a means to enhance combined immunotherapy approaches

88 nd the manipulation of the coral microbiome) as a means to enhance environmental stress tolerance of

89 ht the potential of stimulating neurogenesis as a means to enhance learning.

90 As a means to enhance persistence of infused T cells in

91 within the vascular phloem of mature tissues as a means to enhance phloem loading and systemic spread

92 We hypothesize flavonoid treatment as a means to enhance the glyoxalase pathway's ability t

93 SIV(+)PD-1(hi) CD4 T cells at mucosal sites as a means to enhance viral control.

94 mpact of modulating CDPK activity in sorghum as a means to enhanced abiotic stress tolerance, we intr

95 ' of sour and bitter neural pathways evolved as a means to ensure that high levels of salt reliably t

96 ytes with a defined specificity and function as a means to eradicate cancer.

97 bination antiretroviral therapy was proposed as a means to eradicate viral reservoirs.

98 using perturbation-free fluctuation analysis as a means to establish causality among cellular events.

99 t extent of disease (PRETEXT) staging system as a means to establish consensus classification and ass

100 epithelia and neurons use mRNA localization as a means to establish polarity.

101 ith that currently accessible in gene banks, as a means to estimate the comprehensiveness of the cons

102 er we use feature-based sensitivity analysis as a means to estimate the impact of variation in key ap

103 enerate in vivo models, which can also serve as a means to evaluate targeted therapies based on their

104 review drug influences in challenge studies as a means to examine acute influences on reward process

105 The Toffoli and Fredkin gates were suggested as a means to exhibit logic reversibility and thereby re

106 ns highly sought after on polymeric surfaces as a means to expedite diffusional search processes in m

107 nts designed for other clinical applications as a means to expedite efforts involving therapeutic tra

108 n products, we used the antibiotic puromycin as a means to experimentally manipulate prematurely term

109 " strategy should be particularly attractive as a means to explore latent electrophiles not typically

110 tudies of hRSV have used subcellular imaging as a means to explore the changes in localization of ret

111 As a means to explore the influence of the nucleic acid

112 This suggests that TIPS could be used as a means to extend posttransplant survival but should

113 ic IgG, show some promise in clinical trials as a means to extend the therapeutic potential of antibo

114 loud point extraction was optimized and used as a means to extract and preconcentrate all nanoparticl

115 utilize ATM activity to increase HR activity as a means to facilitate viral replication.

116 in climate and the utility of our framework as a means to forecast continental-scale patterns of veg

117 cribed and tested herein shows great promise as a means to further characterize the structure and com

118 As a means to gain an understanding of these host-biofil

119 ria emit and sense chemical signal molecules as a means to gauge population density and control gene

120 ds has been recently reignited, particularly as a means to generate a band gap in graphene.

121 not only as a clearance mechanism, but also as a means to generate bioactive versican fragments.

122 work, we develop the electro-Fenton reaction as a means to generate hydroxyl radicals for structural

123 nature of nonuniformity at each length scale as a means to guide ongoing research efforts and highlig

124 ese data introduce class IIa HDAC inhibition as a means to harness the anti-tumour potential of macro

125 of Anopheles mating preferences in the wild as a means to harness them in the implementation of popu

126 e on how these studies came to be is offered as a means to highlight the 25th anniversary of these di

127 chronic HF in both humans and animal models as a means to highlight the gap in our knowledge base th

128 in the use of brain interfacing technologies as a means to human augmentation.

129 ime, we conclude that selection for throwing as a means to hunt probably had an important role in the

130 monstrate the utility of eyelid conditioning as a means to identify and characterize the rules that g

131 either as part of a diagnostic algorithm or as a means to identify high-risk individuals for prospec

132 nto families based on seed sequence identity as a means to identify possible functional redundancy.

133 of aptamers obtained by cell-SELEX can serve as a means to identify promising biomarker candidates an

134 al classification schemes have been proposed as a means to identify sites in the oral cavity where im

135 ific subpopulations of cortical interneurons as a means to identify some of these missing factors.

136 As a means to identify the active PMEs in seed coat muci

137 e regeneration of epicardial tissue ex vivo, as a means to identify therapeutic targets for heart dis

138 analytic approach holds considerable promise as a means to identify time-varying risk factors associa

139 and that increased copper uptake can be used as a means to image prostate tumors.

140 X-rays are commonly used as a means to image the inside of objects opaque to visi

141 o-photon (2P) fluorescence has been explored as a means to image voltage in tissue.

142 uit of alternatives to toxic As is important as a means to imparting a technologically safe and effec

143 Patients frequently inquire about exercise as a means to improve bone strength and reduce osteoporo

144 ussed and paths to reduction of toxic lipids as a means to improve cardiac function are suggested.

145 Telomere extension has been proposed as a means to improve cell culture and tissue engineerin

146 ts do not support the use of adhesive strips as a means to improve cosmetic outcomes or reduce scar w

147 ion of lignin biosynthesis has been proposed as a means to improve forage and bioenergy crops, but fr

148 for-performance (P4P) is increasingly touted as a means to improve health care quality.

149 g tested, but rational sequence modification as a means to improve immune responsiveness has been neg

150 ce reduction, and has great policy potential as a means to improve intergroup relations, because it c

151 Biodegradable scaffolds have been proposed as a means to improve matrix deposition and the biomecha

152 d points to correcting calcineurin signaling as a means to improve memory during aging.

153 Our data suggest the systematic use of ECFCs as a means to improve MSC transplantation.

154 sing antiangiogenic agents has been proposed as a means to improve radiation therapy by enhancing tum

155 attle Angina Questionnaire, should be tested as a means to improve recognition of angina and, potenti

156 consider molecular characterization of HGPIN as a means to improve risk stratification.

157 Freeze drying of the NPs was also evaluated as a means to improve shelf life.

158 re surface structure on cathodes can be used as a means to improve the performance of lithium-oxygen

159 n investigated over the last several decades as a means to improve upon the lack of tumor targeting a

160 -wide association studies have been proposed as a means to improving power for designs including fami

161 ribe 4-aza substitution on the xanthene core as a means to increase BACE1 potency while reducing hERG

162 c innervation of blood vessels could be used as a means to increase cerebral blood flow.

163 ased polymers have been extensively explored as a means to increase drug delivery systems' biocompati

164 lites that have related molecular structures as a means to increase functional diversity and gain an

165 ast-skeletal-troponin activator, CK-2017357, as a means to increase muscle strength by amplifying the

166 ted combining results across multiple panels as a means to increase power, but the methods employed m

167 inting (alternate reading frame utilization) as a means to increase protein diversity in genomes seve

168 this study, tumor hyperthermia was utilized as a means to increase the active delivery of heat shock

169 colonization with disease has been suggested as a means to increase the diagnostic precision.

170 increased uses in drug delivery applications as a means to increase treatment efficacy and improve pa

171 etc.) Urban farming (UF) has been advocated as a means to increase urban sustainability by reducing

172 asing focus on 'sustainable intensification' as a means to increase yields on underperforming landsca

173 way stimulation in neonatal and adult hearts as a means to induce cardiac regeneration after myocardi

174 The identification of SR1 and AHR modulation as a means to induce ex vivo HSC expansion should facili

175 nesis, and efforts to inhibit PAK1 signaling as a means to induce tumor cell apoptosis are underway.

176 t modulation of beta-cell miR-33a expression as a means to influence insulin secretion.

177 3 mRNA that directly interacts with hnRNP-Q1 as a means to inhibit Gap-43 mRNA translation.

178 logically modulate the eIF4E-cap interaction as a means to inhibit pathological EMT in the setting of

179 that can be added to a parthenolide regimen as a means to inhibit such compensatory events and there

180 cycled during treatment, has been suggested as a means to inhibit the evolution of de novo resistanc

181 additional magnetic field gradients, as well as a means to interact with the nuclear spin qubit.

182 se inhibitors, such as TIMP-4, holds promise as a means to interrupt the progression of post-MI remod

183 ministration strategies are being considered as a means to interrupt transmission of Plasmodium falci

184 tures transduced with recombinant lentivirus as a means to investigate the effects of various PS1 mut

185 hysical activity and not sedentary behaviour as a means to maintain or improve cardiorespiratory fitn

186 eturn, the immune system has largely evolved as a means to maintain the symbiotic relationship of the

187 iabatic driving protocols have been proposed as a means to make fast changes in the Hamiltonian witho

188 ot visual motion stimuli, corrupted by noise as a means to manipulate task difficulty, is frequently

189 rtunity to detect real-time metabolic fluxes as a means to measure metabolic treatment responses in v

190 pathological autoimmune responses, possibly as a means to mitigate inflammatory damage and preserve

191 tion of protein therapeutics in every detail as a means to mitigate risks of product quality related

192 at interfere with cholesterol/27HC synthesis as a means to mitigate the impact of cholesterol on brea

193 singly are focusing on allosteric modulators as a means to modify the activity of G protein-coupled r

194 munication is exploited by certain pathogens as a means to modify the host response in ways that favo

195 hyperventilated and then stopped breathing, as a means to modulate and expose to view important, but

196 is widely expressed in the CNS and can serve as a means to modulate pain perception, stress responses

197 us, pharmacological inhibition of the 20S CP as a means to modulate proteasome function toward therap

198 le range temperatures should be investigated as a means to modulate the inflammatory response in pati

199 used extensively in the scientific community as a means to monitor cell growth, location, morphology,

200 oton nuclear magnetic resonance spectroscopy as a means to monitor metabolism following albumin admin

201 he use of an alternating current (AC) signal as a means to monitor the conductance of an alpha-hemoly

202 orescence Lifetime Imaging Microscopy (FLIM) as a means to non-invasively identify tumor-associated m

203 n as deformation imaging, has been developed as a means to objectively quantify regional myocardial f

204 tructural candidates and reaction conditions as a means to obtain the highest enantiomeric excess (ee

205 r transport in the graphitic nanoenvironment as a means to offer a clean and sustainable source of en

206 Codon usage thus evolved as a means to optimise translation on individual mRNAs,

207 Wnt signaling and strengthen Notch signaling as a means to orchestrate cells for somite segmentation

208 tifies pretreatment biopsy in pediatric mHGA as a means to orient therapeutic efforts in this disease

209 d chemotherapies for TISC are in development as a means to overcome cellular resistance and mechanism

210 Further, N-terminal acetylation was offered as a means to overcome the interference problem by shift

211 ltrashort (approximately 30 fs) laser pulses as a means to overcome the limitations of current techno

212 As a means to overcome this capacity crunch, space-divis

213 ctivate and establish the ambient K(+) level as a means to populate the inactivated state of KcsA in

214 reased performance of this surgical practice as a means to potentially improve health-related quality

215 ntrolled cationic polymerization has emerged as a means to precisely regulate polymer chain growth.

216 ransplantation of isolated ovarian follicles as a means to preserve fertility.

217 e investigations of supplemental nucleotides as a means to prevent a greater proportion of human neur

218 e developed novel 19-substituted BQA (19BQA) as a means to prevent arylation.

219 We targeted the RyR as a means to prevent disease progression, and sub-chron

220 ible defect that can potentially be targeted as a means to prevent plaque progression.

221 hould not be withheld from surgical patients as a means to prevent SSI.

222 nting disease, modulation of B cell function as a means to prevent type 1 diabetes has not been inves

223 vaccines that elicit neutralizing antibodies as a means to prevent virus acquisition.

224 kDa glycoprotein, to compare SEC and ESI MS as a means to probe composition of the complex mixture o

225 Here we use protein film voltammetry (PFV) as a means to probe the redox properties of mitoNEET and

226 at PA may form an octameric oligomeric state as a means to produce a more stable and active LT comple

227 f phenol nucleophiles to benzopyrylium salts as a means to produce enantioenriched flavonoid-like com

228 of fuel-oil combustion, in addition to coal, as a means to produce it.

229 e propose complementation by codon shuffling as a means to produce replication-defective or attenuate

230 roconvulsive therapy (ECT) has been proposed as a means to produce stimulation closer to the neural a

231 being successfully used by many institutions as a means to produce that integration through its use i

232 ansferase (Dnmt) enzymes have been advocated as a means to promote and stabilize Foxp3 expression in

233 peutic (ALN-AT3) targeting antithrombin (AT) as a means to promote hemostasis in hemophilia.

234 2 interaction suppresses basal host defenses as a means to promote systemic virus accumulation.

235 ons for the arrival of personalized medicine as a means to provide quality, customized, and effective

236 n reaction (qPCR) to detect HAdV genomic DNA as a means to quantify attachment and genome replication

237 s under a variety of experimental conditions as a means to quantify cell-to-cell transmission and ass

238 asurement of platelet adhesion to fibrinogen as a means to quantify the effect of the P2Y12 and alpha

239 ic and anoxic extractions have been proposed as a means to quantify the U(VI) and U(IV) content of se

240 ith symmetric progenitor divisions may serve as a means to rapidly repair injured tissue while preser

241 ng water, hydrogen, and oxygen, using theory as a means to rationalize catalyst performance.

242 ) suggest that interface effects can be used as a means to reach superconducting critical temperature

243 stem and progenitor cells has been explored as a means to reconstitute metabolic deficiencies in the

244 u detection and de novo assembly of WGS data as a means to reconstruct the full sequence of insertion

245 es distinguish augmentation of Rac1 activity as a means to rectify the pathologic angioarchitecture a

246 sized in the management of patients with CKD as a means to reduce cardiovascular risk and risk for CK

247 to therapies that lower plasma triglycerides as a means to reduce CVD events.

248 entions have been tested in cancer survivors as a means to reduce late effects and comorbidity, but f

249 al pertussis vaccination is being considered as a means to reduce the burden of infant pertussis in l

250 egnated dressings have become widely adopted as a means to reduce the risk for catheter-associated bl

251 ther, our findings identify deubiquitination as a means to regulate BRCA2 function and point to USP21

252 cans (GAGs) during the inflammation response as a means to regulate chemokine migration.

253 mpartmentalization, dynamics, and clustering as a means to regulate receptor signaling through contro

254 mechanical stability to the anastomosis, and as a means to release drug locally over prolonged period

255 perimental noise are examined and quantified as a means to remove their contributions via soft thresh

256 As a means to replicate human neuronal activity, repeate

257 e decision making process rather than merely as a means to report the decision.

258 , as opposed to single strand DNA annealing, as a means to restore an out-of-frame luciferase gene cl

259 Pacemakers have existed for decades as a means to restore cardiac electrical rhythms.

260 ls induce proliferation in neighboring cells as a means to restore homeostasis.

261 nsate for reduced torsinA activity in the ER as a means to restore homeostatic balance and neuronal f

262 gesting that adaptive introgression occurred as a means to resurrect adaptive variation that had been

263 ents and emerging adults prefer the Internet as a means to retrieve NSSI resources and that important

264 addition, ESC-derived TEPs may also have use as a means to reverse age-dependent thymic involution, t

265 estions, membrane curvature has been invoked as a means to segregate lipids and proteins in cellular

266 tial component of the SAC signaling cascade, as a means to selectively induce chromosome instability

267 Biased agonism has been proposed as a means to separate desirable and adverse drug respon

268 le to a wide range of VGICs and, thus, serve as a means to simplify and accelerate biophysical, struc

269 e utility of increasing Axin2 levels in CRCs as a means to slow tumor progression.

270 serve as an indicator of zDC expression and as a means to specifically deplete cDCs.

271 ocket depth of the toxin was probed and used as a means to specifically improve inhibition of the tox

272 w pervasive in biomedicine, where they serve as a means to standardize terminology, to enable access

273 purred the promotion of no-tillage practices as a means to stimulate carbon storage and reduce CO2 em

274 auxin and jasmonic acid biosynthetic enzymes as a means to strengthen plant immunity against biotroph

275 e and interpretation of species correlations as a means to study defence-herbivory relationships.

276 ioma (IH), the most common tumor of infancy, as a means to study VEGFR-1 activation in pathological v

277 ory resources, IS elements were investigated as a means to subtype this organism.

278 vical spinal cord injury and investigated it as a means to support personalized assistance and therap

279 of using mRNA from exfoliated cells in stool as a means to surveil the distal small intestine in a mu

280 Bacteria use urea as a means to survive in acidic environments and/or as a

281 newable feedstocks into chemicals is pursued as a means to sustainably fulfil future societal needs.

282 creasingly popular in low-impact development as a means to sustainably mitigate the environmental pro

283 findings support the idea of exploiting ROS as a means to target cancer cells and highlight LNM E1 a

284 may be a viable therapeutic avenue, as well as a means to test the role of RNA structure upon RAN tr

285 (LCI), measured by multiple breath washout, as a means to track disease progression in preschool chi

286 Our results establish RCas9 as a means to track RNA in living cells in a programmabl

287 cal implementation of HMGB1-specific therapy as a means to treat APAP-ALI and other inflammatory cond

288 tudies of pharmacologic potentiation of CFTR as a means to treat cystic fibrosis.

289 f probiotics has become increasingly popular as a means to try to improve health and well-being.

290 ent study, we used the Endosialin(-/-) mouse as a means to uncover novel roles for pericytes during t

291 stochastic models describing focus expansion as a means to understand and quantify the dynamics of HC

292 same alkyl side chains has been synthesized as a means to understand structure-property relationship

293 ance of studying the unfertilized MII oocyte as a means to understand the molecular pathways governin

294 As a means to understand the regulatory mechanisms contr

295 As a means to understand the role of domain 5 in PRRSV i

296 their employment in mobile applications and as a means to upgrade existing mass analyzers.

297 scriptome of B. burgdorferi grown in culture as a means to validate non-ORF associated promoters disc

298 Whole-body MRI has emerged as a means to visualize additional areas of involvement.

299 ical probes to proteins has long been sought as a means to visualize and manipulate proteins.

300 sion, we demonstrate the performance of OCME as a means to visualize tissue microarchitecture in beni

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