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2 ions at 50 degrees C led to high conversions as judged by (1)H NMR spectroscopy and relatively low di
3 Hfl) did not perturb beta-hairpin formation, as judged by (1)H NMR structures of four peptides determ
6 e periplasmic surface of the inner membrane, as judged by 4-5-fold reduced labeling with the inner me
8 ression produced a functional subsensitivity as judged by a blunted Fos induction response to a sub-s
9 ps 3 and 4 and with 1 or more exacerbations (as judged by a clinician based on patient records, histo
11 induced flavonoid accumulation in root tips, as judged by a dye that becomes fluorescent upon binding
12 rix (M) protein was specifically stimulated, as judged by a greater abundance of M protein and greate
13 ternary complex when N2,N2-Me2G was present, as judged by a reduced burst amplitude (5% of total enzy
15 cterized set of short antisense transcripts, as judged by a shift in the distribution of RNAP in BCM-
18 se obtained with more commonly used methods, as judged by a variety of analytical techniques and by c
20 ss of activity but not inactivation of heme, as judged by absorption spectroscopy and pyridine hemoch
21 7 is highly exposed to the membrane surface, as judged by accessibility to factor Xa of cleavage site
22 e here that HCV infection induces autophagy, as judged by accumulation of lipidated LC3-II, and that
23 he molecular hallmarks of the vertebrate AIS as judged by accumulation of the anchoring protein Ankyr
24 ted without glutamine were highly adaptable, as judged by additional robust adaptability assays invol
26 encies in auxin transport in the shoot apex, as judged by altered expression of PIN1, the auxin repor
27 treated spores failed to undergo germination as judged by an absence of cytological changes in spore
28 nic determinants common to the two antigens, as judged by an antigen reversal growth inhibition assay
29 quence of increased cellular redox potential as judged by an elevated ratio of oxidized to reduced gl
30 ional activity against blood-stage parasites as judged by an in vitro parasite Growth Inhibition Assa
31 ctivation stimulated mobilization of CTLA-4, as judged by an increase in cell surface expression; how
32 with a disproportionate increase in insulin as judged by an increased insulin-to-glucose iAUC ratio.
33 high expression of soluble monomeric protein as judged by analytical size-exclusion chromatography.
34 ctured and monomeric at slightly acidic pH's as judged by analytical ultracentrifugation, gel filtrat
35 from toxic concentrations of nicotinic acid as judged by analyzing the growth of the corresponding m
36 3 y has not increased malaria transmission, as judged by annual point prevalence surveys in 1- to 4-
37 t GPIHBP1 proteins reached the cell surface, as judged by antibody binding studies and by the ability
38 titers but also a Th1 skewed immune response as judged by antibody isotype and cytokine profiles.
40 ablate nearly all hmU-DNA excision activity as judged by assay of tissue extracts from knockout mice
41 xsC and ExsD form self-associated complexes, as judged by bacterial monohybrid and gel filtration exp
42 teine mutants appeared to remain accessible, as judged by binding studies with an antibody against th
45 lation of specific CpG residues and histones as judged by bisulphite genomic sequencing and chromatin
46 per gingival tissue injury than diode laser, as judged by bleeding at surgery, delayed healing, and h
47 sids did not form if this protein was absent as judged by both by ultrastructural analysis of infecte
48 plete loss of multicellular differentiation, as judged by both colony formation and the inability to
49 are primarily pseudopericyclic in character, as judged by both geometrical, energetic and transition
50 levels are achieved during PET/CT sessions, as judged by both motion tracker and verification of spa
52 e thermal stability of the protein variants, as judged by both thermal denaturation and an unseeded i
55 l sites relieved glucose inhibition of SNF1, as judged by catalytic activity, phosphorylation of the
60 y defined, overlapping oligomeric peaks, and as judged by CD these peptides retained significant PPII
62 a3 clasp regions promote integrin activation as judged by cell adhesion, cell spreading, and exposure
63 3.7-fold in the variant as compared with WT as judged by changes in fluorescence of acrylodan-labele
64 ted in 2014, to be suitable for tofu making, as judged by chemical composition and sensory quality of
66 ce the beta-sheet to alpha-helix transition, as judged by circular dichroism (CD), but the degree of
67 ding causes conformational changes in sNUCB1 as judged by circular dichroism and fluorescence spectro
71 , ZEB2) markers and decreased aggressiveness as judged by clonogenic, motility, and invasion assays.
72 t PPARgamma is within the RFX5.CIITA complex as judged by co-immunoprecipitation and DNA affinity pre
74 e in identifying likely regulatory elements, as judged by coincidence with transcription factor bindi
76 ed and prolonged the induction of DNA damage as judged by Comet assays and gammahistone 2AX (gammaH2A
77 o that of the Salmonella typhimurium enzyme, as judged by comparison of the two apoenzymes, large con
79 HT exposure led to reproductive dysfunction, as judged by continuous anestrus, smaller ovaries with a
81 d tumor cells in an antigen-dependent manner as judged by cytokine production and tumor killing, and
82 ls reduces gamma-radiation-induced apoptosis as judged by decreased annexin-V/PI staining, caspase-3
83 dominant factor that drives protein folding as judged by DeltaCp, the change in heat capacity, found
87 ibution were altered in dgt1-1 root tissues, as judged by direct auxin measurements, and the tissue-s
90 es to be prepared at up to 17.5% w/w solids, as judged by dynamic light scattering and transmission e
92 e catalytic efficiency of either polymerase, as judged by either steady-state or pre-steady-state kin
93 ration and organization of myelin membranes, as judged by electron microscopy and quantitative analys
94 n the production of closed capsid structures as judged by electron microscopy and sedimentation metho
95 apoE-/- mice on a high-fat diet develop PAH as judged by elevated right ventricular systolic pressur
97 lations, especially under elevated pressure, as judged by enthalpy criteria and bond length metrics.
98 constituents of the mammalian cell surface, as judged by epifluorescent, confocal, and TIRF microsco
99 n in XLRS only in the severe mutation group, as judged by ERG analysis of the b-wave amplitude and th
100 ipants with suspected or confirmed glaucoma, as judged by experienced clinicians, were tested every 6
101 cers can play a causal role in tumorigenesis as judged by findings with a mouse mammary tumor virus (
102 evels increase, or during fatty acid stress, as judged by flaA expression and evasion of degradation
103 activation leads to loss of gene expression as judged by flow cytometry, Western blot or immunofluor
105 al or greater potency than that of the lead, as judged by fluorescence polarization (IC(50) values we
106 mary epithelial cells caused transformation, as judged by foci formation in culture and tumorigenesis
107 s to correlate fully with the PrP(res) type, as judged by fragment size or glycosylation, the PRNP co
112 The Dm-dNK(+/-)TK2(-/-) mice were normal as judged by growth and behavior during the observation
113 ive genes enhanced the toxicity of alpha-syn as judged by growth defects compared with wild-type cell
114 maintain oxidative phosphorylation function as judged by growth in oxidative phosphorylation-requiri
117 on weight partitioning and endocrine state (as judged by high-molecular-weight [HMW] adiponectin and
118 g in vivo; some ipDNA has quantized lengths, as judged by high-resolution gel electrophoresis of expe
119 ions in a mouse model of CCM1 (Krit1(ECKO) ) as judged by histology and quantitative micro-computed t
120 gly equivalent endocrine cells of each type, as judged by hormone and transcription factor expression
124 The expanded population was fully functional as judged by IFN-gamma production and MHC class I-restri
126 to activated platelets or their releasates, as judged by immunoblotting for phospho-amino acids and
127 ranslocation of p66(Shc) to the mitochondria as judged by immunoblotting using cytosolic and mitochon
128 cross-linked products were typically 50-90%, as judged by immunoblotting, but in no case did the acti
129 levels up to approximately 50% of wild type as judged by immunoblotting, cell surface expression, an
130 ervated regions had remaining Schwann cells, as judged by immunocytochemistry and by electron microsc
133 The stability of mRNAs was also unchanged as judged by in vivo primer extension experiments and by
135 roduced Wnt/beta-catenin pathway activation, as judged by increased activity of a lymphoid enhancer f
136 ) cells was mediated through Notch signaling as judged by increased levels of cleaved Notch1 (NICD1).
137 T-cell response was clearly a Th1 response, as judged by increased levels of gamma interferon (IFN-g
138 ay increased B cell receptor (BCR) signaling as judged by increased levels of phosphorylated Bruton's
139 sporadic and familial human CCM endothelium as judged by increased phosphorylation of myosin light c
140 Rel, RelA, and RelB, which seemed functional as judged by induction of c-Myc and vimentin, products o
141 native NF-kappaB pathway in ABC DLBCL cells, as judged by inhibition of IkappaBalpha phosphorylation.
142 ria in ancient samples are apparently alive, as judged by intact DNA, and fare better than spores.
144 ved F causes conversion to a postfusion form as judged by its "golf tee" morphology in the electron m
145 to the quality of the clusters it uncovers, as judged by its ability to recapitulate protein complex
147 e for UNG to assist antibody diversification as judged by its effect on somatic hypermutation pattern
148 h the enzymatic activation of the apo-enzyme as judged by its esterase activity and ability to cleave
149 2-FHis-labeled PA was biologically inactive, as judged by its inability to deliver a model intracellu
150 ted modifications of the pathogen's surface, as judged by its lipopolysaccharide profile and by its b
151 mmodated in several RNA secondary structures as judged by its minor effect on the thermodynamic stabi
154 omise diagnosis in 1933, and remains popular as judged by its place in the International Classificati
155 mic domain of ADAM10 (A10Cp) is unstructured as judged by its susceptibility to limited trypsin diges
157 significantly affected by the heme rotation, as judged by lack of significant shifts in the nu(Fe-N(H
158 r bundles without provoking hair-cell death, as judged by lack of terminal transferase dUTP nick end
159 We observed that the preferred conformation (as judged by largest cluster size) for each type of RNA
160 evated mammary stem/progenitor cell activity as judged by limiting dilution transplantation experimen
161 Pref-1 null MEF into adipocytes is enhanced, as judged by lipid accumulation and adipocyte marker exp
162 ecreased dramatically by antibody injection, as judged by live analysis of enhanced green fluorescent
163 teins form a complex at the nuclear membrane as judged by live-cell analysis of protein fusions tagge
164 ssion, HK cells failed to support infection, as judged by longer term maintenance of PrP(TSE) accumul
165 ent CD8 T cells were functionally exhausted, as judged by low cytotoxic function and decreased gamma
167 containing up to approximately 20 phosphates as judged by mass spectrometry and Western blotting with
168 e 2,3-diacylglucosamine 1-phosphate product, as judged by mass spectrometry, demonstrating that CcLpx
169 ed hydroxymyristate to RL25 at 42 degrees C, as judged by mass spectrometry, whereas the M290A mutant
170 cted differently in the Foxp2(hum/hum) mice, as judged by measures of dopamine levels, gene expressio
171 esistance to structural conversion in vitro, as judged by measuring changes in antigenicity, the abil
174 n of numerous innate immunity and gut genes, as judged by microarray analysis and in situ hybridizati
176 tion, the conformation of LacY is perturbed, as judged by monoclonal antibody binding studies and by
177 l program (comparable with hog1Delta cells), as judged by mRNA hybridization and microarray analysis.
178 r mass of 116 kDa forms monomers in solution as judged by native gel electrophoresis and has a pI val
179 s decreased their tumor-inhibitory capacity, as judged by neighbor suppression in vitro and accompani
180 ion schedules to measure intestinal immunity as judged by neutralisation of virus and virus-specific
181 pared with the degree of sensitisation (DoS) as judged by nitric acid mass loss testing (ASTM-G67-04)
182 au, although tau was not hyperphosphorylated as judged by occupancy of phosphorylation sites Ser396/S
184 to that previously defined for erythrocytes, as judged by outer leaflet lipid composition; and plasma
185 al and immortal tumors are generated in vivo as judged by p53 mutations and loss of p16(INK4A) expres
187 ges demonstrate that accessible cholesterol, as judged by PFO* or ALO-D4 binding, is not evenly distr
188 onal marker staining, and normal cell growth as judged by phosphohistone H3 staining, cell counting a
190 restored p53-dependent apoptosis in C8146As as judged by poly(ADP-ribose) polymerase cleavage, DNA l
191 2 dominated the antibody response to peanut as judged by prevalence and quantity among a cohort of c
192 inflammatory response from 3T3-L1 adipocytes as judged by prominent induction of the mRNA expression
193 combination of beclomethasone and salmeterol as judged by protection against asthma treatment failure
195 ither mutation abolishes barbed end binding, as judged by pyrene-actin and total internal reflection
198 receptor and impaired signalling downstream, as judged by reduced autophosphorylation of focal adhesi
199 uced chemotactic activity in sputum in COPD, as judged by reduced chemotaxis to the fluid phase of sp
200 orm leads to reversal of the Warburg effect, as judged by reduced lactate production and increased ox
201 senchymal transition was reverted by LOX-PP, as judged by reduced levels of Snail and vimentin; up-re
202 hBGN treatment also improves muscle function as judged by reduced susceptibility to eccentric contrac
203 EAU impaired commitment to the Th17 lineage, as judged by reduction of both RORgammat and IL-17 in CD
204 oxidation (9.0- or 3.8-fold, respectively), as judged by reductive half-reaction studies which show
205 nse, EEG changes, and mitochondrial function as judged by relative changes in tissue NADH concentrati
207 nformational state was similar to wild type, as judged by resistance to proteolysis and interdomain c
209 exhibits a high affinity for reduced flavin, as judged by results obtained with reduced 5-deazaFAD (5
210 eparation and have little or no specificity, as judged by RNA-binding assays and stimulation of their
211 organisational structures in place and are, as judged by routine quality indicators, delivering high
212 o be applicable to polymer-polymer coupling, as judged by SEC, DOSY NMR, and LCxSEC analyses, giving
213 SP fraction isolated from human cancer cells as judged by self-renewal, superior tumor-initiating cap
214 owed kinetics of six-helix bundle formation, as judged by sensitivity to heptad repeat B-derived pept
217 rectly participates in checkpoint signaling, as judged by several dynamic changes, including H2AX pho
219 lar dichroism spectroscopy and were monomers as judged by size-exclusion chromatography (SEC), while
224 was found to be critical for binding to Rev, as judged by surface plasmon resonance and electron micr
225 ein 55 with approximately 1 microM affinity, as judged by surface plasmon resonance and ultracentrifu
229 ld-type virus in inducing DNA fragmentation, as judged by terminal deoxynucleotidyltransferase-mediat
230 ctor in oxygen activation by wild-type nikD, as judged by the 10-75-fold faster rates observed for co
231 imilar to those observed with wild type MDD, as judged by the 2.1 A cocrystal structure of S192A with
232 re relatively selectively permeable to K(+), as judged by the 51-55 mV shifts in reversal potential f
233 droxyurea or aphidicolin, but not etoposide, as judged by the ability of p21CIP1 suppression to mimic
234 However, YjeB regulation of tehA was weak, as judged by the activity of a tehA-lacZ fusion, perhaps
235 cose was directed toward hepatic lipogenesis as judged by the activity, protein levels, and expressio
236 unit export is reduced in Deltaltv1 mutants, as judged by the altered distribution of the 5'-ITS1 rRN
237 (141) were essential for correct cyclization as judged by the antimicrobial activity of the final pro
238 nduced Jag1 expression and Notch2 signaling (as judged by the appearance of activated Notch2 Intracel
239 accuracy of MM-align is significantly higher as judged by the average TM-score of the physically-alig
241 cular reaction that occurs in a single step, as judged by the chirality of the resulting phosphodiest
243 tinence Society; conscious; medically stable as judged by the clinical team and with incontinence cla
245 serted PFO at low and neutral pH was similar as judged by the effect of phospholipid and sterol struc
246 has created a new field only in recent years as judged by the emergence of a giant component of scien
247 preplacodal region appeared to be specified as judged by the expression of Eya2, which marks the com
248 a total of 10,000 neurons are dopaminergic, as judged by the expression of tyrosine hydroxylase (TH)
249 interaction with acyl-carrier protein (ACP), as judged by the failure of the spoT-A413E allele to res
252 t loss of detectable nucleolytic degradation as judged by the growth of mutant T4 and lambda phages a
253 te is detectable during sarcosine oxidation, as judged by the isosbestic spectral course observed for
254 itiate but fail to complete differentiation, as judged by the loss of the pro-differentiation transcr
255 obtained from lungs of AIV-infected animals, as judged by the lower frequency of CD107(+) cells.
256 heless, the process appears to be difficult, as judged by the multiple L substates, with weaker count
257 re detected in the presence of some ligands, as judged by the observed features in the wide angle x-r
258 the initially formed metal-alkyne complexes, as judged by the partial (Ag(+)) or exclusive (Fe(3+)) f
259 ery in mutant IHCs does not develop normally as judged by the persistence of immature features of the
260 lt that cells enter mitosis with damaged DNA as judged by the presence of numerous gamma-H2AX foci on
261 uscle synapses in bgn(-/o) mice are abnormal as judged by the presence of perijunctional folds, incre
262 ssociated genes are transcriptionally active as judged by the presence of RNA polymerase II, dimethyl
263 ith multiple ability and performance metrics as judged by the presence/absence of a statistically sig
264 not significantly affect the binding of PsaC as judged by the rate of charge recombination between P(
265 he recombinant virus was assembly deficient, as judged by the redistribution of viral M and hemagglut
266 s retained through thiol-mediated retention, as judged by the release of adiponectin in response to t
267 is physically reliable in these applications as judged by the size of the fluctuation contribution.
268 imposes a halt on the dislocation reaction, as judged by the stabilization of various dislocation su
269 e relative position of the transition state, as judged by the Tanford beta parameter, beta(T), shifts
270 tioxidant than its water-soluble counterpart as judged by the tau value, it can easily perturb sterol
271 Correlation between AVT responder status as judged by the treating physician and by published res
272 The order of performance of the electrodes as judged by their ability to efficiently transfer elect
273 e N-acetyl-Asp-Glu (NAAG), were transported, as judged by their ability to evoke inward currents.
274 and they retain their tumorigenic potential, as judged by their ability to form metastatic tumors in
275 remained viable after 16 weeks in the cold, as judged by their ability to resume growth following a
276 ro and displayed a shorter lifespan in vivo, as judged by their ability to undergo secondary Valpha-t
277 s features that are single and double layers as judged by their AFM heights of hAFM approximately 1.2
278 to extract accurate kinetic rate constants, as judged by their close agreement with those determined
279 ells - appear to be mechanistically related, as judged by their dependence on vertebrate homologues o
280 lization is impaired in STAT3-deficient mice as judged by their failure to up-regulate circulating ne
282 membrane proteins to chemical denaturation, as judged by their m values, was consistent with that pr
284 nomolar affinity upon mixing in a 1:1 ratio, as judged by thermal melts, circular dichroism, gel-shif
285 gallate and heparin prevent membrane damage as judged by these assays, the other compounds tested ha
286 ely stable across a range of property values as judged by this measure, both in protein-binding studi
287 The relevance of allergic sensitization, as judged by titers of serum IgE antibodies, to the risk
288 exhibited a significant antioxidant activity as judged by total antioxidant activity, DPPH test and r
289 esponse appear to be multigenic and complex, as judged by transcript abundance changes, even in near
290 al IgE responsiveness 3 weeks post-challenge as judged by TSLP receptor levels in 24-hour cultures.
291 ity to detect differentially expressed genes as judged by two popular algorithms, SAM and limma eBaye
292 PMEL isoforms that contain no other proteins as judged by two-dimensional PAGE of metabolically label
293 maturation of BMDCs from both mouse strains as judged by upregulated expression of classical major h
294 ing lymph node (LN) within days of infection as judged by upregulation of the surface markers CD69, c
295 nificant increase in the scientific quality (as judged by using a modified AMSTAR scale) of the SR.
296 n was found to be highly spatially selective as judged by vesicular adhesion to surface patterned sup
297 ecific inhibitor of Src family kinase, PP-2, as judged by Western blot detection of the active form o
300 bound PAH molecules in the AuNP suspensions, as judged by X-ray photoelectron spectroscopy, nuclear m
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