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1 rs were the most altered class by processing as manifested by a 5 to 11-fold increase, notably in the
2 a perturbation in selectin-mediated adhesion as manifested by a 70% reduction in wild-type (WT) neutr
5 spitalisation coincides with recovery of AKI as manifested by a decrease in serum creatinine (sCr).
6 3 restored the connexin-deficient phenotype, as manifested by a dose-dependent reduction in aggregati
7 somes continue to exhibit altered maturation as manifested by a failure to acquire lysosome-associate
8 within the DNA-modified gold nanoparticles, as manifested by a faster decay rate of the excited elec
9 ion of UPF1 led to translational repression, as manifested by a global shift in mRNAs from polysomes
10 ignals and impact on the surface properties, as manifested by a local suppression of ferroelectric di
12 with X-ray photoelectron spectroscopy (XPS), as manifested by a negative shift of the binding energy
13 ited states (excitons) of the quantum wells, as manifested by a new THz frequency- and power-dependen
14 d marked inhibition of in vivo HIV infection as manifested by a profound 70-fold reduction in plasma
15 at markedly inhibit platelet COX-1 activity, as manifested by a profound decline in platelet-derived
16 n tumor cells show resistance to 6-TG damage as manifested by a reduced G(2)-M arrest and decreased a
17 ed a significant delay in mammary maturation as manifested by a reduction of the number and caliber o
18 herapy with nonmetastatic, recurrent disease as manifested by a rising PSA between 0.4 ng/mL and 6.0
19 signaling to reach intracellular substrates, as manifested by a robust increase in phosphorylation of
20 icient to induce BCD cell redifferentiation, as manifested by a significant increase in insulin expre
21 ed in an increased mitoxantrone sensitivity, as manifested by a significantly lower IC(50) value (2.4
22 the entire NC to the copper selenide phase, as manifested by a strongly sigmoidal response in optica
23 y even when they bind the same MHC molecule, as manifested by a unique twisting of the V module relat
24 ad resulted in aberrant planar cell polarity as manifested by abnormalities in the orientation of cel
25 ng cells can be initiated at the cell front, as manifested by actin accumulation at the future leadin
26 fts and resulted in neutrophil infiltration, as manifested by an 18-fold increase in myeloperoxidase
27 emory B cells that were functionally silent, as manifested by an absence of corresponding serum Ab.
29 n lead selenide (PbSe) QD-based solar cells, as manifested by an external quantum efficiency (the spe
30 here kinetic energy exceeds magnetic energy, as manifested by an extremely high frequency of polarity
31 ownregulation of nutrient surplus signaling, as manifested by an increase in the expression and activ
32 n enhances this cortico-cortical connection, as manifested by an increased number of ACC neurons that
33 d characteristics of the malignant phenotype as manifested by anchorage independent cell growth and t
34 n leaves and fruits is that tissue polarity, as manifested by anisotropic growth, is tightly associat
35 tions suggest that humoral immune responses, as manifested by antibody levels, isotype, and antigenic
36 an elevated level of atherogenic particles, as manifested by apoB and LDL particle count, which may
38 SM resulted in an anti-inflammatory response as manifested by attenuated expression of endotoxin-indu
39 mmigration of bone marrow T-cell precursors, as manifested by both an early increase of early thymic
40 R dynamics in the presence of ATP and AcCoA, as manifested by CBP/p300 and SRC-3 dismissal and SAGA a
43 ontrol (Tet34s), induced cell proliferation, as manifested by changes in protein levels of transcript
44 e but decreases the occupancy by RFX1/mSin3A as manifested by chromatin immunoprecipitation assay.
45 task-related local functional connectivity, as manifested by coupling between the phase of alpha osc
46 ression of antigenic diversity in E. maxima, as manifested by cross-strain protection in a series of
47 tion of the mitochondrial apoptotic pathway, as manifested by decreased Akt phosphorylation, increase
48 in kidney ischemia-reperfusion injury (IRI) as manifested by decreased cell growth, generation of to
49 ficient mice had increased oxidative stress, as manifested by decreased NADPH levels and decreased GS
50 duced Ag-specific T cell hyporesponsiveness, as manifested by decreased T cell proliferation and IL-2
51 decreased as HIV-related disease progressed, as manifested by decreasing CD4 cell count and increasin
52 t abnormalities in distal lung morphogenesis as manifested by distinct truncation of the trachea and
53 ificantly prevented naive T cell activation, as manifested by downregulation of CD62L and upregulatio
54 exhibited a decrease in oncogenic signaling, as manifested by downregulation of the transcription fac
55 0 and 30 minutes of VF, stone heart occurred as manifested by dramatic thickening of the myocardium a
56 (LLR), involved the lower right atrium (RA), as manifested by early breakthrough in the lower RA, wav
57 evidence of chronic, low level, inflammation as manifested by elevated circulating levels of acute ph
58 canopy layer urban heat island (UHI) effect, as manifested by elevated near-surface air temperatures
60 ortant role in cell polarization by Cxcl12a, as manifested by elevation of intracellular pH and Rac1
61 ls the binding of neutravidin to the surface as manifested by enhanced scattering over the majority o
63 ability was improved with Fiix-PT monitoring as manifested by fewer tests, fewer dose adjustments, in
64 ness of SR Ca2+ release to activation by ICa as manifested by flattened and broadened voltage depende
65 bility or reduction in sympathetic activity, as manifested by heart rate, plasma norepinephrine or lo
67 onse to a mild psychological stress in rMDD, as manifested by hyperactivation and hyperconnectivity w
68 osystem reprogrammed by H. pylori infection, as manifested by impaired antigen presentation and phago
69 hways/processes associated with liver injury as manifested by increased blood levels of alanine trans
70 t and activation of professional phagocytes, as manifested by increased expression of Fc-gamma recept
71 SC maintenance ability in vitro and in vivo, as manifested by increased HSC mobilization and decrease
72 ce also exhibited increased oxidative stress as manifested by increased hydrogen peroxide production
75 cause of an enhanced mitochondrial function, as manifested by increased oxidative phosphorylation, gl
76 ired Th1 responses against Leishmania major, as manifested by increased parasitemia and more severe l
77 ses in systemic arterial vascular narrowing, as manifested by increased peripheral blood pressure.
78 -green phenotype in perennial grass species, as manifested by increased photosynthetic activities in
79 n the tumor cell membrane for at least 48 h, as manifested by increased recognition by EphA2-specific
80 ell barrier due to chemically induced injury as manifested by increased surface epithelial apoptosis
81 The elderly have reduced humoral immunity, as manifested by increased susceptibility to infections
82 and clearly disinhibited sympathetic arousal as manifested by increased tail piloerection and tail-fl
83 ponsive state similar to endotoxin tolerance as manifested by inhibited TLR2/4-induced expression of
84 inst drug-resistant C. albicans in biofilms, as manifested by inhibition of biofilm formation and by
85 n these cells inhibits their differentiation as manifested by inhibition of calcium or vitamin D-indu
86 ckade also ameliorated CAR T cell exhaustion as manifested by inhibitory receptor reduction, enhanced
87 he shear stress-induced mechanotransduction, as manifested by integrin-Shc association, was abolished
88 isk of disseminated disease at presentation, as manifested by involvement of multiple noncontiguous m
89 xploit a graph-theoretical perspective of GO as manifested by its DAG-structure and the containing hi
90 as such higher-order structural specificity, as manifested by large allosteric changes that activate
91 llar superstructures and smectic mesophases, as manifested by liquefaction and solidification of the
92 ally required in initiating the IRI cascade, as manifested by liver function (serum alanine aminotran
93 ion of axotomised septal cholinergic neurons as manifested by loss of choline acetyltransferase and p
94 of PTEN, which includes the promoter region as manifested by loss-of-heterozygosity of 10q markers.
95 akage from endoplasmic reticulum (ER) stores as manifested by lower cytosolic calcium levels, higher
96 ed by lower post-yield displacement, weaker, as manifested by lower energy and yield and maximal load
97 diet and sex, PKU femora were more brittle, as manifested by lower post-yield displacement, weaker,
98 ically, we find that decreased angiogenesis (as manifested by lower vessel density, decreased hemoglo
99 is revealed due to hexapeptide association, as manifested by lowering of transient interactions betw
101 DR in IECs were highly resistant to colitis, as manifested by marked reductions in clinical colitis s
102 rated cardiac response to pressure overload, as manifested by markedly exacerbated cardiac maladaptiv
103 ssion develop distal renal tubular acidosis, as manifested by metabolic acidosis and alkaline urine p
104 ALPS was identified in 9 unrelated children as manifested by moderate to massive splenomegaly and ly
106 At P11, KO inputs still performed normally, as manifested by normal synaptic attenuation, fidelity,
107 and reduced tubular epithelial cell injury, as manifested by osteopontin expression (5.57 +/- 1.60 v
108 -13 months of age exhibited signs of illness as manifested by paralysis of rear limbs, hunched postur
109 outside-in alphaIIbbeta3 signaling in vitro as manifested by poor spreading on fibrinogen and decrea
110 inflammation and to have more severe disease as manifested by poorer presenting vision and a higher r
111 loped acute physical dependence on morphine, as manifested by precipitated withdrawal signs, such as
112 of DNA-PK), are hypersensitive to high NaCl as manifested by profound inhibition of proliferation, a
113 virulence relative to the wild-type strain, as manifested by prolonged survival, reduced pulmonary f
114 in Akt activity diminish insulin signaling, as manifested by reduced Akt phosphorylation, reduced me
115 tion causes defects in synaptic transmission as manifested by reduced amplitude of both evoked and mi
116 sts that statins induce vascular remodeling, as manifested by reduced atherosclerotic burden without
117 GT and IGT display mitochondrial dysfunction as manifested by reduced ATP production but not with res
118 ess negatively inhibited growth performance, as manifested by reduced biomass (fresh and dry weight)
119 addition, they had less remote organ injury as manifested by reduced pulmonary capillary leakage.
120 ficantly attenuated FFC-induced liver injury as manifested by reduced serum ALT and hepatic TUNEL-pos
121 -Abl and p53 show reduced growth in culture, as manifested by reduction in the rate of proliferation,
122 hibitory signaling in ERK1/2-depleted cells, as manifested by regained cellular ability to undergo gr
128 l epithelial injury, but also to its repair, as manifested by restoration of transepithelial resistan
129 gonal polarization exhibit planar chirality, as manifested by second harmonic generation with strong
131 dephosphorylation of Ser-2808 aggravated CCM as manifested by shortened survival, deteriorated in viv
132 nuation of neurodepression in mice given IA, as manifested by shorter immobility time in the tail sus
134 ducer and activator of transcription pathway as manifested by signal transducer and activator of tran
135 , in turn, activates keratinocytes in vitro, as manifested by signal transducer and activator of tran
137 post-capillary venules are highly glycolytic as manifested by strong expression of lactate dehydrogen
138 tween GO sheets are successfully constructed as manifested by surface-charge-governed ion transport f
139 d resistance to both bacterium and nematode, as manifested by the abolishment of these immune respons
140 e is associated with the intermediate range, as manifested by the appearance in the measured diffract
141 erating points of the primary visual cortex, as manifested by the coherent spontaneous ongoing activi
142 ort effective mimicry of the Bim BH3 domain, as manifested by the crystal structure of an alpha/beta-
146 es are viable for flexible macroelectronics, as manifested by the fabrication of CdS photodetector ar
148 dies of large noncovalent protein complexes, as manifested by the GroEL data where the tetradecamer d
149 ncrease in magnetic anisotropy was observed, as manifested by the increase in the coercive field from
150 kB can lead to increased expression of bcl-x as manifested by the increase in the short form of bcl-x
151 e full apoptotic machinery in this cell type as manifested by the induction of terminal deoxynucleoti
152 ed arachidonate mobilization in these cells, as manifested by the lack of an effect of the iPLA2 anti
155 lternative rather than classical activation, as manifested by the markedly reduced expression of nitr
156 e6] core leads to weaker Fe-Fe interactions, as manifested by the observation of ground states popula
158 nduced apoptosis and enterocyte dysfunction, as manifested by the passage of E. coli across an intact
159 te that the effects of the YlPMR1 disruption as manifested by the phenotypic response depend on the c
160 ice also exhibit defects in B-cell tolerance as manifested by the presence of autoantibodies against
162 the positively charged C moiety of methoxy, as manifested by the pronounced elongation of O-C bond l
163 elerate and amplify host alloresponsiveness, as manifested by the rapid expression of chemokines, cyt
164 tion of Abeta fibril and oligomer formation, as manifested by the recovery of the amide-I band of mon
165 t for efficient pRb C(term) phosphorylation, as manifested by the reduced phosphorylation of a methyl
166 degrees ) and side chains (23-29 degrees ), as manifested by the reduction in the C-H and H-H dipola
167 ed decrease in HSP60 precipitated apoptosis, as manifested by the release of cytochrome c, activation
168 AKI, patients with complete renal recovery, as manifested by the return of the discharge creatinine
169 re cytokines pivotal for B-cell development, as manifested by the severely compromised B-cell develop
170 n interacts strongly with the lipid bilayer, as manifested by the significantly reduced (2)H quadrupo
171 l precordial leads of the electrocardiogram, as manifested by the strain pattern of T-wave inversion
172 position in the ventral cord was disrupted, as manifested by the variable expression pattern of moto
173 er, deformability of the tertiary structure, as manifested by the variance of those same properties,
175 vely tolerized in nonautoimmune BALB/c mice, as manifested by their developmental arrest, follicular
176 ds to increased dynamics of the side chains, as manifested by their disappearance in CP based solid-s
177 ith loss of in vivo activity of the mutants, as manifested by their inability to complement a tempera
178 lectively with D4R silicate framework sites, as manifested by their strong (19)F-(29)Si dipolar coupl
179 le to their highly plastic genome structure, as manifested by tolerance to changing chromosome number
180 , neurotoxicity was observed at these doses, as manifested by transient muscle weakness or paresis, w
181 (1)H NMR provides further evidence of DACT, as manifested by upfield shifts of aromatic protons in t
182 but not US2, is sufficient to induce a UPR, as manifested by upregulation of the ER chaperone Bip an
183 ated candidiasis died of progressive sepsis, as manifested by worsening hypotension, tachycardia, and