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1 the thiol derivatization yield is striking, as reflected by 100% conversion of protein beta-lactoglo
2 al carbon dioxide partial pressure (P(aCO2)) as reflected by 3 to 5 Torr reductions in end-tidal carb
3 , and increased hepatic insulin sensitivity, as reflected by a 2-fold greater suppression of endogeno
4 also increased in the SirT1 ASO treated rats as reflected by a 25% increase in the glucose infusion r
5 d HRAS signaling capacity in cells, however, as reflected by a 4-fold increase in the association of
6 igen-specific T cells to Th1 effector cells, as reflected by a decrease in Ag-stimulated IFN-gamma pr
7 as found to promote receptor desensitization as reflected by a decrease in agonist potency for inhibi
8 re defective in colonization of peanut seeds as reflected by a decrease in conidiation and production
9 n attenuation of chemically induced colitis, as reflected by a decrease in macroscopic and microscopi
10 flammation, and/or hepatocellular ballooning as reflected by a decrease of >/= 2 points in the nonalc
11 ATP concentration were found to be reduced, as reflected by a decrease of A578 values and viable cel
12 as that develops over the course of a trial, as reflected by a drift-rate offset, provides the stimul
13 greater adherence to the Mediterranean diet, as reflected by a higher Alternate Mediterranean Diet Sc
14 to acquire a full-blown GC T(FH) phenotype, as reflected by a higher ratio of GC T(FH)/non-GC CD4(+)
17 to exosite I, exosite II is also disordered, as reflected by a loss of affinity for the gamma'-peptid
19 ffect was more pronounced in Windsor variety as reflected by a lower percentage of ripe berries and s
20 at 1 and 6 months (P = 0.0132; P = 0.0052), as reflected by a lower proportion of patients using ana
21 macro and microscopic anatomy of lymph nodes as reflected by a marked decrease in size of inguinal ly
22 d Sca-1 expression by lin(-) c-kit(+) cells, as reflected by a marked increase in BrdU-negative lin(-
23 resistant to high-fat diet-induced obesity, as reflected by a marked reduction in adipose tissue mas
24 nt improved the accuracy of risk prediction, as reflected by a net reclassification improvement of 22
25 shape of the repertoire was stable over time as reflected by a number of repertoire characteristics,
26 bMTr1 favors the spliced leader 5' sequence, as reflected by a preference for A at position 1 and mod
27 initial androgen-deprivation therapy (ADT), as reflected by a prostate-specific antigen (PSA) level
28 hanges upon iron binding and core formation, as reflected by a quick alteration of its radius of gyra
29 ue macrophages is rapidly suppressed by ART, as reflected by a rapid drop in plasma viral load and a
30 changes in metabolic status during puberty, as reflected by a reduction in Tacr3 (and, to a lesser e
31 y attributable to mitochondrial dysfunction, as reflected by a reduction of approximately 30 percent
32 f tissue injury and fibrosis upon treatment, as reflected by a reduction of collagen deposition to a
33 to a number of factors, but rising incidence as reflected by a rising sex ratio, influenced by gene-e
34 significant impact on the folding structure, as reflected by a significant lowering of the T(m) value
36 ncrease the number of contacts with antigen, as reflected by a tenfold increase in affinity, and one
37 urons and that amyloidogenic APP processing, as reflected by Abeta1-40/42, is associated with mature
38 munication among large-scale brain networks, as reflected by abnormal resting-state functional connec
40 ed to R-loop-driven DNA damage at those loci as reflected by adjacent gamma-H2AX accumulation and ssD
41 2 of gestation showed decreased fetal growth as reflected by all growth parameters at 20-34 weeks, le
43 eurons lacking Klf-9 show delayed maturation as reflected by altered expression of early-phase marker
44 of sleep-deprived mice, and plastic changes as reflected by AMPA receptors phosphorylation are also
45 ability of the activation loop is decreased, as reflected by an approximately 35% increase in B facto
46 known types of antenatal Bartter's syndrome, as reflected by an earlier onset of polyhydramnios and l
47 sociated with an increase in global immunity as reflected by an enhanced delayed type hypersensitivit
48 d enhanced glucocorticoid negative feedback, as reflected by an exaggerated cortisol suppression foll
49 clinical condition and cardiac instability, as reflected by an IH-CHF or IH-CE, are subsequently ass
50 meaningful improvement in physical function, as reflected by an improvement from baseline of at least
51 there was marked renal functional impairment as reflected by an increase in plasma creatinine, associ
52 endent predictor of MR reduction at 6 months as reflected by an increased odds of MR response (odds r
53 kely due to impaired maturation of NK cells, as reflected by an increased ratio in immature to mature
54 ransduction of MSC suppressed chondrogenesis as reflected by an inhibition of Col2a1 and Col10a1 expr
55 pattern of tumor glucose metabolism in LABC, as reflected by analysis of (18)F-FDG rate parameters, c
56 o DDE was related to reduced androgen action as reflected by anogenital distance or penile dimensions
59 ed the avidity of the peptide-MHC for HY TCR as reflected by avidity (K(D)) and dissociation constant
60 ular thrombus formation and improve outcome, as reflected by better motor function, reduced brain les
61 roliferation of lin(-)c-kit(+)Sca-1(+) cells as reflected by BrdU incorporation, phenotypic inversion
62 lar smooth muscle cell (VSMC) proliferation, as reflected by bromodeoxyuridine incorporation, was mar
63 eas the knockout is detrimental to the heart as reflected by cardiac hypertrophy and malfunction at 1
64 c expression of CCHFV NSs induces apoptosis, as reflected by caspase-3/7 activity and cleaved poly(AD
65 minus ends, resulting in failed cytokinesis as reflected by cell wall stubs in leaf epidermal cells.
66 ) recipients, 2C cells did become activated, as reflected by CFSE dilution and CD44 up-regulation.
67 Asymmetric decision threshold adjustments, as reflected by changes in the starting point of evidenc
70 or/oncoprotein, Tax, leads to faulty mitosis as reflected by chromosome aneuploidy, cytokinesis failu
71 of abdominal fat deposit, profibrotic state (as reflected by circulating PICP), reduced insulin sensi
73 ncipal effect of As doping on crystal growth as reflected by considerably reduced average particle si
74 ate matter (PM) with newborn telomere length as reflected by cord blood and placental telomere length
75 sted life expectancy, and cost effectiveness as reflected by costs per quality-adjusted life-year gai
77 renal denervation also reduced inflammation, as reflected by decreased accumulation of total leukocyt
78 54.22, P < .001); faster disease progression as reflected by decreased Mini-Mental State Examination
79 urogranin levels predicted cognitive decline as reflected by decreased Mini-Mental State Examination
80 bules and activate terminal differentiation, as reflected by decreased Osterix, Col1a1, and Dspp expr
81 Patients with FMR have inadequate adaptation as reflected by decreased ratios of leaflet area and are
82 e manifest severe hepatic insulin resistance as reflected by decreased suppression of endogenous gluc
83 survival of mice and inhibited tumor growth, as reflected by decreased tumor volume and prostate-spec
84 CRF dose-dependently disrupted performance as reflected by decreases in correct responding, increas
86 cantly influenced by the metrical structure, as reflected by differences across beat type for both pe
87 rds are processed and remembered differently as reflected by different ERP patterns for the two types
88 assay showed variation in compaction level, as reflected by different FRET efficiency populations, t
89 revealed massive transcriptome reprogramming as reflected by differential expression of approximately
90 r immunity (memory) was severely compromised as reflected by diminished CD8 T-cell recall responses a
91 ment of in vivo tyrosine hydroxylation rate, as reflected by DOPA accumulation following administrati
92 associated with increased LV contractility, as reflected by ejection fraction (p = 0.02), rate of pr
95 en myofibroblasts and cardiomyocytes >5-fold as reflected by elevated connexin 43 and consortin trans
96 ystemic activation of the complement cascade as reflected by elevated levels of the key regulator C3a
97 NF-kappaB pathway are significantly enhanced as reflected by elevated nuclear levels of p65 and RelB,
98 lar macrophage function in ethanol-fed rats, as reflected by endotoxin-stimulated release of TNF-alph
99 ost response during experimental melioidosis as reflected by enhanced bacterial growth at the primary
100 used As(III) as a supplemental energy supply as reflected by enhanced growth and increased cellular l
101 tivity is impaired in a phoQ knockout strain as reflected by enhanced growth of this strain in rice l
102 nse during the first 4 days after admission, as reflected by enhanced inflammation, stronger endothel
103 pared the properties of protein family space as reflected by exhaustive protein family databases and
104 liver enzymes and hepatic insulin resistance as reflected by fasting insulin occur in the early stage
106 otection from Plasmodium falciparum malaria, as reflected by fewer symptomatic cases of malaria, lowe
107 sponse was related to endothelial phenotype, as reflected by flow-mediated dilation and expression of
108 f the (1)C(4) complex to nucleophilic attack as reflected by free energy, C1-O1/O5-C1 bond length elo
109 re unrecognized toxicity to GABAergic cells, as reflected by GAD67 mRNA expression histochemistry, in
110 in expression ratio across the mouse retina, as reflected by ganglion cell responses in vitro, and pr
111 larger and had 32% greater size inequality, as reflected by Gini coefficients, than those with sever
112 pment of allergic sensitization in childhood as reflected by global variations in sensitization patte
113 findings demonstrate that oxidative stress, as reflected by glutathione redox state, increases in th
114 isier neural activity than their classmates, as reflected by greater activity in the absence of audit
115 ed vasodilatory effects, compared with LeTx, as reflected by greater or earlier central venous pressu
117 iabetic complications, and glycemic control, as reflected by HbA1c reduction, results in decreased ri
119 that display a Th1/Th17 phenotypic profile, as reflected by heightened interferon gamma and interleu
120 ramming of human normal prostate fibroblasts as reflected by high levels of alpha-SMA, IL6, and MMP9.
121 tients with well-controlled type 1 diabetes, as reflected by higher brain acetate concentrations and
122 9%; P=0.008), and worse diastolic function, as reflected by higher E/E' ratio (11.7+/-0.2 versus 10.
123 eparanase also impacts exosome protein cargo as reflected by higher levels of syndecan-1, VEGF, and h
124 hat activation of adaptive immune responses, as reflected by higher proportions of circulating CD4(+)
125 hma patients showed small airway dysfunction as reflected by higher R5 -R20 and lower X5 values.
126 meability was increased to a greater extent, as reflected by higher serum levels of lipopolysaccharid
127 DNA alkylating drug compared to WT parasites as reflected by impairment of oocyst formation and sporo
128 ient mice were resistant to ischemic injury, as reflected by improved kidney function, reduced histol
129 the degree of injury to nigrostriatal axons, as reflected by in vitro fiber length density measures,
130 in cultured adult rat ventricular myocytes, as reflected by increased 3H-leucine incorporation (+43%
131 ittent hypoxia induces metabolic dysfunction as reflected by increased body weight and adiposity inde
133 factor deprivation stress-induced apoptosis as reflected by increased DNA fragmentation and caspase
134 acid delivery/triglyceride reesterfication, as reflected by increased expression of CD36, acyl-CoA:d
135 umor microenvironment manifested DNA damage, as reflected by increased expression of gamma-H2AX.
136 osis was exhibited after 6 weeks of feeding, as reflected by increased fecal LPS and bacterial metabo
137 known consequence of hepatic TR activation, as reflected by increased hepatic mitochondrial respirat
138 D183 generally compromise substrate affinity as reflected by increased K(M) values but have less pron
139 o increased amyloidogenic processing of APP, as reflected by increased levels of sAPPbeta and decreas
140 rated development of pneumococcal pneumonia, as reflected by increased levels of viral and bacterial
141 gher lipid and protein oxidation by-products as reflected by increased malondialdehyde and oxidized a
142 resulting from increased hepatic lipogenesis as reflected by increased mRNA levels of fatty acid synt
143 ) are viable, but dark metabolism is altered as reflected by increased nighttime malate, starch, and
144 esponsible for the reduced (18)F-FLT uptake, as reflected by increased pCO(2) and reduced pH and lact
145 ncreased in fructose chow-fed XBP1Delta mice as reflected by increased phosphorylated eIF2alpha, HSPA
147 y occurred exclusively in the two older ages as reflected by increased serum alanine aminotransferase
148 microinjections stimulated 'wanting' to eat, as reflected by increases in intake of palatable sweet c
149 ction, and attention were produced by PACAP, as reflected by increases in reward thresholds, decrease
150 translate the SV2 puncta into synaptic input as reflected by increases in the frequency of spontaneou
151 , certain mutants exhibited reduced toxicity as reflected by induced indoleamine 2,3-dioxygenase (IDO
152 lantation partially improves liver pathology as reflected by inflammatory response, fibrosis, and apo
153 ectively; P < 0.001), as did body cell mass, as reflected by intracellular water (change, -1.0 kg [CI
154 stimulation of the medial forebrain bundle, as reflected by intracranial self-stimulation (ICSS) thr
157 pha2-chimaerin hypersensitive to C1 ligands, as reflected by its enhanced ability to translocate in r
158 nd for the association of Nedd4-2s with Gag, as reflected by its incorporation into virus-like partic
159 y responds to intracellular nitrogen levels, as reflected by its stronger NCR-sensitivity, weaker res
160 n predominantly responds to TorC1 regulation as reflected by its weaker NCR sensitivity, stronger res
162 ell as to protection of normal immune cells, as reflected by lenalidomide studies across multiple typ
163 C stored for 7 days exacerbated liver injury as reflected by liver necrosis and enhanced apoptosis (p
164 re effective than quetiapine and ziprasidone as reflected by longer time until discontinuation for an
165 modulation of vascular smooth muscle cells, as reflected by loss of alpha-smooth muscle cell actin a
167 ization of their V1-V2 and V4-V5 populations as reflected by low levels of total change in HTA patter
168 r levels for N-nitrosamines, HANs, and HAMs, as reflected by lower concentrations of these DBPs measu
170 cient at high salinity than at low salinity, as reflected by lower glucose consumption, lower metabol
171 ed in transgenic compared to wild-type mice, as reflected by lower levels of the specific spectrin br
172 d strongly attenuated systemic inflammation, as reflected by lower plasma cytokine levels, maintenanc
173 otected from fat-induced insulin resistance, as reflected by lower plasma glucose concentrations duri
174 SRT2104 inhibited activation of coagulation, as reflected by lower plasma levels of the prothrombin f
175 d with placebo, reduced disease progression, as reflected by lung function, exercise tolerance, and p
176 speptin-10 elicited a robust GnRH discharge, as reflected by luteinizing hormone secretion, which was
177 ATP and shows aberrant purinergic signaling, as reflected by marked deficiency of the transcription f
178 severely disrupted bone marrow homeostasis, as reflected by marked expansion of hematopoietic stem a
180 d 100% protection against neurodegeneration, as reflected by measurements of KCl-evoked glutamate rel
182 ed interference within transgenes in plants, as reflected by misexpression of the introduced gene and
183 at increased neural efficiency and capacity, as reflected by more "youth-like" brain response pattern
185 ctral inhomogeneity than the ferric species, as reflected by multiple shoulders in the optical absorp
186 vels: (1) the degree of tumor "foreignness," as reflected by mutational burden and expression of vira
187 ure miRNAs, hepatic function was maintained, as reflected by normal blood glucose, albumin, cholester
189 ce of apparently normal cholinergic function as reflected by normal performance of these mice in seve
190 e, limiting biomechanics research potential, as reflected by only few commercial biomechatronics syst
191 ce, without evidence for increased severity, as reflected by percentage of parasitemia, spleen weight
192 nd that retention of a newly acquired skill, as reflected by performance in the second day of practic
193 gen-activated protein kinase (MAPK) activity as reflected by phospho-extracellular signal-regulated k
194 Tsc1 and stimulates the activity of mTORC1, as reflected by phosphorylation of the ribosomal protein
195 activated by endothelin 1 (ET1) (5 nmol/L), as reflected by PKD phosphorylation at Ser744/Ser748 (PK
197 n was associated with induction of apoptosis as reflected by poly(ADP-ribose) polymerase cleavage, ca
198 ka, progressing westward across the caldera, as reflected by post-caldera effusive lava eruptions and
200 photocatalysis can address these challenges, as reflected by recent intensive scientific endeavours t
201 ombination and attenuated bypass replication as reflected by reduced ability to express luciferase fr
202 f neonatal rats to oral E. coli K1 infection as reflected by reduced bacterial intestinal colonizatio
204 400 milliseconds after feedback presentation as reflected by reduced feedback-related negativity (ADH
205 tions were accompanied by structural changes as reflected by reduced fractional anisotropy values, as
206 associated with hepatic insulin resistance, as reflected by reduced insulin suppression of hepatic g
207 hs (n=8), hibernating myocardium was present as reflected by reduced resting LAD flow (0.75+/-0.14 ve
208 and a decrease in endothelial permeability, as reflected by reduction of transendothelial resistance
209 icant reduction in whole-brain MAO-A binding as reflected by reductions in 10 of 11 brain regions.
211 tionally inhibits osteoblast differentiation as reflected by reductions in the expression of osteobla
212 amplitude of the enhancement in sensitivity, as reflected by relative limits of detection or quantita
213 independent changes in substrate utilization as reflected by respiratory quotient, which is increased
214 n be explained by both a synaptic mechanism, as reflected by responses in the subthreshold potential,
216 nduced by cecal ligation and puncture (CLP), as reflected by rising levels of MIP-2 and cytokine-indu
217 rally linked to an attended visual stimulus, as reflected by robust cross-modal spreading-of-attentio
218 er than the HEMORR(2)HAGES and ATRIA scores, as reflected by ROC analysis, reclassification analysis,
219 hat most microbial biomass in these systems, as reflected by rRNA gene abundance, is comprised of org
220 showed the highest GSH, Grx1 and Trx1 levels as reflected by RT-PCR, Western blotting and immunohisto
221 r) and improvement in functional disability, as reflected by scores for the Health Assessment Questio
222 ing was paralleled by behavioral adaptation, as reflected by SD-dependent changes in learning rate.
223 o model 1 in detecting undiagnosed diabetes, as reflected by several significant improvements, includ
224 all immediate over the large delayed reward, as reflected by shorter indifference points) compared to
225 onfigured in many ways during TRV infection, as reflected by significant changes in the levels of sug
226 ar permeability, and coagulation activation, as reflected by significant reductions in lung edema, he
227 n prevent retinal degeneration in rd10 mice, as reflected by significant structural, biochemical, ele
228 of blood-borne lactate in the T1D subjects, as reflected by similar (13)C fractional enrichments in
229 of hydrogels results in intriguing dynamics, as reflected by spontaneous jumping, bouncing, trampolin
233 trongly promoted osteoblast differentiation, as reflected by stimulation of alkaline phosphatase acti
234 wide significant association with longevity, as reflected by survival to ages beyond 90 years, at a n
235 agated to downstream elements of the pathway as reflected by sustained EGF-induced ERK phosphorylatio
236 esponding changes in local sleep regulation, as reflected by SWA, providing evidence for a tight rela
238 ly, there was a decreased rate of apoptosis, as reflected by terminal deoxynucleotidyltransferase-med
239 entry, and assessed the impact of infection as reflected by the ability of HSCs to transfer virus to
240 e on PDHc-E1 and the lipoylamide of PDHc-E2, as reflected by the ability to reductively acetylate the
241 ial rescue was further corroborated in vivo, as reflected by the anergic phenotype of most rescued B
242 increased risk for Alzheimer's disease (AD), as reflected by the Apolipoprotein E epsilon4 (APOE-e4)
244 arameters over 24 months with high accuracy, as reflected by the area under the curve measures: JSW 8
245 on reduced the quality of the muscle tissue, as reflected by the attenuation, revealing increased int
246 the presence of subclinical atherosclerosis, as reflected by the burden of coronary artery calcificat
247 r SGLT3 in coordinating intestinal function, as reflected by the concomitant modulation of Gabsorp an
248 shed course and severity in coinfected mice, as reflected by the degrees of spirochete dissemination
249 g automatic processing of auditory deviance, as reflected by the duration + frequency double deviant
250 ng, trachea, and bladder of exposed animals, as reflected by the elevation of background cII mutant f
251 terparts than products of direct conversion, as reflected by the establishment of target cell-type ge
252 se-dependent, TNF death pathway was blocked, as reflected by the failure of caspase-3 and -7 and poly
253 t the changed spontaneous neuronal activity, as reflected by the fALFF, in these regions may be impli
254 type can control an ecosystem's SOC nature, as reflected by the finding that higher labile C in bamb
256 on of MPPEG increases the efficiency of EAFP as reflected by the generation of hexaPEGylated Hb and t
257 ficacy of new antihyperglycemic medications, as reflected by the guidance of the US Food and Drug Adm
259 conferring vulnerability to opiate addiction as reflected by the high comorbidity of opiate abuse wit
260 ures, a TH17-dominant response was observed, as reflected by the higher amounts of IL-17A and IL-17F
261 d to an upstream shift of the +1 nucleosome, as reflected by the Hmo1 extension and core promoter reg
262 on the glycosylation state of the receptor, as reflected by the inability of overexpression of RPNI
264 ation of routes induced a Th1-type response, as reflected by the induction of stronger antigen-specif
265 he progress of the MR during UHT processing, as reflected by the levels of furosine found in samples.
267 overexpressed Prdx6 reduced oxidative stress as reflected by the lower levels of oxidized phospholipi
269 he strength of N-H...S(gamma) hydrogen bonds as reflected by the midpoint reduction potential, provid
270 layed different levels of proneural activity as reflected by the number and functionality of sense or
271 be the causative agent of multiple sclerosis as reflected by the number of potential triggering mecha
272 cularly dependent on mitochondrial function, as reflected by the observation that diseases of mitocho
273 (so far undefined for the E. coli complex), as reflected by the overall activity of the entire compl
274 erapy reduced the virus-induced inflammation as reflected by the presence of lower amounts of proinfl
275 creased the excitability of the BLA network, as reflected by the pronounced increase of evoked field
277 icular filling pressure response to exercise as reflected by the ratio of peak early diastolic mitral
278 of magnitude higher than any other pathogen--as reflected by the recent emergence of SARS and Influen
279 ndosomes precedes the maturation of the SGs, as reflected by the recruitment of Rab27B, and allows th
280 ts with ADHD showed more simplistic learning as reflected by the reinforcement learning model (exceed
281 their responses to the same sensory stimuli, as reflected by the reliability and temporal precision o
284 ctions of these organisms with the human AM, as reflected by the similarity of gene expression change
285 We found that cerebral glucose metabolism, as reflected by the VTCA, was not significantly differen
286 s lipid metabolism and promotes weight loss, as reflected by the wasting observed in glucagonoma pati
287 n a chiral environment on benzaldehyde lyase as reflected by their circular dichroism signatures.
288 se were fundamentally influenced by P status as reflected by their high correlation with P concentrat
291 ey regulators of mitochondrial redox status (as reflected by thiol/disulfide exchange) by maintaining
294 een behavioral disorders and bowel disorders as reflected by treatment response and effect on behavio
295 , as reflected by the FLI, and dyslipidemia, as reflected by triglycerides, may partly explain the as
296 most potently promote human pDC activation, as reflected by type I IFN release, which was dependent
297 without inhibiting Th17 lineage commitment, as reflected by unaltered RORgammat, STAT3, and FoxP3 ex
298 nt protein induced terminal differentiation, as reflected by upregulation of Fcgamma receptor express
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