ライフサイエンスコーパス: as yet

1 e is no synthesis of these factors available as yet.

2 phenotypes have no physiological explanation as yet.

3 le investigation of their combined potential as yet.

4 ngle-phase multiferroic materials discovered as yet.

5 ver, the technique does have limitations and as yet a general experimental method has not been realiz

6 alternative metabolic pathways involved, but as yet, a direct analysis of the relative redistribution

7 ctions are well established, little is known as yet about the bacterial factors that account for this

8 s that give rise to sound symbolism are not, as yet, altogether clear.

9 whether AVP can affect the skeleton directly as yet another component of the pituitary-bone axis.

10 pulmonary parenchyma has also been described as yet another possible mucosal site of initiation of au

11 ll characterized, very little information is as yet available in Vespidae, although this family repre

12 There has as yet been little examination of one potential substrat

13 ian influenza but no comprehensive study has as yet been reported comparing their innate immunity phe

14 is well documented in metazoans but has not as yet been reported for plant receptor kinases.

15 arget for drug discovery, efforts which have as yet brought little success.

16 erm, and extended therapy options is limited as yet, but as a class they appear to be safe and effect

17 borderline of self and non-self and, through as yet elusive circumstances, mount a Th2 response for a

18 with Th2 pathology; though, the mechanism is as yet elusive.

19 rmed pathogenetic understanding, but no cure as yet exists.

20 rmore, computational dynamo simulations have as yet failed to produce a magnetostrophic dynamo, which

21 However, these avenues have, as yet, failed to define the majority of the heritabilit

22 cal and physiological diversity of ants, but as yet few studies have investigated the genetics of ant

23 However, as yet, few studies provided unequivocal evidence that t

24 for the next wave of GWAS, few studies have as yet focused on rare genetic variants in the study of

25 No treatment exists as yet for FRDA cardiomyopathy.

26 mechanism of TSLP profibrotic effects is not as yet fully understood, although the data suggest that

27 ld be considered a potentially important but as yet generally unrecognized component of the long-term

28 nome sequencing and assembly efforts in this as yet genomically neglected group of crucifer plants.

29 As yet, however, insight into the stoichiometric and ene

30 As yet, human studies have provided little to resolve th

31 ication fork progression by counteracting an as yet ill-defined cohesion "antiestablishment" activity

32 r of exceptions, almost no research activity as yet in developing psychological treatments for people

33 inella chromatophora as a consequence of the as yet incomplete integration of host and chromatophore

34 passive compared with active experience are as yet incompletely understood.

35 rns should be distilled from the diverse and as-yet inconclusive results of existing studies, and mor

36 ding of the photoswitching mechanism, which, as yet, is absent.

37 As yet, it is unknown whether this reduction precedes or

38 lmonary disease overlap syndrome (ACOS), but as yet, it lacks a precise definition.

39 n demonstrated for some tasks, but little is as yet known about the developmental curve of cognitive

40 ent bearing non-walking appendages, features as-yet known in all vicissicaudatans, but aglaspidids.

41 interventional radiotherapy (brachytherapy) as yet lacks any such long-term studies, comparative out

42 t simple triterpenes may have widespread and as yet largely unrecognized functions in plant growth an

43 d micro-plastics are found in the ocean, but as yet little is known about their ultimate fate and the

44 hnologies, existing neural interfaces cannot as yet master the control of prosthetic, paralyzed, or o

45 epartments are bypassing the procedures, and as yet neither the GRC, nor the quality assurance standa

46 rminal center (GC) alters CD22 ligands, with as yet no ascribed biological consequence.

47 ows their ready entry into living cells, but as yet no attempt has been made to assess their toxicity

48 While there is as yet no clear consensus about how best to intervene th

49 people to achieve early diagnosis; there is as yet no definitive role for alternative biomarkers.

50 or adaptation in young and older adults, but as yet no direct comparisons of TDCS effects exist betwe

51 ic acid methyl ester (PC60BM), and there are as yet no established design principles for realizing im

52 prevent the progression of hepatic fibrosis, as yet no evidence has been provided that TGF-beta antag

53 There is as yet no widely replicated assay in which to screen com

54 ble to define prognosis reliably, there are, as yet, no clear diagnostic or response-adjusted paramet

55 t causes significant arterial stiffness, and as yet, no clinical therapy exists to prevent or reverse

56 ant cause of global blindness and there are, as yet, no effective means of screening.

57 coupled hydrogen-bonding networks, there is, as yet, no method that can rigorously calculate the free

58 As yet, no models of these interactions in muscle exist.

59 As yet, no open source software is available for the aut

60 uripotency and multipotency exist, there is, as yet, no single quantitative mark of a cellular sample

61 is fundamental in prokaryotic cells, remains as yet not clearly understood.

62 spectrometry imaging (MSI) has a great, but as yet not fully realized, potential for biomedical diag

63 Since the KRAS oncoprotein is, as yet, not directly druggable, efforts to target KRAS m

64 aspects of BNR yield environmental responses as yet overlooked.

65 ele-specific syndrome causing defects in two as yet pathogenically unrelated functions, reproduction

66 erons and exerts broad antiviral activity by as yet poorly characterized mechanisms.

67 mother centriole-derived basal body (BB) via as yet poorly characterized mechanisms.

68 lence of stationary-phase bacteria, they are as yet poorly characterized.

69 separation of cells based on complicated and as yet poorly understood cell phenotypes.

70 wasting of skeletal muscle and fat tissue by as yet poorly understood mechanisms.

71 control cytosolic trafficking of capsids by as yet poorly understood mechanisms.

72 control the cytosolic movement of capsids by as yet poorly understood mechanisms.

73 d the Parkin ubiquitin-like (Ubl) domain via as yet poorly understood mechanisms.

74 -amyloid beta immunotherapies, including the as yet poorly understood relationship of AD with the imm

75 after menarche, highlighting the central but as yet poorly understood role for sex-restricted anatomi

76 anisms for the repair of telomere damage are as yet poorly understood.

77 t role of lipogenesis in tumor initiation is as yet poorly understood.

78 However, the as-yet poorly characterized contribution of host respons

79 This coordination is as-yet poorly understood, but proteins such as formins a

80 were associated with paediatric IBD, but not as yet replicated.

81 and demonstrate that it corresponds to a not as yet reported inhibitor of Wnt signaling.

82 es performing fine disparity discrimination, as yet the earliest site for this task.

83 Intestinal inflammation is mediated by BFT, as yet the only known virulence factor of ETBF.

84 iagnostic for assessing wound condition, but as yet there are few technological options available to

85 significantly lower allograft survival, but as yet there are no satisfactory therapies for preventio

86 As yet, there are no standardized treatment options for

87 As yet, there has been no investigation into the effects

88 ross-sectional data can be challenging; and, as yet, there have been no longitudinal reports of the t

89 ription; however, no attempts have been made as yet to modulate mammalian transcription factors.

90 function of the biological lens, are unable as yet to provide such an implant with the requisite opt

91 amics they also represent a significant, and as yet unaccounted, marine geohazard.

92 ation densities (10 and 14 plants per m(2)), as yet unachievable in commercial farms with current hyb

93 unodeficiency virus type 1 (HIV-1) is a key, as-yet-unachieved goal of prophylactic HIV-1 vaccine str

94 this issue of the JCI, identify a number of as yet unanswered questions, and discuss some of the the

95 ulate PI metabolism may have significant and as yet unappreciated roles in leukemia.

96 s of the Candidate Phyla Radiation (CPR) and as yet uncharacterized Archaea.

97 om 10(5) to 10(6) biosynthetic gene clusters as yet uncharacterized for potential new therapeutic age

98 NA) intermediates can serve as substrates by as yet uncharacterized integration machinery.

99 protein 2 (NOD2) innate immune receptors by as yet uncharacterized ligands, which are presumed to be

100 aling via isoflavones or through a novel and as yet uncharacterized nonestrogenic pathway.

101 broad range of proteins, it may have other, as yet uncharacterized, downstream effects which could c

102 Wolbachia effectors and point to potential, as yet uncharacterized, links between known phenotypes i

103 n of the iron regulatory hormone hepcidin by as-yet uncharacterized molecular mechanisms.

104 Finally, OsSWEET12, an as-yet uncharacterized SWEET gene with no corresponding

105 ing in single cells of peripheral tissues is as-yet uncharacterized.

106 ct from known virophages and that additional as-yet-uncharacterized virophages are likely present wit

107 However, it is as yet unclear how ROS signaling downstream of receptor

108 major risk factor in multiple sclerosis, via as yet unclear mechanisms.

109 It is as yet unclear what triggers the initial induction of pa

110 brane becomes permeable to these proteins is as yet unclear.

111 host response to influenza infection through as-yet-unclear mechanisms.

112 rial taxa found in the human oral cavity are as yet uncultivated in vitro.

113 acterial candidate phyla radiation (CPR) and as yet uncultivated phyla belonging to the DPANN (Diaphe

114 covered 16S rRNA genes belonging to a novel, as-yet-uncultivated mycoplasma (lineage 'Mnola') in the

115 ome project, now suggests the involvement of as-yet-unculturable and fastidious organisms.

116 robial species, including Filifactor alocis, as-yet-unculturable organisms, and other fastidious orga

117 The as-yet uncultured filamentous bacteria "Candidatus Entot

118 ND3, KCNB1, NOS1AP and HEY2) and others with as yet undefined cardiac function.

119 ng that P3H3 and/or SC65 mutations may cause as yet undefined EDS variants.

120 rom photoreceptors into RPE cells through an as yet undefined mechanism.

121 docycle entry at the G2-M transition as well as yet undefined roles for differentiation regulators (e

122 cellular respiration stimulates SaeRS via an as yet undefined signal molecule(s), resulting in increa

123 chanistic contributions to tumorigenesis are as yet undefined.

124 ion; however, any contribution of B cells is as yet undefined.

125 which new tools or approaches are needed are as yet undefined.

126 d representatives (candidate phyla) and from as-yet undefined lineages.

127 by epithelial-derived Wnt, but also, through as-yet-undefined mechanisms, the surrounding dermal micr

128 lls control the anion conductance, but by an as-yet-undefined route.

129 grS regulation of the phosphatase (yigL) and as-yet-undefined targets also contributed to growth resc

130 This study should help uncover novel and as yet underappreciated functions of vertebrate beta-cat

131 ntrinsic or adaptive brain mechanisms is not as yet understood.

132 combinations, which allowed the inference of as yet undescribed effector functions.

133 rmation about the kinetic isotope effects of as yet undescribed enzymes, thus to make predictions as

134 We also report an as-yet-undescribed mechanism for lipase transport in euk

135 This makes it possible to 1) reveal as yet undetected precursor types in view of exploring t

136 ectron pocket, but whether there is another, as yet, undetected portion to the Fermi surface is unkno

137 Through as yet undetermined mechanisms, circulating and dietary

138 formance that may predict later dementia are as yet undetermined, posterior- versus frontal-type asse

139 oids is bioinspired, and may also inform the as-yet undetermined biosynthesis of several congeners.

140 trolling BLM protein levels, but via another as-yet undetermined mechanism.

141 lncRNAs), and enhancer RNAs (eRNAs), as well as yet undiscovered classes of transcripts.

142 supports the hypothesis that there are many as yet undiscovered hidden allosteric sites and suggests

143 As yet undiscovered particles and interactions might exi

144 CRY stability implicate the existence of an as yet undiscovered regulatory mechanism.

145 icipated that there are numerous additional, as yet undiscovered, direct targets that mediate its glo

146 hell assembly that makes predictions for the as-yet unestablished history of the turtle stem group.

147 This paradox is, as yet, unexplained.

148 f the TH1 type but there are some subtle and as-yet-unexplained differences.

149 nally perturbed during the disease, but with as-yet-unexplained heterogeneity among IBD subtypes and

150 ologue FtsZ and represents an attractive but as yet unexploited target for new antibiotics.

151 This represents an as yet unexploited target to treat bacterial infection a

152 verns the biological effects for most GPCRs, as yet unexplored for the IGF-1R, we sought to investiga

153 cally active microstructures, exploiting the as yet unexplored regime of highly confined liquid cryst

154 We propose PDR1 as an as yet unexplored trait to be investigated for crop prod

155 hese immune responses on host physiology are as yet unexplored, and may have long-term implications i

156 bound on individual nanotubes could lead to, as yet unexplored, spontaneous chemical reactions.

157 g lytic reactivation in epithelial cells are as yet unexplored.

158 oexist with the cochlear ones, a possibility as yet unexplored.

159 scopy and Raman spectroscopy to determine an as-yet unexplored growth mode producing such a shape and

160 corporate decision-making has enormous, but as yet unfulfilled, potential to promote sustainable dev

161 0.1 [C6H14OSi](+) to highlight known as well as yet unidentified ascaroside components in TMS-derivat

162 strated that intracellular replication in an as yet unidentified cell type was essential for dissemin

163 dentified phenolic acids, saponins and other as yet unidentified compounds may contribute to the perc

164 distinct other brain regions, suggestive of as yet unidentified coordinate regulation of brain regio

165 were able to identify candidate proteins for as yet unidentified crucial steps in central metabolisms

166 ed by genetic factors, suggesting a role for as yet unidentified environmental factors.

167 sues for atheroprotection and may have other as yet unidentified functions.

168 probands, likely indicating the existence of as yet unidentified genes.

169 clustering, strongly indicating existence of as yet unidentified localized factors driving apparent d

170 the epistatic interaction of alleles at two as yet unidentified loci.

171 ated in the CHH disease phenotype through an as yet unidentified mechanism.

172 the nucleotide inserted opposite 1-MeA by an as yet unidentified Pol.

173 tends synthesis following nt insertion by an as yet unidentified Pol.

174 , and flgII-28 appears to be perceived by an as yet unidentified receptor in the Solanaceae, although

175 Pol DNA synthesis in vitro, suggestive of an as yet unidentified role of PrimPol in mtDNA metabolism.

176 In addition, the presence of the as yet unidentified silicon phase, Si-VIII and two of ou

177 There are hints of as yet unidentified sources of SL, as well as unknown SL

178 in transport into the brain involves another as yet unidentified transporter molecule.

179 This result suggests that other, as yet unidentified viral proteins encoded by spliced mR

180 ond to T1IFN, indicating that other factors, as yet unidentified, are sufficient to prevent the more

181 but leave open the possibility that another, as yet unidentified, mechanism of desensitization also e

182 -contaminated foodstuffs, and perhaps other, as yet unidentified, routes.

183 an transmission, suggesting that additional, as-yet unidentified amino acid mutations are needed for

184 nt evidence suggests the existence of other, as-yet unidentified APCs also able to prime T cells.

185 to the extracellular space via regulation of as-yet unidentified ATP-releasing channels in an extrace

186 pofuscin may be disease driven, secondary to as-yet unidentified drivers accelerating autophagic path

187 ctivity of a previous sulfur insertion by an as-yet unidentified enzyme.

188 ac, and mysosin IIA, depending instead on an as-yet unidentified GTP exchange factor that activates C

189 S100A9) coordinate Mn(II) in addition to two as-yet unidentified ligands.

190 preBotzinger Complex, and at least one other as-yet unidentified rhythmogenic population.

191 enome-wide nucleotide content, indicating an as-yet unidentified sequence bias for NP association in

192 Hence in the Baltic Sea redoxcline, other, as yet-unidentified factors likely explain the low appar

193 Whether they have other as-yet-unidentified cellular functions is currently unkn

194 suggest that while CXCL10 interacts with an as-yet-unidentified component on the cell surface, PDHc

195 sting the possibility of the existence of an as-yet-unidentified DNAM-1 ligand which may be particula

196 es of lesion bypass and, possibly through an as-yet-unidentified function of the N-terminal tail, fac

197 periodically enter the cilium, suggesting an as-yet-unidentified mechanism that triggers ciliary entr

198 of occlusive thrombi involves additional and as-yet-unidentified mechanisms.

199 menaquinones to outward-facing CprA, via an as-yet-unidentified membrane complex, and potentially an

200 addition to integrin alphaIIbbeta3, another as-yet-unidentified receptor is thought to mediate plate

201 stent with loss of the degron, suggesting an as-yet-unidentified recognition pathway.

202 ng that MC159 prevents IKK activation via an as-yet-unidentified strategy.

203 Additional, as-yet-unidentified substrates are likely to explain the

204 ing that mutations in HCCS, COX7B, and other as-yet-unidentified X-linked gene(s) cause selective los

205 e inhibition of maternal growth by seeds, an as yet unknown activity of the hormone.

206 observed an Ni(2+)-mediated oligomer with an as yet unknown biological function.

207 These results reveal that an as yet unknown cAMP-activated signaling pathway controls

208 were shown to promote IL-17A production with as yet unknown clinical implications.

209 s between the site-specific proteins and the as yet unknown deaminating enzymatic activity.

210 rons in the DVC, Gi, and LPGi; 4) neurons of as yet unknown function in the ventrolateral medulla.

211 SAD6 is a member of the SAD family of as yet unknown function.

212 ency syndromes and vascular integrity, it is as yet unknown how GATA2 functions in the generation of

213 To identify as yet unknown interaction partners of NFAT, we purified

214 points to a residual effect because of many as yet unknown loci that overlap between CAD/MI and CAC.

215 k dedicated stiffness sensors, we rely on an as yet unknown mechanism that generates stiffness percep

216 n in PXE, but there might be an alternative, as yet unknown mechanism, independent of PPi, by which A

217 phagosomes detach from the ER membrane by an as yet unknown mechanism, undergo intracellular transpor

218 1 broadens virus tropism through a distinct, as yet unknown mechanism.

219 YS1 might indirectly affect Wag31 through an as yet unknown mechanism.

220 okes inhibition of the phospholipase C by an as yet unknown mechanism.

221 ion during sepsis, causes lung injury via an as yet unknown mechanism.

222 f Met compared with control seeds through an as yet unknown mechanism.

223 g cell adhesion molecules, but also by other as yet unknown mechanisms.

224 cquisition efficiency and suggest that other as yet unknown motifs affect acquisition efficiency in o

225 th a subset of its non-self S-RNases, and an as yet unknown number of SLFs are thought to collectivel

226 s most probably occur near nesting colonies, as yet unknown or no longer preserved in the immediate s

227 at Amphionides is a larval form, but with an as yet unknown parentage.

228 oduce and secrete these enzymes points to an as yet unknown physiological function.

229 sensory neurons by using a host of known and as yet unknown protein machinery.

230 led in Arabidopsis (Arabidopsis thaliana) by as yet unknown signaling pathways.

231 titute a novel glycoside hydrolase family of as yet unknown specificity.

232 A small molecule natural product of as yet unknown structure, mycofactocin, is thought to be

233 It is as yet unknown whether allogeneic cardiospheres are simi

234 phatic drainage and transport of exosomes is as yet unknown, although the lymphatics play critical ro

235 ng or cross-linking, may require additional, as yet unknown, factors.

236 e additional lifespan to Myotis bats, other, as yet unknown, genetic differences are likely to accoun

237 n multiple targets and each followed unique, as yet unknown, rules governing acceptor-site preference

238 owever, the precise molecular mechanisms are as yet unknown.

239 ism by which REST is regulated in neurons is as yet unknown.

240 e, but the involvement of matrix proteins is as yet unknown.

241 demethylated in Foxp3(+) Treg by mechanisms as yet unknown.

242 ) kinetics during extracellular acidosis are as yet unknown.

243 e, in addition to ferredoxin and NADP(H), is as yet unknown.

244 ia, but its association with skin cancers is as yet unknown.

245 ver, its function in cortical development is as yet unknown.

246 receptor density, compartmentalization, and as-yet unknown binding partners.

247 minin species other than Homo sapiens, at an as-yet unknown date.

248 of pericentriolar material components via an as-yet unknown mechanism.

249 nts may be maintained by new mutations or an as-yet unknown mechanism.

250 otypes contain numerous additional genes for as-yet unknown metabolites.

251 cells, currently designated as DCs, with an as-yet unknown murine counterpart.

252 Here, we hypothesize that an as-yet unknown peptide is involved in the action of angi

253 nce learning requires an understanding of an as-yet unknown relationship between flexibility and brai

254 p in cytohesins but not in BRAGs, and has an as-yet unknown role in EFA6 regulation.

255 xylation of vitamin D, but clearly a second, as-yet unknown, enzyme is another contributor to this im

256 Undaunted by both known and (as yet) unknown challenges, pursuit of myocardial regene

257 minimal risk of resistance development, are, as yet, unknown.

258 the hitherto-known taxa and may represent an as-yet-unknown Acinetobacter species.

259 selective interaction of the compounds with as-yet-unknown cellular target(s) and made possible by t

260 las and gibbons via one or more intermediate as-yet-unknown hosts.

261 ain sensation are separable, suggesting that as-yet-unknown mechanically activated ion channel(s) mus

262 Our data indicate that an as-yet-unknown mechanism of antitermination of transcrip

263 ciation of RAS with blood vessel walls by an as-yet-unknown mechanism, ultimately promoting a 7-fold

264 ategy to avoid immune destruction through an as-yet-unknown mechanism.

265 ow, perhaps just signaling, level through an as-yet-unknown mechanism.

266 nce for a common underlying etiology with an as-yet-unknown mechanism.

267 weetness preferences, suggesting that other, as-yet-unknown mechanisms play a role and that these mec

268 This suggests the operation of as-yet-unknown molecular mechanisms, although the availa

269 s activated to alpha-RP via alpha-R using an as-yet-unknown route to convert DMB to alpha-R and CblS

270 In liver, a signature with an as-yet-unknown underlying mechanism is predominant.

271 Many other important factors may be as yet unmeasured, and adverse outcomes following war-ti

272 ctive cancer vaccines remains an urgent, but as yet unmet, clinical need.

273 es for more advanced disease are urgent and, as yet, unmet clinical needs.

274 toms of antihydrogen to search for possible, as yet unobserved, differences in the physical behaviour

275 xide (.NO) and has been suggested to form an as-yet unobserved bound heme-iron-PN intermediate in the

276 licability for routine disease diagnosis is, as yet, unproven.

277 what to anticipate from the large cohort of as-yet unpublished clinical trials in this arena.

278 also represents a potentially abundant, but as yet unquantified, food source to benthic predators [9

279 ties of domain engineering and potential for as-yet-unrealized nanoscale functional devices.

280 axial functions, such as swallowing, to some as yet unrecognised benefit of reduction in dopaminergic

281 This finding has strong and as yet unrecognized implications for many applications o

282 ferent tissues are endowed with distinct but as yet unrecognized structural, phenotypic, and function

283 that IgG autoantibodies have some important, as yet unrecognized, physiological function.

284 meostasis, and osmotic resistance through an as-yet unrecognized link of HNF1A to sphingolipid homeos

285 Eleven as yet unreported mutations in the laminin-332 genes wer

286 presented in some of their skin biopsies an as yet unreported pathological finding in human VCA, con

287 ecid may inhibit C. trachomatis growth by an as yet unresolved mechanism.

288 nger episodes exert negative effects through as yet unresolved mechanisms.

289 ously thought and include unique lipids with as yet unresolved properties.

290 A critical, and as yet unresolved, question is whether the mucosal bottl

291 ling pathways, the full details of which are as yet unresolved.

292 This study sheds light into the as yet unrevealed action of PFOS on lipid mediators in a

293 neity of cancer has led to a persistent, and as yet unsolved, challenge to develop cures for this dis

294 ng that dyslexia associated genes might play as yet unspecified roles in neuronal physiology.

295 ble for novel computations) is unlikely, and as yet unsupported.

296 full understanding of assembly, which is an as yet untapped potential drug target for this important

297 s reason, we propose that Ric-8 proteins are as yet untested therapeutic targets in which pharmacolog

298 nfant interactions supported the common, but as yet untested, hypothesis that maternal mirroring of i

299 adults' syntactic processing during reading, as yet very little research has focused on syntactic pro

300 a role for miR-132 in neuronal death is not, as yet, well-delineated.