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2 elimination of 5-HT synthesis from the adult ascending 5-HT system by stereotaxic injection of an ade
4 Older individuals compensate for impaired ascending acoustic information by increasing use of cort
5 ir cells shapes maturation of the developing ascending (afferent) auditory system before hearing begi
6 ut may serve a role in the maturation of the ascending (afferent) auditory system by inhibiting spont
10 psule, the white matter (WM) bundle carrying ascending and descending fibers from the OFC and ACC.
12 may depend on reciprocal connections between ascending and descending pathways rather than on unidire
13 pontine and medullary brainstem and includes ascending and descending projections that regulate the E
15 X receptor (FXR) protein levels were seen in ascending and sigmoid colon of PSC patients with corresp
16 (N = 236) collected from terminal ileum and ascending and sigmoid colons of children (median age 13
17 c circulation of BA using ileal and colonic (ascending and sigmoid) biopsies obtained from patients w
20 3.8+/-1.8 mm/m(2); P=0.008) and the proximal ascending aorta (13.8+/-1.9 versus 14.1+/-1.9 mm/m(2); P
21 nd diffuse dilatation of the aortic root and ascending aorta (16.2% versus 7.3%, P<0.001) than women.
22 icantly increased pulse wave velocity in the ascending aorta (3.4 versus 2.3 m/s for PAH and controls
23 stigate whether the pulmonary artery (PA)-to-ascending aorta (Ao) ratio is associated with outcome in
26 ll target-to-background ratio (TBR) from the ascending aorta (primary endpoint) (adalimumab: TBR = 0.
27 ange from start of treatment in TBR from the ascending aorta (TBR = -0.006, 95% CI = -0.049 to 0.038;
28 luded the following: type 1, dilation of the ascending aorta and aortic root; type 2, isolated dilati
29 increased number of elastic lamellae in the ascending aorta and progressive aortic root dilation as
31 ent (defined as pulmonary artery diameter to ascending aorta diameter [PA:A] ratio >1), a marker of p
32 y artery (PA) enlargement defined as a PA to ascending aorta diameter ratio >1 (PA:A>1) is a marker f
33 right/left ventricular and pulmonary artery/ascending aorta diameter ratios were higher (P<0.001, P=
34 than in healthy fetuses (P</=0.001), but the ascending aorta diameter, expressed as z score or millim
35 tubular junction, isolated dilatation of the ascending aorta distal to the sinotubular junction, or d
36 velopment and increased SMC apoptosis in the ascending aorta in response to increased biomechanical f
38 y was to describe blood flow patterns in the ascending aorta of patients with AS and determine their
39 oot reconstruction, or reconstruction of the ascending aorta or aortic arch) with intraoperative blee
40 ndoglin (ENG), and superoxide dismutase 3 in ascending aorta samples from 50 tricuspid and 70 patient
41 nd ENG were analyzed also by Western blot in ascending aorta samples from other 10 tricuspid aortic v
44 insufficiency or a dilated aortic annulus or ascending aorta were at greater risk for reintervention.
46 amount sign of PAH, we hypothesized that the ascending aorta will present signs of apparent stiffness
47 gical repair is optimal for treating type A (ascending aorta) AAS, whereas thoracic endovascular aort
49 aortic valve patients with dilated proximal ascending aorta, ascending aortic area/height ratio was
51 al procedure is needed for dissection of the ascending aorta, given the high mortality (26%-58%) and
53 include increased hemodynamic forces on the ascending aorta, typically due to poorly controlled hype
54 h bicuspid aortic valve and dilated proximal ascending aorta, we sought to assess (1) factors associa
55 d DNA strand breaks in SMCs within the human ascending aorta, which were specifically enriched in SMC
62 ortic root; type 2, isolated dilation of the ascending aorta; and type 3, isolated dilation of the si
65 radient [(brachial PWV/aortic PWV)(0.5)] and ascending aortic and aortic bifurcation diameters to ass
68 n allele died shortly after parturition from ascending aortic aneurysm and spontaneous hemorrhage.
71 ients with dilated proximal ascending aorta, ascending aortic area/height ratio was independently ass
73 ameter of 4.5 to 5.5 cm, 64% had an abnormal ascending aortic area/height ratio, and 70% deaths occur
75 alysis, age did not associate with increased ascending aortic diameter but did associate with increas
77 ifurcation diameters to assess aortic taper (ascending aortic diameter/aortic bifurcation diameter).
78 former NFL athletes had significantly larger ascending aortic diameters (38+/-5 versus 34+/-4 mm; P<0
79 the recommended threshold of aortic root or ascending aortic dilatation that would justify surgical
80 TGF-beta1 bioavailability is associated with ascending aortic dilatation, outflow tract malrotation,
85 ated with bicuspid aortic valves and dilated ascending aortic geometries that are not assessable by c
87 Foxe3 deficiency increased SMC apoptosis and ascending aortic rupture with increased aortic pressure.
88 diatric PAH patients have increased apparent ascending aortic stiffness, which was strongly associate
90 );Ldlr(-/-) mice developed dilatation of the ascending aortic, with greater aneurysmal progression in
92 l forebrain is an important component of the ascending arousal system and may be a key site through w
93 ensory thalamus and is a critical part of an ascending arousal system that controls the firing mode o
94 dal hypothalamus comprises a key node of the ascending arousal system, but the cell types underlying
96 ebrain (BF) is an essential component of the ascending arousal systems and may be a key site through
97 the auditory midbrain, which integrates most ascending auditory information from lower brainstem regi
98 We found that neural SSS emerges within the ascending auditory pathway as a consequence of sharpenin
99 treams are increasingly segregated along the ascending auditory pathway as distinct mutually synchron
100 ring hearing, acoustic signals travel up the ascending auditory pathway from the cochlea to auditory
102 , we investigated SSS in three levels of the ascending auditory pathway with extracellular unit recor
104 regulate IHC activity and maturation of the ascending auditory system in the developing cochlea.
106 isolated intracranial thrombus that impedes ascending blood flow) in the context of acute stroke.
110 te to non-linear firing rate profiles during ascending but not descending phases of contractions.
116 isition of cocaine self-administration using ascending cocaine doses (0.125, 0.25, 0.5, 1.0 mg/kg/inf
118 erry extract by microbiota obtained from the ascending colon and descending colon compartments of a d
119 be divided into three major clusterings: (1) ascending colon and transverse colon, (2) descending col
122 ering all subjects, the percentage change in ascending colon volume rose significantly after CRF.
124 sigmoid colon, or rectum vs appendix, cecum, ascending colon, hepatic flexure, or transverse colon.
125 s defined as any tumor arising in the cecum, ascending colon, hepatic flexure, or transverse colon.
126 sigmoid colon, or rectum vs appendix, cecum, ascending colon, hepatic flexure, or transverse colon.
130 g sensitivities (SE) and specificities (SP) (ascending colon: SE: 1.10%, SP: 91.02; transverse colon:
131 signal intensity (r = 0.88, P = .033 for the ascending colon; r = 0.82, P = .006 for the descending c
132 he ischemically damaged small intestinal and ascending colonic tissue showed a comparably high expres
136 ll intestinal vessel for PM09.960 and in the ascending colonic vessel for accession PM09.812, corresp
138 sets the grounds for further analyses of the ascending connections of the nTTD and the afferents from
139 ns of reticulospinal and commissural primary ascending (CoPA) neurons are among the first myelinated
141 rolled in a two-part study: part 1, a single ascending dose (25-1200 mg), double-blind, randomised, p
142 mly assigned to either Nexvax2 or placebo in ascending dose cohorts (2:1) and in biopsy cohorts (1:1)
147 oups, two double dose groups and four single ascending dose groups challenged with keyhole limpet hem
148 bjects were randomly assigned to four single ascending dose groups, two double dose groups and four s
150 -120 mg IONIS-APO(a)LRx subcutaneously in an ascending-dose design or placebo (in a 3:1 ratio; single
151 r 40 mg IONIS-APO(a)LRx subcutaneously in an ascending-dose design or placebo (in an 8:2 ratio) at da
152 of inclisiran or placebo in either a single-ascending-dose phase (at a dose of 25, 100, 300, 500, or
153 ty, and tolerability at day 30 in the single-ascending-dose phase and day 36 in the multiple-ascendin
154 ending-dose phase and day 36 in the multiple-ascending-dose phase in participants who were randomised
155 se design or placebo (in a 3:1 ratio; single-ascending-dose phase), or multiple doses of 10 mg, 20 mg
159 7288 was evaluated in a randomized, multiple-ascending-dose study in which 40 healthy humans (8 human
160 , double-blind, placebo-controlled, multiple-ascending-dose trial of inclisiran administered as a sub
161 ND In this double-blind, placebo-controlled, ascending-dose trial, patients with heart failure with r
163 ed a single day of buprenorphine followed by ascending doses of oral naltrexone along with clonidine
164 sequential random numbers, to receive either ascending doses of vaccine (60 mug, 120 mug, and 200 mug
165 clusters of sacral VF neurons to deliver the ascending drive required for direct rhythmic activation
166 xt, we recently reported the existence of an ascending excitatory influence from lumbar locomotor CPG
169 ctivity in developing motor circuits and the ascending flow of nociceptive information to the brain,
170 on of the endometrium by pathogenic bacteria ascending from the lower female reproductive tract (FRT)
171 n gain access to the decidua and placenta by ascending from the lower reproductive tract or via hemat
172 found that GABAergic and glycinergic fibers ascending from the pontine reticular formation (PRF) of
173 xpression specifically to glycinergic fibers ascending from the VNLL, allowing for activation of fibe
174 ormation and records from approximately 4000 ascending genealogies to select individuals whose ancest
175 nd suggest that these neurons are part of an ascending glucoregulatory LPBN-->VMN(SF1)-->aBNST neuroc
176 mical evidence shows that the VPMpc receives ascending gustatory inputs from the parabrachial nucleus
177 yotrophic lateral sclerosis, infantile-onset ascending hereditary spastic paraplegia and juvenile pri
178 den (P < .05) but no differences in rates of ascending infection (adjusted RR, 1.24 [95% CI, .71-2.19
180 Identification of factors associated with ascending infection and increased risk of incident infec
181 n the plasmid-encoded Pgp3 are attenuated in ascending infection and no longer are able to induce the
183 t than that of chlamydial pathogenicity with ascending infection in the genital tract, since attenuat
185 tal infection, these measures do not prevent ascending infection that can occur earlier in pregnancy
190 activation of fibers from a single source of ascending input in a way that has not been previously po
194 patient, retrocecal, subhepatic, retrocecal ascending, intraperitoneal abdominal midline localised.
195 ng study, adult patients with HPP received 3 ascending intravenous doses of 5, 10, and 20 mg/kg BPS80
197 and letter abundances; and FALP (Frameshift Ascending Ladder Program) performs a similar task, altho
199 s-sectional aortic diameters were at the mid-ascending level in both groups and were larger in BAV pa
200 rucial for NaCl reabsorption in kidney thick ascending limb (TAL) and drives the urine concentrating
203 and reduced sodium permeability in the thick ascending limb (TAL), leading to a urine concentrating d
204 in basolateral chloride channel in the thick ascending limb and in the aldosterone-sensitive distal n
205 with targeted deletion of PTH1R in the thick ascending limb of Henle (TAL) and in distal convoluted t
206 me, which affect salt transport in the thick ascending limb of Henle's loop and/or the distal convolu
207 ; p-Creb was present in differentiated thick ascending limb of Henle, collecting duct, and stroma; ho
210 al for salt absorption not only by the thick ascending limb, but also by the distal convoluted tubule
213 ic response to diuretics targeting the thick ascending limb, the distal convoluted tubule or the coll
214 C2-mediated sodium transport along the thick ascending limb, while SPAK mainly activates NCC along th
217 ons were markedly reduced in medullary thick ascending limbs isolated from P2Y2 receptor-deficient mi
223 ilitates the local development of grid-scale ascending motion, low-level convergence and the accelera
224 dilations in pupil diameter, suggesting that ascending neuromodulatory systems may govern the transit
227 y may promote the excessive amplification of ascending nociceptive transmission to the mature brain a
228 cted to favor the excessive amplification of ascending nociceptive transmission to the mature brain i
230 increase in oscillatory behavior within the ascending pain pathway occurred during acute noxious sti
231 al increased oscillatory activity within the ascending pain pathway that likely underpins increased t
232 eased oscillatory neural activity within the ascending pain pathway with evidence that these changes
233 fra-slow oscillatory activity throughout the ascending pain pathway, including within the spinal trig
237 cted (iRBCs) with bound platelets during the ascending parasitemia in Plasmodium chabaudi- and Plasmo
240 species richness on the archipelago is in an ascending phase and does not tend towards equilibrium.
241 e monthly sunspots numbers in the succeeding ascending phase of the sunspot activity is found to be 5
243 he SAAs of both Adelta- and C-fibers at the "ascending" phase of microcontractions were significantly
245 is scenario is unclear, partly because their ascending projections have been examined in only one spe
246 We employed a double-label method to map the ascending projections of pruriceptive and nociceptive tr
250 wn to modulate locomotion indirectly through ascending projections to the basal ganglia that project
253 prior studies have reported that the IP has ascending projections to ventral forebrain structures, w
254 ise to descending projections, whereas major ascending projections, including focal projections to ve
256 the geometric mean hs-CRP concentration for ascending quartiles of plasma magnesium were 1.29 (1.06-
258 cortical activating structures including the ascending reticular activating system (ARAS), contributi
259 ugar maple (Acer saccharum), we investigated ascending sap (sugar concentration, delta(13) C, Delta(1
260 e cells (bSCs) are the primary recipients of ascending sensory information via thalamocortical axons
263 xcitability and reduction in transmission of ascending sensory signals via spino-olivo-cerebellar pat
264 ould momentarily enhance the saliency of the ascending sensory stimulus over less urgent, top-down in
266 havioral decisions, analogous to the role of ascending signals from the superior colliculus (SC) in m
273 uggest that, in birds, Ipc axons control the ascending tectal outflow of retinal signals through dire
280 red at 4 anatomically defined locations: the ascending thoracic aorta, descending thoracic aorta, the
281 nts had fusiform enlargement of the root and ascending thoracic aorta, leading to ascending aortic di
282 rysmal degeneration, with 100% penetrance of ascending thoracic aortas, whereas TGFBR2 deletion only
284 s (AMS) affects more than 25% of individuals ascending to 3500 m (11500 ft) and more than 50% of thos
286 documents a rare instance of crocodylomorphs ascending to top-tier predator guilds in the equatorial
287 ina and functions to pattern the activity of ascending touch pathways that underlie tactile perceptio
288 ralateral axonal projections were identified ascending toward higher brain centers, where they formed
289 plasticity, we transected the spinal dorsal ascending tract before or after female rats acquired a n
290 (MLF) and the vestibular neurons through the ascending tract of Deiters (ATD) are a dual system that
294 tal emissions of HMs demonstrate a gradually ascending trend along with the increase of coal consumpt
295 he ventrobasal thalamus, suggesting that the ascending trigeminal pathways in birds and mammals are m
296 ltured kidney epithelial cells, kidney thick ascending tubules, crown cells of the embryonic node, ki
297 Studies have suggested that the fenestrated ascending vasa recta (AVRs) drain the interstitial fluid
299 ementary endothelial signalling pathways for ascending vasodilatation ensure increased oxygen deliver
300 esized that the signalling events underlying ascending vasodilatation variy with the intensity and du
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