ライフサイエンスコーパス: ascending aorta

1 l dissection (flow in the false lumen of the ascending aorta).

2 oma (5 with and 5 without involvement of the ascending aorta).

3 tween the pulmonary arterial truncus and the ascending aorta).

4 infusion induces aneurysmal pathology in the ascending aorta.

5 biting Ang II-induced SMC hyperplasia of the ascending aorta.

6 ns, with the exception of hyperplasia of the ascending aorta.

7 ion of aortic valve malformation and dilated ascending aorta.

8 y bypass grafts, and 5 (16%) had a porcelain ascending aorta.

9 or diffuse dilatation of the aortic root and ascending aorta.

10 maintaining the structural integrity of the ascending aorta.

11 vious operation involving a cardiac valve or ascending aorta.

12 ) was induced in felines by constricting the ascending aorta.

13 r the left coronary artery, aortic root, and ascending aorta.

14 ng confocal microscopy and normalized to the ascending aorta.

15 ssure overload caused by constriction of the ascending aorta.

16 und to have severe AAD in the aortic arch or ascending aorta.

17 osclerotic lesion size was quantified in the ascending aorta.

18 60 and 100 secs after cross-clamping of the ascending aorta.

19 percent) had aortic dissection involving the ascending aorta.

20 problems of dilatation and dissection of the ascending aorta.

21 the tip of the tubing was positioned in the ascending aorta.

22 mice to study vascular calcification in the ascending aorta.

23 t transplant consisting of a donor heart and ascending aorta.

24 m after composite aortic graft repair of the ascending aorta.

25 n and peak systolic wall shear stress in the ascending aorta.

26 egion behind the sternum and anterior to the ascending aorta.

27 sity and impaired SMC differentiation in the ascending aorta.

28 s and flow eccentricity were assessed in the ascending aorta.

29 part, because of spontaneous rupture of the ascending aorta.

30 analyzed 74 patients with dissection of the ascending aorta.

31 ulus and produces a force that stretches the ascending aorta.

32 olumes of interest (VOIs) defined within the ascending aorta.

33 e in diameter that is most pronounced in the ascending aorta.

34 3.8+/-1.8 mm/m(2); P=0.008) and the proximal ascending aorta (13.8+/-1.9 versus 14.1+/-1.9 mm/m(2); P

35 nd diffuse dilatation of the aortic root and ascending aorta (16.2% versus 7.3%, P<0.001) than women.

36 helical flow in the ascending aorta, larger ascending aortas (18.3+/-3.3 versus 15.2+/-2.2 mm/m(2);

37 579); main pulmonary artery, 261 (169, 353); ascending aorta, 191 (121, 261); superior vena cava, 137

38 n of the EAC was monitored by (1) TEE of the ascending aorta, (2) pulsed-wave Doppler of the right ca

39 icantly increased pulse wave velocity in the ascending aorta (3.4 versus 2.3 m/s for PAH and controls

40 duced by the dissection were observed in the ascending aorta (40.1 [36.6; 45.3] mm vs. 52.9 [46.1; 58

41 follows: main pulmonary artery, 56 (44, 68); ascending aorta, 41 (29, 53); superior vena cava, 29 (15

42 ion increased lesion size 2-fold in both the ascending aorta (50 642 +/- 12 515 versus 112 399 +/- 13

43 ood flow was analyzed to investigate altered ascending aorta (AAo) hemodynamics in bicuspid aortic va

44 gical repair is optimal for treating type A (ascending aorta) AAS, whereas thoracic endovascular aort

45 termined using the augmentation index in the ascending aorta (AIaa) and distal descending aorta (AIda

46 ment of a perivascular flow probe around the ascending aorta and a pressure volume conductance cathet

47 aneurysm, coarctation, and dissection of the ascending aorta and aortic arch are often associated con

48 o the smooth muscle layer of the wall of the ascending aorta and aortic arch.

49 luded the following: type 1, dilation of the ascending aorta and aortic root; type 2, isolated dilati

50 Contemporary outcomes for ascending aorta and arch replacement in North America ar

51 Current outcomes for ascending aorta and arch replacement in North America ar

52 y was to characterize operative outcomes for ascending aorta and arch replacement on a national scale

53 ith adalimumab compared with controls in the ascending aorta and carotids.

54 Aortic dissections originating in the ascending aorta and descending aorta have been classifie

55 d with systolic pressure augmentation in the ascending aorta and has the potential to worsen afterloa

56 acute aortic dissection (TB-AAD) spares the ascending aorta and is optimally managed with medical th

57 eurysms that is particularly confined to the ascending aorta and its branches.

58 hat can lead to narrowing or blockage of the ascending aorta and other arterial vessels.

59 increased number of elastic lamellae in the ascending aorta and progressive aortic root dilation as

60 ed implantation technique in which the donor ascending aorta and pulmonary artery are sutured end-to-

61 sac as it was remodeled into the base of the ascending aorta and pulmonary trunk, the distal truncus

62 size was quantified in 2 vascular beds: the ascending aorta and the aortic arch.

63 Through a small thoracotomy, the ascending aorta and the main pulmonary artery were occlu

64 In patients with a dilated proximal ascending aorta and trileaflet aortic valve, we aimed to

65 type A aortic dissections (which involve the ascending aorta) and 15 patients with acute type B aorti

66 nd beta-stiffness index) at the aortic root, ascending aorta, and descending aorta.

67 may explain these loading conditions in the ascending aorta, and systolic pressure augmentation may

68 ated even more monocytes in the aortic root, ascending aorta, and thoracic aorta after both chow (503

69 kedly reduced plaque size in aortic sinuses, ascending aortas, and brachiocephalic arteries.

70 ortic root; type 2, isolated dilation of the ascending aorta; and type 3, isolated dilation of the si

71 stigate whether the pulmonary artery (PA)-to-ascending aorta (Ao) ratio is associated with outcome in

72 ity in diameters of the sinuses of Valsalva, ascending aorta, aortic arch, and descending aorta, resp

73 Extensive aortic aneurysms (ascending aorta, aortic arch, and descending or thoracoa

74 aF uptake was quantified at the level of the ascending aorta, aortic arch, descending thoracic aorta,

75 his finding was observed at the level of the ascending aorta, aortic arch, descending thoracic aorta,

76 d for extensive aneurysms involving both the ascending aorta/aortic arch and the descending thoracic

77 Calcification of the ascending aorta, arch, carotid, and coronary arteries wa

78 Aneurysms and dissections affecting the ascending aorta are associated primarily with degenerati

79 Methods other than size measurement of the ascending aorta are needed to identify patients at risk

80 required reoperation on the aortic valve or ascending aorta, as did 49 in the GV group.

81 Replacement of the ascending aorta (Asc Ao) at the time of aortic valve rep

82 aortic valve patients with dilated proximal ascending aorta, ascending aortic area/height ratio was

83 ation was measured in the carotid artery and ascending aorta at baseline and week 15, by (18)F-fluoro

84 the mPA and transverse axial diameter of the ascending aorta at the level of the bifurcation of the r

85 Management of the ascending aorta at the time of aortic valve replacement

86 , left ventricular dysfunction (p < 0.0001), ascending aorta atherosclerosis (p < 0.0001), hypertensi

87 logic events were: hypertension (p = 0.009), ascending aorta atherosclerosis (p = 0.011) and diabetes

88 operative epiaortic ultrasound to assess for ascending aorta atherosclerosis was performed in all pat

89 In the patient population with dilated ascending aorta, both peak TKE and total TKEsys were sig

90 for identification of atherosclerosis of the ascending aorta, but both ultrasound techniques are supe

91 rn predominantly affecting the distal aorta (ascending aorta by -22%, proximal descending aorta by -2

92 e performed, including multiple views of the ascending aorta by aortography.

93 cusp near its free margin to the wall of the ascending aorta cephalad to the sinotubular junction.

94 inhibitor of differentiation 3 (Id3) in the ascending aorta compared to all other regions.

95 rior/rightward LA roof, directly beneath the ascending aorta (confirmed by merging the CT image and m

96 Individuals with a dilated ascending aorta defined as aortic size index > 2.0 cm/m2

97 ortic clamp," EAC) used for occlusion of the ascending aorta, delivery of cardioplegia, aortic root v

98 ry artery diameter (mPA) and ratio of mPA to ascending aorta diameter (ratio PA) derived from chest C

99 ent (defined as pulmonary artery diameter to ascending aorta diameter [PA:A] ratio >1), a marker of p

100 y artery (PA) enlargement defined as a PA to ascending aorta diameter ratio >1 (PA:A>1) is a marker f

101 The CPI40, main pulmonary artery diameter to ascending aorta diameter ratio (MPAD/AAD), and an extent

102 right/left ventricular and pulmonary artery/ascending aorta diameter ratios were higher (P<0.001, P=

103 than in healthy fetuses (P</=0.001), but the ascending aorta diameter, expressed as z score or millim

104 the consequence of a condition affecting the ascending aorta: dissection, 28 patients (19%); the Marf

105 tubular junction, isolated dilatation of the ascending aorta distal to the sinotubular junction, or d

106 ange, 1-55; 17% <18 years of age; 60% male), ascending aorta distensibility was reduced in comparison

107 A transit-time flow probe was placed on the ascending aorta during cardiac surgery in 24 patients wi

108 ure overload (induced by constriction of the ascending aorta for 7 days in rats) resulted in cardiac

109 Segments of the ascending aorta from the native and allograft hearts fro

110 METHODS AND Ascending aortas from patients with dilated aortopathy w

111 al procedure is needed for dissection of the ascending aorta, given the high mortality (26%-58%) and

112 Baseline ascending aorta > or =40 mm independently predicted surg

113 In 8 dogs in which gradual stenosis of the ascending aorta had caused severe left ventricular (LV)

114 A greater tubular ascending aorta (hazard ratio [HR] 5.6, 95% confidence i

115 = 0.002), and concomitant replacement of the ascending aorta (hazard ratio: 7.7; p = 0.0003).

116 icuspid valves induced significantly altered ascending aorta hemodynamics compared with age- and size

117 ons as well as the elastic properties of the ascending aorta in 48 FDRs with morphologically normal t

118 A graft was present in the ascending aorta in 93 patients, in the descending aorta

119 observed dose-dependent spread to the heart/ascending aorta in animals infected with C. pneumoniae.

120 s observed exclusively in the Fbn1(C1039G/+) ascending aorta in association with repressed elastin mR

121 rwent primary AVR without replacement of the ascending aorta in New York State between 1995 and 2010

122 d in the detection of atherosclerosis of the ascending aorta in patients undergoing cardiac surgery.

123 racellular matrix (ECM) dysregulation in the ascending aorta in patients with bicuspid aortic valves

124 velopment and increased SMC apoptosis in the ascending aorta in response to increased biomechanical f

125 annulus, sinuses, sinotubular junction, and ascending aorta in the BAV group, with aortic root dilat

126 a patient who developed a dissection of the ascending aorta in the setting of IgG4-related systemic

127 Atherosclerosis of the ascending aorta is a major risk factor for perioperative

128 to determine whether atherosclerosis of the ascending aorta is a predictor of long-term neurologic e

129 Atherosclerosis of the ascending aorta is an independent predictor of long-term

130 minimized, and manipulation of the diseased ascending aorta is avoided.

131 al hematoma concerns its management when the ascending aorta is involved.

132 ly abnormal right-handed helical flow in the ascending aorta, larger ascending aortas (18.3+/-3.3 ver

133 The ascending aorta length increased most, with age leading

134 cerebral atheroembolism, an atherosclerotic ascending aorta may be a marker of generalized atheroscl

135 Aneurysms were located in the ascending aorta (n = 2, 6%), descending thoracic aorta (

136 n both in patients with a BAV with a dilated ascending aorta (n = 6) and in those with a normal ascen

137 ing aorta (n = 6) and in those with a normal ascending aorta (n = 9), was seen in the absence of aort

138 oups: 1, sham-operated (n=15); 2, banding of ascending aorta (n=22); 3, banding+clenbuterol (n=18); a

139 Five deaths and 2 dissections of the ascending aorta occurred during follow-up.

140 helical flow was seen at peak systole in the ascending aorta of 15 of 20 patients with a BAV but in n

141 lation and elastic fiber degeneration in the ascending aorta of BAV patients, implicating valve-relat

142 ased regional wall shear stress (WSS) in the ascending aorta of BAV patients.

143 thesis/deposition genes, is increased in the ascending aorta of Marfan (Fbn1(C1039G/+)) mice.

144 showed abnormal helical systolic flow in the ascending aorta of patients with a BAV, including those

145 y was to describe blood flow patterns in the ascending aorta of patients with AS and determine their

146 s not expressed in the coronary arteries and ascending aorta of the cardiac allograft from the estrad

147 r IGF-I protein in the coronary arteries and ascending aorta of the cardiac allograft from the placeb

148 sis), and 59% (elastic fragmentation) in the ascending aorta of the TOF group.

149 n the aorta, principally the aortic root and ascending aorta, of 10-wk-old ApoE(-/-) compared with 10

150 lactic replacement of the aortic root and/or ascending aorta once the aortic diameter exceeds 5.5 cm.

151 ry artery disease, one ruptured ulcer of the ascending aorta, one ruptured aneurysm of the right subc

152 hage, rupture of either the pulmonary trunk, ascending aorta or a bronchial artery, or vasospastic ce

153 oot reconstruction, or reconstruction of the ascending aorta or aortic arch) with intraoperative blee

154 Patients were cannulated via the ascending aorta or common femoral artery with bicaval ve

155 e descending aorta died versus 14% with only ascending aorta or hemiarch replacement.

156 nderestimation was more marked in the distal ascending aorta (p < 0.0001).

157 nulus (p < 0.0002), aortic root (p < 0.003), ascending aorta (p < 0.008) and left ventricular long-ax

158 rosis (p = 0.001) and atherosclerosis of the ascending aorta (p = 0.03) were independently associated

159 NFL athletes still had significantly larger ascending aortas (P<0.0001).

160 Medial abnormalities in ascending aorta, paracoarctation aorta, truncus arterios

161 Intraoperative biopsies from ascending aorta, paracoarctation aorta, truncus arterios

162 nic obstructive pulmonary disease, calcified ascending aorta, peripheral arterial disease, renal fail

163 A greater tubular ascending aorta, presence of mitral regurgitation, reduc

164 ll target-to-background ratio (TBR) from the ascending aorta (primary endpoint) (adalimumab: TBR = 0.

165 ls then underwent thoracotomy and banding of ascending aorta producing left ventricular failure and c

166 occurs at anterior/rightward roof, where the ascending aorta provides resistance to the LA.

167 tion, ventricular septal defect closure, and ascending aorta replacement in 1 patient each.

168 ndoglin (ENG), and superoxide dismutase 3 in ascending aorta samples from 50 tricuspid and 70 patient

169 nd ENG were analyzed also by Western blot in ascending aorta samples from other 10 tricuspid aortic v

170 ers; therefore, early elective repair of the ascending aorta should be considered.

171 e is debate concerning whether an aneurysmal ascending aorta should be replaced when associated with

172 ultrasound and biplane TEE, palpation of the ascending aorta significantly underestimated the presenc

173 Dilation is most prominent at the ascending aorta, similar to the pattern seen in nonsyndr

174 ose without AoD (both p < 0.05), whereas the ascending aorta size was similar.

175 Lower ascending aorta strain (P=0.02) was associated with a hi

176 Diseases affecting the ascending aorta, such as thoracic aortic aneurysms and t

177 ted status was determined by dilation of the ascending aorta, surgical repair of an aneurysm or disse

178 ange from start of treatment in TBR from the ascending aorta (TBR = -0.006, 95% CI = -0.049 to 0.038;

179 sociated with mechanical manipulation of the ascending aorta that occasionally leads to type A aortic

180 Most of the ascending aortas that had dissected initially had a diam

181 s and induced atherosclerosis lesions in the ascending aorta (the cross-section area of 156514+/-5740

182 tromagnetic flow probe was placed around the ascending aorta through a right thoracotomy for measurem

183 y systemic arterial pressure waveforms, from ascending aorta to femoral artery, were transduced and a

184 minutes after release of constriction of the ascending aorta to increase left ventricular (LV) systol

185 io of FDG uptake in the arterial wall of the ascending aorta to venous background as the target-to-ba

186 ive ascending aortic replacement for dilated ascending aortas to prevent aortic dissection.

187 (80%) of five patients with hematoma of the ascending aorta (type A) and in two (12%) of 17 patients

188 Involvement of the ascending aorta (type A) was more frequent in group 2 (8

189 include increased hemodynamic forces on the ascending aorta, typically due to poorly controlled hype

190 Ang II infusion promotes aneurysms in the ascending aorta via stimulation of AT(1a) receptors that

191 The observation of right-anterior ascending aorta wall/jet impingement in right-left BAV p

192 Atherosclerosis of the ascending aorta was assessed intraoperatively (epiaortic

193 eserved and supracoronary replacement of the ascending aorta was done.

194 root at the sinotubular junction and at the ascending aorta was indexed to the left ventricle.

195 The ascending aorta was invested by lacZ-positive cells whil

196 h bicuspid aortic valve and dilated proximal ascending aorta, we sought to assess (1) factors associa

197 des, dyslipidemia and atherosclerosis in the ascending aorta were abolished, whereas lesions in the d

198 findings were obtained when tissues from the ascending aorta were analyzed.

199 insufficiency or a dilated aortic annulus or ascending aorta were at greater risk for reintervention.

200 ntensity curves for the pulmonary artery and ascending aorta were derived from the MR angiography ima

201 entation and transmural medial breaks of the ascending aorta were observed with continued Ang II infu

202 r and peak systolic wall shear stress in the ascending aorta were quantified.

203 controls, WSS patterns in the right-left BAV ascending aorta were significantly elevated, independent

204 Intimal surface areas of ascending aortas were measured to quantify ascending AAs

205 rome undergoing resection of aneurysm of the ascending aorta) were operated on using this technique.

206 ing ARB therapy (P<0.05), whereas the distal ascending aorta, which does not normally become dilated

207 carcinoma and a spindle-cell sarcoma of the ascending aorta, which had metastasized to the spleen.

208 d DNA strand breaks in SMCs within the human ascending aorta, which were specifically enriched in SMC

209 amount sign of PAH, we hypothesized that the ascending aorta will present signs of apparent stiffness

210 ents underwent prospective evaluation of the ascending aorta with two ultrasound techniques-epiaortic

211 ic Surgeons Database for patients undergoing ascending aorta (with or without root) with or without a

212 57BL/6J mice promoted rapid expansion of the ascending aorta, with significant increases within 5 day