ライフサイエンスコーパス: aspartic proteinase

1 brain beta-secretase is a new membrane-bound aspartic proteinase.

2 prophytepsin, a zymogen of a barley vacuolar aspartic proteinase.

3 mproved recombinant model for this important aspartic proteinase.

4 e proteinases, but not by those for MMPs and aspartic proteinases.

5 falciparum, HIV-1 protease, and the secreted aspartic proteinase 2 (SAP-2) from Candida albicans; the

6 IA(3), the endogenous inhibitor of yeast aspartic proteinase A (YPrA), is an unstructured protein

7 rves as an endogenous inhibitor of the yeast aspartic proteinase A (YPrA).

8 ams, based on comparisons of PAG and related aspartic proteinase amino acid sequences, suggests that

9 and PfHAP (a histoaspartic proteinase) are 4 aspartic proteinases among 10 encoded in the Plasmodium

10 ent proposals for the catalytic mechanism of aspartic proteinases are largely based on X-ray structur

11 lications for the catalytic mechanism of the aspartic proteinases as it is consistent with the propos

12 These data suggest multiple roles for aspartic proteinases besides those proposed in seeds.

13 The classic aspartic proteinase bilobal structure and domain topolog

14 w to studying the catalytic mechanism of the aspartic proteinases by locating the active site protons

15 The aspartic proteinase cathepsin E (CatE) has been implicat

16 s Endothia parasitica and is a member of the aspartic proteinase class of enzymes.

17 is bound to cytochrome P450, DSA4 may be an aspartic proteinase, DSA5 is as yet unidentified, DSA6 i

18 can be collected from crystals of the fungal aspartic proteinase endothiapepsin bound to a transition

19 d to investigate the transition state of the aspartic proteinase endothiapepsin.

20 yeast Ddi1 protein as the only member of the aspartic proteinase family in Leishmania parasites, and

21 nses of 60 to 80%) and shows homology to the aspartic proteinase family of enzymes.

22 late species and are inactive members of the aspartic proteinase family, can also bind ovUS-1 and may

23 dy of pepstatin binding to plasmepsin II, an aspartic proteinase found in Plasmodium falciparum, usin

24 ures of glycosylated native proteinase A, an aspartic proteinase found in the vacuole of Saccharomyce

25 The crystal structure of the secreted aspartic proteinase from Candida tropicalis yeast (SAPT)

26 is early stage of its characterization, this aspartic proteinase fulfils many of the key criteria nec

27 panel of inhibitors of serine, cysteine, and aspartic proteinases had no effect, suggesting that aggr

28 has identified three different typical plant aspartic proteinases in the genome of Arabidopsis thalia

29 e has great structural homology to mammalian aspartic proteinases including human renin and we have u

30 tor was synthesized by linking the microbial aspartic proteinase inhibitor pepstatin to mannosylated

31 , aligns with the first 4 amino acids of the aspartic proteinase inhibitor pepstatin.

32 e- and quadruple-PM KOs to six different HIV aspartic proteinase inhibitors was comparable to that of

33 f susceptible peptide bonds in the design of aspartic proteinase inhibitors.

34 Saccharopepsin is a vacuolar aspartic proteinase involved in activation of a number o

35 ed cysteine proteinases, serine proteinases, aspartic proteinases, metallo proteinases, and aggressiv

36 ve been identified only very recently as new aspartic proteinases of the pepsin family.

37 be a competitive inhibitor of a subgroup of aspartic proteinases: pepsin, gastricsin and cathepsin E

38 xons is identical to that of other mammalian aspartic proteinase precursors, including pepsinogen.

39 Sequencing of the aspartic proteinase protein purified from Arabidopsis se

40 rulence factors of C. albicans, the secreted aspartic proteinases (Saps).

41 Cathepsin E is an aspartic proteinase that has been implicated in Ag proce

42 Cathepsin E is an intracellular aspartic proteinase that is considered to have a number

43 major laboratories claiming a transmembrane aspartic proteinase to be the long sought after beta-sec

44 OvUS-1 is the first specific inhibitor of aspartic proteinases to be identified in vertebrates and

45 ts acyclic analogue with penicillopepsin, an aspartic proteinase, to study the effect of conformation

46 Aspartic proteinases, which include HIV-1 proteinase, fu

47 structure of Bla g 2 was similar to that of aspartic proteinases with a well-defined binding pocket.