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2 400 million reads were generated and de novo assembled into 107,744 unigenes, with a mean length of 1
4 ollowing filtering, these reads were de novo assembled into 36 529 transcript sequences that were ann
5 oscale material that can be designed to self-assemble into 3D structures that are fully determined by
8 verned by extracellular matrix proteins that assemble into a 3D organic matrix directing the depositi
10 many copies of the capsid protein (CA) self-assemble into a capsid shell to enclose the viral RNA.
12 amide sequence was designed to fold and self-assemble into a double helical host having a cylindrical
13 omers, such as compound 1, can spontaneously assemble into a double helix without the need for a cova
14 hich are intermediate filament proteins that assemble into a filamentous meshwork, bridging the nucle
15 y high volume fraction (varphi), dynamically assemble into a fully percolated 3D network within high-
18 rmed rapidly at the liquid/liquid interface, assemble into a monolayer, and, when jammed, offer a rob
20 together with the cytoskeletal protein talin assemble into a signaling complex upon E-cadherin loss.
28 heir unique topologies and abilities to self-assemble into a variety of extended and aggregated struc
29 sin led to a [2]rotaxane structure that self-assembled into a [3]catenane and [4]catenanes at room te
31 sion, FVIIa Q64C and sTF G109C spontaneously assembled into a covalent complex with functional proper
34 In the second step, the designed protein is assembled into a homo-oligomer such that the designed bi
35 t aromatic hydrocarbons were synthesized and assembled into a library of 1296 different tetramer comp
36 other within the SPB and how each protein is assembled into a new structure during SPB duplication.
37 assembly, the trimer of E1/E2 may be further assembled into a pentamer, with 12 pentamers comprising
39 volumes, and diffusing capacity that can be assembled into a report appropriate for a laboratory's p
40 h the rDNA locus while telomeric regions are assembled into a weak heterochromatin that is only mildl
42 structural data revealed that the polymerase assembles into a central polymerase core and several aux
43 This structure showed that leptospiral PerR assembles into a dimer in which a metal-induced conforma
45 7 domain accumulates in the cell nucleus and assembles into a heterotrimeric polymerase with PB1 and
46 combining an alpha-helical peptide that self-assembles into a hexameric coiled-coil bundle and an Fc-
47 A 3D reconstruction revealed that SpoIIIAG assembles into a large and stable 30-fold symmetric comp
50 d, which, when doped with lithium salt, self-assembles into a smectic-ordered ionic liquid crystal th
51 otential to treat obesity and diabetes, self-assembles into a stable nanofibril formulation which sub
52 uanosine monophosphate), which spontaneously assembles into a structure with dimensions that are stri
53 he yeast mitoribosomal central protuberance, assembles into a subcomplex with MrpL7 (uL5), Mrp7 (bL27
54 arF DNA partition protein of the ParA family assembles into a three-dimensional meshwork that uses th
56 composed of heavy and light chain subunits, assembles into a vesicle coat, controlling receptor-medi
60 ian brain, and its encoded gamma2 subunit is assembled into alphabetagamma2 receptors, which are the
61 target interference in vivo Shortened crRNAs assemble into altered-stoichiometry Cascade effector com
62 ull-length and the C-terminal part of PB1-F2 assemble into amyloid structures and disrupt membrane at
64 tes show no cytotoxicity, whereas PB1-F2 pre-assembled into amyloid oligomers or fragmented nanoscale
65 sing the motif, allows prion propagation and assembles into amyloid fibrils, as demonstrated by X-ray
67 loids within minutes, aS takes many hours to assemble into amyloids and pro-IAPP aggregates even slow
68 lations to describe how ADs are able to self-assemble into an aggregate, and, specifically, how tail
69 e hepatitis B virus (HBV) core protein (HBc) assemble into an icosahedral capsid that packages the vi
70 rs, which enables the host to initially self-assemble into an S4-symmetric structure and then subsequ
73 at Sequences, a class of tandem repeats, are assembled into an intermediate chromatin state bearing f
74 is the second largest, with 72 Dy(III) ions assembled into an unprecedented tubular structure, is sy
75 how compelling evidence that amelogenin self-assembles into an amyloid-like structure in vitro and in
76 PRRSV, which exhibits a unique structure and assembles into an asymmetric dimer whose structure is co
77 and hypertrophic growth-plate cartilage and assembles into an extended extracellular network in cult
81 e chirality, so-called homochiral sequences, assemble into antimicrobial pores and form contiguous he
84 ion, these amphiphilic block copolymers self-assemble into bridged flower micelles at high concentrat
85 r ester counterparts 1-4 were proven to self-assemble into C6 and C7 pseudocycles by intramolecular H
86 portion of Synaptotagmin 1 (Syt1) could self-assemble into Ca(2+)-sensitive ring-like oligomers on me
87 abbit reticulocyte lysate (RRL), was able to assemble into capsids when (low-nanomolar) HBc concentra
88 o how other icosahedral viruses reproducibly assemble into capsids with a predetermined T number, alt
89 trast to other assembly systems in which HBc assembles into capsids independently of the CTD under co
90 ed at physiological (low) concentrations and assembles into capsids under near-physiological conditio
91 plain these proteins' compromised ability to assemble into catalytically active supra-tetrameric fila
92 y and the ways in which these molecules self-assembled into cells that could grow, divide and evolve,
93 ncilibacillus cellulovorans' multidomain GHs assembled into cellulase complexes through glycosylation
95 ogical conditions and have the propensity to assemble into co-oligomers with different properties fro
96 of biological membranes and is able to self-assemble into colloidal gold nanoclusters or membranes i
97 ing polymer, monodisperse rod-like particles assemble into colloidal membranes, which are one-rod-len
98 rse mixtures of filamentous viruses can self-assemble into colloidal monolayers with thermodynamicall
99 B. cereus family spores and that it can self-assemble into complex structures that possess many of th
104 concert of four-arm junctions; these in turn assemble into continuous arrays facilitated by sequence-
106 Here, we show that nanoparticles can be assembled into crystalline and open 3D frameworks by con
109 able, we have investigated how proteins that assemble into different types of homomers are associated
110 translation preinitiation complexes that are assembled into discrete granules by specific RNA-binding
115 on lipid monolayers as expected, but instead assembles into dodecameric minirings, often in hexameric
117 differentiate as in the wild type, but AChRs assemble into ectopic clusters that progressively enlarg
118 brane leaflet and activated clotting factors assemble into enzymatically active complexes on the expo
120 etion of basement membrane components, which assemble into fibrils that spool out to elongate the Dro
121 system in which cellulose is synthesized and assembled into fibrils would facilitate detailed study o
127 apes under continuous deposition, ultimately assembling into foam-like microstructures with a highly
129 but how complex multimeric proteins fold and assemble into functional quaternary structures remains u
131 (NM-II) is recruited to those structures and assembled into functional bipolar filaments have remaine
135 nine (G)-rich sequences in nucleic acids can assemble into G-quadruplex structures that involve G-qua
137 slated into stable, full-length proteins and assembled into GJs when expressed in HeLa or Madin-Darby
138 onsists of cells; in some cases, these cells assemble into groups, such as endosymbionts or multicell
139 verage 500-kb-long DNA fragments that can be assembled into haplotype contigs with N50 greater than 7
140 the violent merger of two neutron stars can assemble into heavy elements such as gold and platinum i
142 Spherical colloidal particles generally self-assemble into hexagonal lattices in two dimensions.
143 and EM analyses revealed that TRIM5 proteins assembled into hexagonal nets, both alone and on capsid
144 assignments of Rous sarcoma virus (RSV) CA, assembled into hexamer tubes that mimic the authentic ca
145 erentially and coordinately corecruited TRs, assemble into hierarchical combinations at hepatic CRMs.
146 es at the capsule surface prevents them from assembling into hierarchical structures and leads to the
148 performed and the resulting corrected reads assembled into high-quality hybrid and non-hybrid assemb
151 n subunit composition, yet how a new subunit assembled into higher-order structures confers different
152 le-stranded DNA monomers could dendritically assemble into highly branched nanostructure upon introdu
153 ce, native structure, or function could self-assemble into highly ordered structures known as amyloid
154 ids in proxies for atmospheric aerosols self-assemble into highly ordered three-dimensional nanostruc
155 o)arylboronic acids, and carbon monoxide are assembled into highly elaborate products with good yield
156 like molecular tile units that spontaneously assemble into hollow, crystalline nanotubes in water.
157 llins, Cbln1, Cbln2, and Cbln4, autonomously assemble into homohexamers, whereas the Cbln3 requires C
158 interact with other copies of themselves and assemble into homomeric complexes, the overwhelming majo
161 nd-binding site, but it is poised to rapidly assemble into intracellular signal-generating complexes
162 zed with an O-benzylated UPy derivative self-assemble into lamellar nanostructures regardless of volu
164 ucleosomes has the intrinsic ability to self-assemble into large chromatin globules stabilized by nuc
165 However, although IM30 monomers interact and assemble into large oligomeric ring complexes with diffe
166 their small monomeric weight, they typically assemble into large polydisperse oligomers that vary in
167 o certain anaerobic bacteria, where they are assembled into large multienzyme complexes termed cellul
168 modulin-dependent protein kinase II (CaMKII) assembles into large 12-meric holoenzymes, which is thou
170 ules for the design of single CMPs that self-assemble into long triple helices with perfect symmetry.
171 We now recognize that numerous proteins assemble into macromolecular complexes as part of normal
172 cial mesoscopic atoms, which could then self-assemble into materials structured at a nanoscale, such
173 namics simulation results show that peptoids assemble into membranes through an anisotropic formation
175 pate in reaction cascades have been shown to assemble into metabolons in response to the presence of
176 le, can intercalate hydrated metal ions that assemble into metal oxide films during thermal oxidation
178 ta-1,4-glucan chains polymerized by CesA are assembled into microfibrils that are frequently bundled
179 l cells in three-dimensional co-culture self-assembled into microvessels, and platelet-derived growth
180 odendrimers, together with doxorubicin, self-assembled into monodispersed micelles [NP(BTZ-DOX)] with
181 h both mTOR and GbetaL (also known as MLST8) assemble into mTORC1 and mTORC2, it remains largely uncl
187 eptides tagged with lipophilic moieties self-assemble into nanoparticles until they reach the target
188 sustainable Candida rugose lipase to ordered-assemble into nanoparticles with high catalytic activity
189 of butylene-tethered PBI spontaneously self-assemble into nanoparticles, which constitute an off-pat
191 rombin-binding aptamer amphiphiles that self-assemble into nanoscale polymeric micelles with a densel
192 e peptide that self-replicates and then self-assembles into nanostructures, coupling autocatalytic an
193 t a 2:1 ratio of acceptor to donor molecules assemble into nearly orthogonal mixed stacks in which th
194 molar mixture of the monomer and the hairpin assembles into non-fibrillar aggregates, demonstrating t
196 cytes as soluble monomers, perforin can self-assemble into oligomeric pores of 10-20 nm inner diamete
198 egated into amyloid fibrils, whereas Abeta42 assembled into oligomers that inserted into lipid bilaye
200 mal growth factor (EGF) concentrations, EGFR assembles into oligomers, as indicated by pairwise dista
203 coli, we also demonstrate that ExsY can self-assemble into ordered 2D arrays that mimic the structure
205 hway is initiated by IgG molecules that have assembled into ordered hexamers after binding their Ag o
210 s composed of catalytic large subunits (LSu) assembled into pentamers of dimers, (L2)5, and differs f
211 selected dodecapeptide and its variants self-assemble into peptide nanowires on two-dimensional nanos
212 ding to residues 297-391 of full-length tau) assembles into PHF-like fibrils in vitro without the nee
217 s can serve as molecular tile units that can assemble into precision supramolecular architectures.
218 sequences can be rationally designed to self-assemble into predictable three-dimensional structures.
219 hough monomeric MAVS recombinant protein can assemble into prion-like filaments spontaneously in vitr
221 erials, in which small organic molecules are assembled into regular structures by non-covalent intera
223 pt of amphiphilic molecular motors that self-assemble into responsive supramolecular nanotubes in wat
225 PL26 loci are deleted, plasmid-encoded Rpl26 assembles into ribosomes and localizes to the cytosol.
227 he ATP synthase forms V-shaped dimers, which assemble into rows along the highly curved ridges of lam
231 yl-2'-deoxyguanosine (8ArG) derivatives self-assemble into sets of coaxially stacked planar tetramers
232 ms non-toxic functional amyloid fibrils that assemble into sheets upon which melanins ultimately are
233 Abeta will accelerate fiber formation and co-assemble into short rod-shaped fibers with its full-leng
234 kpoint protein MAD2 and the meiotic HORMADs, assemble into signaling complexes by binding short pepti
237 een (ICG) and epirubicin (EPI) could co-self-assemble into small molecular nanoparticles (NPs) in aqu
238 The protein alpha-synuclein (alphaS) self-assembles into small oligomeric species and subsequently
239 teracting, metal decorated graphene crystals assembled into so-called graphene laminates, consisting
241 rystals coated with polycatenar ligands self-assemble into softer bcc superlattices that deviate from
242 amyloidogenic polypeptides misfold and self assemble into soluble pre-fibrillar aggregates, i.e., pr
243 by maternal messenger RNAs and proteins that assemble into specialized messenger ribonucleoproteins (
244 nd interactive structures programmed to self-assemble into specific patterns, such as those on strain
245 Accordingly, preselected repeats could be assembled into specific binding proteins on demand and t
246 vered by designing cargo molecules that self-assemble into spherical micelles and increase the local
247 constant close to that of alpha-PtO2, either assembling into spoked wheels, 1-5 bar O2, or closely pa
248 re, we report that Myrf N-terminal fragments assemble into stable homo-trimers before ER release.
251 , and upon precipitation into water, readily assembled into stable nanoaggregates that transformed ci
252 forms amphiphilic parallel beta-sheets that assemble into stacked bilayers with alternating hydropho
253 a point mutation from the wild-type strain, assembles into straight filaments in which flagellin mon
254 ific peptides have been demonstrated to self-assemble into structurally defined nanoscale objects inc
255 dary neurons of lineages DALcl1/2 and DALv2, assemble into structurally distinct primordia of the AOT
256 r7Ni} rings, which act as the qubits, can be assembled into structures suitable for either the CNOT o
257 1.6 muM) without blocking RAD51's ability to assemble into subnuclear foci at sites of DNA damage.
258 ns, mitochondrial complex I is predominantly assembled into supercomplexes, whereas in astrocytes the
260 e molecular mechanism by which the EMPs self-assemble into supramolecular structures and demonstrate
261 bacteriochlorophyll (BChl) c, d, or e, which assemble into supramolecular, nanotubular structures in
262 which fluorophore-labeled DNA hairpins self-assemble into tethered fluorescent amplification polymer
263 pearance and shows that A- and B-type lamins assemble into tetrameric filaments of 3.5 nm thickness.
264 show that complementary fragments of IP3 R1 assemble into tetrameric structures and retain their abi
265 provides a structural insight on how Bdp1 is assembled into TFIIIB complexes, reveals structural and
267 herichia coli have been identified, how they assemble into the divisome and synthesize the septum rem
269 ns, and understanding how these nucleoporins assemble into the NPC scaffold imposes a formidable chal
270 cs by which six different nucleolar proteins assemble into the nucleoli of Drosophila melanogaster em
271 er dysbindin-interacting polypeptides, which assemble into the octameric biogenesis of lysosome-relat
272 anism by which enamel matrix proteins (EMPs) assemble into the organic matrix remains poorly understo
273 he ability of beta-tubulin to fold or become assembled into the alpha/beta-heterodimer, nor did it in
274 without this subunit, no other subunits are assembled into the head, and enabled identification of a
275 uestions remain about how these proteins are assembled into the OM after their synthesis in the cytop
276 the core centromeric regions may not yet be assembled into the pseudochromosomes of the reference ge
277 d with a unique beta-triangle insertion that assembles into the prominent channel, the dimensions of
281 tic-specified endoderm iPSCs (HE-iPSCs) self-assembled into three-dimensional organoids, resulting in
282 The protein alpha-synuclein (alphaS) self-assembles into toxic beta-sheet aggregates in Parkinson'
286 The products of these genes are thought to assemble into two non-canonical multisubunit RNAPs - a v
287 functionalized with reactive arms have been assembled into two- and three-tiered covalent stacks thr
289 sher pathway, are polymers of pilus subunits assembling into two parts: a thin, short tip fibrillum a
290 aceted coiled-coil peptide helix, which self-assembles into ultrasmall, monodisperse, anionic virus-l
292 anged germline V, D, J segments (that can be assembled into variable region exons that encode bnAb pr
293 s that graphene derivatives at the nanoscale assemble into various architectures of nanocrystals in a
294 A surface adapter that can programmably self-assemble into various chiral supramolecular architecture
295 c groups, which allow the constructs to self-assemble into various nanostructures in aqueous solution
296 rsed in aqueous solutions, they tend to self-assemble into vesicles of various shapes and sizes by vi
297 nt also showed a markedly reduced ability to assemble into viral particles and had reduced antiviral
299 a nonresponsive water-soluble block can self-assemble into well-defined polymersomes with narrow size
300 ; in turn, multicellular organisms sometimes assemble into yet other groups, such as primate societie
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