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1 in-protein ligases), and E4 (ubiquitin chain assembly factors).
2 l for photoautotrophy, functioning as a PS I assembly factor.
3 Scm3 functions as a Cse4-specific nucleosome assembly factor.
4 RAVE is the first isoform-specific V-ATPase assembly factor.
5 U5 small nuclear ribonucleoprotein particle assembly factor.
6 ive hepatopathy due to mutated BCS1L, a CIII assembly factor.
7 am68l-1 mutant identifies PAM68L as an NDH-C assembly factor.
8 etion substrate, needle cap, and injectisome assembly factor.
9 tro, demonstrating that HJURP is a chromatin assembly factor.
10 n combination with voa1Delta, a nonessential assembly factor.
11 the flavoprotein of complex II and the SdhE assembly factor.
12 modulating the levels of TPX2, a key spindle assembly factor.
13 edicated transcription factor and a ribosome assembly factor.
14 s, we validated C17orf89 as a complex I (CI) assembly factor.
15 on in complex I assembly as a plant-specific assembly factor.
16 mplicated multistep process that is aided by assembly factors.
17 pwise fashion through the actions of several assembly factors.
18 stead of binding DNA, Teb2 and Teb3 are Teb1 assembly factors.
19 also RNA-processing, translation and protein assembly factors.
20 action by transportin binding and inhibiting assembly factors.
21 ith both the RNA surveillance system and SRP assembly factors.
22 mplexes depends on the activity of dedicated assembly factors.
23 eotide cofactor require the participation of assembly factors.
24 protein (HJURP) coupled with other chromatin assembly factors.
25 nuclear-encoded accessory proteins known as assembly factors.
26 cellular distribution of several soluble COX assembly factors.
27 regulated process that requires a number of assembly factors.
28 DNA (mtDNA)-encoded subunits or 14 known CI assembly factors.
29 2 of the nuclear-encoded subunits and in six assembly factors.
30 2 and Cox10 are previously characterized CcO assembly factors.
31 uding strains with deletions or mutations of assembly factors.
32 ecause it locally activates critical spindle assembly factors.
33 Formins are potent actin assembly factors.
34 ents for most genes encoding OXPHOS subunits/assembly factors.
35 participation of a large number of ribosome assembly factors.
36 l (dTACC), two MAPs that function as spindle assembly factors.
37 se function of each of the approximately 200 assembly factors.
38 is a complex process facilitated by several assembly factors.
39 ompanied by the accumulation of PSI-specific assembly factors.
40 ermediate that exhibits low affinity for the assembly factors.
42 ti-silencing function 1 (Asf1) and Chromatin Assembly Factor 1 (CAF-1) chaperone histones H3/H4 durin
49 anti-silencing factor 1 (Asf1) to chromatin assembly factor 1 (CAF-1), another histone chaperone tha
52 subunit of the chromatin modifier chromatin assembly factor 1 and it regulates H3K9 trimethylation o
53 ereas the histone chaperone CAF-1 (chromatin assembly factor 1) in humans and Caf1 in Drosophila are
54 -associated protein 1 (NuSAP1) and chromatin assembly factor 1, subunit B (p60; CHAF1b) as targets of
55 vestigate mutants dysfunctional in chromatin assembly factor-1 (CAF-1) (fas1 and fas2 mutants), which
58 cycle stages, whereas knockdown of chromatin assembly factor 1b (CAF-1b) revealed derepression predom
59 een, and a knockdown mutant (sdhaf2) for SDH assembly factor 2 that is required for FAD insertion int
61 lab suggests that a group of interdependent assembly factors (A(3) factors) is necessary to create e
65 aryotes requires approximately 200 essential assembly factors (AFs) and occurs through ordered events
69 ast Saccharomyces cerevisiae with two mutant assembly factor alleles, VMA21 with a dysfunctional ER r
70 se that multiple factors, including the SdhE assembly factor and bound dicarboxylates, stimulate cova
71 hese studies identify how the conserved SdhE assembly factor and its homologs participate in complex
72 his study defines a new membrane-embedded CI assembly factor and provides a resource for further anal
73 e functions of most of the approximately 200 assembly factors and 79 ribosomal proteins required to c
75 proteins to interact with multiple, distant assembly factors and functional ribosomal RNA elements,
78 ns and mechanisms of function of the various assembly factors and pathways by which exogenous antigen
79 ucturing events coincide with the release of assembly factors and predict that completion of the head
80 ever, detailed insights into the function of assembly factors and ribosomal RNA folding events are la
81 s of the newly synthesized cytochrome b with assembly factors and structural complex III subunits.
82 tein-only pre-snoRNP complex containing five assembly factors and two core proteins, 15.5K and Nop58;
83 F1), II (SDHAF2), III (UQCC2), and IV (SCO1) assembly factors and was required for stability of respi
84 initiation factor, securin gene, nucleosome assembly factor, and a subunit of the cohesin complex) b
85 of the viral RNA polymerase complex, a viral assembly factor, and an inhibitor of host interferon (IF
86 ting mitochondrial chaperone, OXPHOS complex assembly factor, and glycolysis genes, ATFS-1 bound dire
87 -affected mutant68 (PAM68), a photosystem II assembly factor, and photosynthesis-affected mutant68-li
88 Scm3 functions as a Cse4-specific nucleosome assembly factor, and that the resulting octameric nucleo
93 includes replication factor C, the chromatin assembly factor Asf1p, and the K56-specific acetyltransf
95 ing defect of pol30 mutants to the chromatin assembly factors Asf1p and CAF-1, we found pol30 mutants
96 Cox3, supporting the idea that supercomplex assembly factors associate with Cox3 and demonstrating t
97 In Saccharomyces cerevisiae, more than 180 assembly factors associate with preribosomes to enable f
98 as confirmed TMEM126B as the tenth complex I assembly factor associated with human disease and valida
100 they do in spindles, whereas two key midzone assembly factors, Aurora B and Kif4, act as they do in m
102 e deacetylase modifier SPOP and in chromatin assembly factor BAZ1A, in nearly two thirds of cases.
103 nce, and provide the first evidence of actin assembly factors being required to repair myofibrils.
104 functional inactivation of the 60S ribosome assembly factor Bop1 in a 3T3 cell model markedly increa
105 e Cox1 degradation in cells lacking the Coa2 assembly factor, but not in a series of other mutants st
106 d at centromeres by the HJURP/Scm3 family of assembly factors, but homologues of these chaperones are
107 bosome biogenesis involves approximately 200 assembly factors, but how these contribute to ribosome m
109 re, we show the involvement of two chromatin assembly factors (CAFs), Asf1 and CAF-1, in turning off
111 le, and loss or accumulation of such spindle assembly factors can result in aneuploidy and cancer.
112 Rubisco-interacting proteins, photosystem I assembly factor candidates, and inorganic carbon flux co
116 tal of 21 known and potentially new ribosome assembly factors co-localized with various ribosomal par
118 cells lacking the cytochrome c oxidase (CcO) assembly factor Coa2 are impaired in Cox1 maturation and
120 mutations were recently reported in one such assembly factor, COA6, and our previous work linked Coa6
122 ociated with multiple members of the MCIA CI assembly factor complex and core CI subunits and was loc
124 spliceosomal small nuclear ribonucleoprotein assembly factor conserved from yeast to humans, modulate
125 ich Scm3(Sp) acts as a CENP-A(Cnp1) receptor/assembly factor, cooperating with Mis16 and Mis18 to rec
126 poorly understood how the timing of spindle assembly factor degradation is established during mitosi
128 strain, we show that the requirement for the assembly factor depends on the cellular redox environmen
130 phoinositide-rich membranes, whereas F-actin assembly factors Dia2 and N-WASP reside on phosphoinosit
139 Soper et al. determine the specific role of assembly factors during the final stages of ribosomal su
140 Functional tests show that two key spindle assembly factors, dynein and kinesin-5, act during assem
143 ar weight complexes combined with regulatory/assembly factors essential for expression of this subuni
146 pen reading frame YDR381C-A) as an important assembly factor for complex III, complex IV, and their s
147 in the survival motor neuron (SMN)1 gene, an assembly factor for loading the Sm complex on snRNAs and
150 ssociates with the Ycf39 protein, a putative assembly factor for photosystem II, and with the YidC/Al
153 questration, thus down-regulating release of assembly factors from importin beta, and 2) direct actio
154 bosome assembly intermediates and associated assembly factors from wild-type Escherichia coli cells u
156 er determine the order of association of all assembly factors functioning in one step of ribosome ass
159 ion mediator Rad22 (Sc Rad52), the chromatin assembly factor Hip1 (Sc Hir1), and the Msc1 protein rel
161 er68 eliminates the binding of CENP-A to the assembly factor HJURP, thus preventing the premature loa
163 ng domain 1 (FOXRED1) protein is a complex I assembly factor; however, its specific role in the assem
164 have been described for eukaryotic ribosome assembly factors; however, this work describes an exampl
166 Specifically, mutations in four conserved assembly factors impinging the biogenesis of the mitocho
169 is revealed an unexpected role for ribosomal assembly factors in controlling stem cell cytokinesis.
171 nges in the levels of ribosomal proteins and assembly factors in preribosomes when RPLs functioning i
172 Importin beta is known to act by repressing assembly factors in regions distant from chromatin, wher
174 eveal functional redundancy between specific assembly factors in the chromatin pathway, suggesting in
175 atory control and is aided by a multitude of assembly factors in vivo, but can also be carried out in
177 les with peptides is orchestrated by several assembly factors including the transporter associated wi
178 multiple DNA replication-coupled nucleosome assembly factors, including Rtt106, CAF-1, and lysine re
179 e catalytic subunits of CIII and COX10 is an assembly factor indispensable for the maturation of Cox1
181 ion or inhibition of human complex II or its assembly factors is often associated with neurodegenerat
182 With 44 structural subunits and over 10 assembly factors, it is unsurprising that complex I defi
183 be essential for biogenesis, since dedicated assembly factors keep immature ribosomal subunits apart
184 ith mutations in genes that encode other OMP assembly factors leads to severe synthetic phenotypes, s
186 cal homology with Vma22p, the yeast V-ATPase assembly factor located in the endoplasmic reticulum (ER
187 bosome assembly, where it phosphorylates the assembly factor Ltv1, which causes its release from nasc
188 we demonstrate an interaction between CENP-A assembly factor M18BP1 and acetyltransferase KAT7/HBO1/M
189 in biogenesis is orchestrated by hundreds of assembly factors, many of which are yet to be discovered
190 biogenesis, and defects in a single ribosome assembly factor may be lethal or produce tissue-specific
191 Because of concerns that vascular plant assembly factors may not be adequate for assembly of a c
192 itself, in the absence of any chaperones or assembly factors, may serve as a platform for the transf
193 that Mss116 interacts with the mitoribosome assembly factor Mrh4, is required for efficient mitoribo
194 ing mutations in FLASH, mutations in the HLB assembly factor Mxc, or depletion of the variant histone
195 A12), whereas a paralog of this subunit, the assembly factor N7BML (NDUFAF2), was found firmly bound
197 his network includes genes encoding core and assembly factors needed to build the complete 26S partic
198 pose that such mutual exclusivity of cluster assembly factor (Nfs1/Yfh1) and cluster transfer factor
207 tein, renamed here alpha-carboxysome RuBisCO assembly factor (or acRAF), is a novel RuBisCO chaperone
208 ain insertions in genes encoding components, assembly factors, or regulators of type IV pili or conta
210 ctor governing the usage of one Fe-S cluster assembly factor over another in the maturation of apo-pr
211 ions (e.g., antibiotics, deletion mutants of assembly factors, oxidative stress, nutrient deprivation
212 , we reveal a novel role for the microtubule assembly factor p25 in regulating stabilization and elon
213 tematic analysis of one such uncharacterized assembly factor, Pet117, and demonstrate in Saccharomyce
215 ulation of the kinase into large spliceosome assembly factor-positive speckle domains within the nucl
216 by the presence of the photosystem II (PSII) assembly factor PratA (for processing-associated TPR pro
217 membrane subcompartment harboring the early assembly factor PratA and are referred to as PratA-defin
218 x10, a gene encoding a cytochrome IV oxidase assembly factor, prevented the metabolic shift induced b
219 lecular associations of 15 core subunits and assembly factors previously linked to human CI deficienc
220 shown here to be distinct from the chromatin assembly factors previously shown to load other histone
221 terized partially, and at least 12 extrinsic assembly factor proteins are required for the assembly o
222 s coordinated by at least thirteen extrinsic assembly factor proteins that are not part of the fully
223 and possible function of two homologous PSII assembly factors, Psb28-1 and Psb28-2, from the cyanobac
224 and possible function of two homologous PSII assembly factors, Psb28-1 and Psb28-2, from the cyanobac
225 of disassembled V-ATPase (V1 domain) to its assembly factor RAVE (subunit Rav1p) was 5-fold enhanced
226 ture and pre-30S complexes in the absence of assembly factors RbfA and RimM revealed global reorganiz
227 esolution, revealing in molecular detail how assembly factors regulate the timely folding of pre-18S
228 Collectively, our results suggest that 40S assembly factors regulate the timely incorporation of ri
229 er enzymes, transport proteins, and membrane assembly factors relative to their equivalent gel bands
232 ngly, additional copies of an extraribosomal assembly factor, RimJ, rescued all the phenotypes associ
234 lude most of the major functional classes of assembly factors: RNA-binding proteins, scaffolding prot
236 lamin B, the spindle matrix contains spindle assembly factors (SAFs) such as Eg5 and dynein which are
237 hrough the release of importin-bound spindle assembly factors (SAFs), which stimulate microtubule (MT
238 racts with the endoplasmic reticulum droplet assembly factors seipin and Fit2 to maintain proper drop
240 r form the binding surface for the H/ACA RNP assembly factor SHQ1 and that DC mutations modulate the
241 iana by an interaction between ARC6, an FtsZ assembly factor spanning the inner envelope membrane, an
243 zation is tightly regulated by activation of assembly factors such as the Arp2/3 complex and formins
245 g MidA (C2orf56/PRO1853/Ndufaf7), another CI assembly factor, suggesting that autophagy activation mi
246 t msk-null mutants are depleted of the snRNP assembly factor, survival motor neuron, and the Cajal bo
247 xes between calreticulin and the MHC class I assembly factor tapasin and are important for maintainin
249 ty complex (MHC) class I molecules and their assembly factor tapasin, thereby influencing antigen pre
254 ese results is that Mediator functions as an assembly factor that facilitates PIC maturation through
256 n Cep290/Mks4/Nphp6 orthologue) as a central assembly factor that is specific for established MKS mod
257 ce showing that Cox25 is a new essential COX assembly factor that plays some roles similar to Cox14.
258 his work describes an example of a bacterial assembly factor that tests a specific translation mechan
260 are nucleated at centrosomes and by spindle assembly factors that are activated in the vicinity of c
261 he spatial coordination of the ribosome with assembly factors that are critical for enzyme biogenesis
262 aryotes involves the activity of hundreds of assembly factors that direct the hierarchical assembly o
263 Bol1 and Bol3 as specific mitochondrial ISC assembly factors that facilitate [4Fe-4S] cluster insert
264 ess (Asl) are essential, conserved centriole assembly factors that induce centriole amplification whe
265 elusive, and the roles of any additional CcO assembly factors that may be involved remain unclear.
268 ogue 1 (PES1), an essential 60S-preribosomal assembly factor, thereby impairing exonuclease-mediated
269 One such event is found in the complex I assembly factor TIMMDC1 establishing a novel disease-ass
270 The characteristics of C3orf1, of another assembly factor, TMEM126B, and of NDUFA11 suggest that t
271 and two previously uncharacterised V-ATPase assembly factors, TMEM199 and CCDC115, stabilise HIF1alp
272 Ran control the abundance of active spindle assembly factors to achieve the accurate formation of th
274 es cellular mechanisms for recruiting CENP-A assembly factors to existing CENP-A nucleosomes for the
275 nesin-5 motor Eg5 interacts with the spindle assembly factor TPX2, but how this interaction contribut
276 mportin alpha by GM130 liberates the spindle assembly factor TPX2, which activates Aurora-A kinase an
278 beta5pro is functionally linked to the Ump1 assembly factor, trans-expressed beta5pro associates onl
279 S translational active sites, the associated assembly factors Tsr1, Enp1, Rio2 and Pno1 collectively
280 bonucleoprotein particles (UsnRNPs) requires assembly factors united in protein arginine methyltransf
281 nd VopF (VopL/F) are tandem WH2-domain actin assembly factors used by infectious Vibrio species to in
282 e show the wBm is active since the essential assembly factor virB8-1, is transcribed in adult worms a
283 as the functional ortholog of yeast V-ATPase assembly factor Voa1 and reveals a novel link of tissue-
287 ystem from the Wnt5 guidance cue to an actin assembly factor, we propose that the Wnt5/PCP navigation
288 reconstitution of competition between actin assembly factors, we found that the small G-actin bindin
290 ions and determine the structures of over 20 assembly factors, which are enriched in two areas: an ar
291 ing nuclear-encoding structural subunits and assembly factors, whilst only 3 of the 10 patients with
292 s C20orf7) is a mitochondrial complex I (CI) assembly factor whose mutations lead to human mitochondr
293 acts as a scaffold to recruit multiple actin assembly factors whose functions are normally regulated
295 rb1 mutants: association of twelve different assembly factors with domain V of 25S rRNA, including th
296 table assembly of seven other interdependent assembly factors with pre-60S subunits, resulting in tur
300 ding indicates that, along with acting as an assembly factor, YjeQ has a role as a checkpoint protein
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