コーパス検索結果 (1語後でソート)
通し番号をクリックするとPubMedの該当ページを表示します
1 tion and dissociation rate constants and the association constant).
2 fourth transmembrane helix to predict their association constant.
3 r population and 510(5)-fold increase of the association constant.
4 y the number of sites but hardly changes the association constant.
5 crystal or liquid) and the other with a self-association constant.
6 icantly increase or decrease the equilibrium association constant.
7 se, our method finds the correct pathway and association constants.
8 his experimental measurement on the apparent association constants.
9 isotherm and allow the determination of ion association constants.
10 ties of the AFM to determine protein-protein association constants.
11 ts requires quantification of state-specific association constants.
12 gree well with the experimentally determined association constants.
14 ptionally weak affinity of MgATP for myosin (association constant, 0.2 mM(-1)), and a unique rate-lim
16 antigen-antibody complex demonstrates a high association constant (5x10(12)L/mol) that results in hig
17 ologous alpha/beta complex displays a larger association constant [(6.6 +/- 0.4) x 10(6) M(-1)] than
19 where folded conformers are scarce, then the association constant and enantioselectivity clearly drop
20 olyte concentrations allowed us to obtain an association constant and free energy change for ion pair
28 s from this study suggest that the different association constants and formation of an intermediate c
29 cant errors in the evaluation of equilibrium association constants and the fractional coverage of mem
30 the direct determination of the equilibrium association constants and thermodynamic parameters of tr
31 statistics is used to determine histone-DNA association constants and to test for differences in the
34 e mutants showed significantly lower K0 (ADP association constant) and larger K4 (equilibrium constan
35 ine the receptor's stoichiometry of binding, association constants, and both the enthalpy and entropy
36 und to be stable, demonstrated fast receptor association constants, and showed high specificity for a
37 of two classes of calcium-binding sites with association constants approximately 10(7.5) and approxim
38 t that those receptors that display the best association constants are able to sample folded conforma
40 Surprisingly, the PKA-RIalpha state-specific association constants are comparable to those of a struc
42 ely bound and cleaved, but in this case, the association constants are significantly lower ( approxim
43 rs also form duplexes, but the observed self-association constants are strongly affected by folding e
48 ts, where the tracer assay predicts the same association constant as a traditional displacement compe
49 tion, expressing the experimentally observed association constant as the sum of products, each valid
50 fullerene-based guest molecules and present association constants as high as approximately 5 x 10(8)
51 relate closely with literature values of the association constants between the respective ligands and
52 he large differences seen in the equilibrium association constants between the unlinked and covalentl
55 s to the periphery of one dendron lowers the association constant by almost an order of magnitude.
56 This effect, which can reduce the apparent association constant by more than 60%, is found to be mo
57 n a near 1000-fold change in the equilibrium association constant, by varying the spatial distributio
58 nding experiments showed the presence of two association constants corresponding to high-affinity (Ka
65 n it was necessary to include the non-band 3 association constants determined from chymotrypsin-treat
67 (1/2-I)) was 0.77 h, increasing the antibody association constant enhanced AUC(C(IAR)) much more than
68 ative; that is, the ratios of the individual association constants exceeded the expected statistical
70 concentration dependence, but the ratios of association constants followed the expected statistical
71 ity and very tight binding, with an apparent association constant for C5O5(2-) of 5 x 10(10) M(-1).
72 imentation equilibrium results show that the association constant for dimerization of EI-C monomers i
74 pe H-chain ferritin whereas the enthalpy and association constant for Fe(2+) binding are similar for
76 urements reveal a systematic increase in the association constant for H.G1, H.G2, and H.G3 with a cha
77 near the middle of the domain decreases the association constant for human SIRPalpha to about one-th
84 method for the simultaneous determination of association constants for a guest binding to seven diffe
85 The protein/peptide data combined with the association constants for binding of each proline-rich p
89 ghts in the range 10-330 kDa and equilibrium association constants for dimer formation in the range 2
91 e significantly steeper salt dependencies in association constants for noncognate loops, aiding discr
93 orted (Ka = 1.9 x 10(6) M(-1)) and very high association constants for paraquats (Ka > 10(5) M(-1)) i
94 etonitrile solution containing 2% water, the association constants for the 1:1 binding interaction be
96 d ESI-MS assay, the proxy ligand method, the association constants for the CBM-B2NGL and CTB5-GM1 int
101 ctions (complex [5.6]), but only reduces the association constant in CH3CN by 2 orders of magnitude (
103 e a general method to measure state-specific association constants in allosteric sensors based on thr
107 nd HisG form inactive but stable dimers with association constants in the range of 2.5-3.3 x 10(5) M(
108 ituents on the bisurea binding pocket showed association constants in the range of 200-400 M(-1) in t
110 2N(CH)nNH2, n = 6, 7, 8, 9, 10, 11, 12), the association constants increase as the length of the alka
111 i.e., statistical, and the average apparent association constant increased by nearly 5-fold; this ef
114 rom calculations based on a constant complex association constant is found and explained by a reduced
117 of the cavity (cf. Rebek's 55% rule), so the association constant is sensitive to shape complementari
118 ty of the ratio of specific and non-specific association constants is consistent with an osmotic, rat
119 ds weakly within the oligomer cavity with an association constant K(a) = 2 M(-1), and the oligomer-me
120 in analogous complexes exhibited the highest association constant K(a) = 5.0 x 10(6) M(-1) in acetone
121 affinity for K5 was quantified, yielding an association constant K(a) approximately 2.08 x 10(4) mM(
123 adiometrically to give the cryptophane-radon association constant K(a)=49,000 +/- 12,000 M(-1) at 293
124 in concentration dependence of the apparent association constant K(a,exp), (= [complex]/[H][G(2+)2X(
125 ar association reaction A + B --> AB with an association constant K(AB) is to equate chemical potenti
126 that the potency achieved by increasing the association constant k(on) can be very different from th
127 In CD(3)CN and CD(3)COCD(3) the individual association constants K(1), K(2), and K(3) for 1:1, 1:2,
128 (3) for all three generations the individual association constants K(1), K(2), and K(3) for [2]-, [3]
129 e of the individual antibody fragments (with association constants K(A) and K(B)) by p(d(0))K(B) or p
130 measurements to determine the noncooperative association constants K(ds) to double-stranded DNA for g
131 cognition in a 1:1 motif.(1) The equilibrium association constant (K(1)) for complexation of a specif
132 detachment step (K(2)), the phosphate (P(i)) association constant (K(5)) and the equilibrium constant
133 thermal titration calorimetry to measure the association constant (K(a)) and stoichiometry (n) values
134 temperature (22 degrees C), the equilibrium association constant (K(a)) calculated in the presence o
135 termination of the site-specific equilibrium association constant (K(A)) for a DNA-binding protein.
137 mathematical framework for establishing the association constant (K(a)) for protein-ligand binding b
139 tion between the GABP subunits determined an association constant (K(A)) of 6.0 x 10(8) M(-1) and tha
140 ive manner and with a consistent equilibrium association constant (K(a)) value of 2 x 10(6) M(-1) per
141 n is made possible by determining an average association constant (K(AVE)) for the binding of each re
142 specific binding of leptin to HSCs, with an association constant (K(d)) equal to 660 +/- 5.8 pmol/L.
143 of binding sites (N) and the number average association constant (K(n)()) were calculated for each p
144 onic composition on the apparent equilibrium association constant (K) for the formation of a 1:1 incl
146 SA with a rank order of apparent equilibrium association constants (K(a) values): desflurane > isoflu
147 peptidic guests in all solvent systems have association constants (K(A)'s) in the range of 1 x 10(4)
148 fraction bound to humic superstructures and association constants (K(a)) and Gibbs free energies of
149 that contain a variety of functional groups, association constants (K(A)) for N-Ac-Trp, indole, N-Ac-
151 (4-hydroxy-3-nitrophenyl)acetyl hapten with association constants (K(a)s) of only 1.2 x 10(5) M(-1)
152 technique for measuring the non-cooperative association constants (K(ds)) to double-stranded DNA to
155 ognate nsp3a with high affinity (equilibrium association constant [K(a)], [1.4 +/- 0.3] x 10(6) M(-1)
156 rse rate constant, k(r), and the equilibrium association constant, K(a), for binding of neutrophils t
160 K, a fraction of tetraradicals form a dimer (association constant, K(assoc) approximately 60 M(-1)),
162 interaction, it was possible to calculate an association constant, K(POLY), for the binding of the di
163 luster and divalent dialkylammonium ions, an association constant, K(POLY), was calculated from the v
164 with dielectric constants of 10 or less, ion association constants, K(A), are as much as 2 orders of
165 mately 2 orders of magnitude higher than the association constants, K(A), for the component interacti
167 ile, however, BlueCage6 PF6 exhibits a lower association constant Ka than its progenitor ExCage6 PF6.
170 e calculated change in enthalpy (DeltaH) and association constant (Ka) became greater as the oligomer
175 s with guests containing aromatic rings with association constants (Ka) ranging from 10(2) to 10(6) M
178 ) has been used to determine the equilibrium association constants (Ka), desorption rate constants (k
180 -linked protonation and pH dependence of the association constant (Kb) for the enzyme-aminoglycoside
181 hboring Pc1 molecules and gives rise to high association constants (KD approximately 10(11) M(-1)).
183 are believed to be the first evaluations of association constants leading to a [4]-pseudorotaxane.
184 s behavior is identical to that observed for association constants measured for the formation of 1:1
185 To our knowledge, this is the first reported association constant measurement between a protein and s
186 han Arixtra, which correlates with data from association constant measurements for CCL7-disulfated CC
188 and 30 mM Tris (pH 7.5)], a complex with an association constant of > or = 10(9) M(-1) was observed,
189 ction is significantly weaker, exhibiting an association constant of (3.0 +/- 0.6) x 10(6) M(-1).
191 lpha CD-EF (alpha/alpha) complex displays an association constant of (7.6 +/- 0.4) x 10(7) M(-1).
194 that Q7 binds to insulin with an equilibrium association constant of 1.5 x 10(6) M(-1) and with 50-10
195 binding, with the largest directly measured association constant of 1.7 x 10(9) M(-1) in 75:25 water
196 interacts with mGzmA, but not hGzmA, with an association constant of 1.9 +/- 0.8 x 10(5) M(-1) s(-1)
199 scherichia coli IscA binds iron with an iron association constant of 2.0 x 10(19) M(-1) in vitro.
200 o 30 S subunits with an observed equilibrium association constant of 2.0 x 10(6) m(-1), indicating th
203 ence titration reveals a 1:1 complex with an association constant of 2.63 +/- 0.05 x 10(5) M(-1).
205 sulfur cluster assembly protein with an iron association constant of 3.0 x 10(19) m(-1), is able to o
207 fluorescence quenching assay to have a xenon association constant of 33,000 M(-1) at 293 K, which is
208 y specific interaction to protein (LDL) with association constant of 33.4 kM(-1) s(-1) indicating hig
210 r physiological conditions, with a weak self-association constant of 6.5 x 10(4) M(-)(1) for the mono
212 itration calorimetry (ITC) studies reveal an association constant of approximately 2 x 10(5) M(-)(1)
213 ical ultracentrifugation yielded an apparent association constant of approximately 3 x 10(6) M(-1) fo
214 Competitive assays are used to measure the association constant of complementary strand DNA hybridi
217 he 10-bp site match site with an equilibrium association constant of K(a) = 7.5 x 10(10) M(-1) and di
218 nearly 2 orders of magnitude, and (iii) the association constant of Keap1 for zinc is 1.02 (+/-0.19)
219 hylamino-substituted derivative has a proton association constant of log beta = 4.7, and the disubsti
221 en-bonding ability of the solvents while the association constant of the corresponding sites does not
222 ows us to quantify the stoichiometry and the association constant of the EGFR-Grb2 binding interactio
223 ng the acetic acid concentration affects the association constant of the enantiomers more than the nu
224 reases three to four orders of magnitude the association constant of the functional hexamer; ii), shi
225 0.2 to 0.9 M causes a large decrease in the association constant of the highest energy sites in CH(2
226 gle molecule method for measuring K(ss), the association constant of these proteins to single-strande
230 orms 1:1 complexes with C(60) and C(70) with association constants of 1.4 x 10(5) M(-1) (C(60)) and 1
232 (2+) cooperatively with stepwise macroscopic association constants of 1.73 x 10 (6) and 8.06 x 10 (6)
235 ding is sequential with apparent macroscopic association constants of 2.78 x 10 (4) and 170 M (-1).
236 200 molecules/microm(2) and two-dimensional association constants of 3.1 and 630 microm(2) for bival
237 ble dimer that binds both cGMP and cAMP with association constants of 3.7 x 10(4) M(-1) for [(3)H]cGM
240 uadruplex DNAs is characterized by intrinsic association constants of approximately 2 x 10(5) M(-1) (
242 PC are 1.0 and 0.4 M(-1); the intrinsic 1:1 association constants of Ba and Mg with PS are 1.9 and 1
243 provides the best fit and the intrinsic 1:1 association constants of Ba, Mg, and Ca with acidic grou
245 rometry (nano-ESI TOF MS), we determined the association constants of C-C motif chemokine 7 (CCL7) wi
246 .7, and the disubstituted derivative has two association constants of log beta = 6.2 and 12.1 in etha
247 In the presence of ammonium cations, the association constants of nitrate binding reach an impres
248 ed greatly (4 x 10(4)-150 x 10(4)) while the association constants of several acyl-coenzyme A derivat
249 otropy titration experiments showed that the association constants of the bZIP at 20 degrees C with t
253 The basket binds small molecule guests with association constants of up to 10(4) M(-1) in mesitylene
256 e and the ratio of non-specific and specific association constants on water activity, salt concentrat
257 ; for larger C12 and C13 cyclic ketones, the association constant progressively decreases as the gues
261 tary unit, with no observable changes in the association constants regardless of the degree of functi
263 egardless of the structural state of betalg, association constants remained in the same order of magn
267 taining these mutations gave higher relative association constants, suggesting altered TM-TM interact
270 aK(ATPase) complexes allowed the equilibrium association constants to be brought into an experimental
272 h a wide range of hydrophobicities and whose association constants to HSA cover 3 orders of magnitude
273 (aze(2-)) have shown adipate preference with association constant value of K = 4900 M(-1) in a H2O/DM
274 e other methods for the determination of the association constant values (Ka) and the interaction ene
282 rdium without regulatory proteins, the MgATP association constant was approximately the same, and the
283 calorimetry studies revealed that the PIP-H1 association constant was one order of magnitude higher t
284 in a monomer-dimer equilibrium, although the association constant was significantly less than that re
285 The binding free energy change (hence, the association constant) was nearly invariant over this tem
291 e equimolar solutions (<1 mM) of CxC and AyA association constants were estimated for the formation o
292 s peripheral groups were prepared, and their association constants were measured by (1)H NMR in CDCl(
293 eakens protein binding, unbiased protein-RNA association constants were obtained in competition exper
295 dissolution of 1a (reflective of the overall association constant which is too high to measure) incre
296 ion predominantly depends on its multivalent association constant, which itself exponentially increas
298 termination of their low-temperature (212 K) association constants with C6F5I as 2.9 +/- 0.2, 2.5 +/-
299 phobic effects, and bicyclic substrates have association constants with the calix[4]resorcarene large
300 eriments showed that at this temperature the association constants with the PRDI binding site are 1.1
WebLSDに未収録の専門用語(用法)は "新規対訳" から投稿できます。