ライフサイエンスコーパス: asymmetric hydrogenation

1 action has to be classified as heterogeneous asymmetric hydrogenation.

2 ,3]-sigmatropic rearrangement with catalytic asymmetric hydrogenation.

3 ial utility of more earth-abundant metals in asymmetric hydrogenation.

4 for the electronic effects often observed in asymmetric hydrogenation.

5 tion reaction followed by a PtO(2)-catalyzed asymmetric hydrogenation.

6 Asymmetric hydrogenations are increasingly being used to

7 d remote homoallylic hydroxyl group-directed asymmetric hydrogenation at ambient temperature and pres

8 etric hydroboration is diverted to catalytic asymmetric hydrogenation (CAH) upon the addition of a pr

9 stimulated the development of heterogeneous asymmetric hydrogenation catalysis.

10 ly chiral ligands were found to be effective asymmetric hydrogenation catalysts for the reduction of

11 innamates and subsequent ruthenium-catalyzed asymmetric hydrogenation conditions affording the desire

12 lement in many important reactions including asymmetric hydrogenation, epoxidation and lithiation.

13 s undertaken to demonstrate the potential of asymmetric hydrogenations mediated by the chiral, carben

14 This is demonstrated for the Rh-catalyzed asymmetric hydrogenation of (E)-beta-aryl-N-acetyl enami

15 catalysts have been screened for the double-asymmetric hydrogenation of 2,6-di-(1-phenylethenyl)-4-m

16 Iridium-catalyzed asymmetric hydrogenation of 20 with the complex of [Ir(C

17 ex forms a highly effective catalyst for the asymmetric hydrogenation of a range of dehydroamino acid

18 A general asymmetric hydrogenation of a wide range of 2-alkyl- and

19 played excellent enantioselectivities in the asymmetric hydrogenation of a wide range of acyclic imin

20 f 50,000 catalyst turnovers per hour for the asymmetric hydrogenation of a wide variety of dehydro-al

21 inchona-modified Pt and Pd catalysts for the asymmetric hydrogenation of activated C horizontal lineO

22 Asymmetric hydrogenation of alkenes is one of the most w

23 Asymmetric hydrogenation of allylic dimethylcarbinamide

24 Rh-DuPhos-catalyzed asymmetric hydrogenation of alpha,beta-diamidoacrylates

25 oselective phosphine-nickel catalyst for the asymmetric hydrogenation of alpha,beta-unsaturated ester

26 chirally modified platinum catalysts for the asymmetric hydrogenation of alpha-activated ketones as a

27 of beta-amino acid derivatives (1a-c) using asymmetric hydrogenation of alpha-aminomethylacrylates (

28 d Pt catalysts are used in the heterogeneous asymmetric hydrogenation of alpha-ketoesters.

29 ld of an amine produced by iridium catalyzed asymmetric hydrogenation of an iminium salt.

30 se Ru catalysts thus gave the highest ee for asymmetric hydrogenation of aromatic ketones among all o

31 These Ru complexes were used for asymmetric hydrogenation of aromatic ketones in a highly

32 found to be new efficient catalysts for the asymmetric hydrogenation of arylated alpha,beta-unsatura

33 xes with 5-7 are efficient catalysts for the asymmetric hydrogenation of beta-substituted enamides an

34 Asymmetric hydrogenation of CI-1008 (pregabalin) precurs

35 The asymmetric hydrogenation of cyclic alkenes lacking coord

36 displayed excellent enantioselectivities in asymmetric hydrogenation of cyclic imines, affording bio

37 The asymmetric hydrogenation of dehydroamino acid derivative

38 complexes, which serve as catalysts for the asymmetric hydrogenation of di-, tri-, and tetrasubstitu

39 ination with [Rh(cod)2]BArF (1 mol %) in the asymmetric hydrogenation of dimethyl itaconate.

40 ins, were evaluated in the rhodium-catalyzed asymmetric hydrogenation of dimethyl itaconate.

41 ring the last few decades, rhodium-catalysed asymmetric hydrogenation of diverse alkene classes has e

42 rk's [Rh(COD)(2R,5R)-Et-DuPhos]BF4-catalyzed asymmetric hydrogenation of enamides with a variety of r

43 The catalyst shows exceptional reactivity in asymmetric hydrogenation of enamines and unhindered imin

44 These complexes were tested in asymmetric hydrogenation of functionalized olefins.

45 In the (S)-proline-mediated asymmetric hydrogenation of isophorone (IP) on supported

46 ave proven to be excellent catalysts for the asymmetric hydrogenation of ketones, giving reduction pr

47 count the early breakthroughs concerning the asymmetric hydrogenation of largely unfunctionalized ole

48 Iridium-catalyzed asymmetric hydrogenation of N-alkyl-2-alkylpyridinium sa

49 st decade on noble metal-based heterogeneous asymmetric hydrogenation of prochiral C horizontal lineO

50 The asymmetric hydrogenation of tetrasubstituted olefins pro

51 yl-alpha-amino acids and esters, through the asymmetric hydrogenation of tetrasubstituted olefins, so

52 In the second step, asymmetric hydrogenation of the ketone functionality in

53 ed pyridinium C-H arylation and Ir-catalyzed asymmetric hydrogenation of the resulting fused tricycli

54 The catalytic asymmetric hydrogenation of trisubstituted enol esters u

55 When they were used in the iridium-catalyzed asymmetric hydrogenation of unfunctionalized 1-aryl-3,4-

56 ere successfully applied in the Ir-catalyzed asymmetric hydrogenation of unfunctionalized alkenes wit

57 Homogeneous asymmetric hydrogenation of unprotected benzophenone N-H

58 Homogeneous asymmetric hydrogenation of unprotected N-H ketoimines 3

59 Asymmetric hydrogenation of unprotected NH imines cataly

60 re highly enantioselective catalysts for the asymmetric hydrogenation of various kinds of functionali

61 e complexes 1a-c were prepared and tested in asymmetric hydrogenations of a series of largely unfunct

62 ine analogue of Crabtree's catalyst "cat" in asymmetric hydrogenations of allylic amine derivatives o

63 -heterocyclic carbene oxazoline ligands 1 in asymmetric hydrogenations of arylalkenes.

64 rial review lessons learned from research on asymmetric hydrogenation on chirally modified noble meta

65 olefins were prepared and evaluated for the asymmetric hydrogenation reaction using novel N,P-ligate

66 ds were prepared using the iridium catalyzed asymmetric hydrogenation reaction.

67 Asymmetric hydrogenation routes to homologues of The Roc

68 phosphonation-olefination-rhodium-catalyzed asymmetric hydrogenation sequence for the urea.

69 scovery programs and endeavored to devise an asymmetric hydrogenation strategy to improve access to t

70 -alkylprolinols and prolines via a divergent asymmetric hydrogenation strategy.

71 tions used for catalyst preactivation in the asymmetric hydrogenation studies), the products are iden

72 the Heck reaction and subsequent successful asymmetric hydrogenation to afford alpha-hydroxyl esters

73 e lactone carbonyl group of 2 and subsequent asymmetric hydrogenation to generate the corresponding a

74 Asymmetric hydrogenation using catalyst precursor 36 on

75 An asymmetric hydrogenation was employed to set the C6 ster

76 pplications in highly efficient Ru-catalyzed asymmetric hydrogenations were explored.

77 e-derived phosphonate, followed by catalytic asymmetric hydrogenation, which proceeds with excellent

78 nols have been prepared in up to 97.8% ee by asymmetric hydrogenation with cationic rhodium Me-BPE or

79 the synthetic sequence involve (a) catalytic asymmetric hydrogenation with chiral DM-SEGPHOS-Ru(II) c

80 ids 7 and 13 derived from 5 or 11, underwent asymmetric hydrogenations with Burk's DuPHOS Rh(I)-based