ライフサイエンスコーパス: at the end of

1 /mL during treatment), which were maintained at the end of 1 year follow-up in these five patients.

2 ); five maintained this level of suppression at the end of 1 year follow-up.

3 s and newly established in an eighth patient at the end of 1 year follow-up.

4 Retinal imaging was obtained at the end of 1 year of glycemic control assessment.

5 nal in just 14 s with minor signal reduction at the end of 10000 cycles.

6 Endobronchial biopsies were performed at the end of 12 weeks.

7 based on pretreatment data and the findings at the end of 14-day antibiotic treatment accurately pre

8 ase of transdermal and combination of routes at the end of 15th week when compared to controls.

9 The cumulative risk at the end of 2 years for each outcome was 24.4%, 4.0%,

10 an forests were younger than 30 years of age at the end of 2012.

11 nning of 2010 to 39 (71%) of 55 centres open at the end of 2014.

12 an extraordinary increase in air temperature at the end of 2015.

13 er a phosphoryl or a phosphate group was 357 at the end of 2016.

14 s retention was associated with prevalent VS at the end of 36 months (adjusted prevalence ratio 3.12;

15 ] were considered to have hair preservation) at the end of 4 cycles of chemotherapy by a clinician un

16 iod was 4 weeks, and animals were sacrificed at the end of 4 weeks.

17 ts with tonal and non-blast induced tinnitus at the end of 6 (24.3% vs. 2%, p = 0.05) and 12 weeks (3

18 At the end of 6 months, the mean BCVA was significantly

19 ent, followed by development of ER autophagy at the end of 6 weeks of treatment.

20 the 6-minute walk test, made available only at the end of 7 days.

21 Regarding new bone formation, at the end of 8 weeks, DOX (61.11%) also had the highest

22 45) of cocaine-dependent individuals scanned at the end of a 30-day residential treatment programme.

23 : 1) Insertion in the mid-region or addition at the end of a myofibril; 2) Sequential addition with a

24 At the end of a three-enzyme cascade, ubiquitin ligases

25 nd Trp residues served as donor and acceptor at the ends of a long loop between helices I and II, and

26 es that are achievable by two remote parties at the ends of a quantum channel, without restrictions o

27 At the end of ageing, wines stored at 6 degrees C had th

28 ysis in Cerebral Infarction score of 2b or 3 at the end of all endovascular procedures.

29 Before, immediately at the end of and 12 and 22 hours after hemorrhagic shoc

30 ages; the number of remaining platelet units at the end of any day stays above 10 in our model during

31 ative hypoxia and recovered to normal levels at the end of blood vessel formation.

32 ent with the proposed role of M2 in scission at the end of budding.

33 Telomeres are found at the end of chromosomes and are important for chromoso

34 s consist of tandem repeats of DNA sequences at the end of chromosomes, preventing chromosomal fusion

35 Telomeres, the protective caps at the ends of chromosomes, shorten in response to oxida

36 Typically, Rho promotes termination at the end of coding sequences, but it can also terminat

37 Decile of school grades at the end of compulsory education (range, 1-10, with 1

38 records beginning in 2001, and school grades at the end of compulsory education were collected for al

39 ssion, and terminal differentiation of cells at the end of culture.

40 At the end of development, the respiratory and ethylene

41 oplet size emulsion contained undigested oil at the end of digestion, whereas an almost complete hydr

42 s have still no evidence of disease activity at the end of DMF treatment.

43 Plasma samples were obtained at baseline and at the end of each 4-wk period in the fasting state for

44 PaO2 was measured at the end of each condition and QIPAVA was assessed usi

45 d changes in the pitch angle (wing rotation) at the end of each half-stroke, and they are therefore r

46 tational mechanisms that occur when pitching at the end of each half-stroke.

47 neously measuring the (TTAGGG)n tract length at the end of each large telomere-terminal DNA segment.

48 At the end of each period, fractional clearance rates (F

49 Fasting blood samples were collected at the end of each sodium intervention.

50 At the end of each study week, spirometry was performed

51 ks, guided solely by delayed, phasic rewards at the end of each trial.

52 nducibility of any sustained tachyarrhythmia at the end of EAM procedure were identified as independe

53 At the end of every growing season, the aerial tissues s

54 is used by arthropods to shed their cuticle at the end of every molt.

55 d fat and water separation was also acquired at the end of expiration for PET attenuation correction

56 and the wine samples taken in the middle and at the end of fermentation.

57 as observed only in past and current smokers at the end of follow-up [HR=1.00 (95% CI: 0.94, 1.07) ba

58 The mean (SD) age of children at the end of follow-up was 6.24 (3.19) years.

59 Results At the end of follow-up, 36% of patients (93 of 256) die

60 At the end of follow-up, 68% of PEPT2*1*1 carriers had a

61 At the end of follow-up, 70 patients were alive, with 67

62 At the end of follow-up, graft survival was 77% (10/13).

63 ded 2910 persons with nonaffective psychoses at the end of follow-up, of whom 704 had narrowly define

64 At the end of follow-up, the incidence rate of P. vivax

65 At the end of follow-up, there was a trend for mean VA f

66 ood pressure monitoring, and polysomnography at the end of follow-up.

67 n Questionnaire (NEI VFQ-25) at baseline and at the end of follow-up.

68 measurable residual disease (MRD) detection at the end of induction chemotherapy in pediatric patien

69 s to evaluate minimal residual disease (MRD) at the end of induction treatment with chemoimmunotherap

70 Investigator-assessed overall response at the end of induction was 84.9% (95% CI 79.2-89.5) in

71 To examine response kinetics at the end of induction, we log-transformed the absolute

72 med complete response, and partial response) at the end of induction.

73 Results MRD was log normally distributed at the end of induction.

74 e attractive to 50% of the female sand flies at the end of infection compared to before infection and

75 e attractive to 75% of the female sand flies at the end of infection.

76 At the end of infusion, the estimated (89)Zr-trastuzumab

77 8.6 is estimated to result in a negative GMI at the end of isavuconazole therapy.

78 wth rate and the mechanisms that stop growth at the end of juvenile growth.

79 ded shortening velocity (V0 ) is already set at the end of latency relaxation (LR), approximately 10

80 The role of trust in health care at the end of life has been acknowledged as crucial for

81 dical treatment or palliative treatment only at the end of life may influence patient decisions.

82 euromuscular-blocking agents be discontinued at the end of life or when life support is withdrawn.

83 Society's focus at the end of life should be on efforts to address suffe

84 herapy or have intensive care unit admission at the end of life, and were more likely to enroll in ho

85 At the end of life, patients with cardiovascular disease

86 fering in patients with advanced disease and at the end of life.

87 erapy or be admitted to intensive care units at the end of life.

88 diseases and disability until a brief period at the end of life.

89 lliative care consultations may be underused at the end of life.

90 an-assisted suicide should be a legal option at the end of life.

91 o improving care for patients throughout and at the end of life.

92 ten receive high-intensity (HI) medical care at the end-of-life (EOL).

93 mary care providers to patients and families at the end-of-life in the intensive care unit.

94 Telomerase maintains telomere length at the ends of linear chromosomes using an integral telo

95 ment (n) during V0 shortening imposed either at the end of LR or at the plateau of the isometric cont

96 hortening and, during V0 shortening starting at the end of LR, is 1-4.

97 m per hs) and, when V0 shortening is imposed at the end of LR, n can be as low as 1-4.

98 half and end of alcoholic fermentation, and at the end of malolactic fermentation.

99 oplast-like radial microtubule arrays (RMAs) at the end of meiosis II.

100 ntestinal epithelial stem cell proliferation at the end of metamorphosis (for the few that survive th

101 f daughter chromosomes into a single nucleus at the end of mitosis is essential for genome stability.

102 ytokinesis cleaves a cell into two daughters at the end of mitosis, and must be spatially coordinated

103 Type 1 nodes assemble in two phases-a burst at the end of mitosis, followed by steady increase durin

104 At the end of neonatal exposure, THS-treated male and fe

105 lhycca1 exhibited an inhibition of growth at the end of night and growth rose earlier after dawn,

106 th reduced pathogen burdens at distant sites at the end of observation.

107 A single subconjunctival injection of XG-102 at the end of ocular surgery is noninferior to dexametha

108 47) or 900 mug (n = 48) or placebo (n = 50) at the end of ocular surgery.

109 f the D1-D2 linker, a 22-amino acid peptide, at the end of p97 N-D1 truncate has been shown to activa

110 , and CDK1 promotes efficient SC destruction at the end of prophase I to ensure faithful inheritance

111 res and/or elevated minimal residual disease at the end of remission induction therapy.

112 reased to 66 and 144 peptides, respectively, at the end of ripening.

113 At the end of scheduled feeding, c-Fos brain mapping rev

114 ased phosphorus solubilized by acidification at the end of second cycle, however, it also decreased t

115 Before, at the end of shock and every 12 hours of resuscitation,

116 g sites and was bound to GLIC asymmetrically at the end of simulations.

117 At the end of storage time of the classical and probioti

118 peroxide values (13-539meqO2/kgfat) measured at the end of storage, and the exponential increase of h

119 ptides from the four caseins were identified at the end of storage.

120 and 9% (FRAP), respectively for CHE samples at the end of storage.

121 was found to be 16% less than treated juice at the end of storage.

122 data for patients followed 1, 2, or 3 years at the end of study enrollment.

123 es (not all extinction has occurred suddenly at the ends of such intervals); second, to separate out

124 ar (YOY) and adult brown trout attained 100% at the end of summer, while seasonal population decay wa

125 interface fluid volume, area, and thickness at the end of surgery detected with iOCT are associated

126 mmatory genes, as observed in biopsies taken at the end of surgery, as well as the serum cytokines, s

127 iodine) or group 2 (without povidone-iodine) at the end of surgery.

128 r the sliding noose of the adjustable suture at the end of surgery.

129 At the end of surveillance, 36.7% (CI, 34.4% to 38.9%) o

130 lar activity, 7.4 +/- 1.9 GBq total activity at the end of synthesis (n = 17), and more than 99% radi

131 that the values for HMW multimers and CT-ADP at the end of TAVR were each associated with mortality a

132 e approximately 20 p.p.m.v. overshoot in CO2 at the end of Termination 2 (T2) approximately 129 ka wa

133 currence and off antiarrhythmic drug therapy at the end of the 12-month follow-up.

134 hose levels in respective sham-RDN rats, and at the end of the 12-week study, rats in both strains ha

135 4 per thousand decrease in delta(15)N values at the end of the 1970's corresponds to a strong reducti

136 d sexual transmission, and sporadic clusters at the end of the 2013-2016 epidemic have prompted recom

137 rican Society of Nephrology (ASN) membership at the end of the 2015-2016 academic year in conjunction

138 rface could be under moderate or severe risk at the end of the 21(st) century under the middle and hi

139 At the end of the 21st century, modeled GPP mainly incre

140 during optimised VIM or VO lead stimulation at the end of the 3 months.

141 uals with or without P. falciparum infection at the end of the 6-month dry season were identified by

142 MMP2 and MMP9 were measured at baseline and at the end of the 6-week study period.

143 through critical interactions with proteases at the end of the A-sheet.

144 The current at the end of the breakthrough phase, lasting on average

145 ely large net increases, with the net change at the end of the century ranging from 3.0% (-3.0 to 9.3

146 o free fatty acids and glycerol, which elute at the end of the chromatogram after the analytes, avoid

147 ed intakes from 7DDRs and the SFFQ completed at the end of the data-collection period ranged from 0.3

148 he chondrichthyan response to the extinction at the end of the Devonian period.

149 ers area under the curve (AUC) concentration at the end of the dosing interval (AUCtau) for elvitegra

150 At the end of the double-blind phase, the least squares

151 pressure, two methods of capturing the ions at the end of the drift tube have been developed, Interm

152 ng the vesicle fusion to the plasma membrane at the end of the exocytosis process.

153 usually the reconstitution success is tested at the end of the experiment and often by an additional

154 meters were found, nor was the energy intake at the end of the experiment different between the 3 con

155 At the end of the experiment some metabolites will have

156 ioactive compounds was also delayed although at the end of the experiment the content of bioactive co

157 Speciation in the solid phase was determined at the end of the experiment using X-ray absorption near

158 At the end of the experiment we assessed the fitness and

159 At the end of the experiment, summation operatorPOP conc

160 sed although they only exploit data observed at the end of the experiment.

161 [0.9-6.2] vs 6.9 [4.8-9.8] ng/mL; p < 0.05) at the end of the experiment.

162 Retinal detachment (RD) often occurs at the end of the first decade of life or later.

163 e marrow sample at diagnosis and 82 patients at the end of the first line of treatment (EOT).

164 t mother who had a febrile illness with rash at the end of the first trimester of pregnancy while she

165 follow up period (T2) (mean 15.3 years), and at the end of the follow-up period (T3) over 25 years.

166 Food waste at the end of the food value chain (households and food

167 mic funnel and opening of a hydrophobic gate at the end of the funnel.

168 f the surface Env subunit (SU) and the other at the end of the fusion peptide region (L378S)-were fou

169 e heterogeneity of the weight of individuals at the end of the game is higher when sensitivity and vi

170 Emulsion particle sizes at the end of the gastric phase were directly associated

171 es to the physiologic downregulation of BCL6 at the end of the GC reaction.

172 predicted, mean size of age 1 and older fish at the end of the growing season increased across years

173 avonoid contents (TF) decreased by about 50% at the end of the in vitro GID.

174 At the end of the incubation, the changes in the total a

175 e group (n = 151) showed a higher urinary pH at the end of the infusion than patients randomized to t

176 es after the first operation and in 12 (92%) at the end of the intervention.

177 (beta-CM7) was detected (0.187-0.858mgL(-1)) at the end of the intestinal digestion in all untreated

178 However, at the end of the intestinal stage, acrylamide values we

179 lting history of the Fennoscandian Ice Sheet at the end of the last deglaciation ( approximately 13,2

180 es of human response to the changing climate at the end of the last glacial in Northern Europe.

181 , at first slowly from about 7,300 to 9,800 (at the end of the last glacial maximum about 15,000 YBP)

182 , at least concerning maternal lineages, was at the end of the Late Glacial, due to major expansions

183 ilament under zero load, V0 ) is already set at the end of the latency relaxation (LR) preceding isom

184 egradation, with maximum levels accumulating at the end of the long night.

185 At the end of the multistep transcription process, the e

186 particular, an ionic concentration gradient at the end of the nanopipette, generates an ionic curren

187 hing T-cycle, like the inhibition in lhycca1 at the end of the night, indicating that it is due to pr

188 At the end of the observed reaction sequence, hExo1 rese

189 unique water-mediated interaction with Tyr63 at the end of the para-aminobenzoate channel.

190 iti, India suggest that the nickel anomalies at the end of the Permian were a worldwide phenomenon.

191 vival, and pharmacokinetics will be reported at the end of the phase 2 portion of the trial.

192 te Glacial, a period of climatic instability at the end of the Pleistocene.

193 dy endpoints were technical success assessed at the end of the procedure and device success 30 days a

194 been noted when bivalirudin is discontinued at the end of the procedure, which is perhaps related to

195 increased successful revascularization rate at the end of the procedure.

196 differences in the number of tubers obtained at the end of the process.

197 rotation of the C domain (up to 30 degrees ) at the end of the relatively immobile interdomain linker

198 tor eliminated, as expected, injury recorded at the end of the reperfusion phase but failed to elimin

199 The primary outcome, measured at the end of the school term, was the mean score on a t

200 icantly efficacious until data became sparse at the end of the season.

201 -Na(3-x)Sb is converted to crystalline Na3Sb at the end of the second discharge.

202 At the end of the second dry season, 3 groups of asympto

203 s performed before treatment and after 2 wk, at the end of the second week of first cycle carboplatin

204 At the end of the selection and collection processes, 5

205 cell losses (those which are unaccounted for at the end of the separation), and cost.

206 durum wheat, with a maximum at 50 degrees C at the end of the storage period (94%).

207 nt days decreased to 0.48 (IQR, 0.0-1.4) and at the end of the study decreased to 0.18 (IQR, 0.0-0.59

208 e time of transplantation (listed only), and at the end of the study period (listed or transplant).

209 At the end of the study period, complete clearance (ie,

210 ith 21.6% +/- 9.3% seen in the control group at the end of the study period.

211 The median age of individuals at the end of the study was 22.2 years (interquartile ra

212 period, P = .04), and the cumulative effect at the end of the study was estimated to be -30.9%, (95%

213 At the end of the study, 1520 (83.1%) of the original sa

214 At the end of the study, 80.6% of participants reported

215 At the end of the study, 83% of patients treated with >/

216 At the end of the study, all of the rats were euthanized

217 At the end of the study, echocardiography was repeated,

218 At the end of the study, mice in the control group showe

219 At the end of the study, participants taking KCl had sta

220 At the end of the study, the suitability of this new pro

221 The survival rate was 73% (n = 242) at the end of the study.

222 General well-being score was increased at the end of the study.

223 nd fMRI scans were conducted at baseline and at the end of the study.

224 nd then colonized with CONV-R gut microbiota at the end of the suckling-weaning transition.

225 OBSERVATION: Intraocular pressure (IOP) at the end of the surgery, immediately after filling the

226 ain data before and after each procedure and at the end of the surgical day.

227 ain data before and after each procedure and at the end of the surgical day.

228 ere significantly more likely to be retained at the end of the taper compared with clonidine particip

229 At the end of the target article, Keven & Akins (K&A) pu

230 ation of therapy (time 1 of therapy: T1) and at the end of the therapy (Time 2: T2).

231 All available structures of these enzymes at the end of the transposition reaction, including Mu,

232 r scores indicating better quality of life), at the end of the treatment period at week 14, after the

233 11.6 hours, and the median oxygen saturation at the end of the treatment period was 99% among patient

234 r significantly among the three study groups at the end of the treatment period, with mean scores of

235 number of doublecortin-positive neuroblasts at the end of the treatment period.

236 At the end of the treatment protocol, we assessed cardia

237 Median follow-up at the end of the trial on Nov 5, 2014, was 49.6 months

238 At the end of the trial, the use of allergic rhinoconjun

239 performed at baseline, week 24, yearly, and at the end of the trial.

240 ere collected in the first 3 d on campus and at the end of the year.

241 mediate dimerization and activation of Torso at the ends of the Drosophila embryo.

242 d to two spin-(1/2) quasiparticles localised at the ends of the macroscopic wire.

243 ion of the growing peptide chain, and clamps at the ends of the mRNA tunnel with three proteins ensur

244 isotropy of force generation by myosin heads at the ends of the myosin clusters.

245 tified plasma metabolites in 73 participants at the end of their high- and low-sodium interventions a

246 -sodium interventions and in 46 participants at the end of their high- and medium-sodium intervention

247 ommon eiders (Somateria mollissima) (N = 54) at the end of their incubation-related fasting.

248 induced by HIV infection have functional GJs at the ends of their membrane extensions and that TNTs m

249 s) with psychological therapy versus control at the end of therapy for patients with quiescent diseas

250 ntain viable tumor, whereas residual lesions at the end of therapy may constitute eradicated tumor/sc

251 Furthermore, 8 of 38 (21%) had stable IFD at the end of therapy without progression of disease, an

252 At the end of therapy, the model significantly (p = .000

253 t baseline, before each cisplatin cycle, and at the end of therapy.

254 nd follow-up scans after 3 cycles as well as at the end of therapy.

255 sh the exposure necessary for GMI negativity at the end of therapy.

256 nts receiving DAAs therapy prior, during and at the end of therapy; (2) evaluate PROs of Interferon-f

257 tendon cells at myotendinous junctions, form at the ends of these muscle islands, suggesting that myo

258 With this exclusion, T2, the tension at the end of this period, rises with an increase of str

259 gain, even when the position-dependent gain at the end of training was significantly greater.

260 ge numbers because of a crisis in confidence at the end of training.

261 nary arterioles were evaluated in all groups at the end of training.

262 ion and the removal of RNA polymerase (RNAP) at the ends of transcription units.

263 At the end of treatment (14 days for the consecutive-day

264 The primary outcome was ART adherence at the end of treatment (4 month assessment) assessed vi

265 H-I was inferior to CBT in reducing OBE days at the end of treatment (adjusted effect, 1.63; 95% CI,

266 e antibody (anti-HBs) titres above 10 mIU/mL at the end of treatment (five had maximum anti-HBs conce

267 The primary outcome was hot flash score at the end of treatment (week 12), calculated as the fre

268 7, and received a bone marrow MRD assessment at the end of treatment according to the international h

269 clinical response, defined as clinical cure at the end of treatment and no recurrence within 30 days

270 ine yielded a 40%-50% decrease in tumor mass at the end of treatment as compared with control mice (P

271 The disease activity score was decreased at the end of treatment in 20% (2 of 10) of the placebo

272 ge due to radiation therapy and their values at the end of treatment may be indicators of tumor respo

273 prognostic, while texture-strength measured at the end of treatment significantly stratified high- a

274 articipants maintained the gains they showed at the end of treatment through the 12-month follow-up (

275 articipants maintained the gains they showed at the end of treatment through the 12-month follow-up,

276 HAP's superiority over EUC at the end of treatment was largely stable over time and

277 CAP's superiority over EUC at the end of treatment was largely stable over time and

278 Mean HF scores at the end of treatment were 15.36 in the acupuncture gr

279 The primary endpoints assessed at the end of treatment were the safety and tolerability

280 At the end of treatment, 16% of participants in the acup

281 At the end of treatment, a new endoscopy was performed.

282 weeks had normal alkaline phosphatase values at the end of treatment, based on a central laboratory U

283 At the end of treatment, cognitive function, metabolic p

284 At the end of treatment, morphological and biochemical a

285 Clinical outcome assessments were made at the end of treatment, test of cure, and follow-up vis

286 Results At the end of treatment, the prevalence of any degree of

287 Regardless of the viral clearance at the end of treatment, there was a significant improve

288 patients had suppressed HBV DNA (<10 IU/mL]) at the end of treatment, which was maintained by seven p

289 d at baseline, after 4 cycles of R-CHOP, and at the end of treatment.

290 The primary outcome was HF score at the end of treatment.

291 ntly higher during the treatment period than at the end of treatment.

292 ng memory task were assessed at baseline and at the end of treatment.

293 ose who relapsed was ribavirin concentration at the end of treatment.

294 atment, with nine remaining HDV RNA negative at the end of treatment; seven of these patients remaine

295 g asthma symptoms or using asthma medication at the end of trial (odds ratio = 0.66, P < .036), durin

296 Cataracts were evaluated at the end of week 2 (postpartum day 14) when the rat pu

297 ing dyslipidemia only significantly occurred at the end of week 24.

298 days 15 to 30), and the rats were sacrificed at the end of week 4.

299 Use of osteoporosis medication was higher at the end of year 1 in the screening group compared wit

300 t 1 year, with some loss in the visual gains at the end of year 2 that was not related to loss of exu