ライフサイエンスコーパス: at the site of

1 Bacterial division initiates at the site of a contractile Z-ring composed of polymeri

2 We hypothesize that the creation of a flap at the site of a leading strand discontinuity could, in

3 Studies examining skin O2 changes at the site of a lesion are limited.

4 ble to induce a pro-regenerative environment at the site of a subcutaneous implant.

5 erminal nerve regeneration was observed only at the sites of ablation as early as 60 days and continu

6 Subretinal cleft specifically occurred at the site of absent photoreceptors.

7 At the sites of accumulation, exosomes were taken up by

8 These concentrations, evaluated at the site of action, the brain, have been correlated w

9 ker components to achieve a desired response at the site of action, which imparts nanogels the abilit

10 roach for concentrating toxic chemotherapies at the site of action.

11 anding of the local exposure to unbound drug at the site of action.

12 both the local neuronal population activity at the site of activation and the propagation to downstr

13 Additionally, iNKT levels are higher at the site of active oesophageal eosinophilic inflammat

14 Microglia and macrophages accumulate at the sites of active demyelination and neurodegenerati

15 endoplasmic reticulum (ER) to be transported at the site of activity.

16 taining intravenously injected nanoparticles at the site of acute myocardial infarction in a rat mode

17 tion and plasmin inhibition system assembled at the site of acute pulmonary emboli in vivo.

18 , revealed the persistence of injected cells at the site of administration.

19 Marked (18)F-NaF uptake occurred at the site of all carotid plaque ruptures and was assoc

20 Eosinophils accumulate at the site of allergic inflammation and are critical ef

21 tory cells, allowing for paracrine signaling at the site of an infection.

22 the first and most numerous cells to arrive at the site of an inflammatory insult and are among the

23 gonadal tissues through their juxtaposed BMs at the site of anchor cell (AC) invasion in C. elegans.

24 rania associated with Acheulean handaxes are at the sites of Arago, Atapuerca Sima de los Huesos (SH)

25 We demonstrate that local monomer depletion at the site of assembly negatively impacts the network g

26 Papilla formation at the site of attack is essential for preinvasive immun

27 ion mutant background, with callose deposits at the site of attempted fungal penetration.

28 t occurs in response to pathogen recognition at the site of attempted invasion.

29 G, has not been analyzed in the periphery or at the site of autoimmune disease.

30 ulatory rather than effector T-cell response at the site of autoimmunity, supporting IFIH1 expression

31 was investigated using microbiology methods at the sites of bacterial infections.

32 ll as MBP-1, induced vimentin polymerization at the site of bacterium-host cell contact.

33 We isolated tissues at the site of blastogenesis onset and from the same epi

34 TRUME technique can create an optical focus at the site of bubble destruction with a size of approxi

35 The presence of HA and NP at the site of budding depends upon the coexpression of

36 stone refits suggest that breakage occurred at the site of burial.

37 e presence of a functional group is required at the site of C-C bond formation.

38 those conditions (i.e. low CO2 availability at the site of carboxylation and high temperature) induc

39 organization to nhTMEM16, except for changes at the site of catalysis.

40 system utilizing appropriate vascularization at the site of cell implantation that results in volumet

41 ata show that BCV controls viral replication at the site of challenge and reduces viral dissemination

42 the control of viral replication in the gut at the site of challenge that was associated with lower

43 ck-linked iLOV gene contains eight triazoles at the sites of chemical ligation, and yet is fully bioc

44 in animal models, abundant GM-CSF production at the sites of CNS inflammation suggests that GM-CSF co

45 99m)Tc-rCR2), which specifically detects C3d at the site of complement activation.

46 The VS forms at the site of contact between an infected cell and an u

47 ell polarization and localized virus budding at the site of contact that facilitates cell-cell spread

48 characterized by an intensely pruritic rash at the site of contact with allergens like poison ivy or

49 ation, and attenuated global gene activation at the site of cutaneous VZV antigen challenge compared

50 adD is mediated through interaction with SSB at the site of damage.

51 mes and concentration of DNA-repair proteins at the site of damage.

52 This effect is even more pronounced at the site of damage.

53 an neural progenitor cells were transplanted at the site of damage.

54 ignancies suggests that infiltrating T cells at the site of disease are crucial to tumor control.

55 ained from studying M. tuberculosis immunity at the site of disease during HIV infection.

56 At the site of disease, IL-27 was more strongly expresse

57 econstitution of potent therapeutic activity at the site of disease, sparing healthy tissues.

58 oles becomes mirrored at new poles initiated at the site of division.

59 CBX8 protein rapidly accumulates at the sites of DNA damage within 30 s and progresses to

60 hat assembles on single-stranded DNA (ssDNA) at the sites of DNA damage.

61 air and signaling molecules mobilize rapidly at the sites of DNA double-strand breaks.

62 s (HSV)-infected cells, ND10 bodies assemble at the sites of DNA entering the nucleus after infection

63 e retention of p53 binding protein 1 (53BP1) at the site of DSBs.

64 Recently completed excavations at the site of El Palenque in Mexico's Valley of Oaxaca

65 n a) the product of the orbital coefficients at the sites of electrode attachment, and b) the MO ener

66 Myo1p concentrates at the site of endocytosis and initiates a zone of actin

67 adenosine in PMN activation and recruitment at the site of endothelial injury.

68 MI was measured at the site of esophagitis and at 2, 5, and 10 cm above

69 hances polar secretion by tethering vesicles at the site of exocytosis.

70 f Rubisco allows for high-CO2 concentrations at the site of fixation, providing an advantage in low-C

71 ent reduced microglial/macrophage activation at the site of focal inflammatory lesions, presumably by

72 cted poplar leaves accumulated significantly at the site of fungal infection in the lower epidermis.

73 of cytological structures known as chiasmata at the sites of genetic crossovers (COs).

74 d by thrombotic arterial occlusion localized at the site of high-risk atherosclerotic plaques, of whi

75 on with the plasma membrane could be favored at the sites of high density of target cells, such as ly

76 tpost, associated with the early Viru state, at the site of Huaca Prieta in the Chicama Valley, locat

77 surround ubiquitinated cargoes to trap them at the site of ILV budding while the cargoes undergo deu

78 e draining lymph node, but not in the tissue at the site of immunization are important for vaccine-in

79 lymph node macrophages, but not macrophages at the site of immunization, are essential for the gener

80 cines results in accumulation of macrophages at the site of immunization, which suggests that macroph

81 ve molecules to promote enhanced integration at the site of implantation.

82 lammation and RhoA activation occur in rAION at the site of infarction.

83 tional model that combines what is occurring at the site of infection (e.g., lung) at a single granul

84 Furthermore, Eo-MDSC accumulated at the site of infection and exerted a potent immunosupp

85 They are found only at the site of infection and not in other peripheral sit

86 rm that releases its antibiotic payload only at the site of infection and only in the presence of the

87 ential to continuously replenish the T cells at the site of infection and prevent attrition and funct

88 f pathways that directly impact the pathogen at the site of infection and subsequent pathogen clearan

89 y skewed the CHIKV-induced cytokine response at the site of infection at multiple times postinfection

90 he first time, the changes in the microbiota at the site of infection by a parasitic helminth (hookwo

91 spatial and temporal dynamics of antibiotics at the site of infection can aid in reducing the design

92 program maximal secondary effector responses at the site of infection during heterosubtypic challenge

93 MDSCs were identified at the site of infection in the lung in disease-resistan

94 ) after initiation of antiretroviral therapy at the site of infection is poorly understood.

95 Because initial swarming of neutrophils at the site of infection occurs within minutes, rather t

96 The first cells at the site of infection or inflammation are neutrophils

97 -induced termination of neutrophil migration at the site of infection permits a smooth transition to

98 Biofilm formation at the site of infection reduces antimicrobial susceptib

99 argely of the Vgamma4+ subset and accumulate at the site of infection subsequent to an initial Vgamma

100 We identified a population bottleneck at the site of infection that significantly altered the

101 ch induces type-2 helper T cells (Th2 cells) at the site of infection to produce IL-13, thereby contr

102 osal-associated invariant T cells accumulate at the site of infection with organisms producing (E)-4-

103 assumed that inhibition of bacterial fitness at the site of infection without directly affecting viab

104 esized that innate cellular immune responses at the site of infection would correlate with disease ou

105 of infected SM/J, recruited less efficiently at the site of infection, and displayed blunted oxidativ

106 e rate of proliferation of Th1/Th2 responses at the site of infection, efficiency at which immune res

107 tiate or withhold a proinflammatory response at the site of infection, generating a microenvironment

108 Although T cells arrive at the site of infection, they do not provide sterilizin

109 anges in the blood and lymphatic vasculature at the site of infection.

110 ding of the physiological state of pathogens at the site of infection.

111 iting the ability of AM to clear neutrophils at the site of infection.

112 eoclastogenesis of the uninfected precursors at the site of infection.

113 zed accumulation within the microenvironment at the site of infection.

114 of S100 protein-mediated metal sequestration at the site of infection.

115 rides as a nutrient source for proliferation at the site of infection.

116 ytic cells, allowing the bacteria to persist at the site of infection.

117 nd suppress antiviral effector cell activity at the site of infection.

118 nes for the characteristic pustule formation at the site of infection.

119 llular proteolytic activity of P. gingivalis at the site of infection.

120 l protection against pathogen entry directly at the site of infection.

121 ells to rapidly express CD69 and be retained at the site of infection.

122 icient mice have reduced T cell accumulation at the site of inflammation and reduced ILC2-dependent i

123 wn, endogenous Tregs in order to enrich them at the site of inflammation and tissue destruction.

124 Pain hypersensitivity at the site of inflammation as a result of chronic immun

125 ad been speculated that sIL-6R was generated at the site of inflammation by shedding from neutrophils

126 acking IRF5 accumulate far fewer neutrophils at the site of inflammation due to the reduced levels of

127 ory T cell polarization in vitro and in vivo at the site of inflammation in the lamina propria.

128 Treg subversion of effector T cell functions at the site of inflammation to restore normal tissue hom

129 kocytes attach to vascular endothelial cells at the site of inflammation via a series of intercellula

130 y, increased migration of inflammatory cells at the site of inflammation, and a significant increase

131 ty and contribute not only to O2 deprivation at the site of inflammation, but also alter many of thei

132 lation was highly specific to pathogenic IgG at the site of inflammation, driven by local platelet re

133 E4), and prostaglandin (PG) E2 are generated at the site of inflammation, it is not known whether cro

134 mune responses and IL-5 and IL-13 production at the site of inflammation.

135 s enhanced, altering immune cell recruitment at the site of inflammation.

136 ival of IL-2-producing adaptive immune cells at the site of inflammation.

137 ls the innate effector function of Th2 cells at the site of inflammation.

138 ignificant increase in the number of E. coli at the sites of inflammation in patients with UC, which

139 he ring increases while net cortical tension at the site of ingression decreases throughout constrict

140 ) CXCR5(+) PD1(hi) TFH were largely retained at the site of initial activation with little spillover

141 re of innate immune responses to control HIV at the site of initial mucosa infection.

142 al niches, it is imperative to study viruses at the site of initial replication.

143 These data suggest that intervention at the site of initial replicative expansion can delay t

144 usually results in the formation of a depot at the site of injection (SOI), which hinders the self-d

145 the LNP-encapsulated mRNA translated locally at the site of injection for up to 10days.

146 tion as peak Eulerian circumferential strain at the site of injection improved with MSCs (-4.9; 95% C

147 nderwent screening MRI to look for infection at the site of injection of contaminated methylprednisol

148 of mice, hPSC-derived V2a cultures survived at the site of injection, coexpressed NeuN and VGlut2, e

149 n of type I IFN and IFN-stimulated responses at the site of injection, concurrent with the preliminar

150 This allows the injected material to remain at the site of injection, until transcutaneous irradiati

151 7-expressing Ly6C(hi) inflammatory monocytes at the site of injection, upregulation of IFN-regulated

152 ncreases the penetrance of sarcoma formation at the site of injection, which is dependent on its cogn

153 tologically, with formation of muscle tissue at the site of injection.

154 significantly lower levels of IFN-alpha/beta at the site of injection.

155 acilitated efficient transduction of the CNS at the site of injection.

156 A dark clot formed at the site of injury in most species tested, including

157 ix component that is predominantly expressed at the site of injury in order to secure host tissue col

158 ed neutrophils on vascular endothelial cells at the site of injury may be a useful means of directly

159 mation and have an effect on the homeostasis at the site of injury or acute inflammation.

160 These remodeling events require activity at the site of injury, axon-to-soma signaling, and trans

161 ectin (FN) and then in situ FN are deposited at the site of injury.

162 tically digests CSPGs, which are upregulated at the site of injury.

163 the representation of microglia/macrophages at the site of injury.

164 during an ischemia/reperfusion (I/R) episode at the site of injury.

165 may explain why some patients develop a STS at the site of injury.

166 and the presence of citrullinated histone H3 at the site of injury.

167 is loss of myelin, creating conduction block at the site of injury.

168 trigger components of the inflammasome, both at the site of inoculation and at early sites of distal

169 bited enhanced induction of disease symptoms at the site of inoculation but reduced spread through th

170 at this position exhibited reduced swelling at the site of inoculation with a concomitant decrease i

171 individuals in the absence of obvious trauma at the site of inoculation.

172 Bs2 exhibited reduced water-soaking symptoms at the site of inoculation.

173 ces double-strand breaks (DSBs) specifically at the sites of integration, and it permits the dynamics

174 odels, expression of alpha-synuclein mutated at the site of interaction with dopamine prevented dopam

175 specific opsonic antibodies are not present at the site of interaction.

176 ct and confine drug release spatiotemporally at the site of interest with high specificity.

177 Immunization at the site of intradermally administered CGRP led to a

178 hospholipase D2 drives deposition of MT1-MMP at the site of invadopodia formation and is critical for

179 The most common acute effect was pain at the site of irradiation (two patients in the 4 Gy gro

180 straints on actin bundle retrograde movement at the site of lamella, such that actin bundle movement

181 l (PMN) activation leading to their adhesion at the site of laser-induced endothelial injury, a neces

182 (5) LV lead placement at the site of latest LV activation is desirable.

183 asipetal auxin transport in the SAM L1 layer at the site of leaf initiation, a process that continues

184 artner contains a lysine or arginine residue at the site of ligation.

185 body against LG1, we reveal LG1 accumulation at the site of ligule formation and in the axil of devel

186 At the site of LRP detected by NIRS in a cohort of pre-e

187 the presence or absence of neointimal tissue at the site of LRP detected by NIRS, intravascular ultra

188 At the site of LRP, intravascular ultrasound found no ne

189 1 levels are posttranscriptionally repressed at the site of maximum auxin accumulation at the root ti

190 nnexin A6 orchestrates a repair zone and cap at the site of membrane disruption.

191 t the assembly of productive SNARE complexes at the sites of membrane fusion.

192 -PEG4-LLP2A showed high uptake of the probes at the site of metastasis, correlating with the biolumin

193 e complex is implicated in protein synthesis at the site of microtubule assembly.

194 Besides changes in the hydration pattern at the site of modification, a slight opening of the hm(

195 ion of biphasic ferrogel scaffolds implanted at the site of muscle injury resulted in uniform cyclic

196 c acids occurs in a distinct protein complex at the site of nascent cell wall addition.

197 nce microscopy showed the localization of WH at the site of nascent DNA synthesis along with other re

198 t vesiculation and plasma membrane enclosure at the site of new disc formation are artifacts of tissu

199 surface of the patient contralateral to and at the site of nodal (18)F-FDG uptake were acquired usin

200 e of homology-directed DNA repair mechanisms at the site of nuclease action.

201 on for height growth with winter temperature at the site of origin.

202 were correlated with temperature and aspect at the sites of origin of the plants, while the amplitud

203 ermediate states of photosystem II catalysis at the site of oxygen production.

204 se' (HR) that involves programmed cell death at the site of pathogen recognition.

205 Diagnostic tests performed in the field or at the site of patient care would benefit from using a c

206 The maximum (64)CuCl2 uptake at the sites of PCa relapse was observed 1 h after trace

207 nable direct acquisition of neuronal signals at the site of peak stimulus strength minimally perturbe

208 The disruption of host-microbe homeostasis at the site of periodontal disease is considered a key f

209 taining the heavy hydrogen isotope deuterium at the site of peroxidation (D-PUFA) prevented PUFA oxid

210 doglycans (PGs) of diverse bacterial species at the sites of PG biosynthesis, allowing specific and c

211 Maternal and fetal cells intermingle at the site of placental attachment in the uterus, where

212 amyloid accumulated in the endometrium, only at the site of placental attachment, compromising matern

213 endothelial protein C receptor (EPCR) occurs at the sites of Plasmodium falciparum-infected erythrocy

214 s driven by CCL2 released from Schwann cells at the site of PNI, but not CCL7, an alternate ligand fo

215 ptor function to reestablish a receptor pool at the site of polarized growth.

216 sufficient accumulation of this key protein at the site of polarized growth.

217 osynthesis gene, creating a yellow highlight at the site of pollinator entry.

218 Signal quantification at the site of predominant lesion burden (thigh) reveale

219 nal sac onto the anterior wall of the uterus at the site of previous LSCS scar in a multipara female.

220 Relapse occurred at the site of primary disease in 10 patients, at a dist

221 lation and persistence of memory CD8 T cells at the site of primary infection.

222 Goals may include symptom relief at the site of primary tumor or from metastatic lesions.

223 We thus suggest that LFS transiently acts at the site of primordia initiation, where it provides a

224 and maintains mitochondria at the posterior at the site of primordial germ cell (PGC) formation thro

225 persistence of epidermal TRM preferentially at the site of prior infection despite sustained migrati

226 nergic effects" (GANE) model, high glutamate at the site of prioritized representations increases loc

227 Although the fibrinolytic system assembles at the site of pulmonary emboli, thrombus dissolution is

228 Furthermore, 3C cleaved PinX1 at the site of Q50-G51 pair through its protease activit

229 Focal nerve regeneration at the sites of radiofrequency ablation was observed in

230 in HeLa cells alters the methylation pattern at the site of recombination.

231 assembly of ESCRT III and accessory proteins at the site of repair.

232 n proteins capable of selective localization at the sites of rheumatoid arthritis (RA) are of particu

233 performance by raising the CO2 concentration at the site of ribulose-1,5-bisphosphate carboxylase/oxy

234 al epithelium on the denuded ovarian surface at the site of rupture when ovulation occurs, causing th

235 sis is caused by the activation of platelets at the site of ruptured atherosclerotic plaques.

236 The assay can be performed at the site of sample collection, with minimal user inte

237 ese LTP-like proteins form complexes and act at the site of SAR establishment.

238 data suggest that poly(ADP-ribose) synthesis at the sites of SBs initiates DNA damage signal transduc

239 isassembled along the apical plasma membrane at the site of secretory vesicle fusion and re-assembled

240 deficiency inhibited neutrophil accumulation at the site of sensitization.

241 y generating a greater inflammatory response at the site of simulated injection.

242 Macrophages recruited at the site of sterile muscle damage play an essential r

243 Newly synthesized Halo-actin was enriched at the site of stimulation, required NMDA receptor activ

244 rms of the ages of crust that are juxtaposed at the site of subduction initiation, they can be tested

245 rograms (>/=35% of tachycardia cycle length) at the site of successful ablation and were classified a

246 ontaining SUMO-remnant diglycyl-lysine (KGG) at the site of SUMO modification.

247 t that complement factor D (FD) is activated at the site of synthesis, and only FD lacking a propepti

248 etecting approximately 35-40 x 10(3) T cells at the site of T cell injection in the animal model.

249 rk allows coordinated phosphatase activities at the site of T-cell receptor activation, which is impo

250 vascular endothelial (VE)-cadherin staining at the site of TEM and targeted trafficking of the later

251 functional responses preferentially occurred at the sites of TESI versus non-TESI sites.

252 he localized partial outer retinal thickness at the site of test stimuli was determined as the distan

253 By multivariate analysis perfusion at the site of the anastomosis was the only significant

254 e proliferation and clonal expansion in vivo at the site of the aneurysmal lesion, in response to uni

255 ic model claiming a local activation process at the site of the angioedema attack.

256 of a local activation process of this system at the site of the attack is believed to lead to the for

257 FDG-PET revealed high inflammation levels at the site of the catheter after infection.

258 de evidence that this factor remains present at the site of the first lesion for several days and is

259 abeled subplate cells in the lateral pallium at the site of the future insular cortex.

260 At the site of the Grotte du Renne, Arcy-sur-Cure, morph

261 ed a localized sterile inflammatory reaction at the site of the injection, which resolved without com

262 We predict the geoneutrino flux at the site of the Jinping Neutrino Experiment (Sichuan,

263 he prevalence of perforating scleral vessels at the site of the lacquer crack, the position of the la

264 r vessels were found to perforate the sclera at the site of the lacquer crack.

265 myosin-regulatory light chain and localized at the site of the midbody formation in dividing wild-ty

266 k formation in Dictyostelia always initiates at the site of the morphogenetic organizer.

267 At the site of the nick there is a covalent linkage of T

268 by promoting insertion of near-cognate tRNAs at the site of the nonsense codon without apparent effec

269 es incorporated into the nascent polypeptide at the site of the PTC.

270 elevation of the retinal pigment epithelium at the site of the quiescent CNV visualized by structura

271 spectrometry detection are locally deposited at the site of the target through enzymatically catalyze

272 e of the two true local recurrences occurred at the site of the vessel.

273 Cleavage at the sites of the lesions was also observed but not fu

274 associated with APOBEC deregulation, is seen at the sites of the MYC translocation.

275 bone lesions, tendon and ligament pathology at the site of their insertion (enthesopathies).

276 sue sarcoma (STS) report a history of injury at the site of their tumor.

277 measures total drug and target concentration at the site of therapeutic action, as well as the amount

278 uced leukocyte recruitment and NET formation at the site of thrombosis.

279 is notably associated with hypersensitivity at the site of tissue injury.

280 elationship between the degree of metabolism at the site of tissue-sampling aspiration in lung lesion

281 TALAM1 RNA preferentially localizes at the site of transcription, and also interacts with MA

282 nal domain (CTD) that regulates interactions at the site of transcription.

283 ss-responsive transcriptional activator Atf1 at the sites of transcription, leading to activation of

284 tricular zone of neonatal cats and implanted at the site of transection in the medial longitudinal fa

285 and whether the pancreatic duct was dilated at the site of transection.

286 its associated catenins out of the junction at the site of transendothelial migration.

287 oly(ADP-ribose) synthesis catalysed by PARP1 at the sites of unrepaired SBs activates ARF transcripti

288 influenced by the presence of competing ions at the site of uptake.

289 Consistently, NONO is present at the sites of UV-induced DNA damage where it localizes

290 tters and a neuropeptide known to be present at the sites of valop expression.

291 thrombotic occlusion and intimal hyperplasia at the site of vascular anastomosis.

292 Platelet aggregation at the site of vascular injury is essential in clotting.

293 As platelets aggregate and activate at the site of vascular injury to stem bleeding, they ar

294 ired for fibrin formation and clot stability at the site of vascular injury.

295 the endothelial surface, in circulation, and at the sites of vascular injury.

296 At the site of vessel injury, pFn was rapidly deposited

297 hrombosis by enhancing platelet accumulation at the site of vessel injury.

298 resulted in about a twofold increase in AXR at the site of virus injection.

299 in dental calculus of Mesolithic human teeth at the site of Vlasac in the Danube Gorges of the centra

300 ncouples nascent IMVs from the IEV membranes at the site of wrapping.