ライフサイエンスコーパス: at the time of

1 red for 22 healthy male Wistar rats starting at the time of (18)F-FESCH (n = 12) and (18)F-FPSCH (n =

2 mL (mean, 6.2 ng/mL; range, 0.24-31.3 ng/mL) at the time of (18)F-fluciclovine and (68)Ga-PSMA-11 PET

3 The median PSA level at the time of (68)Ga-PSMA-11 PET/CT was 0.48 ng/mL (ran

4 peration, and she resided in a trial village at the time of a baseline survey before randomisation or

5 o be limited to women who were premenopausal at the time of a case [HR=1.07 (95% CI: 1.01, 1.14) base

6 y survey data representative of the province at the time of a child's birth.

7 use for DCIS had increased use of mastectomy at the time of a second breast event even among patients

8 l heart rhythm, low ejection fraction, shock at the time of admission, and ischemic time >25 minutes)

9 f pregnant women with primary HCMV infection at the time of amniocentesis may have a prognostic value

10 The CIS included point-of-care CD4+ testing at the time of an HIV-positive test, accelerated antiret

11 tients in the N3I3 arm (n = 6) were censored at the time of analysis as a result of dose-limiting tox

12 At the time of analysis, 109 patients (64%) experienced

13 At the time of analysis, 508 deaths were recorded (248 i

14 At the time of analysis, the median follow-up was 14 mon

15 At the time of analysis, the median follow-up was 84 mon

16 l rhabdomyosarcoma), all patients were alive at the time of analysis.

17 ssociated with coronary artery disease to 95 at the time of analysis.

18 unless exogenous calcium/magnesium was added at the time of anti-IgE stimulation.

19 ne and 3 multivisceral transplant recipients at the time of any operative resection, such as stoma cl

20 amoebic appendicitis, including 2 diagnosed at the time of appendectomy and 1 case diagnosed by rere

21 that HIV patients with high CD4+ cell counts at the time of ART initiation may be at greater risk of

22 Vmax >/=5 m/s at the time of AS diagnosis identifies patients with ver

23 We assessed the effect of CHIP at the time of ASCT on subsequent outcomes, including TM

24 ll transplantation (ASCT) for lymphoma, CHIP at the time of ASCT would be associated with an increase

25 When comparing cases at the time of assault to controls matched at the same t

26 ve an established diagnosis of schizophrenia at the time of assessment.

27 rometry (LC-MS) data, with lung cancer cases at the time of BAL collection.

28 rculating anti-HLA donor-specific antibodies at the time of biopsy, together with systematic gene exp

29 es including disease activity were evaluated at the time of blood collection.

30 f CSU, presence of angioedema, activity (UAS at the time of blood sampling and for 7 days), quality o

31 Vascular invasion was apparent at the time of bone formation but not earlier.

32 At the time of brain imaging, 1.5 years after initial ph

33 status, 25-hydroxyvitamin D (25OHD) measured at the time of breast cancer diagnosis, to determine the

34 have been driven by the observer's behaviour at the time of caching.

35 ents with breast cancer and brain metastases at the time of cancer diagnosis.

36 Patients who had an invasive airway in place at the time of cardiac arrest were excluded.

37 These results suggest that clinical AKI at the time of cardiac surgery is indicative of concurre

38 = 4) showed decreased activity prior to and at the time of cerebral diagnosis over a period of 13 to

39 with high sCD27 levels (median, >31.4 U/mL) at the time of CIS had a 5.5 times higher annualized rel

40 Their median age at the time of cladribine therapy was 62 years (age rang

41 FOR A SCIENTIFIC COMMENTARY ON THIS ARTICLE: At the time of clinical diagnosis, patients with Parkins

42 hortly before diagnosis and declines rapidly at the time of clinical onset of disease.

43 s (ie, the level of bacteremia), in patients at the time of clinical presentation on IL-10 production

44 s categorized in 2004 according to gestation at the time of commencing the new ration and in 2006 as

45 Evidence grading algorithm that was in place at the time of commissioning.

46 at first control, after starting sorafenib, at the time of complete response, and at least 1 month a

47 tion and reflection of the immunologic state at the time of conversion.

48 t marker correlated with the presence of CAV at the time of coronary angiography by using multivariat

49 nasal mucosal samples and decreased in blood at the time of COX-1 inhibitor reactions in 12 patients

50 ever-press reversal training, VMS inhibition at the time of cue presentation temporarily ceased and o

51 We found that VLS D2-MSNs were activated at the time of cue presentation.

52 At the time of CVD death, Mexicans (age, 67 [18] years)

53 At the time of CVH repair, intraperitoneal placement of

54 Subjects were followed from 33 to 84 months at the time of data analysis.

55 At the time of data cutoff, 104 patients (22%; 54 azithr

56 At the time of data cutoff, 447 patients (88%) had exper

57 At the time of data cutoff, the study was ongoing, with

58 e found that differences in bacterial burden at the time of death did not explain the two outcomes of

59 soidal obstruction syndrome that was ongoing at the time of death due to septic shock.

60 was additionally recruited for sampling once at the time of delivery.

61 risk assessment for pregnant women with CHD at the time of delivery.

62 s I or IIa guideline recommendations for CRT at the time of device implantation were included in this

63 tional cohort of patients eligible for CRT-D at the time of device implantation, nearly 90% received

64 506 eligible patients (88.6%) received CRT-D at the time of device implantation.

65 logic and clinical characteristics available at the time of diabetes diagnosis.

66 rogeria should have an ophthalmic evaluation at the time of diagnosis and at least yearly after that.

67 idence to inform best clinical practice both at the time of diagnosis and during follow-up.

68 Cysts were characterized at the time of diagnosis and during the follow-up period

69 e prognostic potential of microRNAs (miRNAs) at the time of diagnosis in MF.

70 A higher rate of undetected metastases at the time of diagnosis in younger women has been propo

71 dentified 968 patients with brain metastases at the time of diagnosis of breast cancer, representing

72 ar to be similar between adults and children at the time of diagnosis of celiac disease.

73 n be directly responsible for organ failures at the time of diagnosis or relapse.

74 ents with breast cancer and brain metastases at the time of diagnosis were identified using the Surve

75 a, comprising 7553 women aged 20 to 45 years at the time of diagnosis with invasive breast cancer, fr

76 The CIS included point-of-care CD4 testing at the time of diagnosis, accelerated ART initiation, an

77 , advanced stage and bilateral manifestation at the time of diagnosis, and aggressive course.

78 At the time of diagnosis, prediction of success of the i

79 redict disease progression of early-stage MF at the time of diagnosis.

80 be associated with low body mass index (BMI) at the time of diagnosis.

81 val in pulmonary arterial hypertension (PAH) at the time of diagnosis.

82 in quintiles was assigned based on residence at the time of diagnosis.

83 uded showed signs suggestive of inflammation at the time of diagnosis.

84 given that patients already present symptoms at the time of diagnosis.

85 or the presence of hypertension or hematuria at the time of diagnosis.

86 urance coverage through a spouse/parent plan at the time of diagnosis; 14% experienced a subsequent n

87 /L at the start of therapy or <100 x 10(9)/L at the time of discontinuation were associated with shor

88 herapy could cross over to receive nivolumab at the time of disease progression.

89 patients were analyzed for C1q-binding dnDSA at the time of dnDSA detection, and 1-year later or at t

90 ion and 16 (36%) had impaired graft function at the time of dnDSA detection.

91 ed pneumonia (CAP) and children asymptomatic at the time of elective outpatient surgery (controls) we

92 nterval (CI): 1.28, 3.68) and being a smoker at the time of enlistment (HR = 1.91, 95% CI: 1.32, 2.76

93 9 (60.2%) had undergone intracranial imaging at the time of enrollment (mean [SD] age at enrollment,

94 and predefined risk variables were collected at the time of enrollment to enable prognostic model dev

95 The PSA level could be rising or falling at the time of enrollment, but had to be higher than 4.0

96 12 months; 96% were receiving statin therapy at the time of enrollment.

97 differs from early-born DGCs that are mature at the time of epileptogenesis.

98 Users currently taking AAS at the time of evaluation (N=58) showed significantly re

99 95%) not diagnosed with a psychotic disorder at the time of examination were hospitalized for nonaffe

100 a prognostic score for predicting mortality at the time of extracorporeal membrane oxygenation initi

101 ne of whom underwent noninvasive ventilation at the time of extracorporeal membrane oxygenation initi

102 atory muscle strength (aPiMax </= 30 cm H2O) at the time of extubation, and were nearly three times m

103 any novel therapeutic characteristics known at the time of FDA approval were associated with increas

104 Novel therapeutic characteristics known at the time of FDA approval, including drug class, thera

105 clinically applicable prognostic assay that at the time of first relapse identifies patients with un

106 34.2%]; 805 white [99.9%]) with a median age at the time of first staged excision procedure of 65 yea

107 lost more than 2 Snellen lines from baseline at the time of fluid accumulation.

108 Patients younger than 18 years at the time of FMD diagnosis were excluded.

109 the baseline study correlated with the LVEF at the time of follow-up (r=0.33; P<0.001).

110 umed source of bacteremia, antibiotic status at the time of FUBC, antibiotic susceptibility, presence

111 istology, intermediate- or poor-risk disease at the time of GCT diagnosis, and human chorionic gonado

112 3% were male, and 81.3% had stage IV disease at the time of genomic analysis, with prostate, renal, p

113 lity can be identified based on mental state at the time of high SI and identified four potential sub

114 scoring system that stratifies burn patients at the time of hospital admission according to risk of d

115 ignificant emphasis on improving transitions at the time of hospital discharge for patients with HF.

116 e collection of biosamples and clinical data at the time of ICU admission and again 3 days later.

117 If patients had capacity at the time of ICU admission, or if a surrogate was read

118 Host response reactions were similar at the time of ICU-acquired infectious or noninfectious

119 At the time of imaging, behavioural evaluation with the

120 lly eligible and willing to donate each year at the time of imminent death.

121 sults suggest that the quality of pTfh cells at the time of immunization is important for influenza v

122 Group A was significantly older at the time of implantation and achieved higher graft fu

123 brane, and thus, they can be cut or reshaped at the time of implantation for applications in small or

124 des alternating with periods of sinus rhythm at the time of implantation had a better survival than t

125 The mean age was 75 years at the time of implantation; 25.3% were <70 years of age

126 We identified 905 patients that were married at the time of incident HF diagnosis in Olmsted County,

127 eme for diagnostic communication, especially at the time of index diagnosis, and in scientific studie

128 The majority were symptomatic at the time of index echocardiogram (New York Heart Asso

129 data and endoscopic and histologic findings at the time of index endoscopy.

130 Initial management strategy at the time of index hospitalization, including nonproce

131 n RNA improves heart function when delivered at the time of infarct or after ischaemic heart failure

132 ose of 150 mg/kg given twice a day initiated at the time of infection can reduce the peak median VL b

133 treatment is given prophylactically starting at the time of infection.

134 ting for airflow limitation in the community at the time of initial diagnosis (43.8% vs 55.6%, respec

135 nds screening of youths with type 2 diabetes at the time of initial diagnosis.

136 nistic hypotheses in two sets of experiments at the time of initial diagnosis.

137 tein insertion and translocation machineries at the time of initial membrane insertion and folding.

138 ith morphologic findings from index biopsies at the time of initial PVN diagnosis.

139 risk factors, and other biomarkers measured at the time of initial VTE with recurrent VTE in a presp

140 At the time of initiating the procurement process, deman

141 r aggravation of bleeding; anticoagulant use at the time of injury can also contribute to bleeding ri

142 c and injury covariates, depression symptoms at the time of injury predicted (p</=0.05) both poorer w

143 At the time of intravitreal aflibercept injection initia

144 bfield thickness from baseline in these eyes at the time of intravitreal aflibercept injection initia

145 estimated that the effective population size at the time of introduction was actually small (less tha

146 med after 2005, a longer duration of disease at the time of IRA, indication for colectomy and having

147 f deep vein thrombosis or pulmonary embolism at the time of IVC filter placement.

148 tor AG490 given systemically or into the OFC at the time of ketamine injection prevented its benefici

149 At the time of kidney transplant, we obtained and analyz

150 partial PPVs or anterior vitrectomies (AVs) at the time of KPro implantation (n = 26).

151 emale; 33 (73%) were white; and the mean age at the time of laser treatment was 14.5 years (range, 0-

152 Foliar residues measured at the time of leaf fall were used as input parameters f

153 outcomes in young adults ages 18 to 24 years at the time of listing and transplantation compared to o

154 analysis identified recipients with diabetes at the time of listing as the strongest predictor of pos

155 ited Network for Organ Sharing (UNOS) status at the time of listing.

156 At the time of LT, 39% of recipients had PH (mPAP >/= 25

157 An intact t-system at the time of LVAD implantation may constitute a precon

158 Low ryanodine receptor-sarcolemma distances at the time of LVAD implantation predicted high post-LVA

159 in patients with acceptable quality of life at the time of LVAD implantation.

160 procedures other than tricuspid valve repair at the time of LVAD.

161 ere premenopausal, and 6,481 postmenopausal, at the time of mammography.

162 ic Surgeon A advised placement of an implant at the time of mastectomy while Surgeon B contrasted the

163 patients who do not have acute kidney injury at the time of measurement.

164 Its RNA is up-regulated 23-fold at the time of meso-zeaxanthin production during chicken

165 ne analog-containing minipumps were inserted at the time of MI induction.

166 orrelated with fetal liver and brain volumes at the time of MRI as well as with birth weights.

167 Blocking the IFN-I receptor at the time of Nb treatment had little effect on DC migr

168 ts with folate-sensitive metabolic processes at the time of neural tube closure.

169 Five patients had acute cellular rejections at the time of non-HLAabs development, 4 had viral infec

170 ) and 16 (95% UR: 9-23) per 100,000 per year at the time of novel regimen introduction and RR TB inci

171 ession and neuronal maturation and decreases at the time of OR stabilization; (2) colocalizes with th

172 und loci associated with resting heart rate, at the time of our study these loci explained 0.9% of th

173 atients with isolated thoracic cord myelitis at the time of pain onset were significantly more disabl

174 ctrocatalytic oxidation of hydrazine exactly at the time of Pd-NP collision to the CFUME surface, was

175 in the field of view should be below 3.3 GBq at the time of PET imaging to avoid deadtime losses for

176 Patterns of inflammation at the time of PML diagnosis and at the PML-IRIS stage o

177 ty criteria (based on age at immigration and at the time of policy implementation) before and after p

178 lmonary hemodynamic variables were collected at the time of PoPH diagnosis, at last evaluation before

179 Empiric antimycotic prophylaxis initiated at the time of positive culture result reduced the incid

180 and performed systematic allograft biopsies at the time of post-transplant serum evaluation.

181 the development of microvascular obstruction at the time of PPCI may identify high-risk patients who

182 no patients had previously taken alendronate at the time of prednisolone initiation.

183 Subanalysis was performed by symptom status at the time of presentation.

184 JC polyomavirus was detected in the CSF at the time of presentation.

185 ed 6612 (16%) to be eligible for MMR vaccine at the time of pretravel consultation.

186 of revision surgery based on increasing age at the time of primary surgery.

187 Biopsy findings at the time of procurement of deceased donor kidneys rem

188 lterations are present in seventeen subjects at the time of progression.

189 This could be used to select men for entry at the time of PSA nadir onto randomized trials evaluati

190 5 and 1.0 ng/mL, considered eligible for SRT at the time of PSMA.

191 LCI (n = 26) or MRI (n = 10) were performed at the time of pulmonary exacerbation and after antibiot

192 At the time of randomization to active surveillance, a s

193 t population (3 had overt distant metastases at the time of randomization; 2 withdrew consent).

194 c antifungal therapy was started empirically at the time of rash presentation and continued for a med

195 ase received eculizumab: 10 from day 0 and 2 at the time of recurrence (days 6 and 25).

196 At the time of registry enrollment, GenTAC study partici

197 Although a dFLC of >5 mg/dL at the time of reinstituting therapy was associated with

198 imens demonstrated that the biology captured at the time of relapse contained superior properties for

199 ven of these pancreatectomies were performed at the time of repeat transplant and were analyzed separ

200 At the time of reperfusion, indocyanine green-based in v

201 appears to have decreased nodal involvement at the time of resection and increased survival compared

202 At the time of restarting therapy, median difference of

203 Our observations and analyses indicate that, at the time of sample collection, Microcystis population

204 umber of people present in a sewer catchment at the time of sample collection.

205 Mean (SD) age at the time of sampling was 51 (16) years, 161 patients

206 dy was based on a long-term experiment (7 yr at the time of sampling) in which a C4 pasture grass (Pa

207 a standard aortic cannula (control; n = 132) at the time of SAVR.

208 D) age of 119 patients was 9.65 (1.31) years at the time of scan.

209 uration of illness (after accounting for age at the time of scanning) was associated with reduced cor

210 sychosis but no associations with mood state at the time of scanning.

211 , and requirement for systemic immunotherapy at the time of screening.

212 Prompt systemic antifungal treatment at the time of skin presentation for >/=14 days prevents

213 de the possibility of disordered coagulation at the time of stroke but suggests testing in childhood

214 herapeutic warfarin anticoagulation (INR <2) at the time of stroke, 37674 (39.9%) were receiving anti

215 Best practice for active surveillance at the time of study design was followed (ie, biopsy at

216 symptoms at the time of the OSRC, as well as at the time of study enrollment, 1-3 y after the spill.

217 of the remaining 1495 patients was 53 years at the time of study entry; 157 (11%) had axillary node-

218 d as new and/or progressive brain metastases at the time of study entry; and those with leptomeningea

219 nin-T, and growth-differentiation factor 15) at the time of study inclusion.

220 % CI, 0.75-0.8]; P=0.008] pulmonary arteries at the time of subsequent surgical repair or last follow

221 netic resonance imaging (MRI) were performed at the time of suggestive symptoms and during routine fo

222 cation of prostate cancer in frozen sections at the time of surgery can be challenging, limiting the

223 Diagnosis was made predominantly (78.9%) at the time of surgery or on pathology; 31.8% (2168) rec

224 The mean age at the time of surgery was 76.4 years.

225 d to have higher levels of plasma fibrinogen at the time of surgery, with unchanged prothrombin time.

226 fibroids, who were not on hormonal treatment at the time of surgery.

227 ars at the study start and 41.7 (10.0) years at the time of surgery.

228 of fellow eyes, despite having a shorter AL at the time of surgery.

229 ars at the study start and 41.0 (10.0) years at the time of surgery.

230 consistently observed in obstructing tissue at the time of surgical correction, suggest that Hedgeho

231 ly higher risks of various negative outcomes at the time of survey: bitterness toward health care pro

232 ng inducible VT/VF without ECG documentation at the time of symptoms.

233 tal of 604 patients undergoing CAD screening at the time of TAVR procedure were prospectively include

234 were born 10 years apart, with the same age at the time of the assessment in the 1998 and 2008 surve

235 on, higher urinary angiogenin concentrations at the time of the biopsy associated with worse renal fu

236 ) or placebo (n = 237) for 2 years, starting at the time of the conditioning regimen.

237 Results At the time of the data snapshot, median follow-up was 1

238 We present the final analysis, although at the time of the database lock, 15 patients were still

239 ng that ascends beneath the Reunion hot spot at the time of the Deccan eruptions.

240 If incident cases at the time of the first CT examination were not exclude

241 und that adjustment for the confounder value at the time of the first questionnaire after the start o

242 At the time of the first vertebrate-specific whole genom

243 Among three people dead at the time of the follow-up survey, one was deemed to b

244 the absence of relevant clinical information at the time of the imaging study.

245 based on clinical variables that are present at the time of the initial evaluation after OGI.

246 At the time of the interim analysis, 745 (99%) of the pl

247 At the time of the interim analysis, the median follow-u

248 ion to the total Yazidi population of Sinjar at the time of the ISIS attack are the main limitations

249 the total Yazidi population living in Sinjar at the time of the ISIS attack, estimated at roughly 400

250 s associated with a range of health symptoms at the time of the OSRC, as well as at the time of study

251 ging and prognostic estimates are determined at the time of the patient's initial disease presentatio

252 ertebral and symptomatic vertebral fracture) at the time of the primary analysis (after clinical frac

253 incidences of nonvertebral and hip fracture at the time of the primary analysis.

254 continued HA use and 14 discontinued HA use at the time of the questionnaire.

255 type and marker levels measured at baseline, at the time of the repeated sample, and with the rate of

256 Results The mean age at the time of the study was 16.3 +/- 4.7 years; the mea

257 atment; lowest in those taking the treatment at the time of the study, higher in those who never took

258 e being treated with inhaled corticosteroids at the time of the study.

259 ddPCR based DNA quantification measurements at the time of the study.

260 l patients were free of any active infection at the time of the study.

261 ay of the survey and who were not discharged at the time of the survey were included.

262 postdeployment symptoms reported as present at the time of the survey were largely independent of de

263 those reported kidnapped were still missing at the time of the survey.

264 All participants were 18 years or older at the time of the survey.

265 The mean (SD) age was 61.8 (12) years at the time of the survey.

266 households contained 6,572 living residents at the time of the survey; 43 killings and 83 kidnapping

267 were alive and enrolled in a treatment trial at the time of the visit).

268 Each patient was included once, at the time of their first colistin-tested CRKp positive

269 aucoma) according to the severity of disease at the time of their first examination by an ophthalmolo

270 n of all ages; 5 (19%) were <6 months of age at the time of their first illness.

271 iphtheria and tetanus toxoids and aP vaccine at the time of their first pertussis infection, 1 (4%) h

272 All variants were novel at the time of their identification.

273 ients with therapy-related myeloid neoplasms at the time of their primary cancer diagnosis and before

274 and 106 in the control group) were recruited at the time of their work-up for breast cancer; they com

275 e impairment after WBRT should be considered at the time of therapeutic decision.

276 At the time of this analysis, 65 (76%) TBP patients and

277 'genome-wide significance' (P < 5 x 10(-8)) at the time of this analysis, but a much larger number o

278 6 [84%] of patients are continuing ibrutinib at the time of this report.

279 rmal knee joints and from OA-affected joints at the time of total knee arthroplasty.

280 cification and commitment coincide and occur at the time of transcriptional stabilization, whereas IC

281 cipients and given a single dose of CTLA4-Fc at the time of transplant and 4doses of anti-CD154 mAb t

282 nts who were Epstein-Barr virus-seronegative at the time of transplant and at risk of primary infecti

283 Patients were censored for death with LVAD at the time of transplant or the last day of the study.

284 During the end-stage renal disease phase at the time of transplant, cinacalcet, and native vitami

285 ng treatment for portopulmonary hypertension at the time of transplant.

286 patients undergoing ASCT for lymphoma, CHIP at the time of transplantation is associated with inferi

287 ence of donor-specific alloantibodies (DSAs) at the time of transplantation leads to acute and chroni

288 At the time of transplantation, 39 (72%) patients had de

289 ndothelial keratoplasty tissue vs other uses at the time of transplantation, likely owing in part to

290 routine laboratory data available before or at the time of transplantation.

291 ed that the better the visual acuity (VA) is at the time of treatment initiation, the higher the like

292 anticoagulant therapy on menstrual bleeding at the time of treatment initiation.

293 At the time of tuberculosis diagnosis, IDO activity was

294 ying driver mutations had a heavy right tail at the time of tumor detection, with only 1 to 4 dominan

295 Surprisingly, Ng2/Cspg4 deletion at the time of tumor initiation resulted in larger tumor

296 ion (pre-F) to the postfusion (post-F) state at the time of virus-host cell membrane fusion.

297 cates that the autoimmune program was active at the time of weaning.

298 blinded to the study group every 4 days and at the time of withdrawal from the study, due to cessati

299 decreased by >99.9%, compared with 1988, and at the time of writing, only 3 countries in which wild p

300 over 2 years rather than 1 year, and if done at the time of year when transmission is lowest.