ライフサイエンスコーパス: atrazine

1 uoranthene), and agrochemical (the herbicide atrazine).

2 n testosterone levels when exposed to 25 ppb atrazine.

3 desisopropylatrazine but is not active with atrazine.

4 (PhAIEI) for the detection of the herbicide atrazine.

5 extensively used pesticides, acetamiprid and atrazine.

6 y based biosensor to detect trace amounts of atrazine.

7 oil-mobility pesticides, one such example is atrazine.

8 Larvae were exposed to atrazine (0.01-200 ppb) by immersion throughout larval d

9 yield is near 0.5 (4-CBA: 0.56, 4-NBA: 0.49, atrazine: 0.6).

10 posed to two concentrations of the herbicide atrazine (100 and 250 mug L(-1)).

11 -ethylamino-6-isopropylamino-1,3,5-triazine (atrazine), 2.4-dichlorophenoxyacetic acid (2,4-D), 2,4,6

12 , 100, and 0.02 mug L(-1) were found for OA, atrazine, 2,4-D, TNT, and RDX, respectively.

13 ldehyde (177 --> 149 for protonated ion) and atrazine (221 --> 179) were found to be linear in the ra

14 st rate with atrazine (k (hydroxyl radical + atrazine) = 3 x 10(9) M(-1) s(-1)).

15 loroethane (72 years), paraoxon (13 months), atrazine (5 months), and aziridine (52 h).

16 radicals degrade a significant proportion of atrazine (63%) via dealkylation, in which deethylation s

17 The herbicide atrazine, a suspected endocrine disrupting chemical (EDC

18 Atrazine, acetochlor, metolachlor, and trifluralin were

19 mplexation and positive current change after atrazine addition in solution.

20 Previous studies showed that atrazine adversely affects amphibian larval development.

21 For example, the herbicide atrazine affects host defences (e.g. resistance and tole

22 ironmental concentration (EEC; 200 mug/L) of atrazine affects the gut bacterial composition of Cuban

23 3)C/(12)C) isotope plots for dealkylation of atrazine agree with indirect photodegradation but differ

24 these often debilitating larval trematodes (atrazine alone accounted for 51%).

25 In the analysis of atrazine alone, samples could be injected every 4 min an

26 s-Triazine herbicides (atrazine, ametryn) are groundwater contaminants which ma

27 The detection limit of the assays for atrazine and 2,3,7,8-tetrachlorodibenzo-p-dioxin was 2.0

28 The herbicides, atrazine and alachlor, but not 2,4-D, were associated wi

29 he general validity of these conclusions for atrazine and ametryn with purified TrzN and a TrzN-E241Q

30 Cyanazine was 5 times more soluble than atrazine and an order of magnitude more soluble than sim

31 Mercapturate metabolites of atrazine and dealkylated atrazine dominated the early me

32 her supporting a causal relationship between atrazine and elevated trematode infections in amphibians

33 frequently contaminate hives-two herbicides (atrazine and glyphosate) and three fungicides (boscalid,

34 We were able to simultaneously measure atrazine and its major mammalian metabolites, which incl

35 Existing analytical methods to analyze atrazine and its metabolites in biological matrices have

36 ll be a useful tool for the determination of atrazine and its metabolites in future pharmacokinetic s

37 d sensitive LC-MS method for the analysis of atrazine and its metabolites in mouse urine and plasma.

38 n of industrial s-triazine compounds such as atrazine and melamine into the environment.

39 The present findings exemplify the role that atrazine and other endocrine-disrupting pesticides likel

40 ese results raise concerns about the role of atrazine and phosphate in amphibian declines, and illust

41 The combination of atrazine and phosphate--principal agrochemicals in globa

42 centration-dependent manner by the triazides atrazine and terbutryn, but not by nitrile or phenylurea

43 xamine the sorption affinity of bisphenol A, atrazine, and diuron to five soils of varying OM composi

44 inary metabolites of the triazine herbicide, atrazine, and the analytical performance of AMS has been

45 f low mass analytes like arginine, fructose, atrazine, anthracene and paclitaxel.

46 ater by using three coupled columns: an anti-atrazine antibody column for the selective extraction of

47 sents negative current change following anti-atrazine antibody complexation and positive current chan

48 ptide VPGVG and a single-chain Fv of an anti-atrazine antibody were synthesized biologically and puri

49 electrode and coupled with a monoclonal anti-atrazine antibody.

50 This study provides evidence to support atrazine as an EDC causing reproductive dysfunction and

51 yl atrazine, desisopropyl atrazine, desethyl atrazine, atrazine-glutathione conjugate, and atrazine-m

52 environmentally relevant detection limits of atrazine attained with the PhAIEIS may have direct appli

53 Atrazine (Atz) and its metabolite desethylatrazine (DEA)

54 The widely-used herbicide atrazine (ATZ) is detected in ground and surface water i

55 al effects promoted by widely used herbicide atrazine (ATZ).

56 l detection and degradation of the pesticide atrazine (Atz).

57 henoxybenozic acid, 4-nitrophenol, alachlor, atrazine, azoxystrobin, chlorpyrifos, diazinon, diuron,

58 erbicide test mixture (composed of alachlor, atrazine, butachlor, hexachlorocyclopentadiene, metolach

59 DP initiates the metabolism of the herbicide atrazine by catalyzing a hydrolytic dechlorination react

60 tiates bacterial metabolism of the herbicide atrazine by hydrolytic displacement of a chlorine substi

61 ure of a catabolic plasmid and show that the atrazine catabolic genes are dispersed on three disparat

62 In this study, the third gene in the atrazine catabolic pathway, atzC, was cloned from a Pseu

63 ndom events, have been reconstituted onto an atrazine catabolic plasmid.

64 r results indicate that globally distributed atrazine-catabolic genes are highly conserved in diverse

65 , atzD, atzE, and atzF, which participate in atrazine catabolism.

66 Atrazine chlorohydrolase (AtzA) from Pseudomonas sp. ADP

67 ine deaminase is 98% identical to the enzyme atrazine chlorohydrolase (AtzA) from Pseudomonas sp. str

68 chlorohydrolase, TrzN (triazine hydrolase or atrazine chlorohydrolase 2), initiates bacterial metabol

69 Atrazine chlorohydrolase, TrzN (triazine hydrolase or at

70 n names of the pesticides studied are 2,4-D, atrazine, chlorpyrifos, malathion, permethrin, and propo

71 , AMPA, chlorpyrifos, dieldrin, metolachlor, atrazine, CIAT, glyphosate) and two pharmaceuticals (caf

72 found in bacteria that grow on melamine and atrazine compounds, respectively.

73 92 and 104%) were demonstrated in simulated atrazine-contaminated water samples.

74 the solubilities of the triazine pesticides atrazine, cyanazine, and simazine were measured in pure

75 k = 2 x 10(9) M(-1) s(-1)), whereas desethyl-atrazine (DEA) reacts more slowly (k = 9.6 x 10(8) M(-1)

76 Our results indicate that AtzA is a novel atrazine-dechlorinating enzyme with fairly restricted su

77 ulfate radicals (e.g., desethyl-desisopropyl-atrazine (DEDIA; 1.5 x 10(8) M(-1) s(-1))).

78 nt species [para-chlorobenzoic acid (p-CBA), atrazine, DEET, and ibuprofen] was not significantly inh

79 ydrolysis of allophanate, an intermediate in atrazine degradation and urea catabolism pathways, to NH

80 AMF has important ecological significance on atrazine degradation but also provide evidence for the m

81 ide evidence for the molecular mechanisms of atrazine degradation by AMF.

82 viously, inverse nitrogen isotope effects in atrazine degradation by Arthrobacter aurescens TC1 (i) d

83 minohydrolase, AtzC, the third enzyme in the atrazine degradation pathway in Pseudomonas sp. strain A

84 It was observed that the atrazine degradation rates with any addition level in my

85 Glomus mosseae/Medicago sativa mycorrhiza on atrazine degradation was investigated.

86 e, we show that five geographically distinct atrazine-degrading bacteria contain genes homologous to

87 e identities of the atz genes from different atrazine-degrading bacteria were greater than 99% in all

88 ich include didealkyl atrazine, desisopropyl atrazine, desethyl atrazine, atrazine-glutathione conjug

89 mmalian metabolites, which include didealkyl atrazine, desisopropyl atrazine, desethyl atrazine, atra

90 d on a competitive enzymatic immunoassay for atrazine detection was used to test the performance of t

91 For example, desisopropyl-atrazine (DIA) reacts quickly (k = 2 x 10(9) M(-1) s(-1)

92 dances of two bacterial genera in adulthood, atrazine did not affect gut bacterial diversity or commu

93 d refinement of biologically based models of atrazine disposition.

94 sampler (n = 258) derived concentrations of atrazine, diuron, ametryn, and metolachlor by an average

95 and coastal waters, our EDA study shows that atrazine, diuron, irgarol, isoproturon, terbutryn, and t

96 ms and kinetics of four representative HOCs (atrazine, diuron, naphthalene, and biphenyl) onto Mag-PC

97 diated by host-associated microbiota because atrazine does not affect microbiota of tadpoles or adult

98 rate metabolites of atrazine and dealkylated atrazine dominated the early metabolic time points, acco

99 ral exposures of a limited number of mice to atrazine (doses, 5-250 mg/kg body weight) to demonstrate

100 substrate that was structurally identical to atrazine, except for the substitution of an amino group

101 Atrazine-exposed males suffered from depressed testoster

102 Atrazine-exposed males were both demasculinized (chemica

103 emonstrates the reproductive consequences of atrazine exposure in adult amphibians.

104 l to developing useful assays for monitoring atrazine exposure in agricultural workers.

105 Embryonic atrazine exposure resulted in a significant increase in

106 ber of toxicological effects associated with atrazine exposure with the concentrations of this compou

107 n in ecosystem functioning (productivity) by atrazine for both traits.

108 samples collected over a 1 month period were atrazine, fuberidazole, imidacloprid, terbumeton, and cl

109 e, desisopropyl atrazine, desethyl atrazine, atrazine-glutathione conjugate, and atrazine-mercapturat

110 ACR that cochromatographed with a synthetic atrazine-glutathione conjugate.

111 ngle and combined effects of two herbicides (atrazine, glyphosate), and three insecticides (malathion

112 s of activities with a variety of chemicals (atrazine, glyphosate, organophosphates, 4-[2,4-dichlorop

113 Atrazine (> or =0.1 ppb) induced hermaphroditism and dem

114 Atrazine had a significant dose-response trend with part

115 n of LSPR immunosensors for the detection of atrazine herbicide.

116 tive immunoassay based on the competition of atrazine-horseradish peroxidase and atrazine was establi

117 gest that other amphibian species exposed to atrazine in the wild could be at risk of impaired sexual

118 y of cytochrome P450-catalyzed metabolism of atrazine in vitro.

119 both transformations, (13)C/(12)C ratios of atrazine increased strongly (epsilon(carbon/permanganate

120 ionalis) tadpoles and adults and whether any atrazine-induced change in community composition might a

121 We hypothesize that atrazine induces aromatase and promotes the conversion o

122 Atrazine is a herbicide widely used on agricultural comm

123 Atrazine is also a potent endocrine disruptor that is ac

124 Thus, in the presence of humic acids, atrazine is degraded more efficiently by sulfate radical

125 At 100 degrees C, the solubility of atrazine is doubled when the water is modified with urea

126 The herbicide atrazine is one of the most commonly applied pesticides

127 e to grow under high light conditions unless atrazine is present to inhibit PS II activity.

128 e data obtained from this study suggest that atrazine is rapidly metabolized in mice.

129 for sensitive and selective determination of atrazine is reported.

130 As a result, atrazine is the most commonly detected pesticide contami

131 Atrazine is the most commonly used herbicide in the U.S.

132 radicals react at an equally fast rate with atrazine (k (hydroxyl radical + atrazine) = 3 x 10(9) M(

133 pesticides such as fenamiphos, isoproturon, atrazine, linuron, thiamethoxam, trifluralin, carbaryl,

134 ng the urinary metabolites of the pesticides atrazine, malathion, and 2,4-dichlorophenoxyacetic acid

135 respectively, calculated on the basis of the atrazine marker.

136 Trends in multielement isotope data of atrazine may, therefore, decipher different degradation

137 trazine, atrazine-glutathione conjugate, and atrazine-mercapturate, using preparation procedures that

138 The excreted atrazine metabolites became more polar with increasing t

139 and separated the parent compound and major atrazine metabolites over 31 min on an octadecylsilane c

140 Atrazine, metolachlor, trifluralin, and pendimethalin we

141 s the immunocomplex of atrazine with an anti-atrazine monoclonal antibody.

142 Atrazine monotonically (i.e., consistently increasing or

143 se-response trend with participants applying atrazine more than 20 days/year having an OR of 1.5 (95%

144 These data are consistent with effects of atrazine observed in other vertebrate classes.

145 alkylated metabolites and thio conjugates of atrazine observed.

146 ain sorption-retarded breakthrough times for atrazine of 54 or 5.8 years, respectively, at a 1 in./h

147 Our results suggest that the effect of atrazine on Bd infection risk is not mediated by host-as

148 We examined the effects of atrazine on sexual development in African clawed frogs (

149 e-quarters of FSE maize fields, growers used atrazine on the conventionally managed half, reflecting

150 RA were observed for lifetime days of use of atrazine [ORtertile3= 1.62 (95% CI: 1.09, 2.40); ptrend=

151 ects were given a dermal dose of 14C-labeled atrazine over 24 h, and urine from the subjects was coll

152 cid (4-CBA), 4-nitrobenzoic acid (4-NBA) and atrazine present in trace amounts (1 muM) has been follo

153 compost DOC than straw DOC (particularly for atrazine, prometon, benzotriazole, and fipronil).

154 Atrazine, propazine, and terbuthylazine are chlorotriazi

155 Atrazine residues were used to differentiate between neo

156 Additionally, the basis for atrazine resistance was investigated in MCR and an atraz

157 tion mechanisms contribute to mesotrione and atrazine resistance within the MCR population.

158 Sequence analysis of atrazine-resistant (MCR and ACR) and atrazine-sensitive

159 ne resistance was investigated in MCR and an atrazine-resistant but mesotrione-sensitive population (

160 CR for Adams County mesotrione-sensitive but atrazine-resistant).

161 nated MCR (for McLean County mesotrione- and atrazine-resistant).

162 ons of 208nM and 2.1microM for terbutryn and atrazine, respectively, with limits of detection estimat

163 y of 0.03 and 1.3mug/L for sulfasalazine and atrazine, respectively.

164 lected triazine herbicides namely, simazine, atrazine, secbumeton and cyanazine were employed to esti

165 ysis of atrazine-resistant (MCR and ACR) and atrazine-sensitive (WCS) waterhemp populations detected

166 Withdrawal of the triazine herbicides atrazine, simazine and cyanazine from approved lists of

167 Atrazine, simazine, and cyanazine were used as model ana

168 AtzA catalyzes the dechlorination of atrazine, simazine, and desethylatrazine but is not acti

169 leveraging the size based immobilization of atrazine small molecules we have designed electrochemica

170 the identification of genes corresponding to atrazine stress in the AM association.

171 sed genes in AM association with and without atrazine stress were associated with molecular processes

172 emonstrated that, relative to control tanks, atrazine tanks had immunosuppressed tadpoles, had signif

173 on four photosystem II inhibitor herbicides (atrazine, terbutryn, diuron, and isoproturon) and 14 dia

174 l and monoclonal) specific for the herbicide atrazine, the antibiotic sulfasalazine, and the vitamin

175 ice that can identify trace contamination of atrazine through a label-free assay.

176 to 0, 0.3, 3, or 30 parts per billion (ppb) atrazine through embryogenesis and then allowed to matur

177 Pseudomonas sp. strain ADP metabolizes atrazine to carbon dioxide and ammonia via the intermedi

178 Pseudomonas sp. strain ADP metabolizes atrazine to cyanuric acid via three plasmid-encoded enzy

179 The times for 50% of absorbed atrazine to degrade in corn, MCR, and ACR leaves were sh

180 d contributes to the microbial hydrolysis of atrazine to hydroxyatrazine in soils and groundwater.

181 rame, atzA, encoded an activity transforming atrazine to hydroxyatrazine.

182 riazine ring substituents from the herbicide atrazine to yield cyanuric acid.

183 carbon=-5.0 per thousand+/-0.2 per thousand (atrazine/TrzN), epsiloncarbon=-4.2 per thousand+/-0.5 pe

184 itrogen=2.5 per thousand+/-0.1 per thousand (atrazine/TrzN), epsilonnitrogen=2.1 per thousand+/-0.3 p

185 carbon=-4.2 per thousand+/-0.5 per thousand (atrazine/TrzN-E241Q), epsiloncarbon=-2.4 per thousand+/-

186 itrogen=2.1 per thousand+/-0.3 per thousand (atrazine/TrzN-E241Q), epsilonnitrogen=3.6 per thousand+/

187 elevant concentrations of chlorothalonil and atrazine, two of the most commonly used, immunomodulator

188 ment to be considerably larger than that for atrazine used before weeds emerged, but still smaller th

189 domonas strain ADP metabolizes the herbicide atrazine via three enzymatic steps, encoded by the genes

190 The solubility of atrazine was also measured in ambient and hot water modi

191 When atrazine was applied at 20 mg kg(-1), the removal effici

192 eatly relative to all other regimes whenever atrazine was applied before weeds emerged.

193 Ring-labeled [14C]atrazine was applied for 24 h with a dermal patch to hum

194 orter than in WCS, and a polar metabolite of atrazine was detected in corn, MCR, and ACR that cochrom

195 ition of atrazine-horseradish peroxidase and atrazine was established with IC(50) and lower detection

196 Didealkyl atrazine was the most abundant metabolite detected in th

197 here we show that the widely used herbicide, atrazine, was the best predictor (out of more than 240 p

198 The effects of atrazine were consistent across trematode taxa.

199 Metabolites of atrazine were measured in human urine after dermal expos

200 y with atratone, and a 10-fold decrease with atrazine, when compared with wild-type TrzN.

201 nged from 90 to 100% except for simazine and atrazine which were 50% and 74%, respectively.

202 led a limit of detection (LOD) of 3.5 pM for atrazine, which, to the best of our knowledge, is one of

203 th a limit of detection (LoD) at 1pM, and of atrazine with a linear range of responses from 100pM to

204 specifically recognizes the immunocomplex of atrazine with an anti-atrazine monoclonal antibody.

205 croM in plasma following the highest dose of atrazine), with lesser quantities of mono N-dealkylated

206 , catalyzes the hydrolytic dechlorination of atrazine, yielding hydroxyatrazine.