ライフサイエンスコーパス: atrioventricular

1 block, sinus arrest, 2 degrees and 3 degrees atrioventricular (A-V) block and supraventricular escape

2 e at different increments of heart rate, and atrioventricular and interventricular delay.

3 repeated prolonged episodes of third-degree atrioventricular and sinoatrial block in every NaV1.5-im

4 The cardiac sodium channel SCN5A regulates atrioventricular and ventricular conduction.

5 mogenic foci can originate in areas near the atrioventricular annuli, we hypothesized that focal annu

6 novel tool and insights into ionic bases of atrioventricular AP differences, and shows how Na+ and C

7 the developing heart, including cells in the atrioventricular (AV) and outflow tract (OFT) cushions.

8 th chronic left bundle-branch block (n=8) or atrioventricular (AV) block (n=6) through atrial (A), ri

9 n atrial fibrillation (AF) without producing atrioventricular (AV) block remains a clinical challenge

10 f congenital or childhood nonimmune isolated atrioventricular (AV) block remains unknown.

11 genital heart defects, including progressive atrioventricular (AV) block requiring pacemaker implanta

12 particle image velocimetry (PIV) across the atrioventricular (AV) canal, revealing an increase in bo

13 ) and pressure gradients (nablaP) across the atrioventricular (AV) canal.

14 Atrioventricular (AV) conduction disturbances requiring

15 on (LBBB) and during biventricular pacing at atrioventricular (AV) delays of 40 ms, 120 ms, and separ

16 tion), the LV was paced over a wide range of atrioventricular (AV) delays.

17 of SSS in humans, including bradycardia and atrioventricular (AV) dysfunction (heart block).

18 The influence of atrioventricular (AV) interaction on mitral valve closur

19 Inappropriately programmed sensed and paced atrioventricular (AV) intervals (SAV/PAV) accounted for

20 ion as the leading cardiac pacemaker and the atrioventricular (AV) junction as a subsidiary pacemaker

21 cells (EPDCs) have demonstrated that at the atrioventricular (AV) junction EPDCs contribute to the m

22 The atrioventricular (AV) junction plays a critical role in

23 ntributing to the longitudinal motion of the atrioventricular (AV) plane.

24 pment is associated with the pathogenesis of atrioventricular (AV) septal defect.

25 cases), ictal bradycardia (25 cases), ictal atrioventricular (AV)-conduction block (11 cases), posti

26 f ablation (82% versus 97%; P=0.04), risk of atrioventricular block (14 versus 0%; P=0.004), and need

27 (five [1%] vs one [<0.5%]), and first-degree atrioventricular block (17 [5%] vs seven [2%]).

28 es associated with intermittent or permanent atrioventricular block (any degree).

29 al dominant sinus node dysfunction (SND) and atrioventricular block (AVB) and to characterize the mut

30 Torsades de pointes (TdP) +/-2 degrees atrioventricular block (AVB) are not always attributed t

31 nized rats and from patients with idiopathic atrioventricular block (AVB) in comparison to sera from

32 When complete atrioventricular block (AVB) occurs, infranodal escape r

33 ere limited to the occurrence of high-degree atrioventricular block (AVB) or severe symptomatic brady

34 CS patients presenting with either advanced atrioventricular block (AVB) or ventricular tachycardia

35 ably expressed and may cause cardiomyopathy, atrioventricular block (AVB), or atrial arrhythmias (AAs

36 mines the risk for torsade de pointes during atrioventricular block (AVB).

37 icular Pacing in Heart Failure Patients with Atrioventricular Block (BLOCK HF) trial randomized patie

38 te to cardiomyopathy, the impact of complete atrioventricular block (cAVB) on heart failure (HF) deve

39 ting fetal LQTS arrhythmias: TdP+/-2 degrees atrioventricular block (group 1, n=7), isolated 2 degree

40 lar block (group 1, n=7), isolated 2 degrees atrioventricular block (group 2, n=4), and sinus bradyca

41 acing was permanent atrial fibrillation with atrioventricular block (n=22, 67%).

42 riable analysis revealed that periprocedural atrioventricular block (odds ratio, 6.29; 95% confidence

43 icular Pacing in Heart Failure Patients With Atrioventricular Block [BLOCK HF]; NCT00267098).

44 ildren (aged <18 years) from 21 centers with atrioventricular block and a structurally normal heart u

45 istics on adenosine dose required to produce atrioventricular block and duration of effect were also

46 y to acquired torsades de pointes in chronic atrioventricular block and for comparison.

47 al right ventricular pacing in patients with atrioventricular block and left ventricular systolic dys

48 with biventricular pacing for patients with atrioventricular block and LV systolic dysfunction.

49 sus dofetilide in dogs with chronic complete atrioventricular block and myocardial hypertrophic remod

50 For patients with atrioventricular block and systolic dysfunction, biventr

51 dP), and in an adult woman with QTc >500 ms, atrioventricular block and TdP.

52 s before and >2 weeks after the induction of atrioventricular block and ventricular and atrial electr

53 atrial tachypacing (400 bpm for 1 week, with atrioventricular block and ventricular pacing at 80 bpm)

54 Whereas all (n=14) chronic atrioventricular block animals exhibited torsades de poi

55 Sick sinus syndrome and atrioventricular block are common clinical problems, oft

56 out biventricular pacing in HF patients with atrioventricular block because they are typically exclud

57 In chronic atrioventricular block dogs, SEA-0400 treatment is effec

58 ed against dofetilide-induced TdP in chronic atrioventricular block dogs.

59 h of acquired and often reversible causes of atrioventricular block in childhood.

60 tion because of a presumed risk of prolonged atrioventricular block in denervated hearts.

61 Adenosine induces atrioventricular block in healthy pediatric and young ad

62 There was no permanent atrioventricular block in patients who underwent cryoabl

63 five (1%) versus one (<1%), and first-degree atrioventricular block in three (1%) versus six (1%).

64 ntly predicted the adenosine dose to produce atrioventricular block or duration of effect.

65 e (n=35), 31.4% had newly diagnosed advanced atrioventricular block or severe bradycardia before TAVR

66 (AF)/atrial tachycardia (AT) in 28, advanced atrioventricular block or severe bradycardia in 24, nons

67 ars) with cardioinhibitory syncope, advanced atrioventricular block or sinus arrest, and no structura

68 monitoring showed no increased incidence of atrioventricular block or sinus pause with ozanimod.

69 ugh evaluation is required to determine when atrioventricular block requires treatment.

70 -onset left bundle-branch block and advanced atrioventricular block requiring permanent pacemaker imp

71 node dysfunction, whereas preexcitation and atrioventricular block reveal abnormalities in the atrio

72 The median longest atrioventricular block was 1.9 seconds (interquartile ra

73 Out of 7 irradiated animals, complete atrioventricular block was achieved in 6 animals of all

74 n following a dose-escalation protocol until atrioventricular block was achieved.

75 Atrioventricular block was observed in 77 patients (96%;

76 Complete atrioventricular block was present in 11 patients; 3 pat

77 ons at other anatomic sites, and no cases of atrioventricular block were encountered.

78 lly, PR interval prolongation and high-grade atrioventricular block were exclusively associated with

79 No late complications including atrioventricular block were noted.

80 ymptom onset in Killip class I to II without atrioventricular block were randomized 1:1 to IV metopro

81 icular Pacing in Heart Failure Patients With Atrioventricular Block) trial demonstrated that biventri

82 trial premature beats, sinoatrial block, and atrioventricular block, accompanied by concurrent increa

83 ion, (2) early-onset atrial fibrillation and atrioventricular block, and (3) left ventricular noncomp

84 t ventricular arrhythmia, cardiogenic shock, atrioventricular block, and reinfarction at 24 hours in

85 al duration prolongation, occasionally a 2:1 atrioventricular block, and slowing of conduction veloci

86 art disease, pacemaker, atrial fibrillation, atrioventricular block, and those using beta-blockers or

87 In the same animals at chronic atrioventricular block, AZD1305 increased the QT interva

88 ores an adequate heart rate in patients with atrioventricular block, but high percentages of right ve

89 e torsades de pointes (TdP) and/or 2 degrees atrioventricular block, but sinus bradycardia, defined a

90 , cardiogenic shock, ventricular arrhythmia, atrioventricular block, cardiac arrest, or death of a ca

91 ck (BLOCK HF) trial randomized patients with atrioventricular block, New York Heart Association sympt

92 The BLOCK HF trial randomized patients with atrioventricular block, NYHA symptom class I to III hear

93 In children with complete atrioventricular block, pacing-induced dyssynchrony last

94 including bradycardic events, sinus pauses, atrioventricular block, premature ventricular contractio

95 tion are ventricular arrhythmias or complete atrioventricular block, presenting clinically as syncope

96 isease, PR interval prolongation, high-grade atrioventricular block, significant left ventricular dys

97 dditional patients, during adenosine-induced atrioventricular block, the minimum CF significantly inc

98 model of proarrhythmia, the dog with chronic atrioventricular block, we investigated whether combined

99 bradycardia due to sinus node dysfunction or atrioventricular block.

100 ted VT reinduction with anticipated complete atrioventricular block.

101 ERT2) mice show episodes of sinus pauses and atrioventricular block.

102 use, macrophage ablation induces progressive atrioventricular block.

103 including torsades de pointes and 2 degrees atrioventricular block.

104 by atrial tachypacing (35+/-3 days) without atrioventricular block.

105 ave increased risk of procedural failure and atrioventricular block.

106 patients who had indications for pacing with atrioventricular block; New York Heart Association (NYHA

107 Atrioventricular blocked dogs were immunosuppressed, ins

108 (LBB) or left ventricular (LV) epicardium of atrioventricular-blocked dogs.

109 constructs into the left bundle branches of atrioventricular-blocked dogs.

110 PAF1C results in abnormal development of the atrioventricular boundary of the heart.

111 cle exit of TBX3+ myocytes in the developing atrioventricular bundle during the period of atrioventri

112 ide-gated channel, subtype 4 staining in the atrioventricular bundle, but has no significant effect o

113 s more cranial in the pSHF contribute to the atrioventricular canal (AVC) and atria, whereas those mo

114 in the proximal outflow tract (pOFT) but not atrioventricular canal (AVC) cushions.

115 Proper patterning of the atrioventricular canal (AVC) is essential for delay of e

116 We identified atrioventricular canal 1 (avc1), a mouse mutation that c

117 Loss of RhoU function recapitulated the atrioventricular canal and cardiac looping defects obser

118 ing pathways resulted in failure to form the atrioventricular canal and loop the linear heart tube.

119 tation frozen ventricle (frv) causes ectopic atrioventricular canal characteristics in the ventricula

120 Snai1 overexpression studies in atrioventricular canal collagen I gel explants indicate

121 h homologue dachsous1b resulted in a cardiac atrioventricular canal defect that could be rescued by w

122 Wnt signaling, which has been implicated in atrioventricular canal development (Verhoeven et al., 20

123 rhgef7b/Pak kinase pathway in order to guide atrioventricular canal development and cardiac looping.

124 a role of frv in the regional restriction of atrioventricular canal differentiation.

125 nd discovered that RhoU was expressed at the atrioventricular canal during the time when it forms.

126 In the mutant, the expressions of the atrioventricular canal marker genes, such as tbx2b, hyal

127 dant function in the endocardium to regulate atrioventricular canal morphogenesis and outflow tract f

128 endocardial endothelial cells that line the atrioventricular canal undergo an EndMT to form the endo

129 , may regulate the expression of RhoU at the atrioventricular canal.

130 ube, and communicate during formation of the atrioventricular canal.

131 al cells derived from the endocardium at the atrioventricular canal.

132 s coordinate cell junction formation between atrioventricular cardiomyocytes to promote cell adhesive

133 Net atrioventricular compliance (Cn) has been reported to be

134 one made during pacing to measure changes in atrioventricular conduction (P-R interval) independent o

135 entricular rate (p < 0.001) and reduced both atrioventricular conduction (PR segment-p = 0.02; PR int

136 on of NKX2-5 is linked to septal defects and atrioventricular conduction abnormalities, early lethali

137 tion during arrhythmias, including accessory atrioventricular conduction activation.

138 onduction system abnormalities with aberrant atrioventricular conduction and an increased rate of arr

139 imaging, to assess Ca(2+) handling, revealed atrioventricular conduction and excitation-contraction w

140 We conclude that while CVMs controlling atrioventricular conduction are distributed with a peak

141 Atrioventricular conduction block and arrhythmias caused

142 ay contribute to paravalvular regurgitation, atrioventricular conduction block, and mitral or coronar

143 ate heart rate variability, sinus pause, and atrioventricular conduction block.

144 e that most commonly involves some degree of atrioventricular conduction blockade.

145 dysfunction manifested by atropine-sensitive atrioventricular conduction blocks and bradycardia that

146 owing seizures, SENP2-deficient mice develop atrioventricular conduction blocks and cardiac asystole.

147 entricular arrhythmias, atrial fibrillation, atrioventricular conduction defects, and death by 4 mont

148 ands and family members was characterized by atrioventricular conduction disturbances (61% and 44%, r

149 ate, only a few genes for familial sinus and atrioventricular conduction dysfunction are known, and t

150 RATIONALE: Familial sinus node and atrioventricular conduction dysfunction is a rare disord

151 Transplantation of EECTs in vivo restored atrioventricular conduction in a rat model of complete h

152 of the carboxyl zinc-finger of Gata6 alters atrioventricular conduction in postnatal life as assesse

153 tionally selective effects on heart rate and atrioventricular conduction in the rat.

154 Maximal changes in atrioventricular conduction resulted from more rostral s

155 d synergize to activate transcription in the atrioventricular conduction system.

156 Overall, the ratio of the change in atrioventricular conduction to the change in heart rate

157 Delivery of 130 Gy caused disturbance of atrioventricular conduction with transition into complet

158 5 in the myocardium leads to prolongation of atrioventricular conduction, due in part to activation o

159 lrhodopsin-2-expressing macrophages improves atrioventricular conduction, whereas conditional deletio

160 ges and congenital lack of macrophages delay atrioventricular conduction.

161 ncreased left ventricle diameter and delayed atrioventricular conduction.

162 TAVI is associated with atrioventricular-conduction abnormalities requiring PPM

163 e ventricular insertion site of an accessory atrioventricular connection.

164 Impaired atrioventricular coupling and lower LA compliance correl

165 However, atrioventricular coupling was impaired and the curviline

166 and diastolic LA chamber stiffness, impaired atrioventricular coupling, and decreased left ventricula

167 rantly formed right ventricles and defective atrioventricular cushion formation.

168 Migration of EPDCs into the atrioventricular cushion mesenchyme commences around ED1

169 lar precursors give rise to the endocardium, atrioventricular cushions and coronary vascular endothel

170 n the leaflets which derive from the lateral atrioventricular cushions.

171 had an atriofascicular pathway, 1 had a long atrioventricular DAP, and 4 had a short atrioventricular

172 sal and ejection flow would occur at optimal atrioventricular delay (AVD), contributing to its hemody

173 During variation of atrioventricular delay while LV pacing, and ventriculo-v

174 n was compared with the AAI mode at multiple atrioventricular delays (AVD).

175 Four atrioventricular delays were tested.

176 Three of the 4 tachycardias had atrioventricular dissociation ruling out extranodal acce

177 ield, pharyngeal endoderm, outflow tract and atrioventricular endocardial cushions and post-migratory

178 long atrioventricular DAP, and 4 had a short atrioventricular fiber.

179 curred at right atrium (N=105, 48%) and left atrioventricular groove (N=67, 31%), followed by Bachman

180 he right atrium, Bachmann's bundle, the left atrioventricular groove, and the pulmonary vein area was

181 nt steps for first, second, and third-degree atrioventricular heart block in pediatric patients.

182 showed major mechanical dyssynchrony at left atrioventricular, interventricular, and left intraventri

183 ither sham irradiation or irradiation of the atrioventricular junction (55, 50, 40, and 25 Gy).

184 evelopmental processes that occur within the atrioventricular junction (AVJ) of the heart: conduction

185 ardia mechanism to restore sinus rhythm, and atrioventricular junction ablation with permanent pacema

186 radiation for catheter-free ablation of the atrioventricular junction in intact pigs.

187 Gy were applied in forced-breath-hold to the atrioventricular junction, left atrial pulmonary vein ju

188 entricular block reveal abnormalities in the atrioventricular junction.

189 ibrillation (AF), the safety and efficacy of atrioventricular nodal ablation (AVNA) versus pharmacoth

190 acemaker current (If; Hcn4) is suppressed in atrioventricular nodal cells, accounting for the observe

191 antation and if it was effective in blocking atrioventricular nodal conduction in these patients.

192 is followed by an increase in heart rate and atrioventricular nodal conduction properties and might b

193 that, however, showed stronger impairment of atrioventricular nodal conduction than the single Cx45-d

194 in dormant AP conduction times shorter than atrioventricular nodal conduction times before adenosine

195 Of these, 50% recovered atrioventricular nodal conduction within 1 month; 2 pati

196 nt mice were viable but showed a decrease in atrioventricular nodal conductivity.

197 n the ECG reflects atrial depolarization and atrioventricular nodal delay which can be partially diff

198 12-lead ECG, reflects the duration of atrial/atrioventricular nodal depolarization.

199 The recovery of atrioventricular nodal function after CIHB is high and f

200 ad been either SP ablation (no residual dual atrioventricular nodal physiology) or SP modulation (res

201 Atrioventricular nodal radiofrequency ablation (AVNA) wi

202 evidence that atypical fast-slow and typical atrioventricular nodal re-entrant tachycardia (AVNRT) do

203 ause of its low prevalence, data on atypical atrioventricular nodal reentrant tachycardia (AVNRT) are

204 Atrioventricular nodal reentrant tachycardia (AVNRT) is

205 ting pathway (SP) is treatment of choice for atrioventricular nodal reentrant tachycardia (AVNRT).

206 y was performed on patients with CHD who had atrioventricular nodal reentrant tachycardia and were tr

207 Atrioventricular nodal reentrant tachycardia can complic

208 SR), differentiates NF reentrant tachycardia/atrioventricular nodal reentrant tachycardia from perman

209 cating tachycardia, NF reentrant tachycardia/atrioventricular nodal reentrant tachycardia had longer

210 The relationship of atrioventricular nodal reentrant tachycardia to congenit

211 Nineteen patients with 20 SVTs (atypical atrioventricular nodal reentrant tachycardia without [n=

212 trioventricular reciprocating tachycardia or atrioventricular nodal reentrant tachycardia), excluding

213 Compared with atrioventricular nodal reentrant tachycardia, ORT patien

214 receding atrial reset was observed in 98% of atrioventricular nodal reentries during 4+/-1.1 cycles;

215 We analyzed 51 atypical atrioventricular nodal reentry (45% posterior type) and

216 a effectively distinguishes between atypical atrioventricular nodal reentry and atrioventricular reen

217 septal accessory pathways (AP) and atypical atrioventricular nodal reentry can be challenging.

218 n = 25) or focal atrial tachycardia (n = 8), atrioventricular nodal reentry tachycardia (n = 13), ree

219 ia mechanisms were seen in 3 of the 4 cases (atrioventricular nodal reentry tachycardia [2] and atrio

220 coexisted with other tachycardia mechanisms (atrioventricular nodal reentry tachycardia and atriovent

221 emonstrate the feasibility of high frequency atrioventricular-nodal stimulation (AVNS) to reduce the

222 lude injury of the sinoatrial node (SAN) and atrioventricular node (AVN), requiring cardiac rhythm ma

223 of interconnected structures, including the atrioventricular node (AVN), the central connection poin

224 Fourteen piglets 8 weeks of age underwent atrioventricular node ablation and were paced from eithe

225 Patients with cAVB were identified by an atrioventricular node ablation or diagnosis of third-deg

226 G telemetry devices underwent radiofrequency atrioventricular node ablation to produce AVB.

227 s, beam positions, and particle numbers) for atrioventricular node ablation was conducted.

228 Atrioventricular node ablation with pacemaker insertion

229 gation, we tested the feasibility of in vivo atrioventricular node ablation, in Langendorff-perfused

230 ial fibrillation should be considered before atrioventricular node ablation.

231 ck-down of Prox1 restored the anatomy of the atrioventricular node and His-Purkinje network both of w

232 uired for optimal impulse propagation in the atrioventricular node and stabilizes the level of the co

233 mitral) AT that can be overcome by injecting atrioventricular node blockers and signal averaging, res

234 lopment and postnatal function of the murine atrioventricular node by promoting cell-cycle exit of sp

235 tly higher expressed in the right atrium and atrioventricular node compared with left ventricle (P=5.

236 atrioventricular bundle during the period of atrioventricular node specification, which results in fe

237 d channel, subtype 4 staining in the compact atrioventricular node with some retention of hyperpolari

238 atients with double firing properties of the atrioventricular node, separating these into discrete ty

239 ate electrical conduction through the distal atrioventricular node, where conducting cells densely in

240 Diagnosing atypical atrioventricular node-dependent long RP supraventricular

241 the remaining 7 for pathway proximity to the atrioventricular node.

242 observed in the conduction properties of the atrioventricular node.

243 t half maximum of 10 mm was delivered to the atrioventricular node.

244 via an accessory pathway (n = 4) or via twin atrioventricular nodes (n = 4), ventricular tachycardia

245 disease) with syncope of unknown origin and atrioventricular or sinoatrial block lasting >10 seconds

246 cating tachycardia [ORT] using a decremental atrioventricular [permanent form of junctional reciproca

247 RR interval was not available) or inducible atrioventricular re-entrant tachycardia.

248 icenter study of infants <4 months with SVT (atrioventricular reciprocating tachycardia or atrioventr

249 ) had benign recurrence, including sustained atrioventricular reentrant tachycardia (132 patients) or

250 entricular nodal reentry tachycardia [2] and atrioventricular reentrant tachycardia [1]).

251 ay antegrade refractory period (P<0.001) and atrioventricular reentrant tachycardia initiating atrial

252 atypical atrioventricular nodal reentry and atrioventricular reentrant tachycardia mediated by septa

253 this phenomena was observed in 6 (8%) of the atrioventricular reentrant tachycardia mediated by septa

254 ptomatic Wolff-Parkinson-White patients with atrioventricular reentrant tachycardia referred for elec

255 ay effective refractory period (P<0.001) and atrioventricular reentrant tachycardia triggering sustai

256 d multiple accessory pathways (P<0.001), and atrioventricular reentrant tachycardia triggering sustai

257 rioventricular nodal reentry tachycardia and atrioventricular reentrant tachycardia).

258 and 13 had frequent symptomatic episodes of atrioventricular reentrant tachycardia.

259 n shown to result in abnormal development of atrioventricular septa.

260 and management of right dominant unbalanced atrioventricular septal defect (AVSD) remains challengin

261 a group of individuals with DS and complete atrioventricular septal defect and sequenced 2 candidate

262 es for CHD: CRELD1, which is associated with atrioventricular septal defect in people with or without

263 Atrioventricular septal defects (AVSD) are the most comm

264 Atrioventricular septal defects (AVSDs) are a common sev

265 Nonsyndromic atrioventricular septal defects (AVSDs) are an important

266 Also detected by micro-CT were atrioventricular septal defects (n=22), tricuspid hypopl

267 ariable in patients with CHD7 mutations, but atrioventricular septal defects and conotruncal heart de

268 Conotruncal defects and atrioventricular septal defects are over-represented in

269 ata4 and Smad4 genetically interact in vivo: atrioventricular septal defects result from endothelial-

270 mmon CHD observed, whereas outflow tract and atrioventricular septal defects were the most prevalent

271 th a pleitropic syndrome of progressive RCM, atrioventricular septal defects, and a high prevalence o

272 eat arteries, double-outlet right ventricle, atrioventricular septal defects, and caval vein abnormal

273 ng with diverse cardiac anomalies, including atrioventricular septal defects, Ebstein malformation of

274 enchymal protrusion, and partially penetrant atrioventricular septal defects, including ostium primum

275 and that Id2 deficiency in mice could cause atrioventricular septal defects.

276 d heart field (SHF) are required for OFT and atrioventricular septation and OFT alignment.

277 cardium with reduced cell proliferation, and atrioventricular septation defects similar to Gata4;Tbx5

278 ocyte proliferation, outflow tract (OFT) and atrioventricular septation, and OFT alignment.

279 nts that are essential for outflow tract and atrioventricular septation.

280 We identified an atrioventricular-specific enhancer and a pan-cardiac enh

281 ive small GTPases, RhoA and Rac1, coordinate atrioventricular valve (AV) differentiation and morphoge

282 1 is necessary for proper development of the atrioventricular valve (AV).

283 Previous work has highlighted atrioventricular valve (AVV) index as a reasonable defin

284 monary bypass time, operation prior to 1991, atrioventricular valve (AVV) replacement at the time of

285 tion fraction (SVEF) at the time of systemic atrioventricular valve (SAVV) replacement as a predictor

286 a low incidence of semilunar valve defects, atrioventricular valve defects and double outlet right v

287 versely affects transplant-free survival and atrioventricular valve function.

288 ediating intracellular kinase activation for atrioventricular valve morphogenesis using well defined

289 quent impact on transplant-free survival and atrioventricular valve regurgitation (AVVR) as well as t

290 Throughout the study, atrioventricular valve regurgitation (hazard ratio [HR]:

291 ventricular dysfunction, moderate or greater atrioventricular valve regurgitation on pre-catheterizat

292 ded complete heart block (n=2) and increased atrioventricular valve regurgitation requiring surgical

293 rtension, pulmonary regurgitation, pulmonary atrioventricular valve regurgitation, pulmonary and syst

294 own of the ortholog in zebrafish resulted in atrioventricular valve regurgitation.

295 temic (P=0.001), and (4) pulmonary (P=0.045) atrioventricular valve regurgitation.

296 Aortic arch and atrioventricular valve reinterventions were not differen

297 ived cells to the individual leaflets of the atrioventricular valves has also important pragmatic con

298 tion of EPDCs to the various leaflets of the atrioventricular valves provides a new paradigm in valve

299 lar myocardial wall and malformations of the atrioventricular valvuloseptal complex.

300 r rare genetic variants in genes involved in atrioventricular valvuloseptal morphogenesis contribute