ライフサイエンスコーパス: atrophic

1 , although some nerves lost axons and became atrophic.

2 agina of the MOER female mice were extremely atrophic.

3 ixels without increased FAF would not become atrophic.

4 in Phox2b heterozygous mutants it is highly atrophic.

5 ed except the thymus, which surprisingly was atrophic.

6 undergo premature growth arrest, and become atrophic.

7 arrest, fail to redifferentiate, and become atrophic.

8 0.59%-1.55%) of nonindigenous participants (atrophic, 0.72%; neovascular, 0.24%).

9 Mesh herniorrhaphy more completely reverses atrophic abdominal wall changes than primary herniorrhap

10 pulsed-dye lasers (PDLs) have been used for atrophic acne scarring, and anecdotal experience suggest

11 RNFL is partially spared in atrophic advanced AMD.

12 Atrophic age-related and juvenile macular degeneration a

13 ular dystrophy (age >18 years) and nine with atrophic age-related macular degeneration (age >55 years

14 ipofuscin is associated with pathogenesis of atrophic age-related macular degeneration (AMD) and Star

15 rophy (GA) is the end-stage manifestation of atrophic age-related macular degeneration (AMD).

16 Such adducts may contribute to diseases like atrophic age-related macular degeneration (AMD).

17 receptor degenerative conditions like RP and atrophic age-related macular degeneration (AMD).

18 ) transplantation is a promising therapy for atrophic age-related macular degeneration (AMD); however

19 onths after transplantation in patients with atrophic age-related macular degeneration and 8-20 point

20 he retina is associated with pathogenesis of atrophic age-related macular degeneration and Stargardt

21 seases such as retinitis pigmentosa (RP) and atrophic age-related macular degeneration.

22 ases including retinitis pigmentosa (RP) and atrophic age-related macular degeneration.

23 atients with exudative AMD, 46 patients with atrophic AMD and 111 healthy controls.

24 Patients with advanced atrophic AMD carried these rare variants more frequently

25 progressively thinner up to neovascular and atrophic AMD groups (P < .0001).

26 cantly vary among AREDS category 2 and 3 and atrophic AMD groups, compared to controls.

27 mpared with healthy controls (P < 0.001) and atrophic AMD patients (P < 0.001).

28 e eye from each of 42 patients with early or atrophic AMD) were divided into four groups: 14 with dru

29 category 3, 26 for neovascular AMD, 26 with atrophic AMD, and 26 controls.

30 In advanced atrophic AMD, FIAF is found mostly adjacent to drusen an

31 neration (AMD) are limited, particularly for atrophic AMD, the identification of predisposing genetic

32 rove understanding of the pathophysiology of atrophic AMD.

33 cytotoxic functions for endogenous dsRNAs in atrophic AMD.

34 n of RPC survival in future cell therapy for atrophic AMD.

35 category 2 and 3, naive neovascular AMD, and atrophic AMD.

36 4%-0.63%]) indigenous participants had late (atrophic) AMD.

37 ormal at 20 weeks, but by 30 weeks, 56% were atrophic and 25% of glomeruli were atubular; glomerulotu

38 The brains were moderately to severely atrophic and atrophy was particularly obvious in the cer

39 (GalphasL) G-protein subunits produced minor atrophic and hypertrophic changes in muscle mass, respec

40 l was observed in all PanIN lesions, whereas atrophic and inflammatory ductal lesions retained normal

41 H. felis-infected wild-type mice had severe atrophic and metaplastic mucosal changes.

42 This study has demonstrated progressive atrophic and microstructural changes across the sensory

43 Extensive upstream atrophic and microstructural changes of corticospinal ax

44 e in rates of ripple discharge between local atrophic and nonatrophic areas.

45 generated, and in each line the pancreas was atrophic and occasionally showed dilation of pancreatic

46 ilitate both proliferation and DNA damage in atrophic and PIN cells.

47 number of small fibers corresponding to both atrophic and regenerating fibers were observed.

48 within the collapsed OPL, although both are atrophic and the spatial distribution of the pedicles is

49 biopsies showed a focal increase of TIA1 in atrophic and vacuolated fibers.

50 On examination, he was severely atrophic and weak in his shoulder girdle and the entire

51 th diabetes mellitus, Schwann tubes appeared atrophic and were limited to the mid-dermis.

52 onfluent PPA patients, the posterior IFC was atrophic and, unlike controls, showed an equivalent leve

53 vitelliform, pseudohypopyon, vitelliruptive, atrophic, and cicatricial) identified no pattern as stag

54 ior, inferior, and middle temporal gyri were atrophic, and subjacent white matter was gliotic.

55 Two patients showed an atrophic-appearing macular lesion.

56 Atrophic AQM myofibers showed coexpression of TGF-beta r

57 rames, FA displayed hyperfluorescence in the atrophic area in 100% (n = 20) of eyes affected by GA an

58 ied above the Bruch membrane line within the atrophic area in the SD-OCT images.

59 The mean atrophic area increased by 0.37 mm(2) in the hyper-FAF s

60 The atrophic area of the retinal pigment epithelium assessed

61 the hyporeflective band, already within the atrophic area.

62 standard deviation) rate of increase in pure atrophic areas (no subretinal material) was 0.7 +/- 0.8

63 IL expression was restricted to regenerating/atrophic areas of muscle fascicles, blood vessels, and i

64 st and most variable immediately adjacent to atrophic areas.

65 d loss of outer retinal structure within the atrophic areas.

66 tions and treatment changes; those that were atrophic at the final visit (30.8%) had a worse initial

67 malities are the result of a morphologically atrophic AV node.

68 assays showed high fat-fed mice had greater atrophic capillaries, pericyte ghosts, and permeability

69 lular localization of critical RPE proteins, atrophic cell extrusions into the subretinal space, and

70 e further demonstrate that the p53 gene from atrophic cells expressing TAg is wild type, whereas tumo

71 uggesting that TAg may inactivate p53 in the atrophic cells.

72 s characterized by keratotic lesions with an atrophic center encircled by a prominent peripheral ridg

73 without polymicrogyria or heterotopia; (ii) atrophic cerebellar hemispheres with stunted folia, prof

74 Axonal degeneration of the CST in the atrophic cervical cord, proximal to the site of injury,

75 We examined how atrophic change in the cerebellum impacts functional con

76 We hypothesize that these atrophic changes decrease muscle elastic properties and

77 submacular lesions resulted in outer retinal atrophic changes in all 3 eyes.

78 Pathophysiological and atrophic changes in the cerebellum are documented in Par

79 All tested agents partially prevented atrophic changes in the Rdh8(-/-)Abca4(-/-) retina with

80 Atrophic changes in the retinal vasculature are also obs

81 e excess motoneurons remained viable without atrophic changes in the ZPK/DLK-deficient mice surviving

82 These data indicate that profound atrophic changes occur in cholinergic systems of the LDT

83 ociated with a greater visual gain and fewer atrophic changes over a 12-month follow-up.

84 of axonal elongation during regeneration and atrophic changes that occur in denervated Schwann cells

85 specific changes across the neuroaxis (i.e., atrophic changes versus increases in volume) and may pro

86 evident in 38%, whilst multifocal, focal, or atrophic changes were seen in 7%, 33% and 9% respectivel

87 cular choroidal inflammatory infiltrate, and atrophic changes within the optic nerve were consistentl

88 y (SCI) has been shown to trigger structural atrophic changes within the spinal cord and brain.

89 aded skeletal muscles undergo characteristic atrophic changes, including change in fiber type composi

90 nd disease progression, while sd-OCT reveals atrophic changes.

91 plasmosis syndrome classically presents with atrophic choroidal scars, which are thought to progress

92 The C3KO mice were atrophic containing small foci of muscular necrosis.

93 ncreas-specific disruption of Atg5 developed atrophic CP, independent of beta-cell function; a greate

94 se may thus serve as a model for age-related atrophic degeneration of the RPE, including the dry type

95 ds, in Crxp-Nrl transgenic mice, produces an atrophic dendritic field yet leaves the axon terminal sy

96 boundary of CNV defined at baseline, termed "atrophic disciform scars," developed in 5 eyes (6%), all

97 drusen-associated lipofuscin is a marker of atrophic disease progression.

98 These include early, intermediate, and atrophic disease stages.

99 iant appears to play a role in exudative and atrophic disease, whereas the ELOVL4 variant may play a

100 al therapeutic applications in children with atrophic disorders such as lipoatrophy and morphea.

101 These temporal regions were not atrophic, displayed normal evoked magnetic and electrica

102 ilated biliary and pancreatic ducts (n = 1), atrophic distal pancreatic parenchyma (n = 3), and mass

103 tumors, indirect signs such as mass effect, atrophic distal parenchyma, and an interrupted duct sign

104 get, was increased and accumulated in highly atrophic DM2 muscle fibers.

105 d the clinical heart failure field, and anti-atrophic drugs have been used to enhance the cardiac rec

106 l cell compartment did not expand and became atrophic during uterine development in these mice.

107 rocured and was successfully grafted into an atrophic edentulous ridge.

108 ng transforming growth factor-beta1-mediated atrophic effects in inflammation-induced atrophy.

109 non-PCa cells (either inflammatory cells or atrophic epithelial cells) or by affecting a COX-2-indep

110 These data support the hypothesis that atrophic epithelium in a subset of PIA lesions may lead

111 eared not to contribute to the repair of the atrophic epithelium.

112 ation shows the presence of BKV sequences in atrophic epithelium.

113 ing muscle mass by controlling expression of atrophic factors like Mstn and activin.

114 ts appeared smaller at 10 weeks; by 12 weeks atrophic fibers were more prevalent than in age-matched

115 llary and transverse vessel densities in non-atrophic fibre regions were not significantly different

116 s, a variation in myofibre size and/or small atrophic fibres.

117 Gastric premalignant conditions, atrophic gastritis (AG) and intestinal metaplasia (IM) a

118 biopsy specimens from 74 patients, including atrophic gastritis (AG) cases without aspirin use (contr

119 on host biology-the transition from chronic atrophic gastritis (ChAG) to gastric adenocarcinoma-and

120 er, a subset of individuals develops chronic atrophic gastritis (ChAG), a condition characterized in

121 Chronic atrophic gastritis (ChAG), a Helicobacter pylori-associa

122 hat develop an antecedent condition, chronic atrophic gastritis (ChAG).

123 ive once preneoplastic lesions of multifocal atrophic gastritis (MAG) and intestinal metaplasia (IM)

124 ces gastric cancer risk in patients with non-atrophic gastritis (NAG), and is ineffective once preneo

125 as an efficient model for the development of atrophic gastritis after infection and to determine the

126 e associated with hypergastrinaemia, chronic atrophic gastritis and achlorhydria.

127 NS-GAS and B6 wild-type mice had both severe atrophic gastritis and corpus dysplasia, while GAS-KO mi

128 d characteristictly found in assciation with atrophic gastritis and gastric cancer consistent with Bh

129 The high incidence of atrophic gastritis and gastric cancer suggest the phylog

130 ze the human stomach and have been linked to atrophic gastritis and gastric carcinoma.

131 ting gastrin levels, and develop spontaneous atrophic gastritis and gastrointestinal intraepithelial

132 Decreased Bcl-2 gene expression signified atrophic gastritis and IM in presence of cancer, as well

133 how helminth coinfection may protect against atrophic gastritis and T helper type 1 responses.

134 ; 2) gastric IM adjacent to a GU but with no atrophic gastritis changes; 3) patients receiving H. pyl

135 sia (SPEM) develops in patients with chronic atrophic gastritis due to infection with Helicobacter py

136 rent study tests the hypothesis that chronic atrophic gastritis from hypochlorhydria in the gastrin-d

137 The atrophic gastritis in the infected wild-type mice, parti

138 gastric cancer (GC) and adjacent mucosa with atrophic gastritis or intestinal metaplasia (AG/IM GC+),

139 stinal metaplasia (AG/IM GC+), as well as in atrophic gastritis or intestinal metaplasia mucosa of pa

140 otic transgenic mouse model of human chronic atrophic gastritis, a preneoplastic condition.

141 We evaluated 19 superficial gastritis, 18 atrophic gastritis, and 18 intestinal metaplasia from ca

142 included, of which 37 were cases of chronic atrophic gastritis, intestinal metaplasia, or dysplasia.

143 postulated to initiate a progression through atrophic gastritis, metaplasia and dysplasia to cancer,

144 gnificantly increases the risk of developing atrophic gastritis, peptic ulcer disease, and gastric ad

145 redominantly in tissues showing gastritis or atrophic gastritis.

146 strains isolated from patients with chronic atrophic gastritis.

147 otential concern in patients with autoimmune atrophic gastritis.

148 circumvent the pH alteration resulting from atrophic gastritis.

149 Atrophic glands also showed evidence of epithelial plugg

150 wed foci of tumor with congested tubules and atrophic glomeruli.

151 Her final diagnoses were atrophic glossitis and glossodynia secondary to vitamin

152 hogenic mechanisms of nutrient deficiency in atrophic glossitis are discussed.

153 ound in only 14 of 166 eyes of the early and atrophic groups.

154 n and the LOXL protein in the heart, dermis, atrophic hair follicles, and sebaceous glands.

155 geal arches (PA2s) and is associated with an atrophic heart.

156 Unlike skeletal muscle cachexia, atrophic hearts do not upregulate the ubiquitin-proteaso

157 In atrophic hearts, there was an increase in polyubiquitin

158 repsilon4 carrier status was associated with atrophic hippocampal volume (pooled SMD: -0.47; 95% CI -

159 APOE varepsilon4 was associated with atrophic hippocampal volume in MRI markers, increased ce

160 mantic dementia did not extend caudal to the atrophic/hypometabolic zone.

161 cortical atrophy, brain regions known to be atrophic in patients with autopsy-proved FTD.

162 Sebaceous glands were markedly atrophic in PP versus nonlesional psoriatic skin (91% av

163 the male secondary sex organs were absent or atrophic, including the prostate, seminal vesicle, bulbo

164 The atrophic injury seems to result from increased oxidative

165 steophytes and joint space narrowing [JSN]), atrophic (JSN without osteophytes), or osteophytic (femo

166 In contrast, atrophic kidneys beyond totally occluded renal arteries

167 yze the electrophysiologic remodeling of the atrophic left ventricle (LV) in right ventricular (RV) f

168 Atrophic lesion areas were measured by FAF and CFP to as

169 gradable fundus autofluorescence images with atrophic lesion(s) present in at least 1 eye.

170 Because these atrophic lesions are so prevalent and extensive, even th

171 Incidence of atrophic lesions as determined by fundus autofluorescenc

172 er of 300 microm, with the total area of all atrophic lesions being less than or equal to 12 mm2 in a

173 To describe the yearly progression rate of atrophic lesions in the retrospective Progression of Sta

174 arly rate of progression using the growth of atrophic lesions measured by fundus autofluorescence.

175 efined by the presence of sharply demarcated atrophic lesions of the outer retina, resulting from los

176 To examine the incidence of atrophic lesions of the retinal pigment epithelium in pa

177 onset of symptoms, 21.9 [13.3] years) showed atrophic lesions present on at least 2 visits and were g

178 peripheral pigmentary changes and clustered atrophic lesions resembling grouped congenital albinotic

179 factors by measuring the enlargement of the atrophic lesions using fundus autofluorescence (FAF) and

180 Atrophic lesions with a diffuse (mean 0.95 mm(2)) or ban

181 tions in ESCS include (1) torpedo-like, deep atrophic lesions with a small hyperpigmented rim, variab

182 ment epithelial changes; 2 (5%) had multiple atrophic lesions, extending beyond the arcades; and 1 (2

183 Although BKV DNA was found in benign and atrophic lesions, TAg and p53 coexpression was observed

184 underwent the same light treatment developed atrophic lesions.

185 Ag and p53 coexpression was observed only in atrophic lesions.

186 h fatty livers nor PARP-1-deficient mice had atrophic livers.

187 ere staining occurred primarily in basal and atrophic luminal epithelial cells.

188 ed with electrophysiologic remodeling of the atrophic LV.

189 demyelination, high MOG antibody titers and atrophic lymphoid organs.

190 Nevertheless, because of severe atrophic macular changes and subfoveal fibrosis, no impr

191 r and are associated with autosomal dominant atrophic macular degeneration (adMD/STGD3).

192 egeneration, emphasizing the dissociation of atrophic macular degeneration from generalized cone dege

193 We mapped a new X-linked recessive atrophic macular degeneration locus to Xp21.1-p11.4 and

194 ion of MFRP and to study the pathogenesis of atrophic macular degeneration.

195 Bilateral coloboma-like atrophic macular lesions were observed in 1 patient (6%)

196 ndus features of pigmentary retinopathy with atrophic macular lesions.

197 Identification of an RPGR mutation in atrophic maculardegeneration expands the phenotypic rang

198 Zone 1 (atrophic margin) sensitivity was significantly lower tha

199 re further classified as complete edentulous atrophic maxilla (CEM) and partial edentulous atrophic m

200 trophic maxilla (CEM) and partial edentulous atrophic maxilla (PEM).

201 etic rehabilitation of 10 totally edentulous atrophic maxillae after bone reconstruction with a titan

202 considered a valid option in reconstructing atrophic maxillae to allow for implant-borne prosthetic

203 Ten atrophic maxillae were reconstructed with 19 titanium me

204 Reconstruction and rehabilitation of atrophic maxillae with bone grafts is a lengthy and dema

205 ents and HCs, to detect Abeta plaques in the atrophic mesial temporal cortex, and potentially to eval

206 rowth and reinnervation of muscle targets by atrophic MNs in Bax KO mice and prevented the normal pos

207 lterations in precancerous conditions, i.e., atrophic mucosa (AM) and intestinal metaplasia (IM), in

208 iption of these atrogenes is synchronized in atrophic muscle.

209 ncreased p63 protein levels in the fibers of atrophic muscles via denervation-dependent and -independ

210 Perifascicular atrophic myofibers in DM were deficient in a number of s

211 wed deficiency of titin in DM perifascicular atrophic myofibers.

212 e cells may have a role in the prevention of atrophic non-union and could enable a paradigm shift in

213 the fracture gap to prevent the formation of atrophic non-union in a rat model.

214 Atrophic non-union is attributed to biological failure o

215 ignificant bone regeneration potential in an atrophic non-union model.

216 .0001) in callus were significantly lower in atrophic-nonunion patients than in healed-fracture patie

217 patients (41 mumol/L; P < 0.001) but not in atrophic-nonunion patients.

218 plasma and callus were measured with HPLC in atrophic nonunions (n = 12) and compared with those in h

219 Atrophic nonunions had lower concentrations of all amino

220 end-stage age-related macular degeneration (atrophic or disciform scar age-related macular degenerat

221 The atrophic pancreas contained small numbers of islets, whi

222 MDCT of the abdomen was done which revealed atrophic pancreas with organized collection in the sub-c

223 rtrophy occurs remains unknown, study of the atrophic papilla gives us a new clue for understanding t

224 The malignant form of atrophic papulosis (Kohlmeier-Degos disease) is a rare t

225 old male who first presented with cutaneous atrophic papulosis but became critically ill from small

226 and laparotomy in our patient with malignant atrophic papulosis were compared to those in the literat

227 copic and laparoscopic findings in malignant atrophic papulosis which suggest laparoscopy is the more

228 terature search using the keywords malignant atrophic papulosis, Degos disease, endoscopy, laparoscop

229 of suspicion for gastrointestinal malignant atrophic papulosis, even if endoscopic examination is no

230 anching reticular pigmentation) (22.7%), and atrophic patches (16.8%).

231 iated skin manifestations, including unusual atrophic patches with abnormal elastic fibers that can s

232 However, daily dosing activated atrophic pathways, including F-box protein 32 (Fbxo32),

233 relation to radiographic OA status, with the atrophic phenotype being defined as knees with absent or

234 A minority of knees exhibited the atrophic phenotype, which also included knees without ra

235 Twenty-one knees (1.3%) showed an atrophic phenotype.

236 phytic and composite phenotypes, but not the atrophic phenotype.

237 Most lesions presented as 2- to 15-mm, round atrophic plaques.

238 techniques are most effective for restoring atrophic posterior areas of the mandible with dental imp

239 Our objective was to determine whether the atrophic posterior IFC is differentially recruited for t

240 ne the sinus lateral wall thickness (LWT) of atrophic posterior maxilla (<10 mm) of patients with com

241 ons in the brain and cord, or an alternative atrophic process, is responsible for spinal cord atrophy

242 unction for p63 as a contributor to muscular atrophic processes via the regulation of multiple genes,

243 anabolic (or hypertrophic) and catabolic (or atrophic) processes.

244 ed by anabolic (hypertrophic) and catabolic (atrophic) processes.

245 many distinct pathways that make it a unique atrophic program.

246 isting of benign prostate (n = 108 samples), atrophic prostate (n = 26), prostatic intraepithelial ne

247 (iii) In an infant with atrophic putaminal lesions, striatal flow was normal but

248 stream components of mTOR, were activated in atrophic rat heart.

249 ntitative, dynamic visualization of cortical atrophic rates in normal elderly populations and in thos

250 y with the severity of damage in these local atrophic regions.

251 ow the normal reference range, suggesting no atrophic remodeling after prolonged LVAD unloading.

252 dine receptor were not indicative of ongoing atrophic remodeling during LVAD unloading.

253 egulators of protein synthesis in a model of atrophic remodeling induced by heterotopic transplantati

254 In a model of atrophic remodeling induced by heterotopic transplantati

255 nderlying increased protein synthesis during atrophic remodeling is not known.

256 ional regulators of protein synthesis during atrophic remodeling of the heart.

257 lated with increased muscle adipogenesis and atrophic remodeling.

258 in mass, and altered gene expression, due to atrophic remodeling.

259 d muscle recovery from injury while limiting atrophic remodeling.

260 Mechanical unloading of the heart results in atrophic remodeling.

261 nt vaginal opening, persistent diestrus, and atrophic reproductive tracts with absent corpora lutea.

262 , possibly by inducing a hypochlorhydric and atrophic response to gastric H. pylori infection.

263 Histopathology revealed severely atrophic retina.

264 ptica is one of the etiologic agents causing atrophic rhinitis and pneumonia in swine.

265 rella multocida Type D, a causative agent of atrophic rhinitis in swine and pasteurellosis in other d

266 ions, including canine kennel cough, porcine atrophic rhinitis, and a whooping cough-like disease in

267 ed in the turbinate atrophy seen in cases of atrophic rhinitis.

268 No significant geometric associations with atrophic RHOA were found.

269 presence of teeth adjacent to the edentulous atrophic ridge, and age were shown to influence maxillar

270 erimental ridge defects were created to form atrophic ridges.

271 Atrophic RPE changes included RPE thinning, RPE porosity

272 y; the other 22 patients had foveal atrophy, atrophic RPE lesions, and/or irregular yellow-white fund

273 ar histoplasmosis from the development of an atrophic scar at the fovea or following choroidal neovas

274 Fibrotic or atrophic scar present in the lesion, but not under the c

275 ur and hair loss, which were associated with atrophic sebaceous glands and fur lipid abnormalities.

276 tion showed that the testes were composed of atrophic seminiferous tubules, whereas germ cells were f

277 opose a model whereby Dex- and Mstn-mediated atrophic signals are integrated through miR1, which then

278 We studied a patient referred for unusual atrophic skin patches on the buttocks.

279 in participants who had eyes with multifocal atrophic spots compared with those with unifocal spots (

280 re was centrifugal expansion of disseminated atrophic spots, which progressed to the eventual profoun

281 nding that some tumor cells can remain in an atrophic state even in completely regressed lesions sugg

282 etal muscle atrophy in response to different atrophic stimuli in cells and in mouse models.

283 Atrophic testes and testicular degeneration were observe

284 CreERT2 lines) resulted in male infertility, atrophic testes with vacuolation, azoospermia, and sperm

285 loading of the superolateral cortex leads to atrophic thinning.

286 mination through structural connections from atrophic to unaffected cortical regions.

287 titial myofibroblasts from perivascular into atrophic tubular spaces rather than via epithelial-mesen

288 les (NT); short atrophic tubules (SAT); long atrophic tubules (LAT); atrophic tubules with no observa

289 me of cortical interstitium (P <0.00001) and atrophic tubules (P <0.01) were increased in D patients.

290 ruli attached to: normal tubules (NT); short atrophic tubules (SAT); long atrophic tubules (LAT); atr

291 Epithelium of atrophic tubules containing TR-dextran remained confined

292 The atrophic tubules display pathologically persistent signa

293 fractional volumes of proximal, distal, and atrophic tubules per cortex were estimated using appropr

294 tubules (SAT); long atrophic tubules (LAT); atrophic tubules with no observable glomerular opening (

295 Fractional volume of atrophic tubules, %AG, and percent of glomeruli with tip

296 ents were atubular, and 51% were attached to atrophic tubules.

297 0% of glomeruli were atubular or attached to atrophic tubules; in advanced disease, 100% were abnorma

298 It typically manifests as atrophic white plaques, which may be accompanied by purp

299 ed, and remaining PC soma and dendrites were atrophic, with almost complete disappearance of spiny br

300 sa (RP) and in the transitional zone (TZ) of atrophic zones (AZ), which characterize geographic atrop