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1 of fibroblast growth factor 21 in liver was attenuated.
2 ncoding of response information was strongly attenuated.
3 ynaptic LFP signals were found to be sharply attenuated.
4 ce interval, 0.96-1.35), the association was attenuated.
6 In vitro studies revealed that FTY720 also attenuated 6-OHDA- or rotenone-induced toxicity in SH-SY
7 SNL-evoked mechanical hypersensitivity was attenuated, accompanied by a partial recovery of Kv4.3,
8 nhibited proliferation of TRAMP C2 cells and attenuated activation of ERK/MAPK and the master transcr
9 A binding and transcriptional activities and attenuates adipogenesis in various genetic and cell-base
10 vaccination during 2013-14 influenza season attenuated adverse outcome among adults that were hospit
11 independent of vascular risk factors and was attenuated after adjustment for APOEepsilon4 carrier sta
12 ent for cognitive decline but was completely attenuated after adjustment for cognitive performance.
13 xposure of aged HSCs to thrombin-cleaved OPN attenuates aging of old HSCs, resulting in increased eng
14 ition of calpain using calpain knockout mice attenuated airway smooth muscle remodelling in mouse ast
16 es, to reduce HIF-1alpha level significantly attenuated albumin-induced increases in TIMP-1 and colla
21 nsin II-infused Apoe(-/-) and Ldlr(-/-) mice attenuated aneurysm formation and progression within the
22 that systemic administration of MS0021570_1 attenuates anxiety-like behavior while intra-BLA adminis
24 om S. aureus subsp. aureus strain NCTC8325-4 attenuated bacterial survival in human whole blood ex vi
26 nts.Twice daily RCE intake over 1 y potently attenuated BMD loss caused by estrogen deficiency, impro
27 tant EXO1 resulted in hyper-resection, which attenuated both NHEJ and HR and severely compromised DSB
30 s, and epithelial cell IL-25 expression were attenuated by anti-IL-33 treatment and in TSLP receptor-
32 The angiotensin II-induced hypertension was attenuated by cotreatment with the alphaAnalogue (50 nmo
33 PK signaling in HMVP2 cells, which was again attenuated by either AMD3100 or knockdown of CXCR4 or CX
35 variability on MF input selectivity will be attenuated by high levels of CGC inhibition providing fu
39 bated by allopregnanolone (10 mg/kg, IP) and attenuated by progesterone (30 mg/kg, IP) in SD-subjecte
41 covered 3-amido thiazolino 2-pyridones which attenuated C. trachomatis infectivity without affecting
42 -KIR2DP1(F) were stronger receptors than the attenuated C2-specific T44-KIR2DP1(F) encoded on CenB Th
44 mediating (1) antihypertensive effects, (2) attenuating cardiac remodeling, and (3) increasing angio
46 lent safety profile and high stability, live-attenuated CDV vaccines can retain residual virulence in
47 r cells to anoikis induction and resulted in attenuated cell invasion and elevated reactive oxygen sp
48 e arrested the progression of lung fibrosis, attenuated cellular apoptosis (caspase-3/7) and lung dep
51 ian rhythms, or hastened their recovery, and attenuated changes in mPer2 Our findings show that CSDS
53 cisive in vivo because silencing of the INSR attenuated clinical symptoms in animal models of acute g
56 Furthermore, knockdown of TLR8 completely attenuated collagen expression in monocytes exposed to H
58 d dynamics (z = 4.55; P < .001) that was not attenuated compared with controls (z = -0.42; P = .67).
59 se induced by cream cheese was significantly attenuated compared with that induced by cheddar cheese
61 Here, we demonstrated that AKG effectively attenuated corticosterone-induced protein degradation an
63 that a pathogenic SIVmac239 virus and a live-attenuated, deglycosylated mutant Delta5G virus infected
64 tegmental area (VTA) dopamine depletion had attenuated delta activity (1-4 Hz) in the medial frontal
66 the role of mesenchymal dental pulp cells in attenuating dentin resorption in homeostasis are also re
67 uced stronger CD8 responses than other, more attenuated DENV isolates.IMPORTANCE The lack of a known
69 an antagonist, or a local silencing of MKP-1 attenuates depressive-like behaviors, pointing to an imp
70 nist BMS002 protects against GFR decline and attenuates development of DN through multiple mechanisms
73 se activation, or NMDA receptors blocks this attenuating effect, indicating that the interaction betw
74 the de-neddylating COP9 signalosome (CSN) in attenuating EGFR through an association between the Cops
76 ulation during triggering stimuli appears to attenuate ERG currents, leading to membrane potential de
77 errant ERK1/2- and PI3K-mediated signalling, attenuates excessive protein synthesis and corrects dend
82 e III S. agalactiae 874391 was significantly attenuated for colonization in mice and adhesion to uroe
83 ion or altered biofilm formation, but it was attenuated for survival upon challenge by human polymorp
85 or gamma coactivator (PGC)-1alpha as well as attenuated forskolin-stimulated uncoupled respiration.
86 ray, whereas inhibiting Calcineurin activity attenuated FoxO-mediated murf1 expression and protected
87 ctive lysosomal degradation of bacteria also attenuated further phagocytosis, resulting in elevated b
90 interaction with AQP4: AQP4 internalization, attenuated glutamate uptake, intramyelinic edema, interl
94 th cAVB in the chronic phase, the effect was attenuated (hazard ratio, 1.16; 95% confidence interval,
96 summary, we demonstrated that silencing PLK2 attenuates HDG-induced podocyte apoptosis and inflammati
98 ation of lipid homeostasis was also shown to attenuate hepatocellular carcinoma (HCC) development, th
101 and highlight the potential of probiotics to attenuate high-fat diet-related metabolic disorder.
103 NAH, but does not in patients with IAH, and attenuates hypoglycemia-induced cognitive dysfunction.
104 IL-15 KO mice showed improved survival, attenuated hypothermia, and less proinflammatory cytokin
107 king both SPN and SLO production is severely attenuated in ability to resist killing by human polymor
108 ypoxia-inducible factor-1alpha induction was attenuated in AMPKalpha2-deficient cells and accompanied
109 ATII cell proliferation during repair was attenuated in ATII cell-specific HIF1alpha knockout (Sft
111 s, and mutant CrPV(R146A) virus infection is attenuated in Drosophila melanogaster S2 cells and adult
113 II neurons, but such currents were severely attenuated in gamma-2-lacking stargazer (stg/stg) mice.
115 a, C5a, and terminal C' complex (C5b-9)] was attenuated in il17a(-/-) mice, and IL-17A neutralization
116 WT kinase activity, an effect significantly attenuated in inter- or intradisulfide-deficient PKGIalp
117 pseudotuberculosis DeltarfaH strain was not attenuated in mice, suggesting that rfaH is not required
121 plasma suPAR levels: APOL1-related risk was attenuated in patients with lower suPAR, and strengthene
124 ate that a recent isolate of HFMG is greatly attenuated in the chicken host relative to the index iso
125 tingly, the ATP-induced JAZ1 degradation was attenuated in the JA receptor mutant, coi1, but not in t
128 o replicate in macrophages and were severely attenuated in their ability to generate cutaneous lesion
129 atio range, 1.30-1.92; p < 0.001), which was attenuated in those who received renal replacement thera
131 ombinant virus, rLS/AMPV-C F&G, was slightly attenuated in vivo, yet maintained similar characteristi
133 icken interferon-alpha (chIFN-alpha) and the attenuated infectious bursal disease virus vaccine strai
134 is an aryl hydrocarbon receptor ligand that attenuated inflammatory responses and shows therapeutic
135 h molecular weight HA reduces sensitization, attenuating inflammatory and neuropathic hyperalgesia.
136 ety and immunogenicity of an avian H5N2 live attenuated influenza vaccine (LAIV H5N2) in healthy Thai
137 andomized controlled trial [cRCT]) used live attenuated influenza vaccine, 11 (7 cRCTs) used inactiva
140 rictor and IRS-1 phosphorylation by p70S6K1 attenuate insulin action through a negative feedback pat
141 It enhances the secretion of insulin, but attenuates insulin's metabolic actions in the liver, ske
142 Finally, we determine that DOCK5 inhibition attenuates invasion and metastasis of MDA-MB-231 cells a
149 l adhesion molecule expression, resulting in attenuated leukocyte-endothelial interaction in vitro an
152 te (CH) and pea protein hydrolysate (PPH) by attenuating lipopolysaccharide- (LPS) induced pro-inflam
153 cal interference with IgA(+) cell generation attenuates liver carcinogenesis and induces cytotoxic T-
155 fering RNA targeting class II transactivator attenuates major histocompatibility complex class II exp
156 cells undergoing osteogenic differentiation attenuated matrix mineralization, cytoskeletal rearrange
157 t caspase-1 promotes TAMs differentiation by attenuating medium-chain acyl-CoA dehydrogenase activity
159 ; introducing mutations to disrupt either SL attenuated miR159 efficacy, while introducing complement
161 escent common mental disorders substantially attenuated most associations, with the exception of dail
164 V treatment markedly reduces SLN expression, attenuates muscle pathology and improves diaphragm, skel
165 P genes (N-P) of rHPIV1 bearing a stabilized attenuating mutation in the P/C gene (C(Delta170)).
166 c marker to screen for spontaneous virulence-attenuating mutations in L. monocytogenes Sixty nonhemol
169 TP1B deletion reduces axonal TrkA levels and attenuates neuron survival and target innervation under
172 model included geographic site, there was an attenuated nonsignificant association between racial com
173 reduction in apoB levels and a corresponding attenuated nonsignificant risk of major cardiovascular e
174 tion within the lungs were not significantly attenuated nor were a host of circulating or intra-alveo
175 that S1pr2 signalling posttranscriptionally attenuates Notch signalling levels, thus regulating line
176 s within a PMS2 C-terminal (721)QRLIAP motif attenuate or abolish human MutLalpha interaction with PC
177 whether activation of PZ(Vgat) neurons could attenuate or block the wake-promoting effects of two wid
179 intake and fat oxidation were significantly attenuated or absent when compared to those with increas
183 although PIN1 increases p27 levels, it also attenuates p27's inhibitory activity on CDK2 and thereby
185 er cobalt protoporphyrin IX more efficiently attenuated PGE2 and IL-6 release in HG+IL-1beta-treated
186 upports local resonances which create highly attenuating phononic bandgaps at frequencies with neglig
191 HIF-1alpha-dependent mechanisms, comprising attenuated pro-inflammatory activation of macrophages, i
196 development and preclinical evaluation of an attenuated recombinant human parainfluenza virus type 1
197 th the same reduction in LDL-C levels but an attenuated reduction in apoB levels and a corresponding
198 -1 knockdown also prevented ceftriaxone from attenuating reinstatement and from upregulating xCT expr
199 nd discusses matrix-based therapies that may attenuate remodeling while promoting repair and regenera
204 ssion in vitro and in vivo In conclusion, an attenuated rHPIV1 vector expressing a pre-F-stabilized f
205 P = .79 for difference), but a significantly attenuated risk of CHD per unit change in LDL-C level (O
207 cifically for osteogenesis, and concurrently attenuated Runx2 and Osx via BMP-mediated SMAD1/5 phosph
209 monstrated that TcpB protein can efficiently attenuate Salmonella enterica serovar Typhimurium-induce
210 .8 (95% confidence interval [CI] = 3.6-6.4), attenuated slightly to 3.9 (95% CI = 2.9-5.4) after adju
213 the efficacy of mucosal vaccination via this attenuated strain and will guide its further development
214 Inhalational MtbDeltasigH, a stress-response-attenuated strain, protected against lethal TB in macaqu
215 coprotein (G) gene, even in most recombinant attenuated strains, can still show substantial adverse o
216 tial approach of modulating Abeta levels and attenuating synaptic deficits in AD.SIGNIFICANCE STATEME
217 PORTANCE A chimeric yellow fever-dengue live-attenuated tetravalent vaccine is now being marketed.
218 etion, and the chances that one or more live attenuated tetravalent vaccines (LATVs) will be introduc
221 nhibitory effect of cocaine on DA uptake and attenuate the effects of SRI-compounds on cocaine-mediat
222 results indicate that proline-rich stretches attenuate the potential of stem cell active homeobox gen
223 ation from our motor commands to predict and attenuate the sensory consequences of our movements.
224 or (IGF-IR) is a new therapeutic strategy to attenuate the underlying autoimmune pathogenesis of opht
226 s with Ex-4 (25 to 100 nM), prior to injury, attenuated the cytotoxic effects of BSI and preserved ne
227 placebo treatment, treatment with estradiol attenuated the effects of ACE and TD such that no betwee
229 ith IL-17A receptor signaling in human PBMCs attenuated the expression of numerous inflammatory media
230 lls did not block an autophagy response, but attenuated the expression of several DNA double-strand b
234 data show that prefrontal infusions of KYNA attenuated the inhibitory component of PFC LFP responses
235 ty, slowed the in vitro sliding velocity and attenuated the inhibitory potential of the allosteric my
236 -beta mAb (1-10 mg/kg) but not the FnEDA mAb attenuated the injury-induced collagen deposition detect
239 protect the mice from obesity, but markedly attenuated the obesity-induced lipid accumulation in the
245 ted innate and adaptive immune responses and attenuated the upregulation of the TGF-beta signaling pa
246 -gamma, IL-1beta, IL-6, and CCL2 mRNAs), and attenuated the wasting syndrome and severity of colitis
247 Knockout of beta-arrestin-2 (betaarr-2(-/-)) attenuates the asthma phenotype as in beta2AR(-/-) mice.
248 inflammatory response stimulated by LPS and attenuates the inflammatory impact of a high fat diet on
250 At the level of cell-to-cell junctions, HGF attenuates the linkage of stress fibers to cell-to-cell
251 tein oxidation in FABP4/aP2(-/-) macrophages attenuates the mitochondrial unfolded-protein response (
252 , prevents corneal transplant rejection, and attenuates the progression and severity of autoimmune di
254 nction and the global decline in pollinators attenuates the resistance of natural areas and agro-envi
257 ylation, in turn, regulates transcription by attenuating the effect of local arginine methylation.
258 ntially explaining the synergistic effect of attenuating the expression of both HsRAD52 and BRCA2.
259 inding are much more challenging to develop; attenuating the number of false positives and false nega
261 early-life exposure, especially to cat, for attenuating the risk of childhood asthma, pneumonia, and
262 hase of voltage sensor stabilization without attenuating the slower phase, suggesting that the S4-S5
263 Further adjustment for body mass index (BMI) attenuated these associations but remained significant f
264 osed to HCV, and knockdown of TLR7 partially attenuated this expression, suggesting roles for TLR7/8
266 ty may provide novel therapeutic targets for attenuating this inflammation and thereby preventing CKD
269 d evidence for the first time that baicalein attenuated TNBS-induced colitis, at least in part, via i
270 ) in volume, whereas the X-ray beam is often attenuated to protect the detector from damage caused by
272 is characterized both with APXPS and in situ attenuated total reflectance Fourier transform infrared
274 thin the membrane skin layer determined from attenuated total reflection Fourier transform infrared s
275 n the mid-infrared region using conventional attenuated total reflection Fourier transform spectrosco
276 stigated PM-AMP electrostatic interaction by attenuated total reflection Fourier-transform infrared s
277 reveal a clear HS11 freshwater signal, which attenuated toward the eMed, and also that last interglac
278 erexpressing HOTAIR in TRAIL-sensitive cells attenuated TRAIL-induced apoptosis, and shRNA-mediated H
281 ration of basal-like TNBC cells in vitro and attenuates tumor growth in a mouse xenograft model.
282 idendritic nociceptive neuron, significantly attenuated ultraviolet injury-induced sensitization.
283 .79 x 10-6), but these associations were not attenuated upon adjustment for TIBC-so iron is not likel
285 Lipid metabolite oscillations were strongly attenuated upon siRNA-mediated clock disruption in human
287 tential strategy to develop a neurovirulence-attenuated vaccine against chickenpox and herpes zoster
288 pening the possibility for its use as a live-attenuated vaccine platform for ZIKV and other clinicall
289 o the development of safe and effective live attenuated vaccines directed against VEEV and perhaps ot
293 studies of NSs and potentially the design of attenuated viruses for vaccination studies.IMPORTANCE SF
294 accumulated in rodent eyes and optic nerves, attenuated visual dysfunction, and prevented retinal gan
295 e and glucose intolerance coexist and may be attenuated when drugs with NHE inhibitory actions are gi
296 ding the H3N2 NS1-D189N protein was slightly attenuated, whereas the virus encoding the H3N2 NS1-V194
298 han et al. show that a single dose of a live-attenuated Zika vaccine prevents infection, testis damag
300 ainst herpes zoster (HZ) induced by the live attenuated zoster vaccine Zostavax (ZVL) wanes within 3-
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