ライフサイエンスコーパス: aubergine

1 that guide post-transcriptional silencing by Aubergine.

2 izes and binds the sDMAs of the Piwi protein Aubergine.

3 pted in stocks heterozygous for mutations in aubergine, a gene whose protein product is involved in R

4 e to the perinuclear nuage and interact with Aubergine, a PIWI class protein.

5 nts profiled were tomato, pepper, chilli and aubergine, all members of the Solanaceae family.

6 to contain two of the three PIWI proteins - Aubergine and Argonaute 3 (AGO3) - that are essential fo

7 The Piwi-interacting RNA (piRNA) proteins Aubergine and Argonaute 3, known to suppress transposons

8 cells, PIWI-interacting RNAs (piRNAs) direct Aubergine and Argonaute3 to cleave transposon transcript

9 nds on two genes involved in RNAi phenomena, aubergine and spindle-E (spn-E), for its nuage localizat

10 Mutations in aubergine and spindle-E, members of the PIWI/PAZ and DE-

11 Instead, Piwi requires Aubergine (and presumably secondary piRNA) for proper lo

12 ree gonad-specific Argonaute proteins (Piwi, Aubergine, and Argonaute 3).

13 three Drosophila Piwi proteins--called Piwi, Aubergine, and Argonaute 3--Piwi is the only member of t

14 tion, the survival and viral titers of Piwi, Aubergine, Argonaute-3, and Zucchini mutant flies were s

15 Instead, fly Aubergine as well as its homologs, Siwi in silkmoth and

16 In Drosophila, two Piwi proteins, Aubergine (Aub) and Argonaute-3 (Ago3), localize to peri

17 all three PIWI proteins in Drosophila; Piwi, Aubergine (Aub) and Argonaute3 (Ago3) during early embry

18 RNA cleavage--catalyzed by the PIWI proteins Aubergine (Aub) and Argonaute3 (Ago3) in Drosophila mela

19 n association with Argonaute family proteins Aubergine (Aub) and Argonaute3 (AGO3).

20 dor domain protein Qin and the PIWI proteins Aubergine (Aub) and Argonaute3 (Ago3).

21 e now identified the Argonaute family member Aubergine (Aub) as a nos localization factor.

22 Piwi family protein Aubergine (Aub) maintains genome integrity in late germ

23 relies on three Piwi family proteins--Piwi, Aubergine (Aub), and Ago3--acting in concert with their

24 We also found that mutations in aubergine (aub), another gene implicated in the rasiRNA

25 especially those loaded on the Piwi protein Aubergine (Aub), are transmitted to the germ plasm to in

26 Aubergine (Aub), Argonaute 3 (Ago3), and components of t

27 domains, associates physically with Piwi and Aubergine (Aub), stabilizing these proteins via a gonad-

28 osophila Piwi protein and find that Piwi and Aubergine bind RNAs that are predominantly antisense to

29 While aubergine-dependence is conferred upon oskar mRNA by seq

30 rosophila rasiRNA pathway genes armitage and aubergine disrupt embryonic axis specification, triggeri

31 Aubergine glycans contain abundant heteroxylan epitopes,

32 Previously, aubergine has been implicated in dorsoventral patterning

33 We have isolated two new alleles of aubergine in a novel genetic screen and have shown that

34 Nature, Vourekas et al. (2016) suggest that Aubergine in complex with piRNAs may provide a low-speci

35 In this report, we describe the role of aubergine in oskar translation.

36 n a novel genetic screen and have shown that aubergine is also required for posterior body patterning

37 stent with its presence in these structures, Aubergine is required for pole cell formation independen

38 Thus, aubergine is required to enhance oskar translation.

39 oskar mRNA by sequences in the oskar 3' UTR, aubergine may influence oskar translation through an int

40 tterning, as the small fraction of eggs from aubergine- mothers that are fertilized develop into embr

41 ted in dorsoventral patterning, as eggs from aubergine mutant mothers are ventralized and seldom fert

42 aubergine mutants fail to translate oskar mRNA efficient

43 of oskar protein is significantly reduced in aubergine mutants.

44 Although aubergine mutations do not appear to affect the stabilit

45 aubergine mutations exert their effects in the female ge

46 n loop in which an antisense piRNA, bound to Aubergine or Piwi protein, triggers production of a sens

47 silencing as a result of mutations in piwi, aubergine, or spindle-E (homeless), which encode RNAi co

48 We have found that Aubergine protein is related to eukaryotic translation i

49 wn polar granule components, Vasa and Oskar, Aubergine remains cytoplasmic after pole cell formation,

50 d that the Tudor domain protein Qin prevents Aubergine's cleavage products from becoming Piwi-bound p

51 Lines derived from mutant aubergine stocks reestablish the P cytotype quickly, unl

52 parenchyma tissues of four fruits - tomato, aubergine, strawberry and apple - we have dissected cell

53 Drosophila piRNAs bound to the PIWI protein Aubergine typically begin with uridine (1U), while piRNA

54 In addition, we found that Aubergine was recruited to the posterior pole in a vas-d