ライフサイエンスコーパス: audiogenic

1 s in an enhanced seizure-like response to an audiogenic challenge.

2 nels) and for anticonvulsant activity in the audiogenic DBA/2 mouse model.

3 the IMR32 assay) and was efficacious in the audiogenic DBA/2 seizure mouse model (ED(50) = 6 mg/kg,

4 t anticonvulsant activity in rodents against audiogenic, electrically induced, and chemically induced

5 t anticonvulsant activity in rodents against audiogenic, electrically induced, and chemically induced

6 G dysregulation is a cause or consequence of audiogenic epilepsy and whether there are other pathways

7 ected death in epilepsy (SUDEP) that exhibit audiogenic generalized convulsive seizures (GCS), ending

8 tition of audiogenic seizures (AGS) leads to audiogenic 'kindling' with increased seizure duration an

9 s 5, ahl5) and audiogenic seizures (juvenile audiogenic monogenic seizure 1, jams1) in mice and autos

10 e previously identified a locus for juvenile audiogenic monogenic seizures (jams1) in the Black Swiss

11 e localize the seizure gene, jams1 (juvenile audiogenic monogenic seizures), to a 1.6 +/- 0.5 centimo

12 ts ability to protect against seizures in an audiogenic mouse animal model of epilepsy.

13 i-induced generalized tonic-clonic seizures (audiogenic reflex seizures) and is a valid model to stud

14 eurons specifically in the AC, and displayed audiogenic reflex seizures.

15 Frequent repetition of audiogenic seizure (AGS) ('AGS kindling') in the severe

16 initiation site in the neuronal network for audiogenic seizure (AGS) in rats undergoing ethanol with

17 (IC) central nucleus (ICc), is critical for audiogenic seizure (AGS) initiation in the genetically e

18 3ahl variant may account for the hearing and audiogenic seizure differences observed between Frings a

19 The rats were tested for audiogenic seizure intensity at 0.25, 1, 2, 3, and 4 h a

20 activity in the DBA/2 strain of mouse in an audiogenic seizure model.

21 human 14q11.2-q13, which contains the asp1 (audiogenic seizure prone) locus in the mouse.

22 trols and a group of animals displaying high audiogenic seizure susceptibility (100% AGS) (HAGS), and

23 e human ortholog of the gene responsible for audiogenic seizure susceptibility in Frings and BUB/BnJ

24 ve GSK3 promotes locomotor hyperactivity and audiogenic seizure susceptibility in FX mice, raising th

25 RK1/2 pathway activation also contributes to audiogenic seizure susceptibility in the Fmr1 KO.

26 al audiogenic startle response and increased audiogenic seizure susceptibility.

27 receptor 1), also known as MASS1 (monogenic audiogenic seizure susceptible 1), is an orphan G protei

28 rings strain, 391 of the 836 N2 progeny were audiogenic seizure susceptible, a finding consistent wit

29 the seizure gene, named mass1 for monogenic audiogenic seizure susceptible, to an approximately 3.6

30 mg/kg had no effect in 4/4 rats made acutely audiogenic seizure-prone by infusion of bicuculline into

31 entricular (i.c.v.) administration of GRP to audiogenic seizure-prone DBA/2 mice prior to exposure to

32 cortical wedges prepared from 20-30 day-old, audiogenic seizure-prone DBA/2 mice.

33 nt sound-triggered seizures in post-ischemic audiogenic seizure-prone rats.

34 Frings audiogenic seizure-susceptible mice are a model for sens

35 produced no reduction in the severity of the audiogenic seizure.

36 During ETX in rodents, generalized audiogenic seizures (AGS) can be triggered by intense ac

37 implicated in the neuronal network for these audiogenic seizures (AGS) in animals undergoing ETX.

38 pathway is also implicated in the network of audiogenic seizures (AGS) in genetically epilepsy-prone

39 Studies of audiogenic seizures (AGS) in genetically epilepsy-prone

40 iculus (DLSC) play a role in the network for audiogenic seizures (AGS) in genetically epilepsy-prone

41 us studies indicate that daily repetition of audiogenic seizures (AGS) leads to audiogenic 'kindling'

42 In rodents, ETX results in susceptibility to audiogenic seizures (AGS), and the DLSC are implicated a

43 t-ictal analgesia occurs in GEPRs, following audiogenic seizures (AGS), and whether this analgesia in

44 (GEPR-3s) exhibits generalized onset clonic audiogenic seizures (AGS), but following repetitive AGS

45 ucture in the requisite neuronal network for audiogenic seizures (AGS), which is confined to the brai

46 f generalized convulsive seizures, including audiogenic seizures (AGS).

47 ) are implicated in the neuronal network for audiogenic seizures (AGS).

48 ethanol withdrawal (ETX) syndrome, including audiogenic seizures (AGS).

49 LSC) play a role in the neuronal network for audiogenic seizures (AGS).

50 loss (age-related hearing loss 5, ahl5) and audiogenic seizures (juvenile audiogenic monogenic seizu

51 controls to flurothyl, PTZ, kainic acid, and audiogenic seizures and enhanced sensitivity (i.e., seiz

52 tigation studied the mode of inheritance for audiogenic seizures by crossing the Frings mouse with th

53 luated the sensitivity of this mouse line to audiogenic seizures early in the disease course.

54 We therefore reason that juvenile audiogenic seizures in Black Swiss mice are unlikely to

55 normalize protein synthesis and also reduce audiogenic seizures in Fmr1 knockout mice.

56 , an RSK inhibitor reduces susceptibility to audiogenic seizures in fragile X mice.

57 ice all exhibit an enhanced tendency to have audiogenic seizures in response to white noise stimuli a

58 a significant decrease in the percentage of audiogenic seizures in the Fmr1KO animals.

59 scribe a mutation in a novel gene underlying audiogenic seizures in the Frings mouse, providing a val

60 Single episode of reflex audiogenic seizures in the GEPR-3s did not significantly

61 Cloning the gene for audiogenic seizures in these mice may provide important

62 ological dysfunction, neurodegeneration, and audiogenic seizures that manifest beginning in early adu

63 eurological applications, such as preventing audiogenic seizures that originate in the auditory midbr

64 ependent LTD, neocortical hyperexcitability, audiogenic seizures, and altered behaviors, including an

65 mice exhibited impaired motor coordination, audiogenic seizures, and brainstem neurodegeneration.

66 re susceptible to sound-induced convulsions (audiogenic seizures, or AGSs).

67 acoustic hypersensitivity and propensity for audiogenic seizures, suggesting altered auditory respons

68 rotein synthesis, exaggerated mGluR-LTD, and audiogenic seizures.

69 areas for the initiation and propagation of audiogenic seizures.

70 relate with susceptibility and resistance to audiogenic seizures.

71 that is critical in the initiation of reflex audiogenic seizures.

72 der, including sudden unexplained deaths and audiogenic seizures.

73 behaviour, defective social interaction and audiogenic seizures.

74 fore unrecognized specific susceptibility to audiogenic seizures.

75 fmr-1 knockout (KO) mice evident as abnormal audiogenic startle response and increased audiogenic sei

76 ice (effective dose [ED]50 = 79.7 mg/kg) and audiogenic stimulation in Fring's mice (ED50 = 206.4 mg/

77 seizures evoked by 6 Hz stimulation in mice, audiogenic stimulation in Fring's mice, and maximal elec

78 wal and convulsions elicited by chemical and audiogenic stimuli.

79 seizure response to pentylenetetrazol or an audiogenic stimulus.

80 us involved in activation of the HPA axis by audiogenic stress are discussed.

81 ary-adrenocortical (HPA) axis in response to audiogenic stress in rats.

82 We have determined previously that audiogenic stress is associated with a specific regional

83 Audiogenic stress is known to activate the hypothalamo-p

84 blockade of c-fos mRNA induction in several audiogenic stress responsive regions, also known to dire

85 s receiving FG in the PAmp were subjected to audiogenic stress, and the distribution of both FG and t

86 Together with prior findings with audiogenic stress, the present results suggest that eith

87 icker glucocorticoid habituation to repeated audiogenic stress.

88 might mediate activation of the HPA axis by audiogenic stress.

89 are critically involved in HPA activation by audiogenic stress.

90 ical HPA activational circuit in response to audiogenic stress.

91 tigated the ensuing effects of 2-h variable "audiogenic" stress on three related levels of hippocampa