ライフサイエンスコーパス: auditory hair cell

1 exocytosis of synaptic vesicles at the mouse auditory hair cell.

2 ganization and maintenance of stereocilia in auditory hair cells.

3 he growth and maintenance of hair bundles in auditory hair cells.

4 predominant influence on frequency tuning in auditory hair cells.

5 lls, and is no longer expressed in postnatal auditory hair cells.

6 fferent roles in terminal differentiation of auditory hair cells.

7 nt is a hallmark of functional maturation in auditory hair cells.

8 is shorter than normal with about 60% fewer auditory hair cells.

9 quency tuning in nonmammalian vestibular and auditory hair cells.

10 frequently branched to contact both types of auditory hair cells.

11 membrane compartments such as stereocilia of auditory hair cells.

12 by destruction and regeneration of inner ear auditory hair cells.

13 isms for controlling hair bundle position in auditory hair cells.

14 ctors that are essential for the function of auditory hair cells.

15 in the afferent neural projections to gerbil auditory hair cells.

16 timulus amplification during transduction in auditory hair cells.

17 hanoelectrical transducer currents in turtle auditory hair cells adapt to maintained stimuli via a Ca

18 Loss of auditory hair cells (AHCs) is a major cause of human dea

19 severely shortened with a reduced number of auditory hair cells and cellular organization of the aud

20 ce of mechanosensory function in postmitotic auditory hair cells and could help identify elusive comp

21 ns in Ptprq cause the loss of high-frequency auditory hair cells and deafness in mice, a loss of vest

22 ons are forming their final connections with auditory hair cells and nerve fibers, can lead to profou

23 However, protection of auditory hair cells and neurons from CDDP-induced damage

24 ng noise-induced peroxisome proliferation in auditory hair cells and neurons.

25 itors under these conditions was examined in auditory hair cells and neurons.

26 rotein that is essential for the survival of auditory hair cells and normal hearing in mice, possibly

27 A loss of cilia also occurs in auditory hair cells and olfactory sensory neurons.

28 llular structure that comprises two types of auditory hair cells and several types of nonsensory supp

29 lia bundle and affects long-term function of auditory hair cells and spiral ganglion neurons.

30 Auditory hair cells and supporting cells arise in a wave

31 sins are critical for the normal function of auditory hair cells and the function and maintenance of

32 The V-shaped hair bundles atop auditory hair cells and their uniform orientation are ma

33 NF-M was detected in auditory hair cells and VIIIth cranial nerve neurons.

34 minently located in lateral-line hair cells, auditory hair cells, and ciliated epidermal cells of dev

35 owing that chordotonal organs and vertebrate auditory hair cells are developmentally related and that

36 Stereocilia maintenance is essential because auditory hair cells are not renewed in mammals.

37 Auditory hair cells are surrounded on their basolateral

38 In adult mammals, auditory hair cells are unable to regenerate, and damage

39 Sound stimuli vibrate the hair bundles on auditory hair cells, but the resulting motion attributab

40 The cell membranes in the hair bundle of an auditory hair cell confront a difficult task as the bund

41 Auditory hair cells contain mechanotransduction channels

42 Turtle auditory hair cells contain multiple isoforms of the por

43 We report here that auditory hair cells contain two molecularly distinct mec

44 Auditory hair cell defect is a major cause of hearing im

45 g hair bundle, the mechanosensory antenna of auditory hair cells, depends on the poorly characterized

46 We report that in contrast to matured auditory hair cells, depletion of membrane cholesterol i

47 e deaf and exhibit no mechanotransduction in auditory hair cells, despite the presence of tip links t

48 In the absence of Dll1, auditory hair cells develop early and in excess, in agre

49 Auditory hair cells developed normally in Pls1 KO, but i

50 vered alterations in cochlear morphogenesis, auditory hair cell differentiation, and cell fate specif

51 Mammalian auditory hair cells do not spontaneously regenerate, unl

52 In contrast, regeneration of lost auditory hair cells does not occur in deafened mammals,

53 mechanotransducer currents in turtle and rat auditory hair cells during rapid deflections of the hair

54 edback available to a bird by killing either auditory hair cells encoding higher frequencies or those

55 rganization, F-actin-enriched stereocilia of auditory hair cells evidenced structural disorganization

56 To this end, turtle auditory hair cells from high- (317 +/- 27 Hz) and low-f

57 Auditory hair cells from nonmammalian vertebrates are el

58 a nonsensory structure that is essential for auditory hair cell function by maintaining potassium con

59 Auditory hair cell function requires proper assembly and

60 During transduction in auditory hair cells, hair bundle deflection opens mechan

61 ice, abnormally short stereocilia bundles of auditory hair cells have numerous stereocilia links and

62 Unlike mammals, birds regenerate auditory hair cells (HCs) after injury.

63 Adult mammalian auditory hair cells (HCs) and their associated supportin

64 Mammalian auditory hair cells (HCs) are inserted into a well struc

65 P(2) pool in the cell syncytia that supports auditory hair cells; (ii) spatially graded impairment of

66 ells in the cochlea, and the regeneration of auditory hair cells in adult mammals.

67 The frequency sensitivity of auditory hair cells in the inner ear varies with their l

68 rmanent moderate deafness due to the loss of auditory hair cells in the inner ear.

69 n the cristae of the semicircular canals and auditory hair cells in the organ of Corti.

70 The distinctive planar polarity of auditory hair cells is evident in the polarized organiza

71 gs show that MET current adaptation in mouse auditory hair cells is modulated similarly by extracellu

72 Hearing loss due to damage to auditory hair cells is normally irreversible because mam

73 ggests that regeneration/repair of mammalian auditory hair cells is possible during the early neonata

74 ive microvilli-like stereocilia crowning the auditory hair cells, is essential to hearing.

75 th muscle relaxation and frequency tuning of auditory hair cells, large-conductance calcium-activated

76 th calcium imaging of hair bundles in turtle auditory hair cells located near the high-frequency end

77 Auditory hair cells of birds, unlike hair cells in the m

78 Auditory hair cells of shaker-2 mice have very short ste

79 compared the mechanotransduction current in auditory hair cells of young normal-hearing littermates,

80 In the auditory hair cells of young postnatal mice and rats, a

81 Auditory hair cells preferentially express Fzd2 and Fzd9

82 ral, spatial, and morphologic progression of auditory hair cell regeneration in chicks after a single

83 rds; the chick is the best-studied model for auditory hair cell regeneration.

84 Auditory hair cells represent one of the most prominent

85 The auditory hair cell resting potential is critical for pro

86 nce, can explain the seasonal enhancement of auditory hair cell sensitivity to the frequency content

87 hat paired-pulse plasticity at an adult frog auditory hair cell synapse depends on pulse duration and

88 iate glutamatergic transmission at the adult auditory hair cell synapse.

89 We found that mouse auditory hair cells that lack tip links due to genetic m

90 ver, nonmammalian vertebrates can regenerate auditory hair cells that restore sensory function.

91 Direct comparisons between neighboring auditory hair cells that were different only with respec

92 In turtle auditory hair cells, the filtering properties are establ

93 In terminally differentiated mammalian auditory hair cells, tip links are subjected to sound-in

94 -scaffold protein involved in vestibular and auditory hair cell transduction, is also expressed by pr

95 The loss of auditory hair cells triggers repair responses within the

96 we measured hair bundle compliance in turtle auditory hair cells under different conditions that alte

97 These observations demonstrate that auditory hair cells undergo a rapid and controlled proce

98 Using rat auditory hair cells, we characterize a mechanism, separa

99 ucleus and the supporting cells of the outer auditory hair cells were named, died in 1863 aged 29.

100 rt evidence for proton release from bullfrog auditory hair cells when they are held at more physiolog

101 mechanistic model for vesicle exocytosis in auditory hair cells where the rate of vesicle recruitmen

102 Hearing requires proper function of the auditory hair cell, which is critically dependent upon i