ライフサイエンスコーパス: autoactivate

1 ion of kallikrein; factor XII alone does not autoactivate.

2 he propeptide domain controls its ability to autoactivate.

3 ata show that tethered PTH/PTH receptors can autoactivate.

4 ically inactive soluble hepsin was unable to autoactivate.

5 expressed in Escherichia coli, purified, and autoactivated.

6 alyses demonstrated that the cpxRA operon is autoactivated.

7 , except that constitutively active ARF6 was autoactivating.

8 The ability to autoactivate and then subsequently repress allows for a

9 lysosomal environment because the zymogen is autoactivated and remains optimally active in acidic con

10 C1r both autoactivates and subsequently cleaves and activates C1s

11 cognition protein that binds to bacteria and autoactivates and triggers the prophenoloxidase activati

12 sor (pro-HP14) interacts with peptidoglycan, autoactivates, and initiates the proteinase cascade.

13 lytic cleavage of both the transducer, which autoactivates, and the repressor, which is inactivated,

14 The K162M mutant did not autoactivate as predicted, however, which may be due to

15 tivation, whereas the Asp(22) --> Ala mutant autoactivated at a 66-fold increased rate.

16 ere identical; however, at pH 5.0, Ile-21-Tg autoactivated at an enhanced rate relative to Asn-21-Tg.

17 eatitis (N29I, N29T, V39A, R122C, and R122H) autoactivated at increased rates and reached markedly hi

18 Many protein kinases autoactivate by autophosphorylating specific sites at th

19 e marRAB operon is autorepressed by MarR and autoactivated by MarA at a site that also can be activat

20 tron 1 that is activated by activin and Vg1, autoactivated by Xnrs, and suppressed by ventral inducer

21 o p38alpha, is exceptional and spontaneously autoactivates by autophosphorylation.

22 Factor XII (FXII) autoactivates by contact with a variety of artificial or

23 The Ct beta(2) protein also autoactivates by reaction of its reduced (Mn(II)/Fe(II))

24 Intracellular infusion of autoactivated CaMKII via patch pipette enhanced chloride

25 activates the glnA promoter, this creates an autoactivated circuit repressible by LacI.

26 The caspase autoactivating compound PAC-1 induces cancer cell apopto

27 mammalian development, making its ability to autoactivate critical to its function.

28 (rho), and that sog functions by blocking an autoactivating Dpp feedback loop.

29 tion of apoptosis and differentiation by the autoactivating enediyne, enediyne-5, and the non-enediyn

30 ry glands of transgenic mice that express an autoactivating form of MMP-3/stromelysin-1 under the con

31 Expression of an autoactivating form of MMP-9 in macrophages in vitro gre

32 An allele-specific interaction between an autoactivating form of Snake (Snk) and a gd allele alter

33 Unexpectedly, at a systems level, autoactivated Fus3 appears to have a negative regulatory

34 Addition of autoactivated HP14 elevated phenoloxidase activity level

35 al control over the production of snc1-1 (an autoactivated immune receptor) in Arabidopsis thaliana a

36 luble form of hepsin revealed its ability to autoactivate in a concentration-dependent manner.

37 ssistance of another protease and is able to autoactivate in acidic pH in vitro via a unimolecular me

38 Nercc1 exists as a homooligomer and can autoactivate in vitro by autophosphorylation.

39 Herein we show that purified BACE2 can be autoactivated in vitro.

40 sexta: hemolymph proteinase 14 (HP14), which autoactivates in the presence of microbial surface compo

41 The Nercc1 protein kinase autoactivates in vitro and is activated in vivo during m

42 nzymatically dephosphorylated purified Rad53 autoactivates in vitro through a phosphorylation-depende

43 omain propagates the death signal through an autoactivating interaction with the trigger site of inac

44 a-secretase or is itself gamma-secretase, an autoactivated intramembranous aspartyl protease.

45 MASP-3, which does not autoactivate, is also cleaved by MASP-1 quite efficientl

46 In primary T cells, c-Myb allows GATA-3 to autoactivate its own expression, an event that requires

47 Here, we report that BMI1 autoactivates its own promoter via an E-box present in i

48 ranscriptional fusion, we observed that QseB autoactivates its own transcription.

49 ory zinc ions, thus allowing procaspase-3 to autoactivate itself to caspase-3.

50 This shows that autoactivating kinases have adopted different molecular

51 that prostate carcinoma cells LNCaP and PC3 autoactivate latent full-length PDGF D into its active f

52 Until now the autoactivating mannose-binding lectin-associated serine

53 We previously showed that targeting of an autoactivating mutant of the matrix metalloproteinase st

54 mulate expression of endogenous ORF50 and to autoactivate ORF50 promoter reporters.

55 nd GadX activate P3, P2 and P3P2, while GadE autoactivates P1 and represses P3 and P3P2.

56 other Gram-positive bacteria, agr encodes an autoactivating peptide (AIP) that is the inducing ligand

57 alleles under both constitutive (PrpsL) and autoactivated (Pmga4) promoters illustrated that an argi

58 cancer cells, where it displayed an enhanced autoactivating process and a distinct intracellular rout

59 These data suggest that matriptase, an autoactivating protease, acts upstream from prostasin to

60 Using this system, we defined an autoactivating role for Etv2 that is mediated by two adj

61 ionally normal cells expressing an inducible autoactivating stromelysin-1 (SL-1) transgene.

62 1 transgenic animals with mice expressing an autoactivating stromelysin-1 transgene targeted to mamma

63 alveolar epithelial cells of mice expressing autoactivating stromelysin-1 underwent unscheduled apopt

64 We determined the crystal structure of autoactivated ThnT to 1.8A through X-ray crystallography

65 relief of this inhibition, SnRK2 kinases can autoactivate through unknown mechanisms.

66 ndicated that this receptor was sufficiently autoactivated to produce at least partial differentiatio

67 The yeast Candida glabrata rapidly autoactivates transcription of the AMT1 gene in response

68 We show that, although MASP-2 is able to autoactivate under artificial conditions, MASP-1 dramati

69 Its proenzyme autoactivates under acidic conditions in vitro, resultin

70 activation by upstream kinases, p38alpha can autoactivate when interacting with transforming growth f

71 ses, MASP-1 and MASP-2, have been thought to autoactivate when MBL/ficolin.MASP complexes bind to pat

72 proDelta(260-508)MMP-19 has the tendency to autoactivate, whereby the Lys(97)-Tyr(98) peptide bond i