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1 luster edges, implying tetramer formation is autocatalytic.
2 ee energy barrier of 36.1 kcal/mol and to be autocatalytic.
3 and the specific ribosome synthesis rate is autocatalytic.
4 ndicating that the covalent flavinylation is autocatalytic.
5 nts of axon/dendrite formation involve local autocatalytic activation and long-range inhibition, as p
6 cells to generate metabolic oscillations via autocatalytic activation by its product fructose 1,6-bis
7 he PC7 precursor protein undergoes efficient autocatalytic activation in both oocytes and embryos.
12 1 is approximately 3000-fold higher, and the autocatalytic activation of MASP-1 is about 140-fold fas
15 signal of bioanalytical assays based on the autocatalytic activation of these mutated proenzymes.
17 enzyme molecule of the same protease, and 2) autocatalytic activation, when the activated protease cl
19 as an excitable system in which a diffusive, autocatalytic activator causes actin polymerization; F-a
21 onstitutively active enzyme, with high basal autocatalytic activity and high basal activity toward pe
22 atalytic domain) display high basal Ser(916) autocatalytic activity and robust activity toward CREBti
23 tion requires ATG7 as the E1 enzyme and ATG3 autocatalytic activity as the E2, resulting in the coval
24 of ADAMTS17 requires O-fucosylation and its autocatalytic activity does not depend on propeptide pro
25 available for several classes of enzymes and autocatalytic activity encoded by nonenveloped viruses.
29 he inflammasome results in initiation of its autocatalytic activity, culminating in self-cleavage tha
31 ty paradigm, which appears to be general for autocatalytic additions to heme prosthetic groups, sugge
32 lar particle agglomeration, B + B --> C, and autocatalytic agglomeration, B + C --> 1.5C, involved in
35 s likely to contain a subsystem that is both autocatalytic and able to survive on some ambient 'food'
36 self-assembles into nanostructures, coupling autocatalytic and assembly pathways to realize a reprodu
38 However, those reactions with aniline were autocatalytic and had significant induction periods ( ap
40 ities of the two-segment compound enable the autocatalytic, and in general ROS-mediated, activation o
42 nd serve as mother filaments to initiate the autocatalytic assembly of the branched actin filament ne
43 e; however, it remains to be seen whether an autocatalytic-based drug delivery system has an advantag
44 ysts have been previously reported, coupling autocatalytic behavior to macromolecular self-assembly h
45 branches are generated by existing branches (autocatalytic behavior) or independently of existing bra
48 sible chemical and physical stimuli, and the autocatalytic behaviours within DCLs which can result in
49 to build a network of organic reactions with autocatalytic, bistable and oscillatory behaviour, we id
51 nmol/min for 2 min or more, which sets up an autocatalytic cascade triggered by activating type 2 nit
55 en involves large conformational changes and autocatalytic chemistry that can be hampered by small mo
56 ses with single-stranded RNA genomes undergo autocatalytic cleavage (autocleavage) as a maturation st
58 ondrial processing peptidase and Oct1 and an autocatalytic cleavage at a highly conserved LGST motif
61 sitol-linked protein and undergoes a partial autocatalytic cleavage during its intracellular processi
62 in GPCR proteolytic site motifs that undergo autocatalytic cleavage during receptor processing to cre
66 s serine proteinase activity and can undergo autocatalytic cleavage liberating distinct fragments.
67 wn protein fold and a functionally important autocatalytic cleavage mechanism and provides a framewor
68 tivation of the AIM2 inflammasome results in autocatalytic cleavage of caspase-1, resulting in the pr
70 inositol hexakisphosphate (InsP6) induces an autocatalytic cleavage of the toxins, releasing an N-ter
71 lowered from 7.6 to 5, and this activates an autocatalytic cleavage of the viral subunit at residue 5
72 dimension between pH 5.5 and 5 requires the autocatalytic cleavage to achieve its final compact size
73 tide precursor that undergoes intramolecular autocatalytic cleavage to generate a fully active hetero
76 e 226 on delta-secretase and accelerates its autocatalytic cleavage, leading to its cytoplasmic trans
77 ssion disrupts prohormone convertase 2 (PC2) autocatalytic cleavage, processing of secretogranin II t
79 dgehog (hh) encodes a protein that undergoes autocatalytic cleavage, releasing a signaling molecule i
81 ngle polypeptide (propeptide) that undergoes autocatalytic cleavage, which results in the formation o
86 rification of the pyromellitate system under autocatalytic conditions; minor ester exchange with pre-
87 ally altered host protein that multiplies by autocatalytic conversion has gained wide acceptance.
89 the role of the pro domain, we monitored the autocatalytic conversion of BACE1 by heteronuclear NMR s
91 ain and the entire pro domain, and undergoes autocatalytic conversion to yield the well-folded mature
98 ovided by supramolecular ordering enables an autocatalytic cycle favouring the growth of DNA chains,
100 tween three subcomponents of the network: an autocatalytic cycle that generates thiols and amides fro
101 hypercycle defines the simplest model of an autocatalytic cycle, providing major theoretical insight
105 tworks are competed directly against selfish autocatalytic cycles, the former grow faster, indicating
107 echanism whereby interphase cells can oppose autocatalytic cyclin E degradation and maintain cyclin E
110 ncomplete glycosylation stimulates extensive autocatalytic degradation and self-inactivation of MT1-M
111 e results we propose that TIR1 is subject to autocatalytic degradation when assembled into an SCF.
112 cantly increased (10-20-fold) propensity for autocatalytic degradation, relative to cationic trypsino
114 RING ubiquitin ligases (CRL) by limiting the autocatalytic destruction of substrate adapters such as
116 : catalytic formation of branched junctions, autocatalytic duplex formation by a cross-catalytic circ
119 er mild conditions by using the output of an autocatalytic enzyme reaction to drive both the polymeri
121 itself out of a precursor polypeptide in an autocatalytic fashion with concomitant linkage of the tw
124 d RFP (cpRFP) scaffold, which maintained its autocatalytic fluorescence, from a red fluorescent Ca(2+
127 d carboxyl group is the sole requirement for autocatalytic formation of a heme-protein link in P450 e
128 ormation and provide a working model for the autocatalytic formation of protocells from the coupling
130 ht chain of botulinum A neurotoxin undergoes autocatalytic fragmentation that is accelerated by the p
131 , when >95% of the light chain had undergone autocatalytic fragmentation, the preparation retained 35
132 (2)), and hydrogen peroxide (H(2)O(2)) in an autocatalytic free radical chain reaction, which could p
133 it is often claimed that self-sustaining or autocatalytic front propagation is well described by mea
138 eation (A --> B, rate constant k 1) and fast autocatalytic growth (A + B --> 2B, rate constant k 2),
139 r nucleation (A --> B, rate constant k1) and autocatalytic growth (A + B --> 2B, rate constant k2), w
140 meration (B + B --> C) and secondary surface autocatalytic growth (A + C --> 1.5C) involved in suppor
141 The use of the F-W 2-step nucleation and autocatalytic growth kinetic model to fit 3 literature e
142 een used to infer the presence or absence of autocatalytic growth processes such as fibril fragmentat
146 dialkyl disulfides; a trigger that controls autocatalytic growth; and inhibitory processes that remo
147 tween the T7 RNA polymerase promoter and the autocatalytic hepatitis delta virus ribozyme of a transc
148 ns between phenomena generally attributed to autocatalytic hydrolysis and mass transfer limitation ef
149 om chains grow more informational and become autocatalytic (i.e., increasing their own concentrations
152 edox cycle, unprecedented among LOX in being autocatalytic, in which the hydroperoxy substrate is iso
154 a glycosyltransferase that functions as the autocatalytic initiator for the synthesis of glycogen in
156 ht differentiates this protein splicing from autocatalytic inteins, and may allow the chloroplast to
158 s that the GPS proteolysis is mediated by an autocatalytic intramolecular reaction similar to that em
160 unds act as acid amplifiers and decompose by autocatalytic kinetics to generate fluorinated sulfonic
161 honetria parasitica, encodes two papain-like autocatalytic leader proteases, p29 and p48, that also h
162 OH(cat.)/AcCl system was found to promote an autocatalytic-like condensation and facilitate the multi
163 h ordering and condensation would provide an autocatalytic link whereby complementarity promotes the
166 ectivity of flock house virus (FHV) requires autocatalytic maturation cleavage of the capsid protein
167 ion (TFR)-PR-FLAG, also undergoes N-terminal autocatalytic maturation when it is expressed in Escheri
168 at Dia2 protein turnover does not involve an autocatalytic mechanism and that Dia2 proteolysis is inh
170 ivation of its E3 ligase activity through an autocatalytic mechanism that amplifies its E3 ligase act
171 stem reveals a new, enzyme-free, isothermal, autocatalytic mechanism that introduces means for effect
176 PR/Cas9 genome-editing system for generating autocatalytic mutations, to produce homozygous loss-of-f
177 oduces a molten silica shell that acts as an autocatalytic 'nanoreactor' by actively transporting oxy
178 ar, our results show that the characteristic autocatalytic nature of the growth process originates fr
182 f short, unstable microtubules maintained by autocatalytic nucleation and provide a paradigm for the
183 e rate at the adjacent two amides, often the autocatalytic nucleophiles in deamidation, correlated wi
187 Here, we demonstrate an interaction between autocatalytic PCD and lytic viral infection in the cosmo
188 ecombinant protein allowed monitoring of the autocatalytic peroxide-driven formation of covalent heme
189 ormation of the enzyme and indicative of PKC autocatalytic phosphorylation and activation during bact
190 e targets for a protein kinase C-independent autocatalytic phosphorylation and that the PKD1-S744A/S7
196 mbinant PrP displays specific features of an autocatalytic process and mimics the transmission barrie
200 uantitative understanding and control of the autocatalytic process involved in the synthesis of collo
202 vo from purified native PrPC molecules in an autocatalytic process requiring accessory polyanions.
203 endogenous ROS production in a regenerative, autocatalytic process that ultimately results in global
204 dal metal nanocrystals typically involves an autocatalytic process, in which the salt precursor adsor
210 Theoretical models have long suggested that autocatalytic processes can result in kinetically contro
212 the 44-kDa form of MT1-MMP generated during autocatalytic processing in maintaining the pool of acti
216 activation of SKI-1/S1P involves sequential autocatalytic processing of its N-terminal prodomain at
217 arked retardation of the in vitro N-terminal autocatalytic processing of TFR-PR(H69E) and suggesting
218 e dispensable for hypovirus replication, the autocatalytic processing of the leader proteases p29 and
219 ble from fully glycosylated TPP1 in terms of autocatalytic processing of the proform and enzymatic pr
220 icated that the p.G178R mutation impairs the autocatalytic processing of this enzyme resulting in the
222 ivity is revealed by maturation following an autocatalytic processing resulting in the cleavage of bo
223 ome catalytically active, Psd1p undergoes an autocatalytic processing step involving a conserved LGST
224 n the cell surface, active MT1-MMP undergoes autocatalytic processing to a major membrane-tethered 44
225 60-kDa inactive precursor that must undergo autocatalytic processing to generate a 40-kDa/20-kDa het
227 of the coupling between the enzyme-catalyzed autocatalytic production and diffusion of hydrogen ions.
228 pagation saturates, leading to a switch from autocatalytic production of infectivity (phase 1) to a t
230 whereas monomeric alpha-synuclein blocks the autocatalytic proliferation of Abeta42 (the 42-residue f
234 inducible signals that might accelerate its autocatalytic properties and dictate where inflammasome
239 ith oxyhemoglobin, and although this complex autocatalytic reaction has been studied for a century, t
242 outcome of both biological and nonbiological autocatalytic reaction systems that display a threshold
243 of apoMSOX has been shown to proceed via an autocatalytic reaction that requires only FAD and is blo
245 mutants by active alpha-thrombin triggers an autocatalytic reaction which leads to more active thromb
247 pective offers a rationalization of the Soai autocatalytic reaction; accounting for enantiomeric exce
249 r restricted the diffusion of copper and the autocatalytic reduction limited the probability for seco
251 y a nucleation-and-growth scenario involving autocatalytic reduction of the copper phyllosilicate fol
252 uniform size of precursor particles and the autocatalytic reduction thus offers means to synthesize
254 commitment requires efficient activation and autocatalytic release of caspase-8 into the cytoplasm to
255 C terminus is followed by an intramolecular autocatalytic removal of a 12-amino acid propeptide at t
256 ms of ADAM19 was first demonstrated by their autocatalytic removal of a purification tag (Myc-His) an
258 plification (PMCA) technology to sustain the autocatalytic replication of infectious prions in vitro.
262 trons remove themselves by protein-assisted, autocatalytic RNA splicing, thereby minimizing host dama
264 2) is a modifier in catalysis and acts in an autocatalytic role; there is a parallel, neutral catalys
265 nner mitochondrial membrane, must undergo an autocatalytic self-processing event to gain activity.
266 vities operating orthogonal from each other: autocatalytic self-replication of oligomers from native
267 ther a catalytic reaction system contains an autocatalytic, self-sustaining subsystem is unlikely to
269 Such foldamer catalysts are shown to form an autocatalytic set, through which short chains grow into
271 ral conformation of the glycosylasparaginase autocatalytic site without influence from any inhibitor
272 inding of glucosamine-6-phosphate stimulates autocatalytic site-specific cleavage near the 5' of the
273 chemical reaction of a light-sensitive acid autocatalytic solution in which the actuator is immersed
275 ulator of auxin signalling, and modulate the autocatalytic stabilization of auxin signalling output.
278 formation of red fluorescence requires three autocatalytic steps, whereas only two are needed for gre
279 the prebiotic plausibility of each of these autocatalytic subsystems and combinations thereof: self-
280 of superenantiospecificity resulting from an autocatalytic surface explosion reaction of a chiral mol
281 be amplified by reaction mechanisms such as autocatalytic surface explosions which have nonlinear ki
282 on (A --> B, rate constant k(1)) followed by autocatalytic surface growth (A + B --> 2B, rate constan
283 = 1.5(1.1) x 10(-3) h(-1)) followed by fast autocatalytic surface growth (A + B --> 2B, rate constan
284 -> B, rate constant k(1obs)), then (ii) fast autocatalytic surface growth (A + B --> 2B, rate constan
285 2-step, slow continuous nucleation and then autocatalytic surface growth mechanism, A --> B (rate co
286 te constant k1), followed by typically fast, autocatalytic surface growth, A + B --> 2B (rate constan
287 uous nucleation, A --> B (rate constant k1), autocatalytic surface growth, A + B --> 2B (rate constan
288 + B --> C (rate constant k3), and secondary autocatalytic surface growth, A + C --> 1.5C (rate const
289 re we quantitatively analyze the kinetics of autocatalytic surface reduction in an effort to control
290 strate that the activation energy barrier to autocatalytic surface reduction is highly dependent on b
291 to visualize the spontaneous emergence of an autocatalytic system from an aqueous mixture of two chem
293 ues into a cage allowed for the design of an autocatalytic system: oxidation of the methylthio groups
294 tanding the spatiotemporal dynamics of other autocatalytic systems and emphasize the relevance of clu
296 , and it has no known function but undergoes autocatalytic truncations during purification and storag
297 Furthermore, degradation is regulated by the autocatalytic turnover of PUB22, which is stabilized upo
299 bonding picture is presented which predicts autocatalytic water dissociation to be a general phenome
300 f Cwp84, this cleavage does not appear to be autocatalytic, whereas in Cwp13 autocatalysis was demons
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