ライフサイエンスコーパス: autochthonous

1 l (HEV) infection in developed countries are autochthonous.

2 agriculture, as this crop is central to the autochthonous agricultural suite.

3 Both autochthonous and allochthonous DOM is highly bioavailab

4 ol from mango fruit (Mangifera indica L.) of autochthonous and Ataulfo varieties grown in Nayarit, us

5 the separate data, distinguishing wines from autochthonous and nonautochthonous grapes, mono- from th

6 pared the efficacy of multiple approaches in autochthonous and s.c. transgenic adenocarcinoma of the

7 ma (SCC) through deletion of Lkb1 (Stk11) in autochthonous and transplant models.

8 Our studies indicate that the biology of autochthonous and transplanted tumors is quite distinct.

9 response to prostate cancer, we developed an autochthonous animal model based on the transgenic adeno

10 ctor (BAFF)-R (BR3) through interaction with autochthonous B-lymphocyte stimulator (BLyS) ligand in D

11 Segmented filamentous bacteria (SFB) are autochthonous bacteria inhabiting the intestinal tracts

12 Dysbiosis, represented by reduction in autochthonous bacteria, is present in both saliva and st

13 owed that extended control of advanced-stage autochthonous brain tumors is achieved following adoptiv

14 donor lymphocytes is critical for control of autochthonous brain tumors.

15 C in 3 SV40 large T (Tag)-driven conditional autochthonous cancer models with different immune status

16 id mechanics with modern techniques in other autochthonous cancers may be warranted.

17 stration of therapeutic IR to mice harboring autochthonous cancers reduced treatment toxicity without

18 the perfusion, or alter the growth of these autochthonous carcinomas.

19 of T. cruzi infection-the fifth reported US autochthonous case-would have been missed without his mo

20 Sequences from autochthonous cases formed a single cluster very similar

21 We report two autochthonous cases in Spain.

22 Sporadic autochthonous cases of hepatitis E have been reported re

23 s, such as in Louisiana and Texas, there are autochthonous cases of leprosy among native-born America

24 Here, we report three autochthonous cases of scrub typhus caused by O. tsutsug

25 le of fermented musts from Prieto Picudo, an autochthonous Castilla y Leon (Spain) red grape variety

26 NTERPRETATION: Although the current risk for autochthonous CHIKV transmission in Canada is very low,

27 We developed risk maps for autochthonous CHIKV transmission in Canada under recent

28 The risk for autochthonous CHIKV transmission under recent climate is

29 sterols, which can be used as biomarkers of autochthonous (cholesterol, cholestanol, brassicasterol,

30 atitis (AIH), has been hampered by a lack of autochthonous chronic animal models.

31 aracterised Negroamaro red wines, made by an autochthonous cultivar of Southern Italy, by linking vol

32 In the United States, autochthonous cutaneous leishmaniasis caused by infectio

33 ata are compatible with the hypothesis of an autochthonous development of the Minoan civilization by

34 as approximately 9-fold increase of the mean autochthonous DF incidence rate in Zhongshan.

35 In the regression tree models, the mean autochthonous DF incidence rate increased approximately

36 his need, because they mimic spontaneous and autochthonous disease progression.

37 ty and quantity of overall allochthonous and autochthonous DOM as well as associated DBP formation ar

38 Allochthonous and autochthonous DOM shared some spectra, but included uniq

39 quatina lagoon (SE Italy) was compared to an autochthonous (Eriphia verrucosa) and to a commercial cr

40 ates, social science analysis has focused on autochthonous factors and paid less attention to the way

41 ome, with previous HE, relative abundance of autochthonous families decreased whereas potentially pat

42 are likely to be important sources of marine autochthonous FDOM, which may accumulate in the deep oce

43 h Onchocerca volvulus was investigated in an autochthonous focus caused by the migration of infected

44 The competition between the autochthonous fungal/bacterial communities and T. versic

45 eveloped an adeno-associated virus-mediated, autochthonous genetic CRISPR screen in glioblastoma.

46 phagy in prostate cancer, we generated a new autochthonous genetically engineered mouse model (GEMM)

47 Using an autochthonous glioma mouse model, we demonstrated that m

48 study of various wines derived from rare and autochthonous grape varieties of north-western Italy.

49 There are autochthonous grapevine varieties, such as Vitis vinifer

50 elevated oxidation stress but also served as autochthonous H2O2 resource to trigger CPT release for c

51 a, is an anomaly with extreme frequencies of autochthonous haplogroups of Near Oceanian origin; simul

52 With regards to Papuan influence, autochthonous haplogroups support the hypothesis of a lo

53 event clinically relevant carcinogen-induced autochthonous HCC in mice.

54 event clinically relevant carcinogen-induced autochthonous HCC in mice.

55 reduced the incidence of carcinogen-induced autochthonous HCC.

56 g the tumor prevention of carcinogen-induced autochthonous HCC.

57 Autochthonous hepatitis E has been observed with growing

58 be a case of acute liver injury caused by an autochthonous hepatitis E that resolved under steroid tr

59 this clinical scenario, we developed a novel autochthonous HPV-positive oral tumor model to track res

60 Autochthonous HPV-positive oral tumors possessing an act

61 dy tracks the course of MEKi treatment in an autochthonous imageable murine model of melanoma from in

62 nt Repeat (MVR) analysis in a sample of >100 autochthonous individuals from the Basque Country, along

63 COL-EGFP mice and transgenic mice developing autochthonous intestinal adenomas.

64 ricted genetic ablation of murine TRAIL-R in autochthonous KRAS-driven models of non-small-cell lung

65 nufactured from milk with deliberately added autochthonous lactic acid bacteria (LAB) or commercial s

66 survival of mice that spontaneously develop autochthonous, lethal pancreatic carcinomas.

67 development of both induced and spontaneous autochthonous liver cancer in mice.

68 n oil producers (NW Spain) in recovering old autochthonous Local olive fruits has increased substanti

69 In an autochthonous lung adenocarcinoma model driven by activa

70 genous p53 expression leads to regression of autochthonous lymphomas and sarcomas in mice without aff

71 Factors intrinsic to the mice that host the autochthonous mammary carcinomas were also not responsib

72 ed with chemotherapy to elicit regression of autochthonous mammary gland tumors in MMTV-Neu mice.

73 Therefore, a transgenic mouse model of autochthonous mammary tumor development and progression

74 allografts generated from previously treated autochthonous medulloblastomas compared with those from

75 boost immunization could effectively prevent autochthonous melanoma in tumor-prone transgenic mice, p

76 iation, motility, and hyperplasia and, in an autochthonous melanoma model, results in increased tumor

77 noma using both transplantable B16 tumor and autochthonous melanoma models.

78 One such species is Vibrio cholerae, an autochthonous member of estuarine, riverine, and marine

79 V.cholerae lives as an autochthonous microbe in estuaries, rivers and coastal w

80 ustacean exoskeletons), where it lives as an autochthonous microbe.

81 The effects of fermentation by autochthonous microbial starters on phenolics compositio

82 BTV-systems) and compared with the effect of autochthonous microbiota (NB-systems).

83 4-HNE can act as an autochthonous mitotic spindle poison in normal colonic e

84 Using an autochthonous model of colitis-associated cancer (CAC) a

85 Kras-induced tumorigenesis in vivo using an autochthonous model of lung adenocarcinoma with concomit

86 eased metastasis in transplant models and an autochthonous model of lung adenocarcinoma.

87 at RNA combination therapy is possible in an autochthonous model of lung cancer and provide preclinic

88 Finally, in an autochthonous model of NSCLC in the mouse, let-7g expres

89 An autochthonous model of pancreatic ductal adenocarcinoma

90 eate the natural history of metastasis in an autochthonous model of pancreatic ductal adenocarcinoma

91 Using a well-established autochthonous model of PDAC (PKC), we show that inflamma

92 a in the context of an oncogenic Kras-driven autochthonous model of PDAC, the authors demonstrated th

93 In an autochthonous model of prostate cancer, we have previous

94 or tumor-promoting role of T reg cells in an autochthonous model of tumorigenesis, and they reveal th

95 uman cancers of a similar type, making these autochthonous model systems useful for additive engineer

96 To study T cell responses to tumors in an autochthonous model, we expressed a CD8 T cell epitope S

97 al interactions, in addition to confirmatory autochthonous models and/or genetically engineered model

98 This model expands the limited repertoire of autochthonous models of clinically aggressive thyroid ca

99 enty-two Macedonian red wines, including ten autochthonous monovarietal Vranec wines produced with di

100 Using autochthonous mouse melanoma models we identified the me

101 ong-term persistence, capacity to infiltrate autochthonous mouse melanomas, thrive in their microenvi

102 or Bmi1 in intestinal tumorigenesis using an autochthonous mouse model in which Apc was conditionally

103 Altogether, we generated a novel autochthonous mouse model of ABC-DLBCL that could be use

104 Here, we utilize a macrophage-dependent autochthonous mouse model of breast cancer to demonstrat

105 ical evidence that resistance to BRAFi in an autochthonous mouse model of melanoma is associated with

106 ses cell:cell repulsion and metastasis in an autochthonous mouse model of pancreatic adenocarcinoma-w

107 Here we adapted a genetically engineered, autochthonous mouse model of sarcomagenesis to investiga

108 om human tumors and a genetically engineered autochthonous mouse model of soft-tissue sarcomas (STSs)

109 athered from human sarcoma patients, a novel autochthonous mouse model, and mechanistic analyses, we

110 ation of candidate genes in well-established autochthonous mouse models of cancer.

111 er genes in the lung and other tissues using autochthonous mouse models.

112 lls enhances TCR gene therapy efficacy in an autochthonous mouse tumor model.

113 r-1(+) cells from both implantable (4T1) and autochthonous (mouse mammary tumor virus-polyomavirus mi

114 ls, as well as distinct Kras- or Braf-driven autochthonous murine cancer models.

115 ze drug response in an inducible RAF-driven, autochthonous murine model of melanoma incorporating a f

116 In LKB1-null cells derived from an autochthonous murine model of melanoma with activated Kr

117 n enzymatic agent can ablate stromal HA from autochthonous murine PDA, normalize IFP, and re-expand t

118 e examined the DNA methylation pathway in an autochthonous murine prostate cancer model, transgenic a

119 In this study, we used a model of autochthonous murine prostate cancer to evaluate the eff

120 between the vasculature of transplanted and autochthonous murine tumors and indicate that their susc

121 Instead, the autochthonous nature of the mammary carcinomas and their

122 ce, pharmacologic treatment of mice carrying autochthonous NSCLCs with a gamma-secretase inhibitor (G

123 Four clones from cultivars autochthonous of the Emilia Romagna region were selected

124 ular basis with the objective of classifying autochthonous old grapevine varieties.

125 oducers (NW Spain) in recovering the ancient autochthonous olive varieties Brava and Mansa has increa

126 Enhanced autochthonous organic matter deposition to the benthic z

127 different taxa over less than 200 km(2): the autochthonous P. perezi, along with the alien P. ridibun

128 transfer of FAP-CAR T cells also restrained autochthonous pancreatic cancer growth.

129 e biologic mechanisms of SMO inhibition, two autochthonous pancreatic cancer models (Kras(G12D); p16/

130 dy indicate that the pig meat, in particular autochthonous pig meat, may be considered a functional f

131 lated to enhance antitumor responses against autochthonous primary neoplastic growth.

132 gher than present, and resulted in increased autochthonous primary production as recorded by total or

133 with minimal disease significantly inhibited autochthonous primary tumor growth.

134 We contrast our analysis of autochthonous primary tumors to other studies involving

135 Signalosome appears to be initiated through autochthonous production and cognate binding of CD154 (C

136 One component (C5) was related to recent autochthonous production.

137 productive and exhibits reduced diversity of autochthonous prokaryotes in its interior.

138 Using an autochthonous prostate cancer model in which hemagglutin

139 In an autochthonous prostate cancer model, in which tumor-reac

140 However, slower-growing, autochthonous PTEN-deficient prostate tumors that did no

141 nts into overlying waters could increase the autochthonous quality of DOM in shallow microtidal estua

142 e I inhibitor to target rRNA synthesis in an autochthonous Rb/p53-deleted mouse SCLC model and found

143 tter define the chemical profile of Campania autochthonous red grape varieties, we analysed the pheno

144 The autochthonous scavenged skeleton was preserved in mangro

145 efficiently test combination therapies in an autochthonous setting.

146 ring hindlimb ischemia and for the growth of autochthonous skin tumors.

147 Autochthonous SNL meat showed a higher nutraceutical qua

148 ion than WLHPoA, an aquatic DOM dominated by autochthonous sources.

149 zation and biofilm formation, differing from autochthonous substrates in the upper layers of the ocea

150 titumor immune response in a syngeneic fully autochthonous system (FBL-3 erythroleukemia cells, C57BL

151 ow spontaneous angiogenesis in a conditional autochthonous system, implicate the angiopoietins as dow

152 In stool microbiome, relative autochthonous taxa abundance reduced in previous HE, alo

153 Specific microbial families (autochthonous taxa negatively and Enterobacteriaceae pos

154 rse HRQOL, higher inflammation and decreased autochthonous taxa relative abundance compared to the re

155 Specifically beneficial, autochthonous taxa were negatively linked with brain and

156 In tumors arising in the autochthonous TiRP transgenic model of melanoma associat

157 olera, Vibrio cholerae, has been shown to be autochthonous to riverine, estuarine, and coastal waters

158 onfirming the hypothesis that V. cholerae is autochthonous to the aquatic environment and is a commen

159 We previously established the autochthonous transgenic adenocarcinoma mouse prostate (

160 Here, the T-bet pathway in the autochthonous transgenic adenocarcinoma mouse prostate m

161 We have used the autochthonous transgenic adenocarcinoma of mouse prostat

162 issue specimens derived from the spontaneous autochthonous transgenic adenocarcinoma of the mouse pro

163 The autochthonous transgenic adenocarcinoma of the mouse pro

164 multiple subcutaneous isograft models and an autochthonous transgenic model of mammary tumorigenesis,

165 was performed in prostatic tissues of TRAMP (autochthonous transgenic mouse model), human CaP patient

166 Using autochthonous transgenic mouse models for inducible FGFR

167 us serotypes in many tropical countries, and autochthonous transmission in Europe and the USA.

168 ent except Antarctica, causing outbreaks and autochthonous transmission in previously disease-free re

169 Although there has been no autochthonous transmission of CHIKV in Canada, there is

170 ll help define the spatial limits of current autochthonous transmission of dengue and chikungunya vir

171 agrees with the geographical distribution of autochthonous transmission of the agent of Lyme borrelio

172 and NF-kappaB activation when compared with autochthonous transplanted mutant mice.

173 Mice with extensive, but not minimal autochthonous tumor burdens demonstrated a significantly

174 marked variation in the intrinsic ability of autochthonous tumor cells to accumulate p53 and undergo

175 en simultaneously administered enabled acute autochthonous tumor debulking and resulted in durable cl

176 Autochthonous tumor formation is induced by CRISPR-Cas9-

177 ient mice to investigate its contribution to autochthonous tumor formation.

178 and complete regression of well-established autochthonous tumor in a setting where the host immune s

179 Src inhibitors have not been examined in an autochthonous tumor model that permits assessment of eff

180 n of antiangiogenic therapy in a spontaneous autochthonous tumor model, which may more closely resemb

181 ve shown that TRAIL can reduce tumor growth, autochthonous tumor models have generated conflicting re

182 els, little is known about their function in autochthonous tumor models in vivo.

183 topes of HER-2/neu leads to the outgrowth of autochthonous tumors after immunizing HER-2/neu transgen

184 d small-animal ultrasound imaging to monitor autochthonous tumors and showed that treatment with the

185 (VEGFR2) monoclonal antibody, on spontaneous autochthonous tumors and their early generation transpla

186 dels, demonstrating that genetically defined autochthonous tumors can be rapidly generated and quanti

187 ved from these more physiologically relevant autochthonous tumors compared with previous studies in t

188 o at least one anti-BCC drug of the parental autochthonous tumors from which they arise.

189 Spontaneous autochthonous tumors in aged C3H mice consisted of s.c.

190 ial protection and therapy against growth of autochthonous tumors in transgenic mouse models of breas

191 genetic validation of therapeutic targets in autochthonous tumors on a genome-wide scale.

192 what effects GCN2 loss has on the growth of autochthonous tumors that arise in their native microenv

193 dels, including genetic models, we show that autochthonous tumors that lacked T cell infiltration and

194 erstand the role of T(CD8) in the control of autochthonous tumors, we have used mice of the RIP1-Tag4

195 of spontaneous, as well as oncogene-induced, autochthonous tumors.

196 umor growth in large (500 mm(3)) spontaneous autochthonous tumors.

197 beta gene segments in the immune response to autochthonous tumors.

198 nduced mutp53 ablation, allotransplanted and autochthonous tumours curb their growth, thus extending

199 ion translates into more clinically relevant autochthonous tumours in genetically engineered mouse mo

200 SPR-Cas9 system has been adapted to generate autochthonous tumours in mice, but how these tumours com

201 oited this mechanism to treat autologous and autochthonous tumours successfully.

202 Alterations in the autochthonous vaginal microflora can predispose women to

203 Effects in E. coli were compared to an autochthonous wastewater community.

204 ives of this study were to (i) isolate newly autochthonous yeast strains from the Tikves region of Ma

205 us spread to Brazil with the first report of autochthonous Zika transmission in the Americas in March

206 suspected and laboratory-confirmed cases of autochthonous ZIKAV transmission.