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1 Methods A total of 477 HCT recipients (236 autologous, 128 reduced-intensity allogeneic, 113 myeloa
2 ter they received intravitreal injections of autologous adipose tissue-derived "stem cells" at one su
3 romal lamina transplantation with or without autologous adipose-derived adult stem cell recellulariza
4 ntial benefits of its recellularization with autologous adipose-derived adult stem cells remains uncl
6 safety and efficacy of adding intra-arterial autologous adipose-derived MSCs into STK to standardized
10 d in IVIg, but the reverse was true when the autologous and allogeneic IgG concentrations were augmen
11 However, phase I and II clinical trials with autologous and first-generation stem cells have yielded
12 ing psoriatic Mo-MDSC are unable to suppress autologous and heterologous CD8 T-cell proliferations, d
16 9-6.41%] implant, 9.89% (95% CI: 4.98-19.1%) autologous, and 26.7% (95% CI: 20.4-34.4%) no reconstruc
17 trial, axicabtagene ciloleucel (axi-cel), an autologous anti-CD19 chimeric antigen receptor (CAR) T-c
18 for the future development of personalized, autologous anticancer vaccines with broad applicability.
20 lutinin were able to present the antigens to autologous antigen-specific CD4(+) T cells in a major hi
21 ere capable of presenting vaccine antigen to autologous antigen-specific memory CD4(+) T cells ex viv
22 pendent conversion of endothelial cells into autologous authentic engraftable haematopoietic stem cel
23 domized comparison of safety and efficacy of autologous (auto) versus allogeneic (allo) bone marrow-d
26 rrent status in generating and transplanting autologous beta-cells for diabetes cell therapy, highlig
27 cally compliant culture system, we show that autologous BK virus-specific T cell lines can be reliabl
28 patients demonstrated enhanced responses to autologous blasts in vitro, and primed CD56bright cells
30 An in vitro bovine liver model perfused with autologous blood via the portal vein at three flow rates
31 different HA content and particle size with autologous bone and empty defects, at two time points (6
32 apy, osteonecrotic defects were treated with autologous bone graft, which were simulated by using bon
33 It represents a promising alternative to autologous bone grafting, which is considered the curren
34 ndomized clinical trials, most of which used autologous bone marrow mononuclear cells, have found onl
35 eering the use of high-dose chemotherapy and autologous bone marrow transplantation in patients with
36 esigned to assess the safety and efficacy of autologous bone marrow-derived aldehyde dehydrogenase br
37 he responses after intracoronary infusion of autologous bone marrow-derived mononuclear cells (BMCs)
38 d standard treatment of the defect site with autologous bone tissue did not improve bone formation or
39 ostoperative complications after implant and autologous breast reconstruction in patients undergoing
41 with improvements in deep sequencing of the autologous cancer have provided new insight into the mol
42 checkpoint modulators elicits potent in situ autologous cancer vaccination, resulting in an efficacio
47 To evaluate the safety and bioactivity of autologous CD34+ cell (CLBS10) intracoronary infusion in
48 rvest and were randomized 1:1 to receive (1) autologous CD34+ cells (minimum 10 mol/L+/-20% cells; N=
49 investigational therapy involved infusion of autologous CD34+ cells transduced with the elivaldogene
50 2, and used as antigen-presenting cells for autologous CD4(+) T cells (CD4(+) T cells coincubated wi
51 -moDCs strongly potentiated proliferation of autologous CD4(+) T cells and CD8(+) T cells and product
53 ate the safety and efficacy of administering autologous CD4(+) T cells that are genetically engineere
54 with differentially fluorescent dye-labeled autologous CD8(hCXCR5) and untransduced CD8 T cells and
57 the swine were randomly assigned to receive autologous cell therapy (endothelial cells, n = 4) or co
58 of studies evaluating safety and efficacy of autologous cell therapy for intractable peripheral arter
59 quipoise may no longer be guaranteed because autologous cell therapy has the potential to modify the
60 ime would provide significant advantages for autologous, cell-based therapies in regenerative medicin
64 sed the production of IL-2 and IFNgamma from autologous cells; a process mediated through increased p
66 he results of clinical studies investigating autologous cellular therapies in urological malignancies
68 modified by the anti-FcmuR CAR, purged their autologous CLL cells in vitro without reducing the numbe
69 reparation of human saphenous vein (HSV) for autologous coronary and peripheral arterial bypass proce
70 ficiency virus type 1 (HIV-1) efficacy of an autologous dendritic cell (DC)-based HIV-1 vaccine loade
71 ivered intratumorally, including infusion of autologous dendritic cells and even tumor-reactive T lym
73 o quantified by measuring the suppression of autologous effector T-cell proliferation by Treg cell in
77 scintigraphy performed with (99m)Tc-labeled autologous erythrocytes or historically with (99m)Tc-sul
78 ication of the pre-grafting expansion during autologous fat transplantation in breast reconstruction,
80 fiscal consequence of hospital variation for autologous free flap breast reconstruction is unknown.
85 f scalable constructs that are vascularized, autologous, functional, implantable, cost-effective, and
86 novations centered around the development of autologous gene therapies targeting private somatic muta
88 hat solely neutralized pseudovirions bearing autologous GP1 provided enhanced neutralization of MACV
89 mplant group (difference, -3.8; P = .001) or autologous group (-2.2; P = .04), nor was physical well-
90 rapies, including immunoablation followed by autologous haematopoietic stem cell transplantation, mes
91 trial showed no benefit of mobilisation and autologous haematopoietic stem-cell transplantation (HSC
95 9 and 2012 and received transplantation with autologous hematopoietic CD34+ cells that were modified
99 ansfer of normal globin-producing genes into autologous hematopoietic stem cells (HSCs) are in clinic
101 glioblastoma received 1 or more infusions of autologous HER2-CAR VSTs (1 x 106/m2 to 1 x 108/m2) with
104 f complex tissues from hiPSCs using a single autologous hiPSCs as source and generates a range of str
108 liciting the role of donor and host Tregs in autologous HSCT is not possible in humans due to the aut
109 rimary outcome was MG disease activity after autologous HSCT measured by frequency of emergency depar
111 1118 allogeneic HSCTs (allo-HSCTs) and 1625 autologous HSCTs (auto-HSCTs) among 54 transplant center
113 ecently developed humanized mouse model with autologous human immune and liver cells, human liver and
114 ptively transferred cells in the presence of autologous human immune cells prior to clinical use.
115 se findings demonstrate that the presence of autologous human immune cells supports the in vivo survi
116 tated peptides with high-affinity binding of autologous human leukocyte antigen (HLA) molecules.
120 ibute to their poor autoproteolysis, causing autologous immune stimulation upon necrotic exposure.
122 rast, the incidence of SSI was similar after autologous IR (9.8% [177 of 1799]), DR (13.9% [19 of 137
123 after implant IR and 1.11 [range, 0-6] after autologous IR) compared with women who did not have a co
125 incidence of SSI and NIWCs after implant and autologous IR, DR, and SR breast procedures after mastec
128 nteers were randomized to a single standard, autologous, leukoreduced, packed red cell transfusion af
129 institutional animal care and use committee, autologous liver endothelial cells were grown from core
130 ents with cancer through the use of ACT with autologous lymphocytes has provided an opportunity to di
133 6-month, phase 1 trial to determine whether autologous mesenchymal stem cells, applied in a bioabsor
137 can be grown in large numbers in vitro, and autologous MSCs transfused into tuberculosis patients ha
140 lls (iNSCs) have significant potential as an autologous, multifunctional cell therapy for stroke, whi
141 MM) patients displayed superior responses to autologous myeloma targets, and furthermore, CD56bright
142 , V3 immunogenicity was eliminated while the autologous NAb response was unchanged.IMPORTANCE Trimeri
148 d to bridge long, nonhealing nerve gaps, the autologous nerve graft (autograft), has several drawback
149 losely mimic the native Env spike can induce autologous neutralizing antibodies (NAbs) against relati
150 tive-like CZA97.012 SOSIP.664 trimers induce autologous neutralizing antibodies (NAbs) efficiently in
151 erior germinal center formation and enhanced autologous neutralizing antibodies against the neutraliz
152 a HIV-1 transmitted/founder (TF) Env induces autologous neutralizing antibodies that can not only neu
156 cades of investigation, it is now known that autologous neutralizing antibody responses and their sel
157 s comparable to HIV-1 in humans and elicited autologous neutralizing antibody responses typical of HI
161 IFN-gamma and IL-17A cytokine production by autologous, NTHi-specific lung CD4(+) T cells, and cytok
165 hat combined of intranodal administration of autologous or allogeneic DRibbles together with anti-OX4
166 with hematologic malignancies who underwent autologous or allogeneic HCT to inpatient palliative car
173 ase after induction treatment, with adequate autologous peripheral blood stem-cell collection, and wi
174 d adult monocyte-derived DCs cultured in 10% autologous plasma or in newborn cord, infant, adult, and
176 gineered extracellular matrix populated with autologous pluripotent cells can result in de-novo organ
177 ion and lower developmental competence, with autologous populations of mitochondrial isolate at ferti
178 e-AIT sera, the presence of heterologous and autologous post-AIT sera significantly reduced the aller
179 1.2 mg RSV in situ gel with a 1:1 mixture of autologous PRF and HA bone graft in the surgical treatme
180 lar Class II furcation defects compared with autologous PRF and HA bone graft placed after open-flap
182 e clinical and radiographic effectiveness of autologous PRF versus PRF + HA in treatment of IBDs in p
183 IBDs in 17 patients were treated either with autologous PRF with open flap debridement (OFD) or OFD a
184 ronic periodontitis were treated either with autologous PRF with open flap debridement (OFD+PRF) or O
186 ed by EBV-infected cells, to B cell lines or autologous primary B lymphocytes also promoted specific
188 lls persisted for an average of 201 days for autologous recipients and 51 days for allogeneic recipie
190 rom 1998 to 2007 and who underwent immediate autologous reconstruction (n = 2637), immediate implant-
193 for baseline values, patients who underwent autologous reconstruction had greater satisfaction with
194 4; P = .035), whereas patients who underwent autologous reconstruction had increased pain interferenc
195 ear after mastectomy, patients who underwent autologous reconstruction were more satisfied with their
198 eeks of refrigerated storage, transfusion of autologous red cells to healthy human volunteers increas
201 whether such effects could be reproduced in autologous settings by TCR gene-engineered lymphocytes.
203 llogeneic cells show several advantages over autologous sources: they can be produced in large quanti
204 ributed in vitro to tumor cell resistance to autologous-specific CTL and in vivo to the in situ recru
205 d toward consolidative high-dose therapy and autologous stem cell rescue with improving long-term sur
207 py among 235 patients initially treated with autologous stem cell transplant (ASCT) at Mayo Clinic.
210 odgkin's lymphoma who previously received an autologous stem cell transplant or two previous multiage
212 e inhibitors (91%), alkylating agents (91%), autologous stem cell transplantation (78%), thalidomide
213 rge B-cell lymphoma (DLBCL) not eligible for autologous stem cell transplantation (ASCT) or having re
214 se induction and up-front consolidation with autologous stem cell transplantation (ASCT) remain contr
215 patients (Deauville score </=2) proceeded to autologous stem cell transplantation (ASCT) whereas PET-
217 eceiving systemic chemotherapy or subsequent autologous stem cell transplantation for treatment of he
218 actory response, a consolidation by means of autologous stem cell transplantation may offer a greater
219 select patients with chemosensitive disease, autologous stem cell transplantation should be considere
227 enetic disorders involves transplantation of autologous stem cells that have been genetically correct
229 eted sequencing on cryopreserved aliquots of autologous stem-cell products from 401 patients who unde
233 ance therapy or to undergo observation after autologous stem-cell transplantation (120 patients per g
234 rpose Lenalidomide maintenance therapy after autologous stem-cell transplantation (ASCT) demonstrated
235 We hypothesized that in patients undergoing autologous stem-cell transplantation (ASCT) for lymphoma
236 104 study, lenalidomide versus placebo after autologous stem-cell transplantation (ASCT) was investig
237 y of myeloablative chemotherapy supported by autologous stem-cell transplantation (ASCT), as an alter
240 Some patients with DHL undergo consolidative autologous stem-cell transplantation (autoSCT) to reduce
241 cal Hodgkin's lymphoma after failure of both autologous stem-cell transplantation and brentuximab ved
242 ecommended for pediatric patients undergoing autologous stem-cell transplantation and for adult and p
243 ontrolled trials, adult patients who undergo autologous stem-cell transplantation at experienced cent
245 is chemotherapy refractory or relapsed after autologous stem-cell transplantation have a grim prognos
246 mib, and dexamethasone (RVD) with or without autologous stem-cell transplantation, followed by lenali
247 after initial immunochemotherapy followed by autologous stem-cell transplantation, patients have rela
251 ular chimera), engineered to express several autologous T cell epitopes and sequences derived from th
254 atient-derived human melanoma cells by their autologous T cells in vitro and potentiates responses to
256 psed/refractory HL or ALCL were infused with autologous T cells that were gene-modified with a retrov
261 ) are being pursued as a source of cells for autologous therapies, many of which will be aimed at age
264 andidates elicit predominantly tier 1 and/or autologous tier 2 virus neutralizing antibody (NAb) resp
265 -1 neutralizing antibodies and induce robust autologous tier-2 neutralization, unlike a first-generat
266 re done to procure tumour tissue to generate autologous TIL cultures, which then underwent large scal
267 followed by a single intravenous infusion of autologous TILs and high-dose interleukin-2 [720 000 IU/
268 first report describing adoptive transfer of autologous TILs to mediate objective tumour regression i
271 SOSIP.4mut elicited a higher ratio of tier 2 autologous titers versus tier 1 V3-sensitive titers than
272 time, indicating the transition from narrow autologous to broad heterologous neutralization over tim
273 fractory to both; (31 [70%]) had received an autologous transplant, and (30 [62%]) had high-risk cyto
274 les from 12 patients who developed TMN after autologous transplantation for Hodgkin lymphoma or non-H
275 itical aspects of vascular repair, including autologous transplantation of bone marrow-derived stem c
277 ctions of impaired IP-DPSCs, suggesting that autologous transplantation of IFN-gamma-accelerated IP-D
278 cells (HSPCs) from FA patients, either after autologous transplantation or infusion into immunodefici
280 it from early treatment intensification with autologous transplantation, as indicated by the possibil
282 py has been developed as a method to perform autologous transplantations of a patient's own stem cell
283 Surgeon B contrasted the pros and cons of an autologous transverse rectus abdominis muscle flap recon
284 , we used viable human lung tumor slices and autologous tumor antigen-specific T-lymphocyte clones to
285 phocytes (TIL) expressing PD-1 can recognize autologous tumor cells, suggesting that cells derived fr
287 dministration of dendritic cells pulsed with autologous tumor lysate combined with cyclophosphamide i
289 ) trials to date have focused on transfer of autologous tumor-specific cytotoxic CD8(+) T cells; howe
290 sought to determine if adoptive transfer of autologous tumour-infiltrating lymphocytes (TILs) could
292 ut, elicited a significantly higher ratio of autologous versus V3-directed neutralizing antibody resp
294 e, together with evidence of contemporaneous autologous virus neutralization, supports the proposal t
295 ciency have had relative success; the use of autologous virus-specific cytotoxic T cells has proved e
296 nvs) induced neutralizing Abs against Tier 2 autologous viruses expressing cognate envelope (Env).
298 , 1,632 patients (n = 1,139 implant, n = 493 autologous) were included; 1,183 (72.5%) responded to 1-
299 g preservation up to 24 hours (24H) by using autologous whole donor blood circulating within an ex vi
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