ライフサイエンスコーパス: autonomic failure

1 resist the onset of hypoglycemia-associated autonomic failure.

2 l higher in Parkinson's disease than in pure autonomic failure.

3 inopathies, multiple system atrophy and pure autonomic failure.

4 relate in a predictable way with severity of autonomic failure.

5 and dementia, sleep disorders, hyposmia and autonomic failure.

6 ccording to the presence or absence of early autonomic failure.

7 ith impairment of baroreflex function due to autonomic failure.

8 the pathogenesis of hypoglycemia-associated autonomic failure.

9 It was indistinguishable from pure autonomic failure.

10 ajor role in causing hypoglycemia-associated autonomic failure.

11 hypoglycemia causing hypoglycemia associated autonomic failure.

12 the pathogenesis of hypoglycemia-associated autonomic failure.

13 3.2 [7.0-18.6] mU/L), and patients with pure autonomic failure (12.5 [5.6-18.2] mU/L).

14 productive problems, and weight loss suggest autonomic failure, a phenotype that is consistent with t

15 with sympathetic denervation due to primary autonomic failure (AF).

16 Multiple system atrophy is characterized by autonomic failure along with motor symptoms of parkinson

17 Patients with pure autonomic failure also had very low levels of plasma nor

18 in 19 patients with severe NOH (8 with pure autonomic failure and 11 with multiple-system atrophy).

19 opsy from 4 patients with MSA with prominent autonomic failure and 5 patients with no neurological di

20 onsistent phenotype of chronic diarrhea with autonomic failure and a length-dependent axonal, predomi

21 tes, are at risk for hypoglycemia-associated autonomic failure and the resultant vicious cycle of rec

22 disease, 54 multiple system atrophy, 20 pure autonomic failure) and 38 controls.

23 nically deficient sympathetic activity (pure autonomic failure), and 15 normal age-matched controls.

24 cerebellar, and mixed), 19 people with pure autonomic failure, and 27 healthy participants.

25 c dysfunction (multiple system atrophy, pure autonomic failure, and baroreflex failure) were compared

26 ors contribute to asthenia, such as anaemia, autonomic failure, and muscular abnormalities.

27 heral tissues were associated with diarrhea, autonomic failure, and neuropathy.

28 ases, some being indistinguishable from pure autonomic failure, and support the concept that ganglion

29 NTERPRETATION: Patients presenting with pure autonomic failure are at high risk of phenoconverting to

30 d ratio 1.02, P = 0.001); and (vi) degree of autonomic failure as measured by a validated composite a

31 Autonomic dysfunction was defined as autonomic failure at autonomic function testing or 2 of

32 and MSA-C are similar and severe symptomatic autonomic failure at diagnosis is associated with worse

33 ich is usually beneficial in primary chronic autonomic failure, does not seem to be beneficial in the

34 ing; festination or retropulsion; concurrent autonomic failure; dramatic response to anticholinergics

35 g exercise would prevent exercise-associated autonomic failure (EAAF).

36 In MSA early autonomic failure, female gender, older age of onset, a

37 (median +/- interquartile range) and had had autonomic failure for 5 +/- 7 years.

38 In those with MSA who had central autonomic failure, GH concentrations were unchanged (MSA

39 's disease, multiple system atrophy and pure autonomic failure groups all had lower cerebrospinal flu

40 ine (NAC), prevented hypoglycemia-associated autonomic failure (HAAF) and impaired activation of vent

41 s the key feature of hypoglycemia-associated autonomic failure (HAAF) and, thus, the pathogenesis of

42 Hypoglycemia-associated autonomic failure (HAAF) constitutes one of the main cli

43 The concept of hypoglycemia-associated autonomic failure (HAAF) in diabetes posits that recent

44 a phenomenon termed hypoglycemia-associated autonomic failure (HAAF) in diabetes.

45 Hypoglycemia-associated autonomic failure (HAAF) occurs commonly in patients wit

46 his effect, known as hypoglycemia-associated autonomic failure (HAAF), occurs in diabetic patients as

47 poglycemia, known as hypoglycemia-associated autonomic failure (HAAF), occurs in diabetic patients in

48 Hypoglycemia-associated autonomic failure (HAAF)-reduced autonomic (including ad

49 responses, known as hypoglycemia-associated autonomic failure (HAAF).

50 Approximately 50% of patients with primary autonomic failure have supine hypertension.

51 rthostatic hypotension and confirmed chronic autonomic failure in 31 (4.8%) patients.

52 e neurodegenerative disease characterized by autonomic failure in addition to various combinations of

53 , the key feature of hypoglycemia-associated autonomic failure in diabetes, in humans.

54 , the key feature of hypoglycemia-associated autonomic failure in diabetes, in humans.

55 t hypoglycemia-associated neuroendocrine and autonomic failure in healthy humans.

56 f hypoglycemia-associated neuroendocrine and autonomic failure in healthy humans.

57 impaired autonomic synaptic transmission and autonomic failure in mice implicates an antibody-mediate

58 favourable course than PSP-P, and that early autonomic failure in MSA is associated with shorter surv

59 tonomic failure, multiple system atrophy, or autonomic failure in Parkinson disease), orthostatic hyp

60 re likely to develop hypoglycemia-associated autonomic failure in response to recurrent hypoglycemic

61 inant cerebellar involvement) in eight, pure autonomic failure in two and Parkinson's disease in one.

62 ial as a therapy for hypoglycemia-associated autonomic failure in type 1 diabetes.

63 unifying concept of hypoglycemia-associated autonomic failure in type 1 diabetes.

64 ography and a human neurological model (pure autonomic failure), in which peripheral autonomic denerv

65 This sleep-related hypoglycemia-associated autonomic failure, in the context of imperfect insulin r

66 cy) is a rare congenital disorder of primary autonomic failure, in which neurotransmitters NE and epi

67 Parkinson's disease and pure autonomic failure involve differential dopaminergic vers

68 Autonomic failure is an integral component of diabetic n

69 assess whether such hypoglycemia-associated autonomic failure is due to actual brain damage, male Sp

70 r characterised by a variable combination of autonomic failure, levodopa-unresponsive parkinsonism, c

71 neurodegenerative disorder characterised by autonomic failure, manifested as orthostatic hypotension

72 Thus, hypoglycemia-associated autonomic failure may be due in part to a relative exces

73 In chronic autonomic failure (pure autonomic failure, multiple system atrophy, or autonomic

74 out SH (PD - SH, n = 19), patients with pure autonomic failure (n = 8), and controls (n = 16).

75 h the multiple system atrophy (n=5) and pure autonomic failure (n=4) groups, all initial pressures we

76 in the USA, and the effects of phenotype and autonomic failure on prognosis.

77 Patients with pure autonomic failure or parkinsonism and sympathetic neuroc

78 static hypotension (OH) (PD+OH) or with pure autonomic failure (PAF) have markedly decreased myocardi

79 s with multiple system atrophy (MSA) or pure autonomic failure (PAF), we studied the effect of oral y

80 stem atrophy (MSA), and 8 patients with pure autonomic failure (PAF).

81 ion (PD+OH, PD-No-OH); in patients with pure autonomic failure (PAF, a Lewy body disease without park

82 features of the disease include progressive autonomic failure, parkinsonism, and cerebellar ataxia l

83 e small group of patients retaining the pure autonomic failure phenotype had very low plasma norepine

84 neurodegenerative disorder with symptoms of autonomic failure plus parkinsonism, cerebellar ataxia,

85 In chronic autonomic failure (pure autonomic failure, multiple syst

86 2 weeks later the autonomic failure recurred but again responded to treatm

87 e system atrophy had younger age at onset of autonomic failure, severe bladder/bowel dysfunction, pre

88 Participants with severe symptomatic autonomic failure (symptomatic orthostatic hypotension,

89 rtain disorders, such as the primary chronic autonomic failure syndromes; it can complicate a variety

90 no signs of central neurodegeneration (pure autonomic failure), two with parkinsonism responsive to

91 Autonomic failure was severe: CASS was 7.2+/-2.3 (maximu

92 een shown to prevent hypoglycemia-associated autonomic failure, we hypothesized that OR blockade duri

93 nts with multiple systems atrophy (MSA) with autonomic failure, we sought to test the hypothesis that

94 nts with a known or provisional diagnosis of autonomic failure were excluded from analysis.

95 One hundred patients who presented with pure autonomic failure were recruited at 5 medical centers in

96 arkers that predict which patients with pure autonomic failure will develop Parkinson disease, dement

97 attern of severe and progressive generalised autonomic failure with severe adrenergic and sudomotor f

98 serum in healthy people and those with pure autonomic failure (with peripheral lesions), but not in

99 Of the 83 cases of MSA, 42 (53.2%) had autonomic failure within 2 years of disease onset.

100 The presence of autonomic failure worsens prognosis in the diabetic stat