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1 sed by premature differentiation and is cell-autonomous.
2 on, indicating that glial pathology was cell autonomous.
3 al neurons, most E46K aSyn toxicity was cell autonomous.
4 s in D. melanogaster nephrocytes caused cell-autonomous accumulation of the endocytic tracer atrial n
6 e first demonstrations of postsynaptic, cell-autonomous actions of endocannabinoids in the mammalian
8 We report that loss of HVEM leads to cell-autonomous activation of B cell proliferation and drives
9 Here we elucidate the structural basis of autonomous activation of CLL B cells, showing that BcR i
11 s in a paracrine manner, in part by non-cell autonomous activation of the GLI transcription factor.
13 e report the consequences of prolonged, cell-autonomous activation of the UPR(MT) in C. elegans dopam
14 al image analysis distinguishes between cell-autonomous (active) displacements and convection caused
15 d roles of Notch in cancer, focusing on cell autonomous activities that may be either oncogenic or tu
16 dependent protein kinase II (CaMKII) and its autonomous activity generated by Thr-286 autophosphoryla
17 ause a marked decrease in Ca(2+)-independent autonomous activity, however S137L and P138S mutants dis
18 ctive in Thr85-autophosphorylation dependent autonomous activity, whereas the A329T mutation rendered
19 -free shapeshifting opens new ways to design autonomous actuators, drug-release systems and active im
20 progress that has been made toward building autonomous agents with human-like abilities, and highlig
21 opathologic finding parallels an age-related autonomous aldosteronism and abnormal aldosterone physio
22 consistently lower for symbiotic compared to autonomous algae, suggesting nutritional constraints upo
24 is to inspire and support new generations of autonomous and adaptive molecular devices fueled by self
27 e antigen-binding fragment (Fab or Fv) is an autonomous and complete unit for antigen recognition.
33 ipulation in a tumor cell can have both cell-autonomous and nonautonomous effects and suggest that at
37 TN neurons encode arterial PCO2 /pH via cell-autonomous and paracrine mechanisms, and via input from
38 to accelerate leukaemogenesis, through cell-autonomous and possibly non-cell-autonomous mechanisms,
40 bditis elegans to mammals have revealed cell-autonomous and systemic DDR mechanisms that orchestrate
43 of Smo inhibition is haploinsufficient, cell autonomous, and correlates with the accumulation of OR-c
45 bolus resuscitation, both semiautonomous and autonomous approaches were more efficient in goal-direct
46 systematically investigated the role of cell-autonomous AR in different prostate epithelial cell type
47 ressed prostate only in the presence of cell-autonomous AR, supporting a facultative model for CARN s
48 tion of Grb14-deficient hepatocytes was cell-autonomous as it was also observed in primary cell cultu
50 lethal in Drosophila This lethality is cell-autonomous, as directed expression of the mutant Fic(E24
51 lleagues (2017) find that tumors trigger non-autonomous autophagy in neighboring cells and distant or
52 gaster malignant tumour model, that non-cell-autonomous autophagy is induced both in the tumour micro
55 The circadian clock, an endogenous and cell-autonomous biological timekeeper that produces rhythmic
57 rk, a PDMS microchannel-based, colorimetric, autonomous capillary chip provides a multiplexed and sem
61 engineered systems can serve as testbeds for autonomous chemical robots composed of biological and sy
63 ircuits having novel capabilities, including autonomous chiral inversion of DNA sequence information
65 mine (Meth) and running wheel (RW)] restores autonomous circadian activity in arrhythmic SCN-lesioned
67 an give rise to temporal desynchrony between autonomous circadian oscillators in different regions, w
68 that this mechanism is mediated not via cell-autonomous clock properties, but rather through altered
72 main were phosphorylated more efficiently by autonomous compared with Ca(2+)/CaM-stimulated CaMKII ac
74 chanisms underlying these roles involve cell-autonomous control of signaling and gene expression by p
75 s no effect of IL-1R2 deficiency on the cell-autonomous cytokine response to IL-1beta in the tested c
80 oncentration of DNMT3B are critical for cell-autonomous de novo DNA methylation in somatic cells.
82 We report that CLYBL loss leads to a cell-autonomous defect in the mitochondrial B12 metabolism an
83 ocess of autophagy, which is an ancient cell autonomous defense pathway that utilizes ER-derived memb
86 nergy storage what is vital for portable and autonomous device operation with numerous advantages as
88 ol, encompassing human iPS cell preparation, autonomous differentiation, purification, and subsequent
89 hlight how dynamic shape transformations and autonomous division can be activated by spatially confin
91 NAs, but no intact EBV-DNA, linking non-cell-autonomous EBER1 presence with skin inflammation in pred
94 tion was due to a placental trophoblast cell-autonomous effect of autophagic activity, not to alterat
96 medium-transfer experiment in which the cell-autonomous effects of 5-aza was dissociated, CHOP ablati
99 in Ras(V12) clones also results in non-cell-autonomous effects with autophagy, cell proliferation an
102 ve mechanism that allows muscle to integrate autonomous energy demand with systemic energy storage an
106 ditional Trp53 inactivation activates a cell-autonomous epithelial-to-mesenchymal transition program
109 tion of this pathway also reduced tumor cell-autonomous expression of target genes for the transcript
110 aging, selective vulnerability and non-cell-autonomous factors such as alpha-synuclein cell-to-cell
112 aling promotes B lymphopoiesis in a non-cell-autonomous fashion in vitro, and depletion of the Hh eff
113 ocking out D2Rs eliminates the ADP in a cell-autonomous fashion, confirming that this ADP depends on
116 e-associated stemness is an unexpected, cell-autonomous feature that exerts its detrimental, highly a
117 We provide genetic evidence of a non-cell-autonomous feedback pathway regulating Fgf9, Fgf18 and P
118 experimental verification of a new class of autonomous ferromagnetic swimming devices, actuated and
119 aling while simultaneously inducing the cell-autonomous Fgf signaling inhibitor Dusp4 within the firs
120 nistic link between light conditions and the autonomous floral promotion pathway in Arabidopsis.
122 These effects are shown to be primarily cell autonomous, from loss of alpha3(V) chains normally produ
124 nd by Hox-TALE factors, supporting a lineage autonomous function of Shox2 in osteogenic lineage fate
126 ic operations promote the entrainment of CA3-autonomous gamma oscillators bilaterally, synchronizing
127 glycans biosynthesized by the canonical cell-autonomous glycosylation pathway, but subjected to remod
129 s by a process other than the canonical cell-autonomous glycosylation that occurs within the intracel
130 ure of this material is its capacity for the autonomous healing of cracks when operating at high temp
132 uggest an essential role for endogenous cell-autonomous human skeletal muscle oscillators in regulati
133 ether with paradoxically robust, rapid, cell-autonomous IL-2 and IFNgamma production, equip liver CD8
137 gy are evolutionarily conserved arms of cell-autonomous immunity that restrict replication of intrace
139 PER synthesis happens in a programmable, autonomous, in situ and environmentally responsive fashi
142 the importance of gonadal hormones and cell-autonomous influences in mammals versus strictly cell-au
145 n Wallerian axon degeneration; instead, axon autonomous, intrinsic mechanisms are thought to be the p
146 en this novel extrinsic pathway and the axon autonomous, intrinsic pathways that have become establis
148 -LIKE3 (SMXL3), SMXL4, and SMXL5 act as cell-autonomous key regulators of phloem formation in Arabido
153 ce have designed crucial ingredients towards autonomous learning: curiosity and intrinsic motivation,
154 bryonic cortical neurogenesis and novel cell-autonomous Lgl1 functions controlling RGP-mediated glia
159 adult neural stem/progenitor cells in a cell-autonomous manner in vitro and migration of their progen
161 last are very precisely controlled in a cell autonomous manner, after quiescence extrinsic factors co
162 f/+)Alb-cre(+/0) mice of each sex, in a cell-autonomous manner, but was greater in livers from the fe
163 na fide anti-inflammatory Mvarphis in a self-autonomous manner, whereas M-CSF-treated CD16(+) monocyt
178 reorganization are determined by neuron-cell-autonomous mechanisms and by interactions among neurons,
179 ur results implicate both autonomous and non-autonomous mechanisms as key mediators of regional cell
182 Moreover, post-transplantation non-cell-autonomous mechanisms restore the numbers of interstitia
183 esides the classic paracrine mechanism, cell-autonomous mechanisms that involve induction of ER stres
184 us cytotoxicity of IFN was augmented by cell-autonomous mechanisms that operated independently of the
185 it stability is controlled both through cell-autonomous mechanisms that regulate some aspects of exci
186 This severe pathology occurred through cell autonomous mechanisms that triggered Purkinje cell death
187 hrough cell-autonomous and possibly non-cell-autonomous mechanisms, in a manner that was reversed by
192 ays the conceptual foundation for developing autonomous microfluidic transport devices driven by bact
193 , and implicate a role for IL-34 in non-cell-autonomous, microglial-dependent neurodegeneration in HD
195 INE-1, also known as L1), the only currently autonomous mobile transposon in humans, occupies 17% of
197 ffice for complex chemical dynamics and that autonomous molecular systems can be designed via molecul
198 of the local concentration gradient to drive autonomous motion of colloidal particles in the highly c
199 overcome, leading to the first generation of autonomous motors and pumps on scales ranging from micro
200 s 2D colony a 'SEAM' (self-formed ectodermal autonomous multizone), and previously demonstrated that
201 cocultures to investigate potential non-cell autonomous neuroprotective factors influencing AbetaO to
202 n in the HD brains, contributing to non-cell-autonomous neurotoxicity in HD.SIGNIFICANCE STATEMENT Hu
206 integration of previous reinforced learning autonomous of the current outcome value and is implicit
207 tegrated LED used for excitation, allows for autonomous operation in on-site or in-the-field applicat
213 induce oscillations of auxin response: cell-autonomous oscillations, Turing-type patterning, and tis
219 V capsids.IMPORTANCE We first report that an autonomous parvovirus, HBoV1, helps the replication of a
221 ermore, FOF2 mRNA expression is regulated by autonomous pathway gene FCA, and the repressive effect o
223 ikely roles for genes in the photoperiod and autonomous pathways in generating switchgrass flowering
224 m, which is driven by oncogene-mediated cell-autonomous pathways, the unique physiology of the tumor
228 heta frequency bursts to understand how cell autonomous, postsynaptic activity leads to synapse elimi
229 ve diseases is hypothesized to be a non-cell-autonomous process that may be mediated by the productiv
230 nd that seizure termination is a plastic and autonomous process, reflected in increased duration of i
233 triggers a previously unsuspected, non-cell-autonomous program to activate STAT3 signalling in hepat
234 ant RAS has been shown to stimulate non-cell autonomous proliferation in malignancy and suggests that
235 55-fold genome coverage, allowing us to map autonomous promoter activity genome-wide in K562 cells.
237 e ability of embryonic cells to couple their autonomous random motility to non-autonomous signals ari
238 dynamics with chemical modulators indicated autonomous regenerative capacity in both leader and foll
240 ATP7A suggesting that intestine-specific non-autonomous regulation of ATP7A abundance may serve as a
241 ose PDGF-A/PDGFRalpha signalling as a tissue-autonomous regulator of CIL by controlling N-cadherin up
242 ation of dynamin as one of the essential and autonomous regulators of focal adhesion maturation sugge
243 ithorax complex (BX-C) of Drosophila delimit autonomous regulatory domains that drive parasegment-spe
244 taining pH-responsive polymer layer leads to autonomous release of the encapsulated payload upon gast
245 a Cre-expression construct identified a cell-autonomous requirement for paxillin in migrating neurons
246 e CNS myelination defect results from a cell-autonomous requirement for THAP1 in the OL lineage and i
248 T2, to demonstrate a mammary epithelial cell-autonomous requirement of CBL and CBL-B in the maintenan
250 omous roles in cell flattening from non-cell-autonomous requirements for MTs in regulating proliferat
251 identify stress-mediated ER-phagy as a cell-autonomous response mobilized by STING-dependent sensing
252 controlling deployment of constitutive cell-autonomous responses during infection have remained elus
253 lements represent the only currently active, autonomous retrotransposon in the human genome, and they
256 These findings demonstrate a direct and cell-autonomous role for E2F activators in human cancer.
261 is study, we identify an unexpected non-cell autonomous role of epidermal polarity proteins, molecula
264 onal dysfunction, our findings reveal a cell-autonomous role of pejvakin in maintaining stereocilia a
266 eal a previously unappreciated critical cell-autonomous role of TNF on monocytes for their survival,
271 Automatically-identified click types from autonomous seafloor recorders without verifiable species
272 marrow chimera experiments revealed a T cell-autonomous selective disadvantage of CD6(-/-) T cells du
273 rated by unveiling the constructed nature of autonomous selfhood, and explaining why social clusterin
274 aits and its implications on the capacity of autonomous selfing in both allopatric and sympatric popu
275 oral traits and the relative contribution of autonomous selfing to total seed set varies geographical
276 impact on floral morphology and capacity of autonomous selfing, most likely as a way to reduce the p
278 cal reactions with potential applications to autonomous sensing, distributed computing, and biomedica
279 icrobeads was completed in <20 s followed by autonomous sequential delivery of 100 muL of bacteria sa
281 ty of homotypic BcR contacts leading to cell-autonomous signalling reconciles the existence of a shar
282 uple their autonomous random motility to non-autonomous signals arising from the expansion of the ext
283 transgenes, and discover conditions for cell-autonomous silencing in animals with tissue-specific res
286 levels of functionalities (temporal control, autonomous structures, motion and work generation, infor
288 ation sites of yeast Cdh1 are organized into autonomous subgroups and act through separate mechanisms
289 r the synthesis of Ecdysone and produce cell-autonomous survival defects, but the mechanisms by which
292 ge preceding aggregation, detecting non-cell-autonomous toxicity and evaluating how some of the main
293 strategy for gene activation by tethering an autonomous transcription activation domain (TAD) to an i
297 elements are the smallest but most abundant autonomous transposable elements in prokaryotic genomes,
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