ライフサイエンスコーパス: autoradiography

1 ed by an external optical imaging system and autoradiography.

2 in vivo small-animal PET imaging and ex vivo autoradiography.

3 e at 24 h on small-animal PET/CT imaging and autoradiography.

4 ippocampus were confirmed by ex vivo PET and autoradiography.

5 ir and cold florbetapir compound and digital autoradiography.

6 ed in 18 mice using immunohistochemistry and autoradiography.

7 was detected with (64)Cu-DOTA-ECL1i by using autoradiography.

8 ere confirmed by ex vivo biodistribution and autoradiography.

9 mus and cortical regions of the pig brain by autoradiography.

10 tors by using quantitative in vitro receptor autoradiography.

11 vestigated in vivo with PET and ex vivo with autoradiography.

12 s performed using high-resolution (3)H-DPCPX autoradiography.

13 ured in the striatum using in vitro receptor autoradiography.

14 3.8 +/- 0.8 vs. 10.3 +/- 2.3, P < 0.01), and autoradiography.

15 was detected by phosphoprotein staining and autoradiography.

16 e same states as reported by 2-deoxy-glucose autoradiography.

17 orated by ex vivo scintillation counting and autoradiography.

18 stribution of (18)F-LMI1195 was evaluated by autoradiography.

19 assessed ex vivo by immunohistochemistry and autoradiography.

20 hin the lymph nodes was studied with digital autoradiography.

21 Additionally, we performed postmortem autoradiography.

22 hrome oxidase (CO) and CTB-Au, or dipped for autoradiography.

23 level correlated well with tracer uptake on autoradiography.

24 bridizations as well as dopamine transporter autoradiography.

25 icantly correlated with uptake quantified by autoradiography.

26 C-FDG uptake distributions using dual-tracer autoradiography.

27 e quantified by gamma-counting and imaged by autoradiography.

28 in, as measured by (125)I alpha-Bungarotoxin autoradiography.

29 water-replete rats by quantitative receptor autoradiography.

30 anges in biodistribution were assessed using autoradiography.

31 was evaluated by in vitro binding assay and autoradiography.

32 ATP, and then washed, dried and analyzed by autoradiography.

33 ignal was confirmed by CT coregistration and autoradiography.

34 n with M-CSF or GM-CSF by using quantitative autoradiography.

35 B cells or were further analyzed via digital autoradiography.

36 man BC specimens was compared using in vitro autoradiography.

37 9m)Tc-rhAnnexin V-128, or no radiotracer for autoradiography.

38 hAnnexin V-128) were determined with digital autoradiography.

39 CO) histochemistry analysis or [(3)H]proline autoradiography.

40 xtracts were tested for binding by ELISA and autoradiography.

41 PET/CT imaging, biodistribution studies, and autoradiography.

42 he activity distribution as determined using autoradiography.

43 lammation, shown on immunohistochemistry and autoradiography.

44 stribution of radionuclides visualized using autoradiography.

45 orated by ex vivo scintillation counting and autoradiography.

46 its neural correlates [2-deoxyglucose (2-DG) autoradiography].

47 (0.41+/-0.04 versus 0.73+/-0.1, P=0.014) and autoradiography (1.1+/-0.3 versus 2.8+/-0.2 P=0.001).

48 by qRT-PCR, in situ hybridization, receptor autoradiography ([(125)I]OVTA binding), and immunohistoc

49 istribution data (4 and 24 h) and whole-body autoradiography (24 h) in mice with Raji tumor xenograft

50 ontrast to nearby regions equaling that from autoradiography; a lower contrast was found using the co

51 sing [(125)I] alpha-bungarotoxin (alpha-BGT) autoradiography, alpha7 expression was measured in the O

52 Behavioural and receptor autoradiography analyses demonstrated that DATKO grafts

53 Ex vivo PET and autoradiography analysis further confirmed our in vivo P

54 Both autoradiography analysis of sciatic nerves excised from

55 y PET, PET/CT, or PET/MR imaging followed by autoradiography analysis.

56 Regional CBF distribution was examined by autoradiography and analyzed by statistical parametric m

57 rated for [(125)I]11d and [(11)C]11e through autoradiography and biodistribution studies, imaging of

58 ted for NMDAR binding specificity in ex vivo autoradiography and brain biodistribution studies.

59 PR and SSTR2 expression analyzed by in vitro autoradiography and by quantitative reverse transcriptas

60 ter injection was also evaluated via ex vivo autoradiography and compared with amyloid-beta plaque de

61 tissues was assessed with in vitro receptor autoradiography and compared with an established peptidi

62 was validated ex vivo by gamma-counting and autoradiography and compared with cleaved caspase-3 (CC3

63 as quantified on arterial cryosections using autoradiography and compared with CXCR4 and RAM-11 (macr

64 luated for tracer distribution using digital autoradiography and compared with histologic markers of

65 clinical breast cancer specimens by in vitro autoradiography and correlated this with corresponding m

66 and evaluated for (18)F-EF5 distribution by autoradiography and EF5 binding by immunohistochemistry.

67 We measured TK activity by plaque autoradiography and expression of frameshifted and unfra

68 mall-animal PET imaging and combined ex vivo autoradiography and fluorescence immunohistochemistry.

69 Autoradiography and fluorescent-based microscopic imagin

70 Autoradiography and focused ion beam/scanning electron m

71 ined in vivo using PET/CT and in vitro using autoradiography and gamma-counting of tumor tissue.

72 Tracer uptake was confirmed by autoradiography and gamma-well counting, and specificity

73 Autoradiography and hematoxylin-eosin staining were perf

74 (111)In-cetuximab-F(ab')(2) was evaluated by autoradiography and histologic markers evaluated by immu

75 Autoradiography and histology results were consistent wi

76 to the location of scar tissue identified by autoradiography and histology.

77 d, frozen, and sliced for serial dual-tracer autoradiography and histology.

78 tivity in infarcted tissues was confirmed by autoradiography and histology.

79 Deformable registration of autoradiography and histopathology images acquired from

80 ligands, PBB3 and AV-1451, by fluorescence, autoradiography and homogenate binding assays with homol

81 Autoradiography and immunoblotting data showed that muta

82 Autoradiography and immunoblotting studies suggested tha

83 [3H]PiB autoradiography and immunocytochemistry for beta-amyloid

84 Tumors were assessed ex vivo by digital autoradiography and immunofluorescence for microscopic v

85 For autoradiography and immunohistochemical evaluation, addi

86 In addition to imaging, autoradiography and immunohistochemistry experiments wer

87 Autoradiography and immunohistochemistry further confirm

88 d, and alternating sections were analyzed by autoradiography and immunohistochemistry to determine th

89 PET imaging, biodistribution, autoradiography and immunohistochemistry, and ex vivo HG

90 r 15- to 16-mo-old mice correlated well with autoradiography and immunostaining (i.e., increased (18)

91 in slices of Sprague-Dawley rats by in vitro autoradiography and in living rats by in vivo small-anim

92 quantitative (125)I-labelled leptin in vitro autoradiography and in situ hybridisation, respectively.

93 take were compared ex vivo using dual-tracer autoradiography and in vivo using PET in different xenog

94 yacrylamide gel electrophoresis, followed by autoradiography and mass spectrometry.

95 methodology for deformable coregistration of autoradiography and microscopy images acquired from a se

96 en they underwent micro-SPECT/CT, along with autoradiography and oil red O staining of tissues.

97 86192 was evaluated in tumors using in vitro autoradiography and PET with mice bearing bilateral PD-L

98 biodistribution was investigated by in vitro autoradiography and positron emission tomography (PET) i

99 sities as determined by human tissue section autoradiography and preclinical in vivo PET studies in t

100 termined in cynomolgus monkeys by whole-body autoradiography and radioanalysis of ocular tissues.

101 in brains of untreated mice was analyzed by autoradiography and saturation analysis using [(3)H]-ABP

102 Autoradiography and scintillation counting confirmed the

103 then sliced, and the slices were imaged with autoradiography and stained with hematoxylin and eosin.

104 In vivo results were confirmed by autoradiography and staining of human CD3 after postmort

105 ively accurate and spatially concordant with autoradiography and the small-animal PET examination.

106 y, sectioned, with the sections subjected to autoradiography and thionine counterstaining.

107 Ex vivo autoradiography and TSPO/CD68 immunostaining were also p

108 protein synthesis inhibition as measured by autoradiography and was also observed with cycloheximide

109 action for inflammatory markers, 3) receptor autoradiography, and 4) transcriptome analysis in the hi

110 radiography, [F-18]-AV-1451 nuclear emulsion autoradiography, and [H-3]-AV-1451 in vitro binding assa

111 periments with rat brain membranes, in vitro autoradiography, and blocking and displacement experimen

112 hematoxylin and eosin staining, (3)H-PK11195 autoradiography, and CD11b immunohistochemistry.

113 s determined by quantitative ultrastructural autoradiography, and confirmed by analysis of quantum do

114 Here, we used 64Cu-PET-CT, MRI, autoradiography, and fluorescence imaging to track the k

115 tomography (SPECT)/computed tomography (CT), autoradiography, and fluorescence microscopy.

116 stigations were followed by biodistribution, autoradiography, and fluorescence-activated cell sorting

117 ubicin treatment was quantified by microPET, autoradiography, and gamma counting.

118 earts, by Pro-Q-Diamond/Sypro-Ruby staining, autoradiography, and immunoblotting using phosphoserine-

119 gs were analyzed using fluorescence imaging, autoradiography, and immunohistochemistry.

120 ll-binding experiments using flow cytometry, autoradiography, and internalization assays with various

121 ts along the lines of fluorescence staining, autoradiography, and mass spectrometry.

122 The results from biodistribution, autoradiography, and microPET imaging showed higher [(18

123 Biodistribution studies, autoradiography, and PET experiments were performed to d

124 11)C with positron emission tomography, root autoradiography, and radiometabolite flux analysis to un

125 terogeneity of RP782 uptake was confirmed by autoradiography, and specificity was demonstrated using

126 y-derived indices correlated poorly with the autoradiography- and PET-derived ones (R = 0.06-0.54).

127 When radiolabeled precursors and autoradiography are used to investigate turnover of prot

128 , ex vivo biodistribution (BD), and in vitro autoradiography (ARG) experiments.

129 ystem and compared with quantitative ex vivo autoradiography as a gold standard.

130 ion of the radionuclide was visualized using autoradiography at predefined time points.

131 Quantitative autoradiography at the ultrastructural level shows that

132 The autoradiography binding density of (18)F-fluorodeprenyl-

133 In vitro and ex vivo autoradiography binding experiments in Wistar and in mGl

134 Autoradiography binding patterns were consistent with th

135 cryosections of the brains were evaluated by autoradiography, by histology, and for EBD fluorescence

136 Within the tumor, (111)In-RGD2 autoradiography coincided with vascular integrin alphavb

137 ceptors using quantitative in vitro receptor autoradiography combined with a detailed analysis of the

138 Brain autoradiography confirmed clot dissolution in recombinan

139 Both external optical imaging and autoradiography confirmed the high signal from the (18)F

140 In contrast, quantitative autoradiography confirmed the linkage of Chrna7 genotype

141 Autoradiography confirmed the spatiotemporal profile.

142 (111)In-cetuximab-F(ab')(2) as determined by autoradiography correlated well with the distribution of

143 ce in (18)F-PBR06 uptake in these mice using autoradiography (cortex/striatum: 1.13 +/- 0.04 vs. 0.96

144 nd in the absence of motion, one can achieve autoradiography, CT, and PET image registration with spa

145 Quantitative autoradiography demonstrated a 1.6-fold induction of (18

146 Comparison of oil red O staining with autoradiography demonstrated areas of discordance betwee

147 Autoradiography demonstrated complete ablation of KOR bi

148 Ex vivo autoradiography demonstrated high uptake of (18)F-FPPRGD

149 The autoradiography-derived indices differed significantly (

150 ed indices correlated significantly with the autoradiography-derived ones (R = 0.57-0.85), but the va

151 rly gene expression and (14)C 2-deoxyglucose autoradiography during mother-to-infant fear transmissio

152 Ex vivo autoradiography experiments were performed after the fin

153 and in vivo (small-animal PET/CT imaging and autoradiography) experiments in the presence of succinat

154 ensity in PET (F(DF=3) = 5.9, P = 0.001) and autoradiography (F(DF=3) = 4.2, P = 0.008).

155 We applied [F-18]-AV-1451 phosphor screen autoradiography, [F-18]-AV-1451 nuclear emulsion autorad

156 In all three cases, autoradiography failed to show detectable [F-18]-AV-1451

157 Activity concentrations were obtained using autoradiography for 20 specimens extracted with 18- and

158 on specific brain structures using receptor autoradiography, found that the desensitization treatmen

159 )F-FTC-146 in rats were assessed via PET/CT, autoradiography, gamma counting, and high-performance li

160 (2) [(3)H] muscimol-related autoradiography grains were distributed in all six neoco

161 (3) [(3)H] muscimol-related autoradiography grains were localized to the cortical ar

162 The combination of uptake studies and autoradiography greatly increases our understanding of h

163 vo retention of [F-18]-AV-1451 and performed autoradiography, [H-3]-AV-1451 binding assays, and quant

164 scanner correlated with results obtained by autoradiography, histologic evaluation, and polymerase c

165 the PET/CT scan, animals were sacrificed for autoradiography, histologic work-up, or RNA expression a

166 Here we use electron microscopy, autoradiography, histology and preclinical and clinical

167 Autoradiography, histology, and immunohistochemistry wer

168 was to solve this problem by using combined autoradiography-histology methods.

169 of tumors and lymph nodes was performed via autoradiography, histopathology, and immunohistochemistr

170 Autoradiography identifies activity concentrated in area

171 d tomography/computed tomography imaging and autoradiography illustrated spatial distribution within

172 The Hoechst-to-autoradiography image registration was done using rigid

173 m was clearly visualized in PET and in vitro autoradiography images of control animals and was no lon

174 cer uptake was determined on micro-SPECT and autoradiography images of tumor sections.

175 Digital autoradiography images revealed a nonhomogeneous distrib

176 Total error of registration of autoradiography images to the histopathologic images acq

177 Autoradiography images were correlated with histopatholo

178 The response of autoradiography imaging plates was calibrated using dumm

179 es through a combination of fluorescence and autoradiography imaging.

180 Autoradiography, immunohistochemical staining, and HGF E

181 specimens including radioactivity counting, autoradiography, immunohistochemistry, and antigen densi

182 In vitro PET autoradiographies in rat brain sections with this radiot

183 d specificity were evaluated by quantitative autoradiography in apolipoprotein E-deficient (apoE(-/-)

184 o aneurysm and its specificity were shown by autoradiography in carotid aneurysm.

185 nd distribution determined by tissue-section autoradiography in preclinical species and humans.

186 opharmacologic evaluations included in vitro autoradiography in rat brain and PET scans on anesthetiz

187 to Abeta plaques in the AD brain by ex vivo autoradiography in transgenic AD model mice.

188 ith a commercial small-animal PET system and autoradiography in tumor-bearing mice.

189 2-deoxyglucose (2DG) uptake, as measured by autoradiography, in response to unilateral forepaw stimu

190 At autoradiography, intravenous pretreatment with the selec

191 Using thin tissue section autoradiography, it is possible to visualize the spatial

192 l animal positron emission tomography (PET), autoradiography, microdialysis and molecular biology in

193 s evaluated for CCR2 with immunostaining and autoradiography (n = 6, COPD) with (64)Cu-DOTA-ECL1i.

194 ell counting of 0.84, P < 0.000001, and with autoradiography of 0.88, P < 0.000001).

195 from 1 d (enzyme assays) to up to 3 months (autoradiography of [(3)H]-labeled proteins).

196 Autoradiography of [(3)H]-LY450295 binding to stargazer

197 Binding characteristics were determined by autoradiography of AD brain sections in vitro and using

198 tribution of (18)F-AV-45 in mice and ex vivo autoradiography of AD transgenic mice (APPswe/PSEN1) wit

199 oal was to develop a method for quantitative autoradiography of biopsy specimens (QABS), to use this

200 Autoradiography of biopsy specimens obtained using 5 typ

201 Finally, ex vivo autoradiography of brain sections from amyloid precursor

202 Autoradiography of brain slides confirmed that the accum

203 Quantitative autoradiography of coronal brain slices from F2 mice der

204 ibution of (18)F-FDG was assessed by digital autoradiography of frozen tissue sections.

205 In vitro autoradiography of human and animal pancreatic sections

206 on preclinical work, on quantitative in vivo autoradiography of human tumor slices, and on human data

207 Microscopic ex vitro autoradiography of kidney showed F-Dapa binding to the a

208 In vitro autoradiography of postmortem human brain sections showe

209 Ex vivo brain autoradiography of radioligands was performed at subacut

210 in each group) and were killed afterward for autoradiography of the brain.

211 Similar results were obtained from ex vivo autoradiography of the ipsilateral versus contralateral

212 vitro using gamma-well counting and digital autoradiography of tumor tissue.

213 anatomical considerations and identified by autoradiography of veins following uptake of (14)C-label

214 ptor (alpha2A-AR) expression was assessed by autoradiography on brain slices, and Galphai proteins ex

215 and selectivity for the GRPR during receptor autoradiography on human cancer samples (IC(50) in nM: G

216 n of 50% (IC50) values were determined using autoradiography on human tissues with (125)I-GLP-1(7-36)

217 Autoradiography on rat brain sections indicated that the

218 binding measures with postmortem human brain autoradiography outcomes showed a high correlation for t

219 of (18)F-FET uptake were observed in PET and autoradiography (P > 0.05).

220 was observed on both PET/MRI (P < 0.001) and autoradiography (P < 0.005) in the operated nerve in thi

221 indicated by ex vivo gamma-well counting and autoradiography (P < 0.05).

222 istribution over time using a combination of autoradiography, positron emission tomography (PET)/comp

223 es correlate strongly with the corresponding autoradiography protein levels.

224 small-animal PET were highly correlated with autoradiography (r > 0.99) and with each other (r = 0.97

225 The mean error of Hoechst to (18)F-FLT autoradiography registration (both images acquired from

226 either of the in vitro methods, and digital autoradiography resulted in the highest measurements.

227 Similarly, PET/CT and autoradiography results demonstrated accumulation of (18

228 Autoradiography revealed [3H]PiB binding in neocortical

229 Autoradiography revealed peak tracer uptake in the thick

230 t analysis of in vivo and ex vivo images and autoradiography revealed significantly higher Tc-99m-HL9

231 Autoradiography revealed that [(11)C]DASB was sensitive

232 ing for fibrillary beta-amyloid, and ex vivo autoradiography served as terminal gold standard assessm

233 SPECT/CT and autoradiography showed a very heterogeneous distribution

234 Quantitative autoradiography showed an increase in N/OFQ receptor bin

235 Ex vivo autoradiography showed excellent spatial correlation wit

236 Autoradiography showed high (11)C-donepezil binding (dis

237 take could be observed on PET scans, whereas autoradiography showed slight radiotracer accumulation i

238 In vitro rat brain autoradiography showed specific binding of [ (18)F]3h in

239 Both PET/CT and autoradiography showed that [(64)Cu]-NPs entered the let

240 Ex vivo autoradiography showed that regional brain distribution

241 Autoradiography showed that the localizations of radioac

242 g using a silicon-strip detector for digital autoradiography, staining for histologic characterizatio

243 ich correlated well with biodistribution and autoradiography studies (i.e., much higher tracer uptake

244 ific binding of [3H]CUMI-101 by quantitative autoradiography studies in postmortem baboon and human b

245 -9 with AD brain tissue sections and ex vivo autoradiography studies in transgenic mouse brain sectio

246 Furthermore, in vitro autoradiography studies of [(18)F]-9 with AD brain tissu

247 sitron emission tomography (PET) and ex vivo autoradiography studies of [(18)F]13 in mice showed high

248 Semiquantitative autoradiography studies on postmortem tissue sections of

249 Ligand binding autoradiography studies showed nicotine and CSE to have

250 Biodistribution and autoradiography studies were also performed to confirm t

251 Biodistribution radiotherapy, imaging, and autoradiography studies were performed in LNCaP, DU145,

252 In vitro receptor autoradiography studies were performed to establish the

253 n identified as a promising I(2) ligand from autoradiography studies, displaying high affinity and go

254 In autoradiography studies, N-(11)C-methyl-JNJ-31020028 rec

255 generation patient brain tissue slices using autoradiography studies.

256 By autoradiography, the TSPO radiotracer binding potential

257 somatostatin (SRIF) receptors using receptor autoradiography; those with high SRIF receptor subtype 1

258 We used autoradiography to characterize central vasopressin 1a r

259 We first used receptor autoradiography to compare MOR binding densities between

260 ave previously used fluorodeoxyglucose (FDG) autoradiography to detect the pattern of metabolic decli

261 human hearts were compared using radiocaine autoradiography to determine that the failing heart has

262 Micro-PET and autoradiography using [(11)C]raclopride confirmed a stro

263 vestigated in competition binding assays and autoradiography using a fresh cardiac thrombus from an e

264 ific activity of the oligonucleotide, and by autoradiography using film, which is cumbersome and incr

265 ted by saturation binding assay and in vitro autoradiography using post-mortem Alzheimer's disease br

266 25)I-pentixafor uptake in the vessel wall on autoradiographies was located in macrophage-rich regions

267 Autoradiography was conducted to determine regional FBzB

268 In vitro receptor autoradiography was performed on 55 NETs, comparing in e

269 stologic samples were available; (68)Ga-PSMA autoradiography was performed on an exemplary case of PE

270 Autoradiography was performed on harvested nerves and mu

271 Autoradiography was performed using technetium-pertechne

272 In vitro receptor autoradiography was performed with (125)I-JR11 and (125)

273 Whole-hemisphere autoradiography was performed with (18)F-fluorodeprenyl-

274 define CGRP receptor binding sites, in vitro autoradiography was performed with [(3)H]MK-3207 (a CGRP

275 Autoradiography was performed with [(3)H]MK-3207 to demo

276 On-the-slide ligand binding autoradiography was used to determine if there were alte

277 Quantitative in vitro receptor autoradiography was used to measure the regional displac

278 ass spectrometry (DESI-MS/MS) and whole-body autoradiography (WBA) were used for chemical imaging of

279 surface sampling probe (LMJ-SSP), whole-body autoradiography (WBA), and high-pressure liquid chromato

280 range of techniques, particularly whole body autoradiography (WBA).

281 the method of in vitro quantitative receptor autoradiography, we demonstrated that-for instance, in n

282 With autoradiography, we determined binding affinities and le

283 Using [(5)S]GTPgamma binding autoradiography, we show that application of flupenthixo

284 stimulated [(35)S]GTPgammaS and [(3)H]ligand autoradiography were assessed by statistical parametric

285 nalysis of vascular integrin alphavbeta3 and autoradiography were completed.

286 (18)F-FET PET scans and ex vivo autoradiography were performed in animals receiving a si

287 Fluorescence microscopy, histopathology, and autoradiography were performed on representative section

288 X-ray computed tomography and autoradiography were performed to identify the spatial l

289 in vivo and ex vivo imaging and quantitative autoradiography were performed.

290 Histochemical analyses and ex vivo autoradiography were ultimately performed in a subset of

291 Subsequently, SPECT imaging and autoradiography were used to determine in vivo binding o

292 stribution studies, and small-animal PET and autoradiography were used to determine the uptake of (64

293 rain glucose uptake (via (14)C-2deoxyglucose autoradiography) were measured.

294 Moreover, autoradiography, which recorded beta particles from (198

295 SPECT and autoradiography with (99m)Tc-scVEGF of tumor cryosection

296 (123)I-PIP autoradiography with human tissue revealed accumulation

297 ion, we used in vivo PET imaging and ex vivo autoradiography with Pittsburgh compound B ((11)C-PIB) a

298 In vitro autoradiography with the 5-HT7R selective radioligand (3

299 n with ER expression was studied by in vitro autoradiography with the GRP-R agonist (111)In-AMBA.

300 wed colocalization of tracer accumulation on autoradiography, with insulin-positive cells and GLP-1R