ライフサイエンスコーパス: autoregulation

1 egree of autoregulation (1 indicates perfect autoregulation).

2 at they result from defective bvgAS positive autoregulation.

3 edicted to be critical for achieving retinal autoregulation.

4 female developmental commitment via positive autoregulation.

5 ade fidelity, for standard models of genetic autoregulation.

6 f regulatory mechanisms in achieving retinal autoregulation.

7 sites, one of which appears to be subject to autoregulation.

8 osteoblast differentiation and negative Bmp autoregulation.

9 plays an active and unique role in cerebral autoregulation.

10 RgdR stimulation of T3S required ler and Ler autoregulation.

11 ogenic tone that underpins tissue blood-flow autoregulation.

12 ific transcriptional response, including its autoregulation.

13 and identified that it is required for cIAP1 autoregulation.

14 smission, providing a novel form of synaptic autoregulation.

15 context, which could underlie translational autoregulation.

16 l perfusion and decreased the lower limit of autoregulation.

17 NA (dADAR) activity and alterations in dADAR autoregulation.

18 clude gld-2 and rnp-8 themselves, suggesting autoregulation.

19 nd 23%, demonstrating effective steady-state autoregulation.

20 ssociated with Lmx1b that suggests a role in autoregulation.

21 remifentanil, provides best preservation of autoregulation.

22 els below those tolerated by cerebrovascular autoregulation.

23 ifferent function: DNA-binding transcription autoregulation.

24 arteries, below the lower limit of coronary autoregulation.

25 onitoring techniques in relation to cerebral autoregulation.

26 vel site of Jak2 phosphorylation and, hence, autoregulation.

27 ome is likely an insult to cerebral vascular autoregulation.

28 period, but decreased thereafter reflecting autoregulation.

29 n cocaine was administered in the absence of autoregulation.

30 gotic tra expression stimulates Sxl-positive autoregulation.

31 ctively functions as a co-repressor for Gfi1 autoregulation.

32 increased expression is limited by negative autoregulation.

33 ase is necessary but not sufficient for pilA autoregulation.

34 nctions, intracranial pressure, and cerebral autoregulation.

35 mulated NFATc1 transcription, confirming its autoregulation.

36 n-mediated scaffold phosphorylation and Fus3 autoregulation.

37 minal centre cells by avoiding BCL6-negative autoregulation.

38 enarios, stable networks had mostly positive autoregulation.

39 which can independently initiate weak Su(H) autoregulation.

40 iding in vivo evidence for mammalian kinesin autoregulation.

41 LEF-1 protein levels and LEF-1 messenger RNA autoregulation.

42 bmodule, which then sustains long-term Su(H) autoregulation.

43 % decrease) in another patient with impaired autoregulation.

44 d 40 mm Hg is used to indicate the degree of autoregulation (1 indicates perfect autoregulation).

45 H) at the lower limit of cerebral blood flow autoregulation (50 mm Hg).

46 tter effect is consistent with BMP7 positive autoregulation, a phenomenon we demonstrate directly.

47 ar-infrared spectroscopy-derived measures of autoregulation accurately detected loss of autoregulatio

48 demonstrate a novel mechanism of eosinophil autoregulation affecting migration and survival mediated

49 emains limited regarding cerebral blood flow autoregulation after cardiac arrest and during postresus

50 ole for sex-dependent mechanisms in cerebral autoregulation after pediatric traumatic brain injury.

51 ogic and pharmacological factors on cerebral autoregulation alongside its clinical relevance with the

52 28 mRNA targets, we found evidence for LIN28 autoregulation and also direct but differing effects on

53 Furthermore, Gle1(InsP6) relieves Dbp5 autoregulation and cooperates with Nup159 in stabilizing

54 n of overrepresented network motifs, such as autoregulation and coregulation of sigma and anti-sigma

55 a positive-feedback loop that includes both autoregulation and JAGGED1 expression.

56 GAF-B domain of CyaB1 ablated cAMP-mediated autoregulation and Na(+) inhibition.

57 rks, to investigate the relationship between autoregulation and network stability and robustness unde

58 n arterial blood pressure below the limit of autoregulation and not absolute mean arterial blood pres

59 tandem repeats to mediate both transcription autoregulation and segregation.

60 Sequential transcription factor autoregulation and subsequent binding to downstream prom

61 ice with Cx40 replaced by Cx45, steady-state autoregulation and TGF were weaker than those in wild-ty

62 mean arterial blood pressure at the limit of autoregulation and the duration and degree to which mean

63 dentified the requirements of c-Abl in BMP-2 autoregulation and the expressions of alkaline phosphata

64 nsion explains the improved dynamic cerebral autoregulation and the reduced cerebral perfusion encoun

65 ominance--mutations which result in stronger autoregulation, and decrease noise in homozygotes, parad

66 ed as leaderless transcripts, and subject to autoregulation, and expression of the toxin component le

67 the neurovascular response, cerebrovascular autoregulation, and ischaemia are critical processes to

68 nt, intracranial pressure, impaired cerebral autoregulation, and outcome remain poorly explored.

69 The structural basis of autoregulation, and whether it affects interactions of S

70 as via Smad and PI3K-AKT signaling pathways, autoregulation, and/or upregulation of Serpine1, a well-

71 ) in one patient with intact cerebrovascular autoregulation; and only inverse responses (-24% decreas

72 proximately 40%) and/or mutations disrupting autoregulation ( approximately 16%) involving the BCL6 g

73 s in outflow facility and retinal blood flow autoregulation are implicated in primary open-angle glau

74 imits a diploid's ability to evolve negative autoregulation as a noise reduction mechanism.

75 ance (P<0.001), indicating impaired coronary autoregulation as its cause.

76 ay, it may be necessary to quantify cerebral autoregulation as well as cerebral metabolism.

77 pressure limits of cerebrovascular pressure autoregulation (assessed with pressure reactivity index)

78 cava to identify the lower limit of cerebral autoregulation at 6 hrs postresuscitation.

79 haled agents sevoflurane appears to preserve autoregulation at all doses, whereas with other agents a

80 suppress Pax6 activity and thus breaks pax6 autoregulation at defined steps during the formation of

81 5%) and explored the lower limit of cerebral autoregulation at patient and population levels.

82 mGluRs is the dominant mode of glutamatergic autoregulation at the mf-CA3 synapse.

83 ns in CBFV are modulated not only by dynamic autoregulation, but also by changes in steady-state cere

84 a provide the only documented mechanisms for autoregulation, but these are incompatible with eukaryot

85 n receptor signaling to NF-kappaB, undergoes autoregulation by a poorly understood inhibitory domain

86 heZ-mediated dephosphorylation that includes autoregulation by CheYp and allowed prediction of CheZ a

87 Negative autoregulation by Dve maintains expression from each enh

88 Inhibition of FOXM1 transcriptional autoregulation by HSP70 leads to the suppression of FOXM

89 sion of the large Rep proteins, it undergoes autoregulation by Rep, it undergoes induction by helper

90 levels revealed DENV-vsRNA-5's role in virus autoregulation by targeting the virus nonstructural prot

91 sgenic rescue also reveals indirect positive autoregulation by the 7 early stripes, without which alt

92 ism that controls fnr expression is negative autoregulation by the active [4Fe-4S] form of FNR.

93 We conclude that Cx40 contributes to RBF autoregulation by transducing TGF-mediated signals to th

94 tested the hypothesis that dynamic cerebral autoregulation (CA) and blood-brain barrier (BBB) functi

95 he individual variability of static cerebral autoregulation (CA) and determined its associations with

96 Cerebral autoregulation (CA) is a key mechanism to protect brain

97 Cerebral autoregulation (CA) is a protective mechanism that maint

98 Cerebral autoregulation (CA) is an important vascular control mec

99 t application and interpretation of cerebral autoregulation (CA) measurements in research and in clin

100 Preventing Plk4 autoregulation causes centrosome amplification, stabiliz

101 es were used to create a color-coded maps of autoregulation - cerebral perfusion pressure relationshi

102 l blood pressure is below the lower limit of autoregulation, cerebral oximetry index approaches 1, be

103 d the noise peak and predicted that negative autoregulation changes reporter expression from bimodal

104 recurrent network motifs, including negative autoregulation, combinatorial regulation, two-gene clock

105 ase in the perfusion pressure lower limit of autoregulation compared to postarrest, normothermic pigl

106 in Escherichia coli have shown that negative autoregulation confers both rapid response times and red

107 lial cell proliferation coupled with altered autoregulation consequent to the development of preglome

108 We found that autoregulation could either suppress or increase the out

109 fects of stimuli employed in cerebrovascular autoregulation (CVA) tests on the brain, without contact

110 Dynamic cerebral autoregulation (dCA) is impaired following stroke.

111 and hypothermia and tested novel measures of autoregulation derived from near-infrared spectroscopy.

112 The operon is subject to strong, negative autoregulation during development by DevS.

113 nNOS inhibition attenuates breakthrough from autoregulation during hypertension as does complete inte

114 x dependently reduces impairment of cerebral autoregulation during hypotension after fluid percussion

115 dependently prevents impairment of cerebral autoregulation during hypotension after fluid percussion

116 fter FPI, SNP does not prevent impairment of autoregulation during hypotension after FPI.

117 lator, prevented sex dependent impairment of autoregulation during hypotension after piglet fluid per

118 f autoregulation accurately detected loss of autoregulation during hypotension.

119 opy accurately identified the lower limit of autoregulation during normothermia and hypothermia in pi

120 terlinked positive-feedback loops to control autoregulation dynamically and provides mechanistic insi

121 nvironment, we have studied the key positive autoregulation element by which the lux QS system integr

122 on of critical processes, including cerebral autoregulation, endothelial-mediated signaling, and neur

123 In regard to dynamic cerebral autoregulation, endotoxemia was associated with lower mi

124 ery mean flow velocity, and dynamic cerebral autoregulation evaluated by transfer function analysis i

125 CO2, and metabolic responses yields the best autoregulation (factor of 1.10).

126 Individualized autoregulation-guided cerebral perfusion pressure manage

127 he methods have focused on identifying "one" autoregulation-guided cerebral perfusion pressure target

128 e randomized research will help define which autoregulation-guided method is beneficial, safe, and mo

129 We found that autoregulation has no effect on the steady-state output

130 The most basic motif, autoregulation, has been associated with bistability (wh

131 d intracranial pressure or impaired cerebral autoregulation have been described as well.

132 ding depolarisations and failure of cerebral autoregulation, have all been implicated in the pathophy

133 response similarly in all genotypes, leaving autoregulation impaired in transgenic animals.

134 (SNP), may equally improve CBF and cerebral autoregulation in a sex dependent manner after FPI.

135 identified a novel mechanism of IGF-IR gene autoregulation in breast cancer cells.

136 by constraints on the evolution of negative autoregulation in diploids.

137 Positive autoregulation in gene regulation networks has been show

138 ebral perfusion and improve dynamic cerebral autoregulation in healthy subjects exposed to endotoxemi

139 (5a) and Pax2 could not replace Pax6 for its autoregulation in lens induction or for neural different

140 y have focused on the importance of cerebral autoregulation in maintaining perfusion, which necessita

141 ificantly improved impaired retinal vascular autoregulation in normal tension glaucoma patients, but

142 ing progressive worsening of cerebrovascular autoregulation in one patient (Pearson coefficient 0.04,

143 rent bacterial genera and is involved in its autoregulation in S. Typhimurium.

144 the importance of miRNA-mediated viral gene autoregulation in some polyomavirus life cycles.

145 Nevertheless, TRA-F stimulation of Sxl autoregulation in the gonadal soma also appears to have

146 ses support the importance of miRNA-mediated autoregulation in the life cycles of some divergent poly

147 nd CNS sensory neurons, establish a role for autoregulation in the maintenance of Barhl1 expression,

148 By contrast, in placental mammals, Nkx2.5 autoregulation in the SHF functions indirectly through M

149 Thus, by disrupting FGF2 autoregulation in vascular ECs, L5 may impair reendothel

150 erate synergistically to amplify Neurogenin3 autoregulation in vitro.

151 eTwist activates its own expression further (autoregulation) in differentiated cells derived from the

152 ity and robustness positively correlate with autoregulation; in all investigated scenarios, stable ne

153 ation reactivity index was the only cerebral autoregulation index predictor of Glasgow Outcome Scale.

154 on z score analysis, the best three cerebral autoregulation index predictors of mortality or Glasgow

155 ation reactivity index was the only cerebral autoregulation index that predicted patient outcome meas

156 at assessed the association between cerebral autoregulation indices and dichotomized or continuous ou

157 Thirty-three studies compared cerebral autoregulation indices and patient outcomes using standa

158 to assess the relationship between cerebral autoregulation indices and predictors of outcome (standa

159 To compare cerebral autoregulation indices as predictors of patient outcome

160 Three cerebral autoregulation indices, pressure reactivity index, mean

161 This autoregulation influences the temporal and/or spatial lo

162 rthermore, in addition to decreasing Neurog3 autoregulation, inhibition of Foxa2 by RNA interference

163 her, our results indicate that RhaS negative autoregulation involves RhaS competition with RhaR for b

164 In addition, we show that the mechanism of autoregulation involves ubiquitin binding by a C-termina

165 Further, CARD-mediated autoregulation is also necessary to maximally suppress c

166 Positive autoregulation is an effective mechanism for the long-te

167 Importantly, Cth2 autoregulation is critical for the appropriate recovery

168 However, cerebral autoregulation is explicitly non-linear and most prior w

169 tion at all doses, whereas with other agents autoregulation is impaired in a dose-related manner.

170 nd mouse, we have found evidence that Nkx2.5 autoregulation is important for maintaining Nkx2.5 expre

171 In this study, we report that BCL6 autoregulation is independent of several known corepress

172 the low and high frequencies, while dynamic autoregulation is likely to be dominant at the very low

173 The model predicts that even when autoregulation is manifest across a range of stimulus le

174 egulates its own expression and that ERalpha autoregulation is most likely absent.

175 However, positive autoregulation is often mediated by signal molecules, wh

176 A model for PknK autoregulation is proposed and discussed.

177 However, negative autoregulation is rare amongst the transcription factors

178 Localized control of tissue blood flow, or autoregulation, is a key factor in regulating tissue per

179 e flow velocity indicating impaired coronary autoregulation, is associated with a significant increas

180 at a unique corepressor requirement for BCL6 autoregulation may allow GC B cells to differentially co

181 Autoregulation may be a commonly used mechanism to contr

182 Homeostatic autoregulation may be a general mechanism to precisely c

183 a comprehensive insight about physiology of autoregulation, measurement methodologies and clinical a

184 Transcranial Doppler based static autoregulation measurements appears to be the most robus

185 A central autoregulation mechanism observed in this unit is functi

186 esistances are controlled via the whole-body autoregulation mechanism.

187 the Wg-dependent feed-forward circuit of vg autoregulation mediated by the QE.

188 Intraoperative cerebral autoregulation monitoring is an important consideration

189 applicable to other signal-mediated positive autoregulation networks as well.

190 Measures of autoregulation obtained from standard laser-Doppler flow

191 of Nus factor genes suggests that Nus factor autoregulation occurs in many bacterial species.

192 ndogenous Caz levels, demonstrating that FUS autoregulation occurs in motor neurons in vivo.

193 cupancy of Qp is equivalent, suggesting that autoregulation occurs, albeit to different degrees, duri

194 Repression of the autoregulation of a TF family by its only splice variant

195 , primer transfer to Polalpha, and concerted autoregulation of alternate activation/inhibition of the

196 al pressure, is critically important for the autoregulation of blood flow.

197 perimental evidence supporting this putative autoregulation of BosR has been lacking.

198 nositol is an important cellular osmolyte in autoregulation of cell volume and fluid balance, particu

199 Apparently, regulation by Mg(2+) and the autoregulation of covR are not linked.

200 umans suggests a conserved mechanism for the autoregulation of CSB/ERCC6 despite the otherwise highly

201 Autoregulation of denitrosylation thus allows cells to s

202 ed disease and provides new insight into the autoregulation of DIAPH1 activity.

203 naling and the regulation of CME, leading to autoregulation of endocytosis and signaling downstream o

204 e in the Brat-mediated system, revealing how autoregulation of GSC number can arise from Brat couplin

205 tory peptide in GTPCH may also contribute to autoregulation of GTPCH activity, but mechanisms are und

206 Here we show that autoregulation of Hsmar1 operates during assembly of the

207 We describe here a novel mechanism of autoregulation of IGF-IR gene expression by cellular IGF

208 of Doa10, MARCH6 (TEB4), by analyzing MARCH6 autoregulation of its own degradation.

209 IL-13Ralpha2 expression, overcoming IL-13's autoregulation of its pathway and enhancing the expressi

210 This discovery of autoregulation of let-7 biogenesis establishes a new mec

211 e show that, due to stochastic fluctuations, autoregulation of mec-3 is not sufficient for TRN differ

212 mooth muscle contraction and participates in autoregulation of mucociliary transport.

213 in the pipette Na(+) concentration, showing autoregulation of Na(+) in beating cardiomyocytes.

214 The autoregulation of NEGAN might be a critical property to

215 Local Ang II signaling may thus allow for autoregulation of neurovascular activity.

216 ion of lateral root development and systemic autoregulation of nodulation (AON) integrated with nitro

217 of the shoot apical meristem, is involved in autoregulation of nodulation (AON), a mechanism that sys

218 Autoregulation of nodulation (AON), a systemic signaling

219 developmental processes in plants, including autoregulation of nodulation (AON), which allows legumes

220 increased expression of early nodulation and autoregulation of nodulation genes, and improved nodulat

221 indicates that SUNN, required for N-mediated autoregulation of nodulation, is not involved.

222 ilS's phosphatase motif was required for the autoregulation of pilA transcription, suggesting that un

223 S that disrupted their interaction prevented autoregulation of pilA transcription.

224 ions in the vasculature, participates in the autoregulation of renal blood flow (RBF), but the underl

225 mice, suggesting that Cav-1 plays a role in autoregulation of resistance vessels in the retina.

226 promoter activity, suggesting RhaS negative autoregulation of rhaSR.

227 Here, we report the mechanism of the autoregulation of Rhp26, which is the homolog of CSB/ERC

228 e-1/186 and rne-1/187), while mRNA decay and autoregulation of RNase E protein levels remained as def

229 Autoregulation of signaling correlated with TGFbeta rece

230 nd characterize signaling pathways mediating autoregulation of stepwise overexpression of nAChR subty

231 nd characterize signaling pathways mediating autoregulation of stepwise overexpression of nAChR subty

232 f AS of the exonized 5S rRNA in quantitative autoregulation of TFIIIA homeostasis.

233 cacies, suggesting the following sequence of autoregulation of the expression of nAChR subtypes: alph

234 cacies, suggesting the following sequence of autoregulation of the expression of nAChR subtypes: alph

235 esponse, and this interaction along with the autoregulation of the immune response by several mechani

236 STAT5a (caSTAT5a) inhibited LEF-1-dependent autoregulation of the LEF-1 gene promoter by binding to

237 and beta-catenin on the Mitf-D enhancer and autoregulation of the Mitf-D and Otx2T0 enhancers.

238 idespread gene repression including feedback autoregulation of the MYC gene itself.

239 found that positive feedback resulting from autoregulation of the native spo0A promoter leads to rob

240 an important role in maintaining the normal autoregulation of the ONH, and it became deficient in th

241 that the ETC6 B-box sequence is involved in autoregulation of the TFC6 promoter.

242 ns, which are thought to arise from negative autoregulation of these genes.

243 s assembly partner but, rather, undergoes an autoregulation of translation.

244 lation-deficient mutant line, altered in the autoregulation-of-nodulation receptor kinase GmNARK, det

245 Split-root and grafting studies using an autoregulation-of-nodulation-deficient mutant line, alte

246 of transcriptional and post-transcriptional autoregulation on fluctuations in protein expression in

247 We examined the effect of positive autoregulation on the steady-state behavior of the PhoQ/

248 al perfusion pressure, and impaired cerebral autoregulation over the entire monitoring period were ca

249 vels consistent with normal retinal vascular autoregulation (P < .0001).

250 decrease) (P < 0.05) coinciding with loss of autoregulation (Pearson coefficient 0.19 --> 0.32, P < 0

251 Continuous assessment of cerebral autoregulation predicted outcome better than intermitten

252 The autoregulation pressure range for control and elevated l

253 evated, the model predicts a decrease in the autoregulation range toward low perfusion pressure, whic

254 igated whether a cerebral perfusion pressure autoregulation range-which uses a continuous estimation

255 ex based on cerebral perfusion pressure, and autoregulation reactivity index (z scores: 8.97, 6.01, 3

256 For patients with subarachnoid hemorrhage, autoregulation reactivity index was the only cerebral au

257 For patients with subarachnoid hemorrhage, autoregulation reactivity index was the only cerebral au

258 ex based on cerebral perfusion pressure, and autoregulation reactivity index were the best outcome pr

259 This pattern indicates disturbed autoregulation, regional perfusion pressure gradients, o

260 rial blood pressure below the lower limit of autoregulation (relative risk 1.02; 95% confidence inter

261 volution of RNA translation and protein-mRNA autoregulation remains an open area of research.

262 d flow but its influence on dynamic cerebral autoregulation remains unknown.

263 on of cholinergic vasodilatation to cerebral autoregulation remains unknown.

264 We found that RhaS autoregulation required the cyclic AMP receptor protein

265 In Drosophila neurons, Nwk autoregulation restricts SH3a domain-dependent synaptopo

266 ase-repression of a transcriptional positive autoregulation (RPAR) loop is critical for shutting down

267 ween dynamic (dCA) and steady-state cerebral autoregulation (sCA).

268 nt progress has been made include aspects of autoregulation, signal integration in branched pathways,

269 vides evidence for a mode of gene expression autoregulation specific to the X chromosome.

270 We propose that Nodal autoregulation substantially aided by rapid ligand trans

271 with brimonidine underwent retinal vascular autoregulation testing and visual function assessment us

272 inputs define a feed-forward mechanism of vg autoregulation that initiates in D-V border cells and pr

273 nzyme grounded in a dynamic understanding of autoregulation that is consistent with a wealth of bioch

274 hypoxic vasodilation that governs blood flow autoregulation, the classic physiological mechanism that

275 several recent studies have focused on gene autoregulation, the effects of negative feedback (NF) on

276 h mean arterial blood pressure was below the autoregulation threshold (mm Hg x min/hr of cardiopulmon

277 ntrol Ptf1a levels, one modulating levels by autoregulation through the PTF1-J complex, and the other

278 Plk4 autoregulation thus guards against genome instability by

279 ent mice (Cx40-ko) had impaired steady-state autoregulation to a sudden step increase in renal perfus

280 n occurs at a variety of levels ranging from autoregulation to ligand and cofactor interactions and p

281 ructed a "linearizer" circuit by adding TetR autoregulation to our original cascade and observed a ma

282 that they have a similar dearth of negative autoregulation to that seen in S. cerevisiae.

283 The lower limit of cerebral autoregulation varied substantially (mean 74.1 mmHg, SD

284 o the phoPQ promoter thereby activating phoP autoregulation via a positive feedback mechanism.

285 Ca(V)1.2 channels also undergo negative autoregulation via Ca(2+)-dependent inactivation (CDI),

286 An identifiable lower limit of autoregulation was ascertained in 348 patients.

287 Autoregulation was characterized via a robust non-linear

288 Autoregulation was intact during hypertension in all gro

289 The status of cerebrovascular autoregulation was monitored as a correlation between bl

290 Autoregulation was monitored during cardiopulmonary bypa

291 We showed that transcriptional autoregulation was more successful than post-transcripti

292 Notably, this autoregulation was necessary for the locomotor response.

293 is prediction, amplification associated with autoregulation was observed in growth-limiting levels of

294 Investigating the mechanisms behind this autoregulation, we found that AP-1 transcription factors

295 O2, hematocrit, sedation, fever,and impaired autoregulation were examined).

296 T and N16D, that independently abolished Rns autoregulation were isolated.

297 lators, and decreases in blood pressure (CBF autoregulation) were similarly reduced in TgNotch3(R169C

298 underlying factor would be impaired vascular autoregulation, which may lead to poor perfusion in OAG.

299 kely that enhanced study of hemodynamics and autoregulation will elucidate both new prevention opport

300 lating the positive feedback associated with autoregulation within a bacterial signaling circuit to b