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1 ether and that the domain interaction can be autoregulatory.
2 eyond ribosomal RNA, and that they are often autoregulatory.
4 ulatory network we study is that of a single autoregulatory activator gene, and the two copies of the
6 wn renders some PyVs more susceptible to the autoregulatory activities of the miRNA, restoring miRNA
7 orb regulatory targets is orb mRNA, and this autoregulatory activity is critical for ensuring that Or
8 that simultaneous loss of both Sox15 and the autoregulatory activity of Su(H) reveals an important ro
10 repertoires (targetomes) while their direct autoregulatory activity on virus-encoded early gene prod
12 duced in the mutant, indicating that AoxR is autoregulatory and at least partially controls the expre
13 h other's transcripts to create a network of autoregulatory and cross-regulatory feedback controls.
17 as the set of promoters for each TF itself (autoregulatory) and the immediately upstream and downstr
18 dback loop illustrates an unexpected mode of autoregulatory behavior of a transcription factor, is co
19 to sensory cell production involves distinct autoregulatory behaviors of Ngn1 (negative) and Math1 (p
20 at residue 2, specifically R2G, disrupt the autoregulatory capability of the wild-type beta-tubulin
21 uctural and functional changes that decrease autoregulatory capacity and increase susceptibility to a
23 In vivo trafficking analysis revealed that autoregulatory CD8 T cells are dependent on neuroinflamm
25 nces, pMHC-nanoparticle-induced expansion of autoregulatory CD8(+) T cells can effectively suppress t
29 ion cells is physiologically associated with autoregulatory changes of the neural-vascular system.
31 ndings identify a novel Notch-dependent HRT2 autoregulatory circuit coordinating transcriptional regu
33 thway during cardiogenesis and identifies an autoregulatory circuit in which tin limits its own expre
36 brafish larvae, wound repair is driven by an autoregulatory circuit that generates pro-migratory tiss
39 functions as a negative regulator in the orb autoregulatory circuit, downregulating orb mRNA translat
42 The Csr system of E. coli contains extensive autoregulatory circuitry, which governs the expression a
44 s generate daily rhythms via cell-autonomous autoregulatory clock gene networks, and, thus, to locali
45 gion structure, suggesting that this mode of autoregulatory control is conserved among higher metazoa
46 arinic m2 receptors (M2Rs) are implicated in autoregulatory control of cholinergic output neurons loc
49 rm to assess the integrity of cardiovascular autoregulatory control systems for risk assessment in he
50 a stable and coherent oscillatory dynamic of autoregulatory control via respiratory entrainment of th
51 mediated via the induction of a long-lasting autoregulatory cycle by which GDNF positively regulates
52 reductase-thioredoxin system, generating an autoregulatory cycle that persists until the thiol-deple
57 binds actin monomers through its diaphanous autoregulatory domain (DAD) that resembles a Wiskott-Ald
61 endent localization and cleavage, C-terminal autoregulatory domain and regulation by an upstream open
62 ctivation is disruption of the juxtamembrane autoregulatory domain by internal tandem duplications (I
63 binding site ("T-site"), thereby keeping the autoregulatory domain displaced and enabling Ca2+/CaM-in
67 ting the interaction between the DID and DAD autoregulatory domains, which releases the FH2 domain to
70 or their abilities to bind predicted AT-rich autoregulatory element (ARE) boxes within the sabRAS reg
71 e HOXA10 estrogen response element (ERE) and autoregulatory element (ARE) were tested for BPA respons
74 egl-5 in the P12.pa cell is influenced by an autoregulatory element that is essential in wild type, b
75 It has been shown recently that the main autoregulatory elements of PDZRhoGEF, the autoinhibitory
76 like their eukaryotic counterparts, possess autoregulatory elements that influence how hexameric mot
81 gesting a mechanism for priming the 3' Atoh1 autoregulatory enhancer needed for hair cell expression.
82 domain is complemented by an adjacent 2.3-kb autoregulatory enhancer that is able to activate a heter
85 ranscriptional regulator, deformed epidermal autoregulatory factor 1 (Deaf1), that can regulate PTA e
87 widely deployed in cell lineages, where the autoregulatory factor controls the activity of a battery
88 cade is inhibited by farnesol, a C. albicans autoregulatory factor, and small molecules such as dodec
89 tional regulatory factor, deformed epidermal autoregulatory factor-1 (DEAF-1), also contributes to th
90 ated to atrophy, inflammation, or changes in autoregulatory factors or growth factors remains to be d
91 delayed ischemic deficits due to vasospasm, autoregulatory failure, and intravascular volume contrac
93 e metabolism of FICZ, thereby disrupting the autoregulatory feedback control of cytochrome P4501 syst
96 ere, we show the existence of a proapoptotic autoregulatory feedback loop between p73, YAP, and the p
98 nism for genetic disease by disruption of an autoregulatory feedback loop critical for maintenance of
100 ings suggest the presence of a c-Myb-miR-15a autoregulatory feedback loop of potential importance in
101 hormone target and is involved in a positive autoregulatory feedback loop that modulates thyroid horm
102 ere we show that a hippocampal BDNF-positive autoregulatory feedback loop via CCAAT-enhancer binding
103 rmal cells p53 levels are kept low due to an autoregulatory feedback loop where p53 activates the tra
105 ic marks, along with its participation in an autoregulatory feedback loop with genes known to transfo
106 to its own promoter, defining a new negative autoregulatory feedback loop within the core clock.
113 e cell and a number of positive and negative autoregulatory feedback loops act upon the p53 response.
114 ostatic hypotheses by explicitly emphasizing autoregulatory feedback loops and known synaptic biology
117 transcription in SLE T cells, we propose an autoregulatory feedback mechanism between CREM and AP-1.
118 irst miRNA that monitors c-Myc levels via an autoregulatory feedback mechanism in response to serum s
119 The present studies thus unveil a novel autoregulatory feedback mechanism that negatively contro
121 gth viral genome, this mechanism promotes an autoregulatory feedback that decreases expression of tat
123 and C-terminal domains of SPN, suggesting an autoregulatory function similar to that of importin-alph
128 s that express key elements of the circadian autoregulatory gene network and that the inner nuclear a
129 very of viral master circuits: virus-encoded autoregulatory gene networks that autonomously control v
132 Our findings establish the DnaB collar as an autoregulatory hub that controls the ability of the heli
133 rives monocyte proinflammatory processes and autoregulatory IL-10 in a serum IgE-dependent manner.
135 nsfer function analysis (gain and phase) and autoregulatory index (ARI) fit from spontaneous oscillat
136 blood flow, cerebral perfusion pressure, and autoregulatory index decreased markedly during hypotensi
137 NP did not prevent reductions in CBF, CPP or autoregulatory index during combined hypotension and FPI
138 blood flow, cerebral perfusion pressure, and autoregulatory index during hypotension in females but i
139 artery diameter, intracranial pressure, and autoregulatory index were determined before and after fl
140 and cerebral autoregulation, defined by the autoregulatory index, at 6 and 36 hrs; 2) continuous mon
141 ndividuals in all (steady-state and dynamic) autoregulatory indices, ranging from low (almost absent)
142 s, thereby demonstrating the conservation of autoregulatory infrastructure across the IpaH enzyme fam
143 es provided evidence for crossregulatory and autoregulatory interactions among components of this com
144 ong with controlling membrane binding, these autoregulatory interactions inhibit the ability of Nwk-S
146 by eIF2alpha phosphorylation destabilizes an autoregulatory intramolecular interaction within eIF2alp
148 HAT assays suggest that the RING domain, the autoregulatory loop (AL) within the HAT domain, and the
149 d middle meiotic promoter through a positive autoregulatory loop and is repressed in vegetative cells
152 demonstrate the presence of a novel feedback autoregulatory loop between INrf2 and Nrf2 that controls
153 port a previously unrecognized bidirectional autoregulatory loop between MTA1 and tumor suppressor al
156 these mechanisms Blimp-1 participates in an autoregulatory loop by which IL-2 induces Prdm1 expressi
159 d that Ntl functions normally to protect the autoregulatory loop from endogenous RA by directly activ
160 A conserved transcriptional-translational autoregulatory loop generates molecular oscillations of
162 tes the activity of Spo0A through a positive autoregulatory loop involving KinC, a histidine kinase t
163 ory circuitry of ES cells, which includes an autoregulatory loop involving the pluripotency regulator
165 newly identified control should result in an autoregulatory loop limiting the amount of OmrA/B sRNAs.
167 e NDRs, established by OCT4, in ensuring the autoregulatory loop of pluripotency and, furthermore, th
168 occupancy of the Etv1 gene itself, and this autoregulatory loop preceded ETV1 binding and activation
169 that SHH and Atoh1 contribute to a positive autoregulatory loop promoting neuronal precursor expansi
171 CL6 gene alterations is to bypass a negative autoregulatory loop that controls its transcription.
172 and revealed a novel STARS-SRF feed-forward autoregulatory loop that could play an essential role in
173 emonstrate that Greatwall participates in an autoregulatory loop that generates and maintains suffici
174 factors OCT4, NANOG and SOX2 form a positive autoregulatory loop that is pivotal for maintaining the
175 A2 and 1B1, thereby also participating in an autoregulatory loop that keeps its own steady-state conc
176 ating that these proteins may function in an autoregulatory loop that maintains appropriate levels of
177 which interacts functionally with MDM2 in an autoregulatory loop that parallels the p53/MDM2 feedback
178 ase, in part through the up-regulation of an autoregulatory loop that promotes podosome formation.
179 r cells, the enhancer and PTF1a establish an autoregulatory loop that reinforces and maintains Ptf1a
180 ion, whereas ER71 and SOX9 participate in an autoregulatory loop to sustain each other's expression a
181 y interfering with IL-13's negative feedback autoregulatory loop under MEK/ERK-dependent conditions.
182 tudy, we characterize a Neurogenin3 positive autoregulatory loop whereby this factor may rapidly indu
183 dence that CEH-17 participates in a positive autoregulatory loop with CEH-14 in ALA, and that CEH-10,
184 ow that TAL1 forms a positive interconnected autoregulatory loop with GATA3 and RUNX1 and that the TA
185 vertebrate embryo depends on a Brachyury/Wnt autoregulatory loop within the posterior mesodermal prog
186 Together, we identified a novel p53-RNPC1 autoregulatory loop, and our findings suggest that RNPC1
187 t the BDNF gene is a subject to an extensive autoregulatory loop, where TrkB signaling upregulates th
188 hese data imply that PSMA participates in an autoregulatory loop, wherein active PSMA facilitates int
197 eam targets, and that a number of unexpected autoregulatory loops exist between Sox17 and Gata4-6, be
200 Indeed, the trimeric PTF1 complex forms dual autoregulatory loops with the Ptf1a and Rbpjl genes that
203 resynaptic receptors on POMC terminals in an autoregulatory manner to limit continued transmission.
204 otubule motor-cargo interface and associated autoregulatory mechanism can be manipulated using a smal
205 KE 1 (DCL1), suggesting a second homeostatic autoregulatory mechanism for DCL1 expression; another de
206 first to implicate ligand dimerization as an autoregulatory mechanism for growth factor bioactivity a
211 A1 represent a p53-independent bidirectional autoregulatory mechanism in which these two opposites ac
213 omes of opioid drugs, which suggests that an autoregulatory mechanism may function in opioid systems.
214 is critically dependent on a self-sustaining autoregulatory mechanism mediated by the Pit-1 protein.
219 eptide products and reveal clues for a novel autoregulatory mechanism that might have significant imp
221 report that Nanog is subjected to a negative autoregulatory mechanism, i.e., autorepression, in ESCs,
227 on of individual proteins correlate to known autoregulatory mechanisms and extend the network of ribo
229 osomal protein genes are often controlled by autoregulatory mechanisms in which a protein encoded in
233 neurons in mice relies on a transcriptional autoregulatory module initiated via transient activity o
234 aB in a novel feed-forward, self-amplifying, autoregulatory module regulated by the ERBB family of gr
235 he identification of an 11-mer peptide as an autoregulatory molecule in C. neoformans suggests that a
236 roved that the oligopeptide functioned as an autoregulatory molecule responsible for the density-depe
240 tion is highly conserved in the beta-tubulin autoregulatory MREI (methionine-arginine-glutamic acid-i
241 e that Chtop expression is controlled via an autoregulatory negative feedback loop whereby Chtop bind
242 d supply induces Pten expression creating an autoregulatory negative feedback loop, whereas complete
246 ormed parameter searches to demonstrate that autoregulatory negative-feedback loops of the redundant
252 new role of the TF cytoplasmic domain in an autoregulatory pathway that controls LPS-induced TF expr
256 osophila circadian oscillator is composed of autoregulatory period/timeless (per/tim) and Clock (Clk)
257 teins reflects the operation of an adaptive, autoregulatory process of functionally significant aggre
258 then by creating an environment in which an autoregulatory process restricts the immune response to
260 ogene and that Erk molecules possess unusual autoregulatory properties, some of them independent of T
262 and vceR, which codes for a transcriptional autoregulatory protein that negatively regulates the exp
264 se domains of the constitutive isoforms, the autoregulatory region (AR) and the C-terminal tail regio
268 -resolved OCT angiography to investigate the autoregulatory response in the 3 parafoveal retinal plex
269 ngiography was able to show that the retinal autoregulatory response to hyperoxia affects only the de
272 ectively, these findings indicate a positive autoregulatory role for INSL3 signaling in maintaining t
273 ion of POMC neurons such that attributing an autoregulatory role to opioids must include consideratio
275 tors and demonstrates an unexpected level of autoregulatory scaffolding in mammalian stress-activated
276 re dedicated protein kinases regulated by an autoregulatory segment C terminus of the catalytic core
279 S. acidiscabies, a gene cluster encoding GBL autoregulatory signaling homologs was identified and cha
280 ce DUSP1 mRNA expression, suggesting that an autoregulatory signaling loop may be activated by Stxs.
282 lector gene engrailed is silenced through an autoregulatory silencing mechanism that requires the PRC
283 omal rearrangements, mutations of a negative autoregulatory site in the BCL6 promoter region and aber
284 0 vs. 3.7 +/- 0.8 mmHg) while increasing the autoregulatory slope (0.10 +/- 0.05 vs. 0.24 +/- 0.08 cm
286 , trauma severity, intracranial pressure, or autoregulatory status, and thus represent a discrete phe
287 reventing cachexia, we developed a molecular autoregulatory system involving a single recombinant ade
293 d organismal physiology are controlled by an autoregulatory transcription-translation feedback loop t
295 e circadian clock in mammals is driven by an autoregulatory transcriptional feedback mechanism that t
296 ically integrated circuits that use bistable autoregulatory transcriptional feedback to retain memory
299 as selective removal of I-E on DCs abrogated autoregulatory Treg formation and T1D protection, select
300 cy is established when the expression of the autoregulatory viral trans-activating factor Tat is redu
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