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1 , median of 1.5 to 2.1 vs. 1.8 to 2.6 deaths averted).
2 panying improvements to care ($1760 per DALY averted).
3 probably be cost-effective (US$571 per DALY averted).
4 by far the largest contributor (68% of cases averted).
5 n of HIV infections at US$2960 per infection averted.
6 e total number of heavy infection case-years averted.
7 esulted in substantial cost savings from OIs averted.
8 monstrate that these cells are also a crisis averted.
9 lse-positive results to breast cancer deaths averted.
10 CER for HIV-negative women was $6.2 per DALY averted.
11 ars per disability-adjusted life-year (DALY) averted.
12 timated incremental cost per self-harm event averted.
13 me measure was the incremental cost per DALY averted.
14 nd the number of hospitalizations and deaths averted.
15 effectiveness ratio (ICER) of $7.28 per DALY averted.
16 tional 161,560 cardiovascular disease events averted.
17 (290-424) per disability-adjusted life-year averted.
18 lier, a further 12,500 cases could have been averted.
19 874 (434 902-4 740 724) per HIV transmission averted.
20 DS targets, with 38% (26%-51%) of infections averted.
21 h the Xpert Ultra cartridge was projected to avert 0.5 TB deaths (95% uncertainty range [UR]: 0, 1.3)
22 h heterogeneously or extremely dense breasts averted 0.36 additional breast cancer deaths (range acro
23 nd more effective in terms of adverse events averted (0.9989 vs 0.9957 and 0.9947, respectively).
27 decolonization was the dominant strategy; it averted 1.31% and 1.59% of methicillin-resistant Staphyl
28 and on-ART) would have a much larger impact, averting 1.10 million disability-adjusted life-years (DA
29 income countries to very low levels, thereby averting 10 million deaths per year from 2035 onward.
30 delivery of IPTp-SP3+ to 1000 pregnant women averted 113.4 DALYs at an incremental cost of $825.67 pr
31 decade, application of CDC guidelines would avert 1162 infections per 100 000 person-years, 33.0% of
32 cally immediately achieve 90% coverage would avert 149 000 maternal deaths, 849 000 stillbirths, 1 49
33 0 and $870 more per woman, respectively, and averted 15 and 16 deaths per 1000 women at high risk for
34 t elimination of sexual violence alone could avert 17% of HIV infections in Kenya (95% uncertainty in
35 ropogenic organic aerosol is responsible for averting 180,000 (117,000-389,000) premature deaths betw
36 002 000 life-years; over 10 years, it would avert 2 051 000 HIV transmissions, 2 478 000 deaths, and
37 coordinated approaches were highly similar, averting 2,976 and 2,789 CRE transmission events, respec
38 st coverage of sex worker-led outreach could avert 20% (95% UI 8-36) of infections in the next decade
39 lung cancer risk (>/=1.9%) was estimated to avert 20% more deaths (55,717 [95% CI, 53,033-58,400]) a
40 ategy, the BTT strategy would be expected to avert 24.4-30.5% more complications and be more cost-eff
41 on HIV/AIDS 95-95-95 target was estimated to avert 25 million [20M, 33M] of these new infections, and
42 cost saving ( pound1.0 billion discounted), avert 25% of HIV infections (42% of which would be direc
43 PrEP+screen+ART dominates other strategies, averting 26 700 infections and reducing HIV prevalence a
44 mpared with Current Pace over 20 years, NHAS averted 280000 HIV transmissions (80000 in black MSM) an
46 course of HIV epidemics across all settings, averting 33-46% of HIV infections in the next decade.
47 l count of less than 500 cells per muL could avert 34% (95% UI 25-42) of infections and even modest c
48 resulted in a small number of cancer deaths averted (39 of 100 000 men, 38 of 100 000 women) and a n
50 vention along present funding channels could avert 5.3 million infections relative to no scale-up.
51 Reaching the UNAIDS targets on time would avert 50% (42%-60%) of new HIV infections over 2015-2030
54 -effectiveness ratio (ICER) of $540 per DALY averted, $645 per life-year saved, and $511 per QALY gai
55 , median of 3.4 to 5.1 vs. 4.1 to 6.5 deaths averted; 65 to 74 years, median of 1.5 to 2.1 vs. 1.8 to
59 ver 5 years the UNAIDS target strategy would avert 873 000 HIV transmissions, 1 174 000 deaths, and 7
61 , at 372 unnecessary treatments per TB death averted (95% UR: 75, indefinite upper bound), although t
62 m distribution, and male circumcision, could avert a further 150 000 new infections, save 5000 lives,
63 d, PMI-funded interventions are estimated to avert a further 162 million (95% CrI: 116 million, 194 m
66 PR2-10 of 10-65%, RTS,S/AS01 is predicted to avert a median of 93,940 (range 20,490-126,540) clinical
68 but not in the rest of the population) would avert a similar fraction of new infections (30%; 21%-39%
69 ely 35,000 to 60,500 additional ventilators, averting a pandemic total 178,000 to 308,000 deaths.
70 l 7000 to 11,000 ventilators will be needed, averting a pandemic total of 35,000 to 55,000 deaths.
71 s renal oxygen sensing could act as a brake, averting a potentially detrimental fall in hematocrit.
72 ision of essential surgical procedures would avert about 1.5 million deaths a year, or 6-7% of all av
73 70% of the countywide cases of MRSA carriage averted after 1 year of universal ICU decolonization wer
74 xt 35 years, the expansion of treatment will avert an additional 3.8 million new infections, save 1.1
76 ibution of filters and bottled water) likely averted an even worse exposure event due to rising water
77 ions of $30 (range 18-211) per clinical case averted and $80 (44-279) per DALY averted for the three-
79 g several outcome measures, including deaths averted and program cost over a 5-year period; lifetime
80 h test's purpose (for example, transmissions averted) and comparing systems with the test against tho
81 analysis to assess the health gains (deaths averted) and financial risk protection afforded (cases o
82 effects (ie, disability-adjusted life-years averted) and resource implications for 2016-35, includin
83 nly school-aged children (ICER $167 per DALY averted) and WHO guidelines (ICER $127 per DALY averted)
84 rted) and WHO guidelines (ICER $127 per DALY averted), and remained highly cost effective even if tre
85 h, $14,783 (12,389-17,960) per new infection averted, and $351 (290-424) per disability-adjusted life
86 t effectiveness threshold of US$500 per DALY averted, and discounted DALYs and costs at 3% per year.
87 , pound372 207 (268 162-1 903 385) per death averted, and pound628 874 (434 902-4 740 724) per HIV tr
88 domestic product per capita ($487) per DALY averted, and remain robust over a wide range of epidemio
89 generated, the projected number of TB deaths averted, and the projected number of unnecessary treatme
90 tal number of prevalent infection case-years averted, and the total number of heavy infection case-ye
91 al dollars per disability-adjusted life year averted, and was consistently preferred to TIV-based pol
94 >/= 10% used similar financial resources but averted approximately 5 million more disability-adjusted
95 gs in healthcare costs of $75 million, while averting around 7000 disability-adjusted life-years over
96 an delivery in countries with low CDRs could avert as many as 163 513 maternal deaths and 803 129 neo
97 ed the model to estimate how many cases were averted as a result of the introduction of additional tr
98 roles of these peripheral Tregs (pTregs) in averting autoimmune responses, as well as immunological
100 lf-antigens and persisting foreign antigens, averting autoimmunity and immune pathogenesis, but allow
101 ed the intervention's cost per ETU admission averted (average cost-effectiveness ratio) by season (we
102 rfaces that actively elute antimicrobials to avert bacterial adhesion and promote killing; and 3) sur
103 zoles with a free N-H bond, isomerization is averted because the heterocycle is deprotonated in situ.
107 atic, AAV9-mediated repletion of the protein averts brain microvasculature defects and prevents disea
109 forward), (ii) indirect gaze (head and eyes averted by 20 degrees ), or (iii) direct-oblique gaze (h
111 er of disability-adjusted life years (DALYs) averted by a hydrocelectomy and identified the cost thre
112 f triplex-induced genomic instability may be averted by activating apoptosis via dual phosphorylation
115 n of proliferation of polyploid cells can be averted by increased levels of oncogenes such as cyclin
116 cule but is toxic at high concentrations, is averted by its efficient oxidation by the mitochondrial
117 ars incurred by surgical conditions could be averted by providing access to timely and safe surgery i
118 f the global burden of disease that could be averted by surgery and safe anaesthesia might also be re
119 atments added by Ultra per incremental death averted by Ultra compared to outcomes using standard Xpe
120 nnecessary prostate biopsies would have been averted by using the urine assay results to select men f
121 l risk protection afforded (cases of poverty averted) by a bundle of nine (among many other) interven
122 ifts can be detected in advance, and perhaps averted, by monitoring resilience indicators such as var
123 to 30 times that of the general population, averted cancer deaths and life expectancy gains increase
125 Intensive blood pressure (BP) treatment can avert cardiovascular disease (CVD) events but can cause
126 health (85% of the overall study population) averted cardiovascular events from a behavioural interve
127 ated regional control resulted in 21.3% more averted cases (n = 408) than did uncoordinated control a
130 ession ameliorate kidney injury, possibly by averting cell division in the presence of extensive DNA
132 n to improve HPV prevention and subsequently avert cervical and possibly male HPV-related cancers.
133 US dollars), health outcomes (HIV infections averted, change in HIV prevalence, and discounted qualit
134 Outcome Measures: Infections averted, deaths averted, change in HIV prevalence, discounted costs (in
135 Such an approach can potentially help to avert clonal evolution, a major cause of therapeutic res
136 in terms of cost savings and adverse events averted compared with IV argatroban or bivalirudin infus
137 oth these critical safeguards in the RPE and avert complement-induced mitochondrial injury in vitro a
139 to epidemic or endemic regions is needed to avert congenital ZIKV syndrome, and might also help to s
141 ost per disability-adjusted life-year (DALY) averted; cost per life-year saved; and cost per quality-
144 births by almost 28 million and consequently avert deaths that could have occurred at 2015 rates of f
147 ity to dramatically improve human health and avert dire environmental outcomes, and ACP believes that
149 tem cells flow from their origin in the lens-averted domain of the optic vesicle to their destination
150 h usually destroys superconductivity) may be averted due to a screened long-range Coulomb repulsion i
151 re than 79000 suicide attempts may have been averted during the period studied following implementati
153 nio rerio) as a model, we show that the lens-averted epithelium functions as a reservoir that contrib
154 ed ETU-stay costs) and benefits (in terms of averted ETU admissions) in west Africa, from a health-ca
155 irus disease (in terms of administration and averted ETU-stay costs) and benefits (in terms of averte
156 ting to 959 deaths and 5831 hospitalizations averted every year in Mexican children aged <5 years.
157 s with overlapping NIMA specificity, thereby averting fetal wastage triggered by prenatal infection a
159 rate risk of low birthweight, $19.4 per DALY averted for low risk, and $4.0 per DALY averted for high
160 itivity analyses, the ICER was $7.7 per DALY averted for moderate risk of low birthweight, $19.4 per
161 0 hospitalizations and 0-165,000 deaths were averted for programs beginning the same time as or after
162 nical case averted and $80 (44-279) per DALY averted for the three-dose schedule, and of $25 (16-222)
163 e drug-treatment and monitoring costs, costs averted for the treatment of cardiovascular disease, and
165 cymakers in developing adequate responses to avert further losses of biodiversity when population and
168 ers who were exposed to faces with direct or averted gaze under continuous flash suppression, thereby
169 direct gaze elicited greater responses than averted gaze when participants were aware of the faces,
170 ient to give rise to awareness compared with averted gaze, possibly because the human brain is attune
171 ufficient to give rise to awareness than for averted gaze, thus providing a neural basis for privileg
175 differentially affects perception of clear (averted-gaze fear) and ambiguous (direct-gaze fear) faci
176 associated with higher anxiety for M-biased averted-gaze fear, while increased left amygdala reactiv
178 ion in children was estimated to potentially avert >161 000 OIs (2013 UNAIDS data) with estimated cos
181 mbosis, decreased neutrophil activation, and averted histone-induced production of inflammatory cytok
185 t was centred on eastern China was seemingly averted, human infections recurred in October 2013.
186 7.3%) of breast cancers could potentially be averted if all overweight and obese women attained a bod
187 nopausal breast cancers could potentially be averted if all women with heterogeneously or extremely d
188 The number of OI cases and associated costs averted if ART was initiated at a CD4 count >/=200 cells
189 nnecessary treatments generated per TB death averted, if standard Xpert were switched to Xpert Ultra.
190 re delivered via a mobile app can be used to avert in-person follow-up care visits compared with conv
191 n can use follow-up care via a mobile app to avert in-person follow-up visits during the first 30 day
193 and 3700 (2600-4900) new infections could be averted in MSM by 2022, corresponding to a 53% reduction
194 ses were performed, our projections of cases averted in past epidemics are based on severely limited
195 la cases (both reported and unreported) were averted in Sierra Leone up to February 2, 2015 as a dire
196 levels in wild-type mice, hyperglycemia was averted in similarly treated Gcgr(-/-) mice and the plas
200 ver 30 000 cases of IPD and 3000 deaths were averted in the first 3 years after the introduction of P
201 le deaths, a total number of deaths possibly averted in the previous year with access to appropriate
204 ed by released inmates, wherein about 90% of averted infections would have occurred outside of prison
206 rast, HGAL myristoylation and palmitoylation avert its inhibitory effects on chemoattractant-induced
207 preventing GPI anchoring of CaValpha2delta1 averts its cell-surface expression, its interaction with
208 ic mortality reduction, breast cancer deaths averted, life-years, and quality-adjusted life-years); n
211 ver, the superiority of the BTT strategy for averting microvascular complications is contingent on in
213 ion campaigns using a single dose of OCV may avert more cases and deaths than a standard two-dose cam
214 behavioural and metabolic risk factors could avert more than three-quarters of the global stroke burd
215 s), number and percentage of overdose deaths averted, number of HIV-related deaths averted, total cos
216 atest impact at an incremental cost per DALY averted of $5588 when compared with coverage of primary
217 s and cost per disability-adjusted life-year averted of introducing Xpert as the initial diagnostic t
219 rrent U.S. EPA standard, 12 mug m(-3), would avert only ~17% (if C-R is linear: approximately 25%) of
220 t-effective, but any individual intervention averted only a small percentage of deaths because the ef
222 le they viewed fearful or neutral faces with averted or directed gaze, with the luminance and color o
223 >0.53 million disability-adjusted-life-years averted over 2022-2042, with a reduction in HIV program
225 their hospital bills for them), stillbirths averted, palliative care, contraception, and child physi
226 eumococcal conjugate vaccination (170 deaths averted per $100,000 spent), and caesarean section surge
227 000 spent), tuberculosis treatment (96 cases averted per $100,000 spent), and hypertension treatment
228 t deaths are measles vaccination (367 deaths averted per $100,000 spent), pneumococcal conjugate vacc
229 erty are caesarean section surgery (98 cases averted per $100,000 spent), tuberculosis treatment (96
232 er 10 000 discharges were found to have been averted per year in the highest-, average-, low-, and lo
233 by watch and wait avoided major surgery and averted permanent colostomy without loss of oncological
234 sed to estimate the percentage of infections averted (PIA) and the number needed to treat (NNT) under
235 66) per Disability Adjusted Life Year (DALY) averted, PMI-funded interventions are highly cost-effect
238 n-resistant Staphylococcus aureus infections averted, quality-adjusted life years gained, and increme
239 Expressed in relative terms, the proportion averted ranged from 20.8% (95% CI: 16.8, 24.3) of potent
240 seasonal epidemics, the number of infections averted ranged from 9.6 million in the 2006-2007 season
241 e extent to which early outpatient follow-up averts readmission or improves outcomes in cirrhosis is
243 ss of age-specific vaccination strategies in averting RSV incidence, we developed a transmission mode
247 lupeol can act as contraceptive compounds by averting sperm hyperactivation, thus preventing fertiliz
250 Ethiopian Government, the interventions that avert the most deaths are measles vaccination (367 death
253 st be 35%-56% as efficacious as two doses to avert the same number of cases with a fixed amount of va
255 yle intervention (ILI) for weight loss would avert the unfavorable cardiometabolic effects associated
257 otitis media, pneumonia, and septicemia and averted the cytokine storm associated with septic infect
259 ans of reducing the number of taxa affected, averting the ecological impacts of night-time lighting m
260 e overall reaction mechanism responsible for averting the formation of thermodynamically favored side
261 Modified Vaccinia Ankara (MVA) vector, thus averting the potential risk of ADE associated with struc
262 degradation of non-APC/C substrates and also averts the cell-cycle errors and genomic instability tha
266 tic, and there is no targeted therapeutic to avert this proximal event in glomerular inflammation.
268 ate that targeting the CAR to the TRAC locus averts tonic CAR signalling and establishes effective in
269 deaths averted, number of HIV-related deaths averted, total costs (in 2015 US$) associated with each
270 ylation of La promotes cell proliferation by averting ubiquitination-mediated degradation of the STAT
272 ined urinary testing for T2:ERG and PCA3 can avert unnecessary biopsy while retaining robust sensitiv
275 oxygen, pulse oximetry has the potential to avert up to 148,000 deaths if implemented across the 15
276 that, over 20 y, 50% coverage with OAT could avert up to 22,000 (95% CI: 5,200, 46,000) infections an
277 000) per QALY gained, 50% NSP coverage could avert up to 35,000 (95% CI: 8,900, 43,000) infections an
278 per QALY gained, and 50% PrEP coverage could avert up to 37,000 (22,000, 58,000) infections and cost
279 QALY gained, 50% Test & Treat coverage could avert up to 6,700 (95% CI: 1,200, 16,000) infections and
282 und306 000 ($428 000), and the cost per case averted varies from pound500 ($700) to pound61 000 ($85
290 , and disability-adjusted life-years (DALYs) averted were calculated over a 15 year time horizon for
292 nd an RR of 1.0 or 1.3, breast cancer deaths averted were similar for triennial versus biennial scree
293 pitalizations and 11,000-281,000 deaths were averted when campaigns started before a pandemic, and <1
294 al cost-effectiveness ratio of $469 per DALY averted when compared with the status quo of no coverage
295 ls that target conserved epitopes may not be averted when DAA therapy fails prematurely due to emerge
297 t $205 to $272/disability-adjusted life-year averted, which was $142 to $182 less per disability-adju
298 stimated large potential cost savings in OIs averted with ART use, although there are greater uncerta
299 ransmission to simulate costs and disability averted with integrated MDA (of praziquantel and albenda
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