ライフサイエンスコーパス: axonal guidance

1 t a critical role for L1CAM in corticospinal axonal guidance.

2 etermination, male copulatory structures and axonal guidance.

3 e developmental vascular assembly and direct axonal guidance.

4 that physical cues can play crucial role in axonal guidance.

5 P61F and the unidentified phosphoproteins in axonal guidance.

6 s system development and function, including axonal guidance.

7 s such as cell migration, wound healing, and axonal guidance.

8 location to endosomes, AChR localization and axonal guidance.

9 glia and Vim(+) radial glia may aid in early axonal guidance.

10 igodendrocytes and is a critical receptor in axonal guidance.

11 member of the semaphorin family important in axonal guidance.

12 ying critical roles in neuronal survival and axonal guidance.

13 e importance of modifier genes in vertebrate axonal guidance.

14 ograde transport and microtubule function in axonal guidance.

15 e common signaling events in plexin-mediated axonal guidance.

16 r, and semaphorin 3A (Sema3A), a mediator of axonal guidance.

17 family receptors are conserved regulators of axonal guidance.

18 lays a crucial role in Semaphorin3a-mediated axonal guidance.

19 ember of the semaphorin family, important in axonal guidance.

20 2 mediates both precrossing and postcrossing axonal guidance.

21 ins involved in neuronal differentiation and axonal guidance.

22 ludes Dock, an adaptor protein important for axonal guidance.

23 netrin-1, a molecule that may be involved in axonal guidance and cell migration, our results suggest

24 ariety of developmental processes, including axonal guidance and cell migration.

25 eby regulating the actin-cytoskeleton during axonal guidance and cell migration.

26 ith a dual function of the unplugged gene in axonal guidance and cell motility.

27 function seems to be mediated by G proteins, axonal guidance and cell survival may be G protein-indep

28 propose that biological factors relating to axonal guidance and command neuron functions contribute

29 microdevices specifically designed to study axonal guidance and compare them with the conventional a

30 Pa-En2 both contribute toward the control of axonal guidance and confirmed that Pa-En1 has the paralo

31 at consists of growth factor, cell adhesion, axonal guidance and cytoskeletal modifying molecules tha

32 system, where it regulates processes such as axonal guidance and elongation.

33 The cell adhesion molecule L1 regulates axonal guidance and fasciculation during development.

34 he Slits are secreted proteins with roles in axonal guidance and leukocyte migration.

35 molecules L1 and CHL1, which are crucial for axonal guidance and maintenance of neural circuits, for

36 hat the Slit proteins, which are involved in axonal guidance and related developmental processes in n

37 rin receptor expressed in BCs, controls both axonal guidance and subcellular target recognition.

38 ns, suggesting a role for these receptors in axonal guidance and synapse formation during neuronal de

39 mproper pathway activation causes defects in axonal guidance and synaptic growth, whereas loss-of-fun

40 s neuronal migration, cytoskeletal dynamics, axonal guidance and synaptic plasticity among others.

41 Axonal guidance and synaptic specification depends on sp

42 f sexually dimorphic circuits by influencing axonal guidance and synaptogenesis.

43 Axonal guidance and vascular patterning share several gu

44 iferation, cell specification, migration and axonal guidance); and (iv) combined hypoplasia and atrop

45 Semaphorins play an essential role in axonal guidance, and emerging evidence points to diverse

46 gnaling cascades that regulate angiogenesis, axonal guidance, and neuronal plasticity.

47 ellular functions in mammalian cells such as axonal guidance, apoptosis, and chemotaxis.

48 nsitive events such as neurite extension and axonal guidance are driven by Ca(2+) signals that are pr

49 To develop a better understanding of axonal guidance at the molecular level, we purified prot

50 To develop a better understanding of axonal guidance at the molecular level, we used the SH2

51 erse array of physiologic processes, such as axonal guidance, bone remodeling, and immune cell develo

52 tant role of furin in development, including axonal guidance, cardiogenesis, and maintenance of stem

53 nriched for genes involved in cell adhesion, axonal guidance, cell surface receptor expression and ac

54 ns reveals enrichment of genes implicated in axonal guidance, cell-cell adhesion, neuronal morphogene

55 adaptor protein that functions in Drosophila axonal guidance, consists of three tandem Src homology 3

56 tly, the anti-inflammatory properties of the axonal guidance cue netrin-1 were reported.

57 Using live imaging, we demonstrate that the axonal guidance cue Slit and its receptor Robo are both

58 h ephrinB3 being a developmentally important axonal guidance cue whose expression in mature oligodend

59 lapse elicited by Semaphorin 3A (Sema3A), an axonal guidance cue.

60 Axonal guidance cues (AGC) are molecules that guide the

61 are known to act as diffusible and repellant axonal guidance cues during nervous system development.

62 The axonal guidance cues that organize this precise projecti

63 s can dramatically change their responses to axonal guidance cues, but the physiological signals that

64 We utilized antibodies against axonal guidance cues, such as the cell surface glycoprot

65 ng developmental switch in responsiveness to axonal guidance cues.

66 he PFP or the corpus callosum make different axonal guidance decisions in the same anatomical region

67 Remarkably, the axonal guidance defects observed in B3gnt1, ISPD, and dy

68 r movement-like deficits are associated with axonal guidance defects of two identified groups of comm

69 The cell adhesion molecule L1 mediates axonal guidance during neural development and mutations

70 tivation of Plexin (Plex) receptors provides axonal guidance during neuronal development.

71 glion cells, which in turn respond by making axonal guidance errors at the optic chiasm.

72 s play a crucial role in the transduction of axonal guidance events elicited by semaphorin proteins.

73 ma-2b signaling that mediates mechanosensory axonal guidance, fasciculation, and synaptic target sele

74 mily and confirms that both the cellular and axonal guidance functions of C. elegans unc-5 have been

75 s with CasL), but requires MICAL for certain axonal guidance functions.

76 in cell migration, tissue morphogenesis, and axonal guidance in many different systems.

77 l surface and secreted proteins that provide axonal guidance in neuronal tissues and regulate cell mo

78 ays a critical role in neuronal survival and axonal guidance in the developing murine hippocampus and

79 ial for growth, cell fate determination, and axonal guidance in the developing nervous system.

80 ntrol integrins, the actin cytoskeleton, and axonal guidance in the extending neurite.

81 tor Neogenin are thought to be regulators of axonal guidance in the nervous system.

82 ive renewed perspective on the mechanisms of axonal guidance in the spinal cord that provide for a di

83 egulates among others neuronal outgrowth and axonal guidance in vertebrates and invertebrates.

84 Axonal guidance involves extrinsic molecular cues that b

85 eating using micro-heater confirmed that the axonal guidance is caused by shallow temperature-gradien

86 Axonal guidance is key to the formation of neuronal circ

87 inal ganglion cell (RGC) differentiation and axonal guidance is required for a functional visual syst

88 The role of vesicular traffic in axonal guidance is still largely unknown.

89 thway, best known for its role in regulating axonal guidance, is essential for proper gonad formation

90 We propose an axonal guidance model in which different guidance cues a

91 s along the PSPB, as well as to a failure of axonal guidance molecule expression, including Sema3c an

92 pe of the semaphorin family, is an important axonal guidance molecule in vitro and in vivo.

93 hat in two rat models of liver fibrosis, the axonal guidance molecule neuropilin-1 (NRP-1) was upregu

94 e regulates local expression of netrin-1, an axonal guidance molecule that activates resolution, and

95 Semaphorin 3B (SEMA3B) is a secreted axonal guidance molecule that is expressed during develo

96 demonstrate that Semaphorin 4C (Sema4C), an axonal guidance molecule, plays a crucial role in B cell

97 We found that the axonal guidance molecules Sema3A and Sema3D were highly

98 The association of axonal guidance molecules with drug-induced reorganizati

99 pression of select members of this family of axonal guidance molecules, implicating Ephs, ephrins in

100 for a novel role for Netrins, best known as axonal guidance molecules, in modulating the morphogenet

101 Several of its members act as axonal guidance molecules.

102 ed PI3 kinase signaling and induced specific axonal guidance molecules.

103 nriched in genes involved in cell migration, axonal guidance, neurogenesis, and regulation of transcr

104 ase family that includes receptors signaling axonal guidance, neuronal bundling, and angiogenesis.

105 Eph family receptor tyrosine kinases signal axonal guidance, neuronal bundling, and angiogenesis; ye

106 ificant pathways involved neuronal function (axonal guidance, neuronal systems, and L1 cell adhesion

107 pocampal development exemplified by abnormal axonal guidance of dentate gyrus granule and mossy cells

108 adaptor protein that is known to function in axonal guidance paradigms in the fly including proper de

109 in inflammation, mitochondrial function and axonal guidance pathways, suggesting its regulation on m

110 partners, we have identified the Roundabout axonal guidance receptor Robo2 and its ligands Slit2 and

111 in mature neurons, but its potential role in axonal guidance remains elusive.

112 Eph and ephrins have been shown to regulate axonal guidance, segmentation, cell migration, and angio

113 altered transcripts are implicated in GR and axonal guidance signaling in dentate gyrus and dopamine

114 orin Signaling in Neurons," a member of the "Axonal Guidance Signaling System." At 1 week postinjecti

115 analysis also indicated an upregulation of "Axonal Guidance Signaling" pathway.

116 tory response and identified novel pathways, axonal guidance signaling, synaptic transmission, eIF2 a

117 involved in neuronal functions, for example, axonal guidance signaling.

118 system, regulates the response of neurons to axonal guidance signals.

119 to address specific questions extending from axonal guidance, synapse formation, or axonal transport

120 h dysregulation of brain mRNAs and miRNAs in axonal guidance, synaptic plasticity, mitochondria funct

121 eys and mammals suggest that the UNC5-Netrin axonal guidance system may play a role in limiting axona

122 implicates a function for DCC in additional axonal guidance systems not predicted from the knockout

123 lar matrix production, bone/joint formation, axonal guidance, vascular development, cell proliferatio

124 o understand mechanisms of OEC migration and axonal guidance, we injected lamina propria OECs 1 mm ro