ライフサイエンスコーパス: axonal sprouting

1 M may also be required for adult cholinergic axonal sprouting.

2 catecholamines) and initiating compensatory axonal sprouting.

3 p1 in GnRH neurons counteract Sema3A-induced axonal sprouting.

4 l protein that mediates myelin inhibition of axonal sprouting.

5 n the CNS may stabilize the node and prevent axonal sprouting.

6 ing GAP-43 or L1 showed minor enhancement of axonal sprouting.

7 ized aspiration lesions, which do not induce axonal sprouting.

8 t nonhuman primates retains the capacity for axonal sprouting.

9 onous neuronal activity after TCL as well as axonal sprouting.

10 he exception of NGF/Adts, failed to increase axonal sprouting.

11 during axonal regeneration, with overlap to axonal sprouting after stroke.

12 Semaphorin 3A (Sema3A), a known inhibitor of axonal sprouting, also alters vascular patterning.

13 to prevent neuronal degeneration, stimulate axonal sprouting and ameliorate behavioral deficits in v

14 ing both GAP-43 and L1 showed more extensive axonal sprouting and axonal growth into the proximal por

15 le (NCAM) expression in motor neurons during axonal sprouting and compensatory reinnervation was expl

16 ther actions, however, such as prevention of axonal sprouting and effects on G-protein-coupled recept

17 nction studies, we found that GDF10 produced axonal sprouting and enhanced functional recovery after

18 uromuscular junction denervation by inducing axonal sprouting and enhancing motor neuron viability.

19 ytoplasmic SRF (SRF-DeltaNLS-GFP) stimulated axonal sprouting and facial nerve regeneration in vivo.

20 ved signal mediated by prostacyclin triggers axonal sprouting and functional recovery in a mouse mode

21 Thus, GDF10 is a stroke-induced signal for axonal sprouting and functional recovery.

22 In contrast, moderate spontaneous axonal sprouting and induced-sprouting seen under differ

23 in periinfarct cortex and is an inhibitor of axonal sprouting and motor recovery in stroke.

24 act receptor expression may produce aberrant axonal sprouting and neuroaxonal dystrophy.

25 A mechanism based on axonal sprouting and occupancy of the vacant synaptic sp

26 expression of GAP43 (P < 0.01), a marker of axonal sprouting and plasticity, in the peri-infarct cor

27 Recovery from stroke is dependent on axonal sprouting and reconnection that occurs during a t

28 ry after stroke; knocking down GDF10 blocked axonal sprouting and reduced recovery.

29 ng nervous system development and facilitate axonal sprouting and regeneration after injury in the ad

30 LRP1 agonists significantly enhance sensory axonal sprouting and regeneration after spinal cord inju

31 CNS) have been implicated in the blocking of axonal sprouting and regeneration following injury.

32 ce that ciliary neurotrophic factor promotes axonal sprouting and regeneration in the periphery raise

33 e that the transplantation of BMSCs enhances axonal sprouting and rewiring into the denervated spinal

34 t 5 and 9 d postlesion, during the period of axonal sprouting and synaptogenesis, there was an increa

35 xperience led to topographically appropriate axonal sprouting and synaptogenesis.

36 et tissues stimulate sympathetic and sensory axonal sprouting and that an absence of p75NTR by sensor

37 ogo-NogoReceptor (NgR) pathway might enhance axonal sprouting and thereby recovery after focal brain

38 y of spared Nf1-/- DRG neurons for increased axonal sprouting, and by non-cell-autonomous contributio

39 ental switch in mTOR dependency for inducing axonal sprouting, and indicate that PTEN deletion in adu

40 B2 (CAErbB2) led to synaptic loss, exuberant axonal sprouting, and lethality at birth.

41 to limit neuroplasticity, activity-dependent axonal sprouting, and recovery in the adult.

42 nt of endogenous neurogenesis, angiogenesis, axonal sprouting, and synaptogenesis in the ischaemic br

43 rons, Schwann cell hyperplasia, and aberrant axonal sprouting around the medulla were observed in NGF

44 in the disease, associated with distal motor axonal sprouting as part of the reinnervation response t

45 ancement of the MDM2/p53-IGF1R axis enhances axonal sprouting as well as functional recovery after sp

46 hyperalgesia without denervation, and robust axonal sprouting at 5 months after surgery.

47 ratum (s.) oriens of the hippocampus exhibit axonal sprouting beyond their normal territory and inner

48 n on AD-related synaptotoxicity and aberrant axonal sprouting by ablating or overexpressing Fyn in hu

49 licated NGF in the regulation of cholinergic axonal sprouting by intact neurons projecting to the hip

50 se results confirm that post-lesion reactive axonal sprouting can be delayed in the central nervous s

51 he ability to respond to growth factors with axonal sprouting, cell hypertrophy, and activation of fu

52 combination leads to an additive increase in axonal sprouting compared with single treatments.

53 de; with the transcallosal and corticospinal axonal sprouting correlating with functional recovery.

54 s, fiber length as well as the morphology of axonal sprouting, deep within the tissue.

55 ntage of marked differences in the degree of axonal sprouting from contralateral homotypic cortex aft

56 es in the NL revealed that CH also prevented axonal sprouting from occurring.

57 s with reinnervation of denervated fibres by axonal sprouting from slow fibres.

58 Enhanced axonal sprouting from the ipsilesional pyramidal tract i

59 r these proteins in epigenetic regulation of axonal sprouting, growth factor-dependent survival of ne

60 The results showed that estrogen induces axonal sprouting in a brainstem-spinal pathway in the ad

61 Axonal sprouting in cortex adjacent to the infarct is pa

62 Recovery after stroke is associated with axonal sprouting in cortex adjacent to the infarct.

63 expression is increased in association with axonal sprouting in deafferented adult rat hippocampus.

64 ulated during the ovarian cycle and promotes axonal sprouting in hypothalamic neurons secreting gonad

65 ral stem cell development and is a marker of axonal sprouting in mid stages of embryonic development.

66 Stroke induces a unique microenvironment for axonal sprouting in periinfarct cortex, in which growth-

67 t contralateral cortical neurons may undergo axonal sprouting in the denervated striatum following a

68 In contrast, axonal sprouting in the hippocampus of hAPP mice was una

69 t that endogenous FGF-2 promotes cholinergic axonal sprouting in the injured adult brain.

70 is estrogen dependent, and estrogen induces axonal sprouting in the NRA-lumbosacral pathway.

71 The impairment of kindling-induced axonal sprouting in the null mutants could not be attrib

72 ospinal cell somata coincided with increased axonal sprouting in the spinal cord.

73 Thus, Nogo-A plays a role in restricting axonal sprouting in the young adult CNS after injury.

74 nic or viral blockade of NgR function allows axonal sprouting in vivo.

75 motor system drives significant spontaneous axonal sprouting instead of axon regeneration.

76 CISL induced vasopressinergic axonal sprouting into the external zone of the median em

77 ioral sparing is not clearly understood, but axonal sprouting is a likely candidate.

78 denervated neonatal muscles is deficient and axonal sprouting is absent.

79 Knowing the circuit-level determinants of axonal sprouting is important for repairing motor circui

80 emaining viable motor neurons; however, this axonal sprouting is insufficient to compensate for motor

81 due to dorsal column injuries is related to axonal sprouting is not known.

82 overy process, but the signal that initiates axonal sprouting is not known.

83 connections in areas denervated by a lesion (axonal sprouting) is more widespread than previously tho

84 critical for both proper axonal function and axonal sprouting, is inhibited by stroke and that this i

85 he results suggest that M1 injury results in axonal sprouting near the ischemic injury and the establ

86 The molecular systems that underlie axonal sprouting, neurogenesis, and gliogenesis after st

87 l period of neural development that includes axonal sprouting, neurogenesis, and surges of select neu

88 itic connectivity and contribute to aberrant axonal sprouting observed in AD patients.

89 exuberant neurite outgrowth and hippocampal axonal sprouting observed in knock-in mice expressing FA

90 ged in the denervated striatum suggests that axonal sprouting occurred in response to the lesion.

91 Local axonal sprouting occurs, producing an increase in unmyel

92 reviously demonstrated an unexpected, robust axonal sprouting of contralateral corticostriatal neuron

93 Axonal sprouting of corticospinal and raphespinal fibers

94 Axonal sprouting of excitatory neurons is frequently obs

95 tion (ECS) has been shown recently to induce axonal sprouting of granule cells in the rodent hippocam

96 We investigated whether central axonal sprouting of primary afferents spared by the rhiz

97 or all of the cortical hand map; 2) central axonal sprouting of spared primary afferents into the do

98 perilesional tissue, erythropoietin enhanced axonal sprouting of the contralesional, but not ipsilesi

99 ecovery, perilesional tissue remodelling and axonal sprouting of the corticorubral and corticobulbar

100 roke, bilateral innervation occurred through axonal sprouting of the uninjured CRT and CST.

101 001), axonal branching (P < 0.001), terminal axonal sprouting (P < 0.001)] were all present to an inc

102 s (TCL) of sensorimotor cortex, which induce axonal sprouting, produced two sequential patterns of lo

103 The regenerative and collateral axonal sprouting rates, blood vessel growth rate and Sch

104 As part of the disease process, an aberrant axonal sprouting response is known to occur near Abeta d

105 The axonal sprouting response is mediated by the trkA recept

106 d protein 43 (GAP-43), a molecular marker of axonal sprouting, showed a selective increase in GAP-43

107 n post-stroke angiogenesis, neurogenesis and axonal sprouting suggests a continuum of vascular and ne

108 Axonal sprouting that causes reorganization likely takes

109 ing spinal trauma, the limited physiological axonal sprouting that contributes to partial recovery of

110 ynaptic-cellular alterations (e.g., reactive axonal sprouting) that lead to dentate hyperexcitability

111 Axonal sprouting thus may provide a mechanism by which t

112 e added TrkB receptor ligands did not induce axonal sprouting to account for increased inhibitory syn

113 ted a trophic response to NGF in the form of axonal sprouting toward the NGF source.

114 ribution is explained by the wide pattern of axonal sprouting triggered by CAErbB2.

115 When axonal sprouting was implemented, the seizure threshold

116 perpetual axonal atrophy, degeneration, and axonal sprouting was observed over time, with increasing

117 rned neuronal activity and determine whether axonal sprouting was prevented.

118 s of lesions and in the blockade experiments axonal sprouting was strongly correlated with synchronou

119 n rat cerebellar slice cultures by promoting axonal sprouting with formation of vesicle-filled bouton

120 sters that appears to be caused by excessive axonal sprouting with the formation of new, smaller acet

121 Eight days after NGF/Adts injections, axonal sprouting within the dorsal horn was apparent, an