ライフサイエンスコーパス: axonemal dynein

1 mmaplysilla purea, which is known to inhibit axonemal dynein.

2 a specific centrin function associated with axonemal dynein.

3 identified as subunits of cytoplasmic and/or axonemal dyneins.

4 d to be light chains of both cytoplasmic and axonemal dyneins.

5 LCs) have been found in both cytoplasmic and axonemal dyneins.

6 e analogous to the B-link described for some axonemal dyneins.

7 do different things, as is the case for the axonemal dyneins.

8 play an essential role in the regulation of axonemal dynein activity and thus of ciliary and flagell

9 The addition of kinase inhibitor restored axonemal dynein activity concomitant with the dephosphor

10 In vitro axonemal dynein activity was reduced by the mia1-1 and m

11 amily proteins were originally identified in axonemal dyneins and subsequently found to function in m

12 fd3F regulates genes for Ch-specific axonemal dyneins and TRPV ion channels, which are requir

13 Axonemal dyneins are molecular motors that drive the bea

14 Axonemal dyneins are multisubunit enzymes that must be p

15 I1) and DNAI2, the first appreciated step in axonemal dynein arm assembly.

16 ilB homologs with presence of genes encoding axonemal dynein arm components.

17 mport into cilia and flagella, multi-subunit axonemal dynein arms are thought to be stabilized and pr

18 unchanged or become elevated, the density of axonemal dynein arms is reduced in reptin(hi2394) mutant

19 toplasmic assembly and/or trafficking of the axonemal dynein arms.

20 n and the other essential for assembling the axonemal dynein arms.

21 ized oda mutants, but only a partial loss of axonemal dyneins as shown by both electron microscopy an

22 nked form of PCD causing disruption of early axonemal dynein assembly.

23 provide direct evidence that mutations in an axonemal dynein can cause hydrocephalus.

24 These results show that axonemal dynein directly deciphers the tubulin code, whi

25 , and DIS3 as well as DNAH5, a member of the axonemal dynein family.

26 Dense populations of microtubules driven by axonemal dynein form large vortices, providing insights

27 ability of inner dynein arm I1 and wild-type axonemal dynein function.

28 arious cellular transport systems, including axonemal dyneins generating the force for ciliary and fl

29 Because axonemal dynein gliding assays are usually done using he

30 Gliding assays with axonemal dyneins have the unusual feature that the micro

31 allele of the testis-specifically expressed axonemal dynein heavy chain (axDHC) gene, Dnahc8, has be

32 acterized an insertional mutation in a mouse axonemal dynein heavy chain gene (Mdnah5) that reproduce

33 The axonemal dynein heavy chain gene Mdnah5 is specifically

34 culture demonstrated that the expression of axonemal dynein heavy chains correlated with the develop

35 fication and partial cloning of seven unique axonemal dynein heavy chains from rat tracheal epithelia

36 cells in culture regulated the expression of axonemal dynein heavy chains in a parallel fashion.

37 gulate the cell-specific expression of these axonemal dynein heavy chains will further our understand

38 level of conservation does not extend to the axonemal dynein heavy chains, suggesting functional diff

39 Here we report the positional cloning of an axonemal dynein heavy-chain gene, left/right-dynein (lrd

40 ity, can influence the activity of outer arm axonemal dynein in motility assays using purified protei

41 Pontin is essential for the stabilization of axonemal dynein intermediate chain 1 (DNAI1) and DNAI2,

42 Axonemal dynein is the molecular motor responsible for t

43 motile node cell monocilia and requires the axonemal dynein, left-right dynein (lrd).

44 An individual axonemal dynein molecule is capable of both unidirection

45 K40 acetylation increases and CTTs decrease axonemal dynein motility.

46 tory beating patterns, the activities of the axonemal dyneins must be coordinated both spatially and

47 Axonemal dyneins must be precisely regulated and coordin

48 Axonemal dyneins produce the motive force for ciliary an

49 To gain a further understanding of axonemal dynein regulation, mutant strains of Chlamydomo

50 melanogaster that codes for a sperm-specific axonemal dynein subunit.

51 sity directly influences the activity of the axonemal dyneins, the motors that drive the beating of t

52 to a higher rate of binding of Chlamydomonas axonemal dynein to Chlamydomonas microtubules than to po

53 ersity can directly regulate the activity of axonemal dyneins, we asked whether in vitro acetylation