ライフサイエンスコーパス: azoospermia

1 putative RNA-binding protein DAZ (Deleted in Azoospermia).

2 ociated with normospermia, oligospermia, and azoospermia.

3 and FSH values for identifying patients with azoospermia.

4 urvivors of childhood cancer are at risk for azoospermia.

5 ermatids leading to oligoteratozoospermia or azoospermia.

6 e and men at risk for temporary or permanent azoospermia.

7 f DNA repair defects in human nonobstructive azoospermia.

8 icular sperm retrieval in different types of azoospermia.

9 e more beneficial in cases of nonobstructive azoospermia.

10 CP3 is associated with human non-obstructive azoospermia.

11 small subgroup of males with nonobstructive azoospermia.

12 f1 exhibit male infertility characterized by azoospermia.

13 with the occurrence and development of human azoospermia.

14 who had documented low ejaculate volumes and azoospermia.

15 tations, which occurred in 7 of 289 men with azoospermia (2.4%), were absent in 384 controls with nor

16 After treatment, 34 (89%) patients had azoospermia, 4 (11%) had other dysspermia, and no patien

17 as 10 830 mg/m(2) (SD 7274) in patients with azoospermia, 8480 mg/m(2) (4264) in patients with oligos

18 e of the deletion males lack DAZ (Deleted in AZoospermia), a candidate gene for the azoospermia facto

19 homozygous male mutants are infertile due to azoospermia, a condition that was not appreciated in the

20 emen samples obtained from 289 patients with azoospermia and 384 controls.

21 serum testosterone levels, which resulted in azoospermia and infertility.

22 perm and boule mutant flies exhibit complete azoospermia and male sterility.

23 skeletal myopathy, hypocellular bone marrow, azoospermia and mitochondrial abnormalities in these mic

24 Disruption of spermatogenesis found in azoospermia and oligozoospermia is thought to be of prim

25 patients with varicoceles and nonobstructive azoospermia and to review predictors of successful outco

26 ility factors encoded by the DAZ (Deleted in Azoospermia) and DAZL (DAZ-like) genes.

27 The DAZ (Deleted in AZoospermia) and DAZLA (DAZ-like autosomal) genes may be

28 inding motif, Y chromosome), DAZ (deleted in azoospermia), and four recently isolated genes, have bee

29 fertility, atrophic testes with vacuolation, azoospermia, and spermatogenesis arrest.

30 The impact of this agent on spermatogenesis, azoospermia, and the developing fetus is discussed.

31 blood samples obtained from 15 patients with azoospermia, and we performed mutation screening by mean

32 About 13% of cases of non-obstructive azoospermia are caused by deletion of the azoospermia fa

33 Oligo- and azoospermia are severe forms of male infertility.

34 Oligozoospermia is far more common than azoospermia, but little is known about genetic causes.

35 epididymides and usually led to obstructive azoospermia by spermatoceles.

36 However, they were sterile, with azoospermia caused by a complete arrest of spermiogenesi

37 e other is BOULE, a member of the Deleted in Azoospermia (DAZ) gene family].

38 The Deleted in AZoospermia (DAZ) genes encode potential RNA-binding pro

39 Mutations in Deleted in Azoospermia (DAZ), a Y chromosome gene, are an important

40 ngation factor 1 alpha 1 (EF1A1), deleted in azoospermia (DAZ)-associated protein 2 (DAZAP2), ferriti

41 ZF) has been identified and named Deleted in Azoospermia (DAZ).

42 ain of Boule and a conserved DAZ (deleted in azoospermia) domain implicated in interactions with othe

43 ot considered possible just two decades ago, azoospermia due to testicular failure, including 47,XXY

44 A candidate gene for the Y-chromosome azoospermia factor (AZF) has been identified and named D

45 Deletion of the Azoospermia Factor (AZF) region of the human Y chromosom

46 ve azoospermia are caused by deletion of the azoospermia factor (AZF), a gene or gene complex normall

47 e is a candidate for the human Y-chromosomal Azoospermia Factor (AZF).

48 e previously sequenced one of these regions, azoospermia factor a (AZFa) and found that it spanned ap

49 Y, in both humans and mice and in humans the azoospermia factor AZF has been separated from HYA.

50 Deletions of the AZFc (azoospermia factor c) region of the Y chromosome are the

51 in male fertility and is a candidate for the azoospermia factor gene.

52 t maps to the same deletion interval as the 'azoospermia factor' (AZF).

53 Y chromosome is a strong candidate for the 'azoospermia factor' (AZF).

54 Deletions of the AZFa region (AZoospermia Factor-a) region of the human Y chromosome c

55 ed in AZoospermia), a candidate gene for the azoospermia factor.

56 he human Y chromosome-AZFa, AZFb, and AZFc ("azoospermia factors" a, b, and c)-are essential for norm

57 LE, the oldest member of the DAZ (Deleted in AZoospermia) family of genes, appears to have maintained

58 ng humans, suggests that the DAZ (Deleted in Azoospermia) gene and a closely related homolog, DAZL (D

59 The human DAZ (deleted in azoospermia) gene family on the Y chromosome and an auto

60 gene, a member of the human DAZ (deleted in azoospermia) gene family, within primates, within mammal

61 ologue of the human Y linked DAZ (deleted in azoospermia) gene from mouse.

62 for couples with reconstructible obstructive azoospermia have improved tremendously.

63 Regular menses in the patient and azoospermia in her husband delayed the diagnosis.

64 Targeted disruption of Dnmt3L caused azoospermia in homozygous males, and heterozygous progen

65 ns were a common cause of meiotic arrest and azoospermia in infertile men.

66 perm concentration, their ability to predict azoospermia in survivors of childhood cancer remains unc

67 The genetic basis of nonobstructive azoospermia is unknown in the majority of infertile men.

68 ith the Xenopus homolog of human Deleted for Azoospermia-like (DAZL) and the embryonic poly(A)-bindin

69 expression of the testis antigen deleted in azoospermia-like (DAZL) in CAFs.

70 cell-specific RNA-binding protein deleted in azoospermia-like (Dazl) is phosphorylated by MAPKAP kina

71 cellular mRNA-specific regulator, Deleted in Azoospermia-like (Dazl), also employs the PABP-eIF4G int

72 le splice isoforms 2 (Rbpms2) and Deleted in azoospermia-like (Dazl).

73 or the RNA-binding proteins DAZL (deleted in azoospermia-like) and CPEB (cytoplasmic polyadenylation

74 We observed that human DAZL (deleted in azoospermia-like) functions in primordial germ-cell form

75 Loss of boule function results in azoospermia; meiotic divisions are blocked, although lim

76 late in up to 56% of men with nonobstructive azoospermia (NOA) following varicocele repair.

77 Nonobstructive azoospermia (NOA) remains a challenging condition in rep

78 n the testes of patients with nonobstructive azoospermia (NOA) revealed enhanced expression of CYP19,

79 common loci contributing to non-obstructive azoospermia (NOA).

80 About 10% of males with idiopathic azoospermia or oligospermia have microdeletions in this

81 Azoospermia or oligozoospermia due to disruption of sper

82 Nine of the infertile men had azoospermia or severe oligospermia (sperm concentration,

83 Some infertile men with azoospermia or severe oligospermia have small deletions

84 deletion in a high percentage of males with azoospermia or severe oligospermia, and its homology wit

85 a significant proportion of men do not reach azoospermia or severe oligozoospermia, commensurate with

86 h an increased risk per 1000 mg/m(2) CED for azoospermia (OR 1.22, 95% CI 1.11-1.34), and for oligosp

87 ession of BRD7 was detected in the testes of azoospermia patients exhibiting spermatogenesis arrest t

88 loss, which was identical in 2 patients with azoospermia, predicts a deletion of 79 amino acids withi

89 There was no difference in azoospermia rate between patients treated with BEACOPP b

90 nited States reported a total of 14 cases of azoospermia secondary to inguinal vasal obstruction rela

91 of procedure should be based on the type of azoospermia, specific clinical circumstances, as well as

92 ve similar retrieval outcomes in obstructive azoospermia, testicular sperm extraction procedures appe

93 ations in human Piwi (Hiwi) in patients with azoospermia that prevent its ubiquitination and degradat

94 ion was present in a man with nonobstructive azoospermia (that is, no sperm was detected in semen), b

95 Of these men with azoospermia, the absence of sperm in semen, one in eight

96 protein homologous to human DAZ (Deleted in Azoospermia), vertebrate DAZL and Drosophila Boule prote

97 Azoospermia was noted in 53 (25%) of 214 participants, o

98 concentration >0 and <15 million per mL) and azoospermia were calculated with logistic regression mod

99 s will lead to a lack of mature sperm cells (azoospermia), which is a major cause of male infertility

100 ions were detected in 33 patients (15%) with azoospermia who received a diagnosis of azoospermia with

101 ed in an infertile male with oligospermia or azoospermia with low ejaculate volume, normal secondary

102 with azoospermia who received a diagnosis of azoospermia with meiotic arrest.

103 A null mutation of Sycp3 in mice causes azoospermia with meiotic arrest.

104 In contrast, testes of patients who had azoospermia with TEX11 mutations had meiotic arrest and

105 Azoospermia, with failure of the latter stages of sperma