ライフサイエンスコーパス: bHLH transcription factor

1 and ovary expressed basic helix-loop-helix (bHLH) transcription factor).

2 The C. elegans genome encodes a single Hand bHLH transcription factor.

3 ication is achieved through few well-defined bHLH transcription factors.

4 aling by Notch and Sox2 on the expression of bHLH transcription factors.

5 vation of NvHes genes, a conserved family of bHLH transcription factors.

6 heterodimerize with and negatively regulate bHLH transcription factors.

7 roviding new insight into gene regulation by bHLH transcription factors.

8 yase and pectinesterase, are targets of both bHLH transcription factors.

9 ic gene expression and activation by Myb and bHLH transcription factors.

10 partner for other developmentally regulated bHLH transcription factors.

11 repression domain in the E protein family of bHLH transcription factors.

12 epends on Olig2, one of the five Olig family bHLH transcription factors.

13 forms homodimers and heterodimers with other bHLH transcription factors.

14 in its capacity as a basic helix-loop-helix (bHLH) transcription factor.

15 hogenesis is HFR1, a basic helix-loop-helix (bHLH) transcription factor.

16 hocytes, encodes a basic helix--loop--helix (bHLH) transcription factor.

17 tivity of neurogenic basic helix-loop-helix (bHLH) transcription factors.

18 ly activate myogenic basic helix-loop-helix (bHLH) transcription factors.

19 ting the function of basic-helix-loop-helix (bHLH) transcription factors.

20 ich are targets of basic helix--loop--helix (bHLH) transcription factors.

21 odes the E47 and E12 basic helix-loop-helix (bHLH) transcription factors.

22 Although Achaete-scute family bHLH transcription factor 1 (Ascl1) plays important role

23 n of sT and the cell fate-determinant atonal bHLH transcription factor 1 (ATOH1) leads to development

24 a complex with the Notch effector hes family bHLH transcription factor 1 (HES1) and the protein deace

25 nding factor 1 (LEF1) and mesoderm posterior BHLH transcription factor 1 (MESP1; from mesoderm to car

26 tivation protein Ascl1 (achaete-scute family bHLH transcription factor 1) in proliferating hippocampa

27 sion of either Twist1 (encoding twist family bHLH transcription factor 1, known as Twist) or Snai1 (e

28 iscovered that the gene single minded family bHLH transcription factor 1a (sim1a) is dynamically expr

29 which encodes a photomorphogenesis-promoting bHLH transcription factor, acts downstream of SPA1 and i

30 maize R gene has been used to suggest that a bHLH transcription factor also participates in this proc

31 DYT1 encodes a putative bHLH transcription factor and is strongly expressed in t

32 s deduced where targets, such as AP2/ERF and bHLH transcription factors and chromatin remodelers form

33 lators of neurogenesis, including neurogenic bHLH transcription factors and dorsal interneuron progen

34 Designer TALEs (dTALEs) for the bHLH transcription factors and the pectate lyase, but no

35 ed genes that could be direct targets of the bHLH transcription factors and therefore indirect target

36 rabidopsis, a ternary complex formed by MYB, bHLH transcription factors and TTG1 modulates unicellula

37 development through basic-helix-loop-helix (bHLH) transcription factors and promotes astrocytosis.

38 ered that it encodes a PAS-domain-containing bHLH transcription factor, and that it is expressed in a

39 h encodes a class II basic helix-loop-helix (bHLH) transcription factor, and causes Saethre-Chotzen s

40 cell cycle proteins, basic helix-loop-helix (bHLH) transcription factors, and other retinal cell mark

41 Instead, our results suggest that bHLH transcription factors are regulated by a previously

42 ut the Hey family of basic helix-loop-helix (bHLH) transcription factors are candidates for mediating

43 Proneural basic helix-loop-helix (bHLH) transcription factors are critical positive regula

44 Neural basic helix-loop-helix (bHLH) transcription factors are crucial in regulating th

45 E protein family of basic helix-loop-helix (bHLH) transcription factors are important for tissue-spe

46 Basic helix-loop-helix (bHLH) transcription factors are key regulators of neurog

47 Basic helix-loop-helix (bHLH) transcription factors are required for the develop

48 lacodes in the zebrafish, Danio rerio, using bHLH transcription factors as molecular markers.

49 rl), a Hairy-related basic helix-loop-helix (bHLH) transcription factor, as a negative regulator of c

50 ediated overexpression of a single gene, the bHLH transcription factor Ascl1, redirected the fate of

51 tube depends on the basic helix-loop-helix (bHLH) transcription factors Ascl1 (Mash1) and Neurog2 (N

52 We identified a basic helix-loop-helix (bHLH) transcription factor at chickpea's B locus that co

53 In a wide range of vertebrate species, the bHLH transcription factor Ath5 is tightly associated wit

54 retinoblasts, and functions upstream of the bHLH transcription factors ath5/atoh7 and neurod, and th

55 on resulted from an increase in the level of bHLH transcription factor Atoh1 in response to inhibitio

56 ns share a developmental requirement for the bHLH transcription factor Atoh1.

57 n the temporal and spatial regulation of the bHLH transcription factor Atoh1.

58 n depends on the regulated expression of the bHLH transcription factor Atoh1.

59 he expression of the basic helix-loop-helix (bHLH) transcription factor Atoh1.

60 The vertebrate basic helix-loop-helix (bHLH) transcription factor ATOH7 (Math5) is specifically

61 itors expressing the basic helix-loop-helix (bHLH) transcription factor, Atoh7, which is necessary fo

62 a mouse homolog of the Drosophila proneural bHLH transcription factor Atonal, is essential in the de

63 The basic helix-loop-helix (bHLH) transcription factor Atonal (Ato) plays an essenti

64 hree closely related basic helix-loop-helix (bHLH) transcription factors, BEE1, BEE2, and BEE3, as pr

65 insect and RNAi to determine functions of 19 bHLH transcription factors belonging to PAS and HES fami

66 The basic helix-loop-helix (bHLH) transcription factor Bhlhb4 was found to be expres

67 ce deficient for the basic helix-loop-helix (bHLH) transcription factor Bhlhe40 (Bhlhe40(-/-)) are re

68 Zfp148, and Plzf, overexpress a novel Tohlh2 bHLH transcription factor, but lack LIM homeobox gene Lh

69 mentation assays, we documented that the two bHLH transcription factors can dimerize in planta.

70 first neural target of Ptf1a and revealing a bHLH transcription factor cascade functioning in the spe

71 Our results reveal that a bHLH transcription factor cascade is involved in regulat

72 ng the hairy-related basic helix-loop-helix (bHLH) transcription factor CHF1/Hey2 develop a thin-wall

73 Basic helix-loop-helix (bHLH) transcription factors control developmental decisi

74 How basic helix-loop-helix (bHLH) transcription factors control neurogenesis and neu

75 f the MyoD family of basic helix-loop-helix (bHLH) transcription factors control the formation of all

76 of master regulatory basic-helix-loop-helix (bHLH) transcription factors controls the initiation, pro

77 with NE features by modulating the action of bHLH transcription factors critical for neuronal differe

78 NeuroD is a basic helix-loop-helix (bHLH) transcription factor critical for determining neur

79 pression of specific basic-helix-loop-helix (bHLH) transcription factors defines many types of cellul

80 We identified a basic helix-loop-helix (bHLH) transcription factor, designated PHYTOCHROME-INTER

81 have identified two basic helix-loop-helix (bHLH) transcription factors, designated PHYTOCHROME-INTE

82 e, both display significant overlap with the bHLH transcription factor DIMM, a known neuroendocrine (

83 ate the expression and function of proneural bHLH transcription factors during the onset of mouse ret

84 as EMT inducers, among them, Snail1 and the bHLH transcription factor E47.

85 bers of the group XI basic helix-loop-helix (bHLH) transcription factors encoded by LOTUS JAPONICUS R

86 es expression of two basic helix loop helix (bHLH) transcription factor encoding genes, ash1a (achaet

87 enes in opr3 encode lipoxygenase, a putative bHLH transcription factor, epithiospecifier protein and

88 ECs express mAsh1, a basic helix-loop-helix (bHLH) transcription factor essential for NE cell differe

89 3, neurogenin1) is a basic helix-loop-helix (bHLH) transcription factor essential for neuronal differ

90 Here, we characterize Sage, a bHLH transcription factor expressed exclusively in the D

91 MyoR and capsulin are related bHLH transcription factors expressed in specific facial

92 HAND2 (dHAND) is a basic helix-loop-helix (bHLH) transcription factor expressed in numerous tissues

93 Ngn1 is a basic helix-loop-helix (bHLH) transcription factor expressed in specific regions

94 OLIG1 and OLIG2 are basic-helix-loop-helix (bHLH) transcription factors expressed in the pMN domain

95 g, which has previously been shown to induce bHLH transcription factor expression, increased beta-cat

96 cies, Arabidopsis, in which three paralogous bHLH transcription factors, FAMA, MUTE and SPCH, control

97 gested that the large-scale expansion of the bHLH transcription factor family occurred before the div

98 g the composition and diversity of the apple bHLH transcription factor family that will provide a pla

99 Members of the basic helix-loop-helix (bHLH) transcription factor family play an essential role

100 The basic helix-loop-helix (bHLH) transcription factor family regulates numerous dev

101 Class I Basic Helix-Loop-Helix (bHLH) transcription factors form homodimers or heterodim

102 e identification and characterization of 175 bHLH transcription factors from apple (Malus x domestica

103 nteracting Factors (PIFs) by releasing these bHLH transcription factors from phytochrome B-mediated i

104 jasmonate-regulated basic helix-loop-helix (bHLH) transcription factor from clade IVa inducing the m

105 iation and provide further evidence that non-bHLH transcription factors function in the neuronal diff

106 eurogenin3 (ngn3), a basic helix-loop-helix (bHLH) transcription factor, functions as a pro-endocrine

107 ults suggest that variation in the timing of bHLH transcription factor gene expression can explain th

108 ch signaling revealed a cascade of proneural bHLH transcription factor gene expression that correlate

109 e control of the regulatory sequences of the bHLH transcription factor gene hand2.

110 Phylogenetic analysis indicates that these bHLH transcription factor genes are orthologous to Arabi

111 We show that basic helix-loop-helix (bHLH) transcription factor genes represented by Glyma04g

112 utative (a PIL5, a hypothetic protein, and a bHLH transcription factor) genes based on the annotated

113 s the Notch effector basic helix-loop-helix (bHLH) transcription factor hairy and enhancer of split 1

114 the highly conserved basic helix-loop-helix (bHLH) transcription factor Hand is expressed in cardiobl

115 The bHLH transcription factor Hand1 (Heart and neural crest-

116 The basic helix-loop-helix (bHLH) transcription factor HAND1 (also called eHAND) is

117 upregulation of the basic helix-loop-helix (bHLH) transcription factor Hand1, restricted exclusively

118 ebrafish of two edn1 downstream targets, the bHLH transcription factor Hand2 and the homeobox transcr

119 The bHLH transcription factor Hand2 is essential for cardiac

120 Here, we show that the bHLH transcription factor Hand2 limits the size of the e

121 The basic helix-loop-helix (bHLH) transcription factor Hand2 has been implicated in

122 The basic helix-loop-helix (bHLH) transcription factor Hand2 has been implicated in

123 The basic helix-loop-helix (bHLH) transcription factor Hand2 has been shown to play

124 The basic helix-loop-helix (bHLH) transcription factor Hand2 is required for growth

125 The MyoD family of basic helix-loop-helix (bHLH) transcription factors has the remarkable ability t

126 1, a phy-interacting basic helix-loop-helix (bHLH) transcription factor, has been shown to negatively

127 olecular level that neuronal differentiation bHLH transcription factors have distinct lineage-specifi

128 The genes encoding basic helix-loop-helix (bHLH) transcription factors have been implicated in many

129 (2014) describe the signals regulated by the bHLH transcription factor HEC1 during Arabidopsis stem c

130 Here, we show that the bHLH transcription factors HECATE 1 (HEC1), HEC2 and HEC

131 s for expression of Notch and the hes family bHLH transcription factor (HES1) in colon tissues from m

132 by interfering with the assembly of myogenic bHLH transcription factor heterodimers on E-box sequence

133 Here, we report that the Beta3/Olig-type bHLH transcription factor hlh-16 is L/R asymmetrically e

134 h sexes requires the basic-helix-loop-helix (bHLH) transcription factor HLH-2, the sole ortholog of t

135 ere, we identify the basic helix-loop-helix (bHLH) transcription factor homolog of brassinosteroid en

136 d degradation of the basic helix-loop-helix (bHLH) transcription factor human achaete-scute homolog 1

137 lutionally conserved basic helix-loop-helix (bHLH) transcription factors implicated in development of

138 ) demonstrate unsuspected cross-talk between bHLH transcription factors, important regulators of orga

139 olated a dominant mutation in an R/B-related bHLH transcription factor in the course of studying Arab

140 l cues in the CNS and to examine the role of bHLH transcription factors in adult tissue regeneration.

141 y PHYTOCHROME-INTERACTING FACTOR (PIF)-class bHLH transcription factors in darkness, but light-activa

142 Two bHLH transcription factors in this network, Olig1 and Ol

143 lle kinase and Twist basic helix-loop-helix (bHLH) transcription factor in transducing Toll signaling

144 l1), which encodes a basic helix-loop-helix (bHLH) transcription factor, in the regulation of both as

145 ibit the function of basic helix-loop-helix (bHLH) transcription factors including those that regulat

146 oteins are known to negatively regulate many bHLH transcription factors, including Math1, in a number

147 in-22, a Hes-related basic helix-loop-helix (bHLH) transcription factor, increase seam cell number va

148 inhibit the atypical basic helix-loop-helix (bHLH) transcription factor INCREASED LEAF INCLINATION1 B

149 e show that myogenic basic helix-loop-helix (bHLH) transcription factors induce myomaker expression i

150 Conversely, activation of bHLH transcription factors induces a cluster of genes wi

151 irect target of EZH2, and repression of this bHLH transcription factor is critical for neuronal diffe

152 We show that the REF-1 family of bHLH transcription factors is a major target of Notch si

153 We have found that Scleraxis, a bHLH transcription factor, is a highly specific marker f

154 The scleraxis (Scx) gene, encoding a bHLH transcription factor, is expressed in the progenito

155 Twist1, a class II basic-helix-loop-helix (bHLH) transcription factor, is expressed during early EC

156 showed that Math1, a basic helix-loop-helix (bHLH) transcription factor, is expressed in the gut.

157 report that Ptf1a, a basic-helix-loop-helix (bHLH) transcription factor, is transiently expressed by

158 mologue 2 (Ascl2)--a basic helix-loop-helix (bHLH) transcription factor--is selectively upregulated i

159 The basic helix-loop-helix (bHLH) transcription factors known as E proteins and thei

160 The Mnt gene encodes a Mad-family bHLH transcription factor located on human 17p13.3.

161 ow that expression of olig2, which encodes a bHLH transcription factor, marks a distinct subset of ne

162 Scleraxis (Scx), a bHLH transcription factor, marks this somitic tendon pro

163 The bHLH transcription factors Mash1 and Ngn2 have distinct

164 The basic helix-loop-helix (bHLH) transcription factor Math1 (also called Atoh1) is

165 mechanism that involved the upregulation of bHLH transcription factor, Math1 (mouse Atoh1), differen

166 The basic helix-loop-helix (bHLH) transcription factor Math5 (Atoh7) is transiently

167 The Wnt-regulated basic helix-loop-helix (bHLH) transcription factor mesogenin 1 (Msgn1) has been

168 al profiling of Wnt3a (-/-) embryos that the bHLH transcription factor, Mesogenin1 (Msgn1), is a dire

169 The bHLH transcription factor Mesp has an essential but ambi

170 gastric cell populations that identified the bHLH transcription factor Mist1 as a potential ZC regula

171 In mice, expression of the bHLH transcription factor MIST1, normally restricted to

172 JAZ13 interacts with the bHLH transcription factor MYC2 and the co-repressor TOPL

173 conserved E-box is a target for the myogenic bHLH transcription factors MYF5 and MYOD.

174 The basic helix-loop-helix (bHLH) transcription factor Myod directly regulates gene

175 BMP4 stimulation promotes Id2 binding to the bHLH transcription factor NeuroD, which is required for

176 ar expression of the basic helix-loop-helix (bHLH) transcription factor neuroD in the persistently ne

177 sient and prefigures expression of a related bHLH transcription factor, neuroD.

178 , we have identified basic helix-loop-helix (bHLH) transcription factors Neurod2 and Neurod6 as key r

179 The basic helix-loop-helix (bHLH) transcription factor, neuroD2, induces neuronal di

180 The bHLH transcription factor Neurog1 (Ngn1, Neurod3, neurog

181 ion of the proneural basic helix-loop-helix (bHLH) transcription factors NEUROG1 and NEUROD1.

182 ly by regulating two basic helix-loop-helix (bHLH) transcription factors, Neurog1 and Neurog2.

183 ion of the proneural basic helix-loop-helix (bHLH) transcription factors Neurog2 or Ascl1 downregulat

184 We identified the basic helix-loop-helix (bHLH) transcription factor Neurogenic Differentiation 2

185 at in addition to inducing neurogenesis, the bHLH transcription factor neurogenin (Ngn1) inhibits the

186 up-regulates transcription of the proneural bHLH transcription factor neurogenin 1 (ngn1).

187 enhancers, including basic helix-loop-helix (bHLH) transcription factor Neurogenin/Math/atonal and Ma

188 to derive an EGFP-marked null allele of the bHLH transcription factor, neurogenin 3 (ngn3).

189 Expression of the basic helix-loop-helix (bHLH) transcription factor Neurogenin1 (Neurog1) coincid

190 Here we demonstrate that the bHLH transcription factor Neurogenin2 (Ngn2) is both nec

191 is is positively regulated by the pro-neural bHLH transcription factors Ngn1 and NeuroD, but the fact

192 ells proliferate and transiently express the bHLH transcription factor Ngn3.

193 The ability of the bHLH transcription factors Ngnr1 and NeuroD to drive neu

194 eport that proneural basic helix-loop-helix (bHLH) transcription factors not only initiate neuronal d

195 enesis and depends upon the function of both bHLH transcription factors, notably Hand2, and homeodoma

196 demonstrate that the expression of Bhlhb5, a bHLH transcription factor of the Olig family, is tightly

197 Skeletal myogenesis is controlled by bHLH transcription factors of the MyoD family that, alon

198 he activity of three basic-helix-loop-helix (bHLH) transcription factors of the PHYTOCHROME INTERACTI

199 Against this backdrop, the bHLH transcription factor Olig2 in the oligodendrocyte l

200 The bHLH transcription factor Olig2 is essential for motoneu

201 The bHLH transcription factor Olig2 is expressed in cycling

202 , Zfp488 can interact and cooperate with the bHLH transcription factor Olig2 to promote precocious an

203 oma and with more recent observations on the bHLH transcription factor Olig2.

204 ing neural tube, the basic helix-loop-helix (bHLH) transcription factor Olig2 interacts with the home

205 N) domain of the developing spinal cord, the bHLH transcription factor, Olig2, plays critical roles i

206 We show that the basic helix-loop-helix (bHLH) transcription factor Olig3 is expressed in the ent

207 TAL1/SCL is a basic helix-loop-helix (bHLH) transcription factor oncogene aberrantly expressed

208 Finally, we demonstrate that the bHLH transcription factor paraxis, which was previously

209 m by which increasing temperature causes the bHLH transcription factor PHYTOCHROME INTERACTING FACTOR

210 ncreased auxin biosynthesis, mediated by the bHLH transcription factor PHYTOCHROME-INTERACTING FACTOR

211 CCA1 regulates growth via the bHLH transcription factors PHYTOCHROME INTERACTING FACTO

212 We conclude that bHLH transcription factors PIF1, PIF3, PIF4, and PIF5 ac

213 (pifq) lacking four phytochrome-interacting bHLH transcription factors (PIF1, 3, 4, and 5) is consti

214 (phy)-interacting factor (PIF) subfamily of bHLH transcription factors (PIF1, PIF3, PIF4, and PIF5).

215 hange and respond by directly contacting two bHLH transcription factors, PIF4 and PIF5.

216 We show that the basic helix-loop-helix (bHLH) transcription factor PIF7 (phytochrome-interacting

217 as SPA1/COP1 E3 ubiquitin ligase complex and bHLH transcription factors PIFs, would partially explain

218 family of four Phytochrome (phy)-Interacting bHLH transcription Factors (PIFs) collectively promote s

219 n of phy-interacting basic Helix Loop Helix (bHLH) transcription factors (PIFs), such as PIF3, thereb

220 Proneural basic helix-loop-helix (bHLH) transcription factors play a central role in regul

221 Basic helix-loop-helix (bHLH) transcription factors play a pivotal role in the r

222 Long Hypocotyl in Far-Red Light 1 (HFR1), a bHLH transcription factor, plays a critical role in prom

223 DYSFUNCTIONAL TAPETUM 1 (DYT1), a putative bHLH transcription factor, plays a critical role in regu

224 Twist, a basic helix-loop-helix (bHLH) transcription factor, plays an important role in m

225 ycle-specific iron deficiency response and a bHLH transcription factor, POPEYE (PYE), that may play a

226 Here we show that Arabidopsis lacking two bHLH transcription factors produces pollen without sperm

227 The basic helix-loop-helix (bHLH) transcription factor PTF1a is critical to the deve

228 The basic helix-loop-helix (bHLH) transcription factor Ptf1a is essential for the ge

229 We demonstrated that the bHLH transcription factor R1 and hexokinase HEX9 might a

230 Basic helix-loop-helix (bHLH) transcription factors recognize the canonical E-bo

231 Neural basic helix-loop-helix (bHLH) transcription factors regulate neurogenesis in ver

232 Core basic helix-loop-helix (bHLH) transcription factors regulating stomatal developm

233 the SPATULA (SPT) gene, which also encodes a bHLH transcription factor required for development of th

234 subpopulation of NCCs that expresses Ngn2, a bHLH transcription factor required for sensory neurogene

235 Mesp encodes a bHLH transcription factor required for specification of

236 lfactory-1, OLF1), a basic helix-loop-helix (bHLH) transcription factor required for B-lineage commit

237 gene that encodes a basic helix-loop-helix (bHLH) transcription factor required for proper distal ti

238 r-specific predicted basic helix-loop-helix (bHLH) transcription factor required for tapetal differen

239 oneural genes encode basic-helix-loop-helix (bHLH) transcription factors required for neural precurso

240 al sensor of mitochondrial function, and the bHLH transcription factors Rtg1p and Rtg3p.

241 The bHLH transcription factor SCL plays a central role in th

242 In summary, we conclude that the bHLH transcription factors SHARP1 and SHARP2 are involve

243 The bHLH transcription factors SHARP1 and SHARP2 are partial

244 the function of the basic helix-loop-helix (bHLH) transcription factor SPEECHLESS (SPCH).

245 This includes the basic helix-loop-helix (bHLH) transcription factors SPEECHLESS (SPCH), MUTE, FAM

246 ila retina, stochastic expression of the PAS-bHLH transcription factor Spineless (Ss) controls photor

247 ophila eye, stochastic expression of the PAS-bHLH transcription factor Spineless (Ss) determines a ra

248 A complex of R2R3-MYB and bHLH transcription factors, stabilized by WD40 repeat pr

249 Among the bHLH transcription factors studied, the steroid receptor

250 receptor family (phyA to phyE) interact with bHLH transcription factors, such as PIF3, and induce cha

251 Prior work has implicated the bHLH transcription factor Tal1 in endocardial tube forma

252 Here, we describe the role of a bHLH transcription factor, Tcf21 (epicardin/Pod1/capsuli

253 interaction of Pfr with a small subfamily of bHLH transcription factors, termed Phy-Interacting Facto

254 Two classes of JA-responsive bHLH transcription factor (TF), CrMYC2 and BIS1/BIS2, ar

255 Atoh1, a basic helix-loop-helix (bHLH) transcription factor (TF), is essential for the di

256 ing nuclear localization and activity of the bHLH transcription factor Tfe3.

257 YC2a, b, c) encoding basic helix-loop-helix (bHLH) transcription factors (TFs) whose expression is ra

258 f two genes encoding basic-helix-loop-helix (bHLH) transcription factors (TFs), NtMYC2a and NtMYC2b f

259 Sohlh1 represents the first testis-specific bHLH transcription factor that is essential for spermato

260 Neurogenin 3 is a bHLH transcription factor that is expressed in the devel

261 including IAA-Leu Resistant3 (ILR3), another bHLH transcription factor that is involved in metal ion

262 endent, per ARNT-sim (PAS) domain containing bHLH transcription factor that mediates adaptive respons

263 TWIST is a bHLH transcription factor that promotes epithelial-mesen

264 Twist1 is a bHLH transcription factor that regulates cell proliferat

265 his question, we focused on Atoh1 (Math1), a bHLH transcription factor that specifies distinct neuron

266 ith inhibition of the Notch effector Hey1, a bHLH transcription factor that we here characterize as a

267 , BEE1 and BEE3 genes encode closely related bHLH transcription factors that act redundantly to speci

268 MYC2, MYC3 and MYC4 are JAZ-interacting bHLH transcription factors that play a major role in con

269 The bHLH transcription factors that regulate early developme

270 nctions of Myf5 and MyoD, two highly related bHLH transcription factors that regulate skeletal muscle

271 is a multifunctional basic helix-loop-helix (bHLH) transcription factor that has been shown to be a p

272 molog 1 (Atoh1) is a basic helix-loop-helix (bHLH) transcription factor that is essential for the gen

273 Mist1 is a basic helix-loop-helix (bHLH) transcription factor that is important to the prop

274 S (SPCH), encoding a basic helix-loop-helix (bHLH) transcription factor that is necessary and suffici

275 PTF1a is an unusual basic helix-loop-helix (bHLH) transcription factor that is required for the deve

276 are closely related basic helix-loop-helix (bHLH) transcription factors that are expressed in myelin

277 s (PIFs) are nuclear basic helix-loop-helix (bHLH) transcription factors that negatively regulate pho

278 des highly conserved basic helix-loop-helix (bHLH) transcription factors that play crucial roles in c

279 n TWIST2 and TWIST1 encode highly homologous bHLH transcription factors, the finding that TWIST2 rece

280 hese results uncover a novel mechanism for a bHLH transcription factor to recognize a unique spatial

281 a functionally relevant target recruited by bHLH transcription factors to induce cell cycle arrest i

282 he ability of neural basic helix-loop-helix (bHLH) transcription factors to activate transcriptional

283 D family of myogenic basic helix-loop-helix (bHLH) transcription factors to control the expression of

284 h the MyoD family of basic helix-loop-helix (bHLH) transcription factors to drive skeletal muscle dev

285 ing (IDs) antagonize basic-helix-loop-helix (bHLH) transcription factors to inhibit differentiation a

286 ermal subdivision requires regulation of the bHLH transcription factor Twist.

287 f the 29 candidate genes in this region, the bHLH transcription factor, TWIST2, was initially sequenc

288 STRA13 is a pVHL-dependent bHLH transcription factor up-regulated on the mRNA level

289 a nonsynonymous SNP mutation on exon 5 of a bHLH transcription factor was found to elevate the propo

290 vonol-4-reductase (DFR) in leaves, whereas a bHLH transcription factor was highly correlated with fla

291 To determine whether this bHLH transcription factor was necessary for normal brain

292 d by specific markers, and the expression of bHLH transcription factors was assessed.

293 Basic helix-loop-helix (bHLH) transcription factors were reduced, while secondar

294 y32 (ms32) encodes a basic helix-loop-helix (bHLH) transcription factor, which functions as an import

295 The stem cell leukemia (SCL) gene encodes a bHLH transcription factor with a pivotal role in hematop

296 The stem cell leukemia (SCL) gene encodes a bHLH transcription factor with a pivotal role in hemopoi

297 (SCL) gene encodes a basic helix-loop-helix (bHLH) transcription factor with an essential role in spe

298 enes encode putative basic helix-loop-helix (bHLH) transcription factors with overlapping functionali

299 up-regulation of two basic helix-loop-helix (bHLH) transcription factors with predicted effector bind

300 We have identified a novel bHLH transcription factor, ZHOUPI (ZOU), which mediates