ライフサイエンスコーパス: bZIP protein

1 rn is similar to that of Tef, an Hlf-related bZIP protein.

2 through RsmA, a recently discovered YAP-like bZIP protein.

3 ta mRNA to the K8alpha mRNA that encodes a K-bZIP protein.

4 inhibit major-groove DNA binding by the GCN4 bZip protein.

5 n of proteasomal-mediated degradation of the bZIP protein.

6 n between basic DNA binding regions of three bZIP proteins.

7 at all with c-myc, max or unrelated bHLH or bZIP proteins.

8 bine to determine DNA-binding specificity of bZIP proteins.

9 e of electrostatic effects in DNA bending by bZIP proteins.

10 charges distal to the basic region in bound bZIP proteins.

11 ore the mechanism by which pX interacts with bZIP proteins.

12 ctions can play a key role in DNA bending by bZIP proteins.

13 nal regulatory properties of HLF and related bZIP proteins.

14 tely different consensus not shared by other bZIP proteins.

15 modimerize and do not form dimers with other bZip proteins.

16 oove in the presence of major-groove binding bZip proteins.

17 via a physical interaction with ABI5-related bZIP proteins.

18 eq's potential to dimerize with a variety of bZIP proteins.

19 decreases the kinetic specificity of certain bZIP proteins.

20 core recognition element bound by canonical bZIP proteins.

21 e by Maf differ from those made by canonical bZIP proteins.

22 EB) is a member of the CREB/ATF subfamily of bZIP proteins.

23 omotes dimerization of CREB as well as other bZIP proteins.

24 zed by EmBP-1, a wheat basic/leucine zipper (bZIP) protein.

25 interact with specific basic-leucine zipper (bZIP) proteins.

26 the biology of basic region-leucine zipper (bZIP) proteins.

27 The elongated HYPOCOTYL5 (HY5) bZIP protein, an integrator of multiple signaling pathwa

28 e show that COP1 negatively regulates HY5, a bZIP protein and a positive regulator of photomorphogeni

29 he PAR (proline- and acid-rich) subfamily of bZIP proteins and has DNA-binding specificity like that

30 documented specific interactions among these bZIP proteins and the kinases that could activate them a

31 rd elucidating the in vivo function of plant bZIP proteins and their related G-box cis elements, we h

32 nds DNA through a basic region like those of bZIP proteins and through a flexible amino-terminal arm

33 emerges from their interactions with related bZIP proteins and with structurally unrelated transcript

34 been shown to encode a basic-leucine zipper (bZIP) protein and to function in narrowing the region fr

35 o the family of basic region/leucine zipper (bZIP) proteins and interacts with the cAMP responsive el

36 te binding with basic-region leucine zipper (bZIP) proteins and other transcription factors.

37 mplexes between basic region leucine zipper (bZIP) proteins and target DNA, the relationship between

38 structural reorganizations induced in DNA by bZIP proteins, and lead to a revision of the relationshi

39 Two genes encoding bZIP proteins are expressed in flowers of Antirrhinum ma

40 ugh the basic regions in naturally occurring bZip proteins are located N-terminal to the leucine zipp

41 The basic leucine zipper (bZIP) proteins are one of the largest and most conserved

42 Basic region leucine zipper (bZIP) proteins are transcription factors that interact s

43 We used a natural bZIP protein as our host-guest system that remains dimer

44 , including the basic region-leucine zipper (bZIP) protein ATF-2-c-jun, are well-characterized compon

45 e excretory duct cell) together with another bZip protein, ATF-2.

46 Here it is shown that bZIP proteins bend DNA via a mechanism involving direct

47 tion function and to define the nature of K8 bZip protein binding to the origin, we constructed conse

48 -mRNAs and reduced expression of ORF50 and K-bZIP proteins but had no effect on latency-associated nu

49 oter that is recognized by a large number of bZIP proteins, but with much greater stability.

50 ilar to those found in basic leucine zipper (bZIP) proteins, but lacks any apparent leucine zipper.

51 We show that the bZIP protein C/EBP beta isoform LIP is required for nucl

52 Nrl was more effective than the related bZIP proteins, c-Fos and c-Jun, in stimulating rhodopsin

53 native names, (b) dimer formation with other bZip proteins, (c) transcriptional activity, and (d) pot

54 ically with the basic-domain/leucine-zipper (bZip) protein, cAMP response element binding protein (CR

55 The ability of Tax to enhance DNA binding of bZip proteins can be explained in part by Tax dimerizati

56 nd perhaps the specificity of DNA binding by bZIP proteins can be modulated by incorporating a stably

57 , and illustrate several mechanisms by which bZIP proteins can regulate multiple, seemingly disparate

58 ng can partly bypass the requirement for the bZip protein CEBP-1, a downstream factor of the DLK-1 ki

59 ontributes to the species differences is the bZip protein CES-2.

60 Caenorhabditis elegans basic leucine zipper (bZip) protein CES-2 regulates the transcription of diffe

61 we cloned the human homologue of TEF/VBP, a bZIP protein closely related to HLF.

62 tivating transcription factor-1 subfamily of bZip proteins, constitute the contact surface for Tax.

63 bZip proteins contain a bipartite DNA-binding motif cons

64 Basic-region leucine zipper (bZip) proteins contain a bipartite DNA-binding motif con

65 fusion and the basic leucine zipper domain (bZip) protein CREB (cAMP response element-binding protei

66 ave identified a novel basic leucine zipper (bZIP) protein, designated ATF-7, that physically interac

67 We have investigated how plant bZIP proteins determine their DNA binding specificity by

68 Atf1-containing, bZIP protein dimers bind to CRE-like DNA sites, regulate

69 However, unlike bZIP proteins, DNA is not bent away from bHLH anionic ch

70 It also estimates relative bZIP protein duplication orders, using only interaction

71 maize (Zea mays L.) orthologue of the wheat bZIP protein EmBP-1 (mEmBP-1).

72 Here, we report that the K-bZIP protein encoded by Kaposi's sarcoma-associated herp

73 sidues that differ between Maf and canonical bZIP proteins facilitate the conformational change requi

74 other transcription factors, including some bZIP protein family members.

75 n, pX increases the DNA binding potential of bZip proteins for their cognate DNA-binding site in vitr

76 The bZIP proteins Fos and Jun bind DNA rapidly and with high

77 Recently described PAR-bZIP proteins from Drosophila and zebrafish also contain

78 Thus, the two bZip proteins function together as one of several inputs

79 ave isolated a soybean cDNA encoding a novel bZIP protein, G/HBF-1, which binds to both the G-box and

80 onal repressor, is negatively regulated by a bZip protein, gadd153/Chop10.

81 he DNA binding (basic) region from the plant bZIP protein GBF-1 (GBF) and a leucine zipper (F) design

82 We have developed a bZIP protein, GBF-F, with both dominant-negative (DN) an

83 pha-helical recognition epitope found on the bZIP protein GCN4 and binds DNA with nanomolar affinity

84 We have found that the bZip protein GCN4 can also bind with high affinity to DN

85 DNA major-groove binding, as occurs for the bZIP protein GCN4, perturbs the Raman signature of DNA o

86 tion of O2 and OHP1 contrasts with the maize bZIP protein gene OBF1, which lacks introns, suggesting

87 ctivation transactivator Rta and A6-encoding bZIP protein genes.

88 Here we show that the bZIP protein HapX functions as a key regulator of iron h

89 The c-Myc HLH-bZIP protein has been implicated in physiological or pat

90 mediates homo- or hetero-dimerization of the bZIP proteins has been intensively studied, and a variet

91 e oncogenes, meq (MDV Eco Q) which encodes a bZIP protein, has been biochemically characterized as a

92 interacting protein 1 (VIP1), an Arabidopsis bZIP protein, has been suggested to mediate transformati

93 ox elements specific for the EmBP-1 class of bZIP proteins have an important developmental function i

94 Two major subgroups among the plant bZIP proteins have been identified as G-box (CCACGTGG) o

95 Whereas the bZIP proteins, HY5 (elongated hypocotyl 5) and HYH (HY5

96 Here we identify a novel bZIP protein HYH, as a new target of COP1.

97 e zipper (CNC-bZIP) family is a subfamily of bZIP proteins identified from independent searches for f

98 nvestigate the in vivo role of this chimeric bZIP protein in oncogenic transformation, its expression

99 nstrate that ORF57 interacts with the KSHV K-bZIP protein in vitro and in cell extracts from lyticall

100 ctions increase the DNA affinities of target bZIP proteins in a DNA sequence-dependent manner.

101 etry studies with equimolar mixture of three bZIP proteins in pairs showed no heterodimer formation w

102 ates DNA-binding activities of this class of bZip proteins in transgenic tobacco plants.

103 Expression of the bZIP proteins in transgenic tobacco under control of the

104 as been observed for the small MAF family of bZIP proteins in vertebrates.

105 for efficient transcriptional activation by bZIP proteins in vivo.

106 The interaction of NPR1 with the rice bZIP proteins in yeast was impaired by the npr1-1 and np

107 a conserved family of basic-leucine-zipper (bZip) proteins in plants, have suggested a role for thes

108 ctor CHOP (C/EBP homologous protein 10) is a bZIP protein induced by a variety of stimuli that evoke

109 CHOP-10 (GADD153/DDIT-3) is a bZIP protein involved in differentiation and apoptosis.

110 el Hog1-dependent activator(s) that is not a bZIP protein is required for ATF/CREB site activation in

111 or 2 (ATF2) heterodimerization with specific bZIP proteins is an important determinant of the ubiquit

112 monstrated that binding specificity of plant bZIP proteins is determined independently by two regions

113 Selectivity of Chameau and MBF1 for bZIP proteins is mediated by residues in the basic regio

114 EB subfamily of basic-region leucine zipper (bZIP) proteins, is induced in response to endoplasmic re

115 mechanisms of transformation by the related bZIP proteins Jun and Fos that address the same target s

116 sly identified a small basic leucine zipper (bZIP) protein, Jun dimerization protein 2 (JDP-2), that

117 ) have been identified and a virally encoded bZip protein, K8, has been shown to specifically bind to

118 on to VP16, HCF-1 associates with a cellular bZIP protein known as LZIP (or Luman).

119 ingle high-affinity binding site for the Maf bZIP protein Krml1, encoded by the kreisler gene.

120 e globular bHLH domain which, in contrast to bZIP proteins, makes extensive DNA contacts along the bi

121 ation of heterodimers between Nrf2 and other bZIP proteins may simultaneously mask the NES and attenu

122 MDV encodes a basic leucine zipper (bZIP) protein, Meq (MDV EcoQ).

123 The basic region-leucine zipper (B-ZIP) (bZIP) protein motif dimerizes to bind specific DNA seque

124 In addition, a virally encoded bZip protein, namely K8, was found to bind to a DNA sequ

125 Basic leucine zipper (bZIP) protein Nrf2 is a key transcription factor mediati

126 similar function may be attributed to other bZIP proteins of the large Maf family.

127 e (TGAGTCA) for basic region-leucine zipper (bZIP) proteins of the AP-1-CREB superfamily.

128 In addition to the bZIP protein Opaque2 (O2), there are other maize endospe

129 characterization exists on this subclass of bZIP proteins, our work represents the first report of a

130 e found that the hematopoietic cell-specific bZip protein p45/NF-E2 interacts with T3 receptor (TR) a

131 In vitro, the Antirrinum bZIP proteins preferentially bind to a novel hybrid C-bo

132 B-binding site, supporting a model where the bZIP protein primarily functions to augment the activity

133 get genes were observed, indicating that the bZIP proteins probably interact with other factors to mo

134 -2, to stabilize the mRNA encoding CEBP-1, a bZip protein related to CCAAT/enhancer-binding proteins,

135 Basic region leucine zipper (bZIP) proteins represent a class of transcription factor

136 ramework for a novel mechanism through which bZIP proteins repress transcription.

137 Previous studies demonstrated that the bZIP protein RF2a is involved in transcriptional regulat

138 ated a cDNA encoding a basic leucine zipper (bZIP) protein, RF2a, which binds to the Box II cis eleme

139 and functional characterization of a second bZIP protein, RF2b.

140 The bZIP proteins share strong sequence and structural simil

141 This result reduces the concern that bZIP protein structure causes electrophoretic anomalies

142 The fact that TaFT2 interacts with another bZIP protein TaFDL13, which lacks the ability to interac

143 signals promoting flowering, interacts with bZIP proteins TaFDL2 and TaFDL6.

144 ect interactions in vitro between pX and the bZip proteins tested.

145 ed three independent cDNAs encoding ATF-2, a bZIP protein that binds cAMP response elements (CRE).

146 NFIL3, a growth factor-regulated bZIP protein that binds to the same DNA-consensus site a

147 virus (EBV)-encoded lytic activator Zta is a bZIP protein that can stimulate nucleosomal histone acet

148 ization protein 2 (JDP2) was identified as a bZIP protein that forms dimers with Jun proteins.

149 Bach-1 is a bZip protein that forms heterodimers with small Maf prot

150 ers of a novel and fungus-specific family of bZIP proteins that is defined by four atypical residues

151 F comprise a distinct subfamily of mammalian bZIP proteins that plays an important role in regulation

152 an MAFG gene encodes a basic-leucine zipper (bZIP) protein that belongs to a family of transcription

153 virus (KSHV) encodes a basic leucine zipper (bZip) protein that binds to the origin of viral DNA repl

154 ene codes for a basic region-leucine zipper (bZIP) protein that is disrupted by chromosomal transloca

155 rs are atypical basic region-leucine zipper (bZIP) proteins that contain a variant basic region and a

156 ortant group of basic region leucine zipper (bZIP) proteins that display high affinity for the CRE si

157 In all naturally occurring bZip proteins, the basic region is positioned N-terminal

158 cluded alteration of thyroid hormone induced bZip protein (thibz), deiodinases (dio2, dio3), thyroid

159 This makes MEQ the first bZIP protein to be identified in the nucleoli.

160 absence of its activation domains, recruits bZIP proteins to canonical NFAT-bZIP composite DNA eleme

161 on domain, continues to stimulate binding of bZip proteins to DNA.

162 rotein, c-Maf belongs to a family of related bZip proteins together with MafA and MafB.

163 oncogenic retrovirus AS42 encodes a nuclear bZip protein, v-Maf, that recognizes sequences related t

164 a specific coactivator for the AP-1 class of bZIP proteins via two arginine residues.

165 uggested a role for monomeric DNA binding by bZip proteins, we investigated the structure of the GCN4

166 ns, in which leucine zippers from bHLHZIP or bZIP proteins were fused to heterologous bHLH domains, a

167 etylases interact with distinct subgroups of bZIP proteins, whereas pX does not discriminate.

168 or transcripts encodes MEQ, a 339-amino-acid bZIP protein which is homologous to the Jun/Fos family o

169 w them to belong to a distinct sub-family of bZIP proteins which also includes LIP19 from rice and ML

170 large group of basic region-leucine zipper (bZip) proteins which was originally defined in the late

171 c region like those of basic-leucine zipper (bZIP) proteins, which bind DNA only as dimers.

172 large group of basic-region leucine zipper (bZIP) proteins whose members mediate diverse transcripti

173 gulation of the Pap1 transcription factor, a bZip protein with structural and DNA binding similaritie

174 e osZIP-2 factors represent a novel class of bZIP proteins with an unusual DNA-binding domain that do

175 related to members of the ATF/CREB family of bZIP proteins, with highest homology to ATF-4.

176 ted worms was associated with failure of the bZIP protein, ZC376.7, to localize to nuclei in worms wi