ライフサイエンスコーパス: bacitracin

1 ell wall-active agents (e.g., vancomycin and bacitracin).

2 the genes encoding pilus in the presence of bacitracin.

3 The latter clone exhibited resistance to bacitracin.

4 d by p-chloromercuribenzenesulfonic acid and bacitracin.

5 enged with the lipid II cycle-inhibiting AMP bacitracin.

6 d by other nephrotoxicants such as CdCl2 and bacitracin.

7 action, which was found to be independent of bacitracin.

8 a-PG and Lys-PG and increased sensitivity to bacitracin.

9 , such as vancomycin, ramoplanin, nisin, and bacitracin.

10 ol of sigmaX and sigmaM, was also induced by bacitracin.

11 train had an eightfold-higher sensitivity to bacitracin.

12 verine (20 microM), methylamine (20 mM), and bacitracin (2 mg/ml) prevented cell pair formation even

13 tal-binding amino acids of angiotensin I and bacitracin A are oxidized, while no oxidation is observe

14 te of bacitracin A with (1)O2 decreased upon bacitracin A coordination with Zn(2+), demonstrating tha

15 Furthermore, the photooxidation rate of bacitracin A with (1)O2 decreased upon bacitracin A coor

16 lly shifted (1)H NMR features concludes that bacitracin A(1), the most potent component of the bacitr

17 by (1)O2 is a major degradation pathway for bacitracin A, the most potent congener of the mixture.

18 crystal structure for the ternary complex of bacitracin A, zinc, and a geranyl-pyrophosphate ligand a

19 high-potent bacitracin analogues, including bacitracins A(1), B(1), and B(2), are virtually identica

20 es with low antibiotic activities, including bacitracins A(2) and F.

21 shedding induced by PDI-blocking Abs and by bacitracin, a known inhibitor of PDI activity, and direc

22 Despite the wide use of bacitracin, a structure-activity relationship for this d

23 thesis, leads to an increased sensitivity to bacitracin, an antibiotic that binds undecaprenyl pyroph

24 report the response of Bacillus subtilis to bacitracin, an inhibitor of cell wall biosynthesis found

25 Bacitracin, an inhibitor of plasma membrane oxidoreducta

26 Bacitracin, an inhibitor of the reductive function of th

27 structure of the metal complexes of several bacitracin analogues by the use of paramagnetic Co(II) a

28 thiazoline ring does not bind Co(II) in the bacitracin analogues with low antibiotic activities, inc

29 1)H NMR spectral features of the high-potent bacitracin analogues, including bacitracins A(1), B(1),

30 boxylation is inhibited by the PDI inhibitor bacitracin and also by small interfering RNA silencing o

31 ant was also significantly more sensitive to bacitracin and lysozyme than the wild type in in vitro c

32 mutans streptococci (MS) on mitis-salivarius-bacitracin and mitis-salivarius agar; (2) non-mutans str

33 In the presence of extracellular bacitracin and nisin, respectively, the two response reg

34 cell wall biosynthesis such as moenomycin A, bacitracin and ramoplanin were not inducers of the S. co

35 By comparing the bacitracin and the vancomycin stimulons, we can differen

36 entiate between loci induced specifically by bacitracin and those that are induced by multiple cell w

37 s that were fed chlortetracyline, tylosin or bacitracin and were land applied via broadcast, incorpor

38 ies have addressed the environmental fate of bacitracin and zinc-bacitracin complexes.

39 y limit the clinical use of fusidic acid and bacitracin and, possibly, rifaximin if resistance to thi

40 owing exposure to the antimicrobial peptides bacitracin and/or lysozyme.

41 (5,5'-dithiobis[2-nitrobenzoic acid]), (ii) bacitracin, and (iii) anti-PDI antibodies--resulted in r

42 -5'5-dithio-bis(2-nitrobenzoic acid) (DTNB), bacitracin, and anti-protein disulfide isomerase antibod

43 ar and OF basal medium with agar, polymyxin, bacitracin, and lactose) and by plating on antibiotic-co

44 to target genes that are strongly induced by bacitracin, and the corresponding histidine kinases shar

45 The peptidyl antibiotic bacitracin (Bc) is one of the most widely used antibioti

46 esistance to antibiotics such as acriflavin, bacitracin, bleomycin, daunorubicin, florfenicol, and ot

47 The inhibitors DTNB and bacitracin blocked the detection of these free thiols.

48 elerated factor Xa generation was blocked by bacitracin but not influenced by inhibition of vicinal t

49 bility was also increased to cycloserine and bacitracin, but not to fosfomycin or valinomycin; these

50 Direct and specific binding of bacitracin by BceB was demonstrated by surface plasmon r

51 d to a model in which BceAB protects against bacitracin by transfer of the target, C55 -PP, rather th

52 Bacitracin caused an unusual time-dependent opposing eff

53 tomy-tube otorrhea to receive hydrocortisone-bacitracin-colistin eardrops (76 children) or oral amoxi

54 ficantly higher sensitivity of the mutant to bacitracin compared with that of the parental strain.

55 ant and a yvcK mutant were more sensitive to bacitracin compared with the WT strain.

56 he environmental fate of bacitracin and zinc-bacitracin complexes.

57 s study, the photochemical transformation of bacitracin components (i.e., cyclic dodecapeptides) in t

58 ese results provide insight into the fate of bacitracin components in the aquatic environment and hig

59 ochemical degradation kinetics of individual bacitracin components, investigation of the relative con

60 peptides (vancomycin, ristocetin), peptides (bacitracin, cycloserine), and chloramphenicol were found

61 ioactive such as the antibiotics vancomycin, bacitracin, daptomycin and the beta-lactam-containing pe

62 COL2525 protein showed 87% homology with the bacitracin drug transporter BcrA of Staphylococcus homin

63 e synthesis of antibiotics of the gramicidin/bacitracin family; however, no bacteriophage genomes are

64 he white petrolatum group vs 4 (0.9%) in the bacitracin group (95% confidence interval for difference

65 due to Staphylococcus aureus vs none in the bacitracin group (P=.004).

66 in the white petrolatum group and 444 in the bacitracin group were evaluable for clinical response.

67 Bacitracin had no deleterious effect on HPV16 entry, cap

68 in the endosomal penetration of L2/vDNA, but bacitracin had no effect on gamma-secretase activity, in

69 Several different analogues of bacitracin have also been isolated or prepared, and the

70 IDE inhibition by bacitracin impaired amylin degradation, increased amyloi

71 Inhibition of PDI using bacitracin increased aggregate production, even in wild

72 Bacitracin induced expression of bcrC, and this inductio

73 A systematic mutational analysis of bacitracin-induced genes led to the identification of a

74 sO transcription unit was under control of a bacitracin-inducible promoter.

75 The IDE inhibitor bacitracin inhibited amylin degradation by 78% and insul

76 le IDE protein extracted from liver, or with bacitracin inhibited VZV infection.

77 Bacitracin is a metalloantibiotic agent that is widely u

78 Bacitracin is a mixture of nonribosomal peptides (NRPs)

79 Bacitracin is a widely used metal-dependent peptide anti

80 bition by dansylcadaverine, methylamine, and bacitracin is not due to an alkalinization of the lysoso

81 ing those that confer resistance to cadmium, bacitracin, macrolides, penicillin, kanamycin, and strep

82 racin A(1), the most potent component of the bacitracin mixture, binds to Co(II) via the His-10 imida

83 The compensatory regulation within the bacitracin network can also explain how gene expression

84 e effects of the commonly used PDI inhibitor bacitracin on HPV16 infection.

85 Infusion of the PDI inhibitor bacitracin or a blocking monoclonal antibody against PDI

86 bitors of protein disulfide isomerase (PDI), bacitracin or antibodies to PDI.

87 ited by p-chloromercuribenzenesulfonic acid, bacitracin, or anti-PDI antibodies, these inhibitors had

88 sms, the BcrABC transporter, which pumps out bacitracin, or BacA, an undecaprenol kinase that provide

89 itis vs 4 patients (0.9%) in the group using bacitracin (P=.12).

90 identification of oxidative modifications in bacitracin photoproducts.

91 antibiotics), and three peptide antibiotics (bacitracin, polymyxin B, and vancomycin).

92 eptide antibiotics (gramicidin, actinomycin, bacitracin, polymyxins).

93 citracin transport permease, is an important bacitracin resistance determinant.

94 The bcrC bacitracin resistance gene, which is under the dual cont

95 Bacitracin resistance is normally conferred by either of

96 e suggest that this active redundancy in the bacitracin resistance network of B. subtilis is a genera

97 both YqjL, a putative hydrolase, and BcrC, a bacitracin resistance protein, were involved in PQ resis

98 signaling pathway in more detail, using the bacitracin resistance system BceRS-BceAB of Bacillus sub

99 ) and BceAB (an ABC transporter that confers bacitracin resistance).

100 This study reveals a direct role of LiaIH in bacitracin resistance, provides novel insights into the

101 AB) and secondary (BcrC and LiaIH) layers of bacitracin resistance.

102 ced genes led to the identification of a new bacitracin-resistance determinant, bceAB, encoding a put

103 n of undecaprenyl pyrophosphate recycling by bacitracin resulted in a similar decrease in the membran

104 Despite bacitracin's broad use, the molecular details of its tar

105 Bacitracin's efficient sequestration of its target repre

106 Genetic studies indicate that bacitracin sensitivity is due to accumulation of C35 -PP

107 In addition, the bacitracin sensitivity of strains in which YvcK Thr-304

108 Bacitracin sensitivity results from impairment of the Bc

109 utant disruption of ytpB no longer increases bacitracin sensitivity.

110 nthesis, including ramoplanin, moenomycin A, bacitracin, several glycopeptides and some beta-lactams.

111 was able to partially rescue the virus from bacitracin, suggesting the involvement of a cellular red

112 btilis bcrC (ywoA) gene, encoding a putative bacitracin transport permease, is an important bacitraci

113 sis of the global transcriptional profile of bacitracin-treated cells reveals a response orchestrated

114 Bacitracin treatment markedly increased staining at all

115 tidrug, macrolide-lincosamide-streptogramin, bacitracin, vancomycin, beta-lactam and aminoglycoside r

116 Bacitracin was rapidly taken up by host cells and coloca

117 for vancomycin, tunicamycin, flavomycin, and bacitracin were 1.1 microM, 0.01 microg/ml, 0.03 microg/

118 a sigM mutant was fourfold more sensitive to bacitracin, while the sigX mutant was only slightly sens

119 In comparison with bacitracin, white petrolatum possesses an equally low in

120 Bacitracin with amylin caused a dramatic decrease in cel