ライフサイエンスコーパス: backup

1 d that the SMUG1 glycosylase might provide a backup.

2 ays, allowing alt-EJ to function as rescuing-backup.

3 ersons cannot be recommended without culture backup.

4 U:dG lesion with uracil excision providing a backup.

5 at centers without on-site cardiac surgical backup.

6 linical events compared with PTCA with stent backup.

7 , and outputs can be archived for sharing or backup.

8 gesting combinatorial control or a molecular backup.

9 oly(ADP)ribose polymerase 1 (PARP1) serve as backups.

10 cantly different between the DDD arm and the backup AAI arm.

11 o either DDD pacing for 3 months followed by backup AAI pacing for 3 months, or the same study arms i

12 ed to 3 months each of DDD pacing and pacing backup (AAI-30) in a double-blind, crossover study desig

13 sence of Fpg and MutY, endo VIII serves as a backup activity to remove 8-oxoG.

14 posed that transcriptional reprogramming and backup among duplicates is a genomewide phenomenon in th

15 Surgical backup and acute management skills for treating tamponad

16 Decisions about energy backup and cooling options for parabolic trough (PT) con

17 aluation: syncope facilities with specialist backup and interactive decision-making software.

18 y emerge from the need for extensive modular backup and the requirement to integrate transcriptional

19 y Service tool for automated instrument file backup and the ScanSifter tool for data conversion.

20 Communication, backup, and emergency systems must be integrated, often

21 o had symptomatic improvement during the AAI backup arm.

22 cally arranged in hierarchies, with magnetic backup as a last resort when celestial information is un

23 oom, where the radiologist was available for backup as needed.

24 ng partner XRCC1, this interaction acts as a backup attempt to intercept the more error-prone alterna

25 ope localization, enhanced histopathology, a backup axillary dissection, and judicious case selection

26 lternative form of end joining, operating as backup (B-NHEJ) functions robustly throughout the cell c

27 alternative form of NHEJ that operates as a backup (B-NHEJ) to the DNA-PK-dependent (D-NHEJ) pathway

28 (HON1), XRCC1, and PARP1, participate in a 'backup' (b)NHEJ process.

29 ification of HCV NS3 inhibitors as potential backup candidates to our first generation drug candidate

30 Thus escl appears to function in a backup capacity during development that becomes importan

31 selected for further evaluation as potential backup compounds to 1.

32 ss was further explored, seeking efficacious backup compounds with improved solubility and safety.

33 (SC-77774), respectively, were identified as backup compounds.

34 Genomically encoded backup control circuitry thus provides the mechanism und

35 arios to identify the highest-scoring energy backup-cooling combination for each preference scenario.

36 as well as those devices with defibrillator backup (CRT-D).

37 true disease status and obviate the need for backup cultures if specificity can be improved.

38 sis regulatory pathway and reiterated that a backup cytokinesis pathway is activated by inhibiting th

39 One enhancer acts as an inducible backup ('dark' shadow enhancer) that is normally repress

40 ty for monoubiquitinated APE1 and because of backup E3 ligases in the cells.

41 adult dogs in complete heart block and with backup electronic pacemakers.

42 brinolytic system, serves as a physiological backup enzyme for ADAMTS13 in the degradation of patholo

43 raise the possibility that NEIL1 serves as a backup enzyme to APE1 in stimulating 8-oxoG repair in vi

44 f copper amine oxidase by a flavin-dependent backup enzyme.

45 hermal energy storage (TES), and fossil fuel backup (FF)) and different cooling options (wet (WC) and

46 6 (10a) was selected as a potential clinical backup for 1.

47 ation on endothelial cells acts as a natural backup for ADAMTS13 to degrade obstructive platelet-VWF

48 so suggested that BiP/GRP78 could serve as a backup for calnexin and calreticulin in retaining the fr

49 In the search of a potential backup for clopidogrel, we have initiated a HTS campaign

50 texposure treatment should be used only as a backup for failure of primary prevention methods, such a

51 erent Lon substrates and appears to act as a backup for Lon under certain conditions.

52 question the idea that p18(INK4c) acts as a backup for loss of p16(INK4a) and suggest that the appar

53 s conditions, providing both specificity and backup for protection from oxidative damage.

54 enge superoxide anion radicals and provide a backup for superoxide dismutase enzymes.

55 ytes, demonstrating that Synpo-T serves as a backup for Synpo-long in synpo(-/-) podocytes.

56 3'-->5' Exo of Pol delta as a supplement or backup for the Rad27/Fen1 5' flap endonuclease.

57 mU-excision in mice as well as the major UNG-backup for U-excision.

58 ) picking of surrogate tagSNPs that serve as backups for tagSNPs whose failure would result in a sign

59 ort and device programming who had immediate backup from an electrophysiologist.

60 placed by a bedside nursing-based team with backup from the Interventional Radiology department.

61 Yen1 serves a backup function responsible for resolving intermediates

62 e replicating strand, with NEIL2 providing a backup function.

63 54, and thus, H189 may be able to serve as a backup general base at a lower efficiency compared to H1

64 these variables, or waterproof protection of backup generators, could have mitigated or prevented the

65 a wall elevation, and location and status of backup generators.

66 We did not detect a backup glycosylase or glycosylase/AP lyase activity for

67 ow we plan for unit shipment and the role of backup grafts.

68 o be present downstream of genes to act as a backup in case of read-through of the real stop codon.

69 plicates are unlikely to provide substantial backup in the context of large natural populations.

70 These 'dormant' origins provide a backup in the presence of stalled forks and may confer f

71 mologous recombination provides an essential backup in vertebrate rad18 mutants, we show that in chic

72 on with PCT rather than switching to another backup IOL demanding wound enlargement.

73 eekend hours and how cardiovascular surgical backup is arranged.

74 performed at centers without onsite surgical backup is not associated with any mortality hazard.

75 or direct backup, the prevalence of indirect backup is poorly understood.

76 and land use suggest a preference for TES if backup is require for PT plants to compete with baseload

77 tion capabilities that can be recruited as a backup kinase for both gatekeeper tumor suppression and

78 Reliance on the backup ligase is accompanied by a drastic loss of fideli

79 However, preparation of backup liver transplantation should be considered in sel

80 In search of a backup M(2) muscarinic receptor antagonist to the previo

81 engrafted without infusion of unmanipulated "backup" marrow (n = 14).

82 of PT with different backup options (minimal backup (MB), thermal energy storage (TES), and fossil fu

83 roliferating cell nuclear antigen provides a backup mechanism for accurate bypass of these sequences

84 d1 provides the intestinal epithelium with a backup mechanism for rapidly activating innate immunity

85 and stochastically, revealing a first-order backup mechanism for rhodopsin deactivation.

86 We propose that this backup mechanism may be a general feature of endocrine r

87 equate rate of cycling and likely provides a backup mechanism to enable polymerase release when the o

88 s may employ stress-related suppression as a backup mechanism to guard against lapses in reproductive

89 ar movement into the neck and can serve as a backup mechanism to move the nucleus into the neck when

90 e presence of RAP1 at telomeres appears as a backup mechanism to prevent NHEJ when topology-mediated

91 In this backup mechanism, strong ligand-receptor binding between

92 t role in cell division, although cells have backup mechanisms for dividing if centrioles are missing

93 rnative cell death mechanisms as primary and backup mechanisms is discussed.

94 sts (RADTs) do not require confirmation by a backup method in adults, whereas laboratory-based guidel

95 replicative polymerases, and the presence of backup Mg(2+)-dependent endonuclease activity in early s

96 0.2 to 0.7), the patient's device reset to a backup mode.

97 rium tuberculosis LigC can also support this backup NHEJ pathway.

98 sion repair, single strand break repair, and backup nonhomologous end-joining pathway.

99 Albeit not excluding the agency of a backup nuclease, our findings suggest that mycobacterial

100 cumulation of clathrin-coated vesicles and a backup of newly reformed vesicles in the cytomatrix-rich

101 sponsive pacing as compared with ventricular backup-only pacing worsens the combined end point of mor

102 ly worse than, and was likely equivalent to, backup-only ventricular pacing.

103 ial pacing is a safe alternative to minimal (backup-only) ventricular pacing in defibrillator recipie

104 ed independently and can be used either for "backup" operation or for parallel operation with other m

105 use gas (GHG) emissions of PT with different backup options (minimal backup (MB), thermal energy stor

106 recent years, energy policies do not address backup or cooling option requirements, and very few stud

107 arise either due to redundancy, i.e. direct backup, or due to distributed architecture, i.e. indirec

108 The AVJ is a primary backup pacemaker to the sinoatrial node.

109 ve pacing (dual-chamber pacing at 70 bpm) or backup pacing (atrial pacing at 30 bpm).

110 e pacing and in 27 of 41 (66%) randomized to backup pacing (control), yielding a hazard ratio of 0.25

111 ffers no clinical advantage over ventricular backup pacing and may be detrimental by increasing the c

112 d to have the ICDs programmed to ventricular backup pacing at 40/min (VVI-40; n = 256) or dual-chambe

113 with a lower rate of 60 ppm is compared with backup pacing at DDI with a lower rate of 30 ppm.

114 00 microg/900 microg) and was supported with backup pacing when needed.

115 130 beats/min), no dependence on electronic backup pacing, and enhanced modulation of pacemaker func

116 associated with similar outcomes as with VVI backup pacing.

117 160 beats/min, and low to absent electronic backup pacing.

118 e, escape time, and dependence on electronic backup pacing.

119 NHEJ-deficient cells via a poorly understand backup pathway (or pathways) often termed alternative en

120 The backup pathway creates a threshold such that ATRi select

121 use of nucleotide excision repair (NER) as a backup pathway for RER in RNase HII-deficient cells and

122 Our data indicate that the backup pathway that normally ensures proper segregation

123 that nucleotide incision repair may act as a backup pathway to base excision repair to remove uracils

124 sDNA and triggers a DNA-PK and Chk1-mediated backup pathway to suppress origin firing.

125 vage, and is stimulated by components of the backup pathway.

126 r; P=0.01), a caregiver who has identified a backup plan (P=0.02), and a caregiver who is able to pro

127 -line stabilization, cricoid pressure, and a backup plan for a surgical airway is still the most effi

128 e results suggest that Rev1 could serve as a backup polymerase in BER and could potentially contribut

129 its absence, cells do not have an efficient backup polymerase or a repair/tolerance mechanism facili

130 ld be greatly enhanced if fully operational, backup power systems were mandated, not only for acute c

131 rticularly in the G2-phase and is thought to backup predominantly D-NHEJ.

132 e may reflect motivations to use condoms for backup pregnancy prevention.

133 As part of a backup program around this scaffold, we explored heteroa

134 Within a backup program for the clinical investigational agent pr

135 initially studied for tuberculosis within a backup program for the clinical trial agent pretomanid (

136 ntigenic stimulation, providing nonredundant backup protection for the host when granzyme B fails.

137 ypocapnia, which combined with the lack of a backup rate and wakefulness drive can lead to central ap

138 irway pressure of 4 (IQR, 4-5) cm H2O, and a backup rate of 14 (IQR, 14-16) breaths/minute.

139 jects, we examined whether the presence of a backup rate on assist-control ventilation would decrease

140 model is consistent with PPAT serving as a "backup" regulator of pathway flux relative to pantothena

141 ng (alt-NHEJ) was originally identified as a backup repair mechanism in the absence of classical NHEJ

142 hese studies suggest that MMEJ not only is a backup repair pathway in mammalian cells, but also has i

143 s such as hybrid electric vehicles and power backup require rechargeable batteries that combine high

144 e glutaredoxin system and glutathione have a backup role to keep Trx1 reduced in cells with loss of T

145 Thus, thymine DNA glycosylase may play a backup role to the more efficient general uracil DNA gly

146 xidative stress genes whereas SpxA2 served a backup role.

147 resistance generally develops, necessitating backup strategies for therapy.

148 such as redundancy, node recovery time, and backup supply available.

149 The two proteins also form a backup system for engulfment.

150 progenitor cells do not function solely as a backup system in chronic liver injury; rather, they also

151 Thus, an "over-engineered" backup system in the form of distributed architecture is

152 We hypothesized that there should exist a backup system to reduce Trx1 when only TrxR1 activity wa

153 hereas the error-free pathway functions as a backup system.

154 these heterologous elements may represent a "backup" system capable of catalyzing P-choline incorpora

155 oxins and glutathione peroxidases with their backup systems as well as by catalase.

156 ssion activities do not function as cryptic 'backup' systems, but that each contributes quantitativel

157 both the SRP and GET pathways, and act as a backup targeting system.

158 for GAS have relatively low sensitivity, and backup testing is recommended in children.

159 sting method for GAS pharyngitis and obviate backup testing on negative results.

160 Despite clear evidence for direct backup, the prevalence of indirect backup is poorly unde

161 th mismatch recognition of dU:dG providing a backup; the second phase of hypermutation (essentially i

162 ipt cleavage accompanied significant RNAP II backup, thereby providing access of the repair enzyme to

163 de that combines patient flow-triggering and backup time-triggering.

164 Seventh, surveillance requires laboratory backup to confirm a diagnosis.

165 more, CXCR4-Lo may also provide a functional backup to CXCR4 during embryogenesis.

166 ressed copy and the plasmid operon acts as a backup to maintain appropriate gene dosages.

167 e Holliday junction but acts as an essential backup to MUS81 for resolution of toxic replication stru

168 test can be used as the primary test or as a backup to negative antigen tests.

169 egulation of E2F1 and may serve as a partial backup to prevent E2F1-mediated apoptosis in the absence

170 this signaling can indeed act as a redundant backup to the exogenous gradient, it introduces a positi

171 etic toxicity issues and was considered as a backup to vilanterol.

172 with therapeutic tactics serving strictly as backups to these natural regulators.

173 heir therapeutic or recreational use because backup transporters and alterations in receptor gene exp

174 Laser therapy may still be required as a backup treatment for patients who do not respond to an I

175 There is an urgent need for backup treatment options for patients with cephalosporin

176 We present the Backup Utility Service tool for automated instrument fil

177 ardioverter defibrillator (ICD) therapy with backup ventricular pacing increases survival in patients

178 re, depending on how cardiovascular surgical backup was provided.

179 hnical personnel and cardiovascular surgical backup were already covered.

180 e to distributed architecture, i.e. indirect backup where multiple genes contribute to the functionin