ライフサイエンスコーパス: bacterial load

1 further phagocytosis, resulting in elevated bacterial load.

2 Cytobrushes collected a higher total bacterial load.

3 of neutrophils induced an increased mammary bacterial load.

4 rier rather than a response to the increased bacterial load.

5 on, organ damage, immune cell apoptosis, and bacterial load.

6 MAITs migrated to the bladder and decreased bacterial load.

7 orly in specimens having a low volume or low bacterial load.

8 +) T cell trafficking to the uterus and high bacterial load.

9 in male mice and was associated with greater bacterial load.

10 mic inflammation with a gradually increasing bacterial load.

11 ects of antimicrobial on milk microbiome and bacterial load.

12 and elafin levels correlated inversely with bacterial load.

13 recruitment in granulomas, and decreased the bacterial load.

14 s not associated with GER, salivary flow, or bacterial load.

15 ly assessed together by determination of net bacterial load.

16 -/- mice showed a dramatic increase in renal bacterial load.

17 decreased production of IL-10 and a reduced bacterial load.

18 nergizes with noncognate T cells to restrict bacterial load.

19 amma production by T cells, and an increased bacterial load.

20 eriological cure, pathogen clearance rate or bacterial load.

21 yo excision to determine the location of the bacterial load.

22 rier rather than a response to the increased bacterial load.

23 emic animals reduced both airway glucose and bacterial load.

24 h defective microbial clearance and elevated bacterial load.

25 ology without affecting pendrin synthesis or bacterial loads.

26 yte recruitment and a subsequent decrease in bacterial loads.

27 ion, with Il10(-/-) mice having reduced lung bacterial loads.

28 cell activation, accompanied with increased bacterial loads.

29 suggesting that tumor sizes affected optimal bacterial loads.

30 uthanasia and vitreous harvest to quantitate bacterial loads.

31 nd found a 5- to 10-fold decrease in gastric bacterial loads.

32 caused by hyperglycaemia leads to increased bacterial loads.

33 in neutropenic patients transfused with high bacterial loads.

34 infections as well as the characteristics of bacterial loads.

35 ation was apparent even in animals with high bacterial loads (10(5) to 10(6) CFU).

36 Efficacy was determined by a reduction in bacterial load 4 weeks after challenge.

37 for every 1 log(10) increase in pretreatment bacterial load (95% CI, 1.53 to 8.59).

38 t aggressive treatment produces the greatest bacterial load, a fortiori greater than if just one drug

39 ly dependent on parameter values and initial bacterial load, a significant common trend is identified

40 gh)) to distinguish effects caused by higher bacterial loads achieved in WT infection from effects as

41 dietary fat composition affect survival and bacterial load after experimental septic infection and n

42 reatments were associated with reductions in bacterial load, airways, and systemic inflammation.

43 The relationship between bacterial load and airway and systemic inflammation was

44 c mice showed increased skin lesion size and bacterial load and decreased PGE2 secretion and Th17 cel

45 apable of the rapid, real-time assessment of bacterial load and diversity.

46 Furthermore, miR-263a mutants have increased bacterial load and expression of antimicrobial peptides.

47 ated in immune-compromised flies with higher bacterial load and gut cell death.

48 early information on the rate of decline in bacterial load and has technical advantages over culture

49 ne was amplified, allowing quantification of bacterial load and identification of communities by 16S

50 Quantitative PCR was used to compare bacterial load and Illumina MiSeq sequencing of the V1-V

51 d with immune response phenotypes, including bacterial load and immune gene expression.

52 rivatives increases the survival and reduces bacterial load and inflammation in mice with polymicrobi

53 a alginate (BC7/alginate), and the pulmonary bacterial load and inflammation were monitored.

54 This is correlated with a reduced bacterial load and inflammatory response in these mice.

55 ere was a direct relationship between airway bacterial load and markers of airway inflammation (P < 0

56 er mortality in LPS-treated mice but a lower bacterial load and mortality in mice with Pseudomonas ae

57 during murine enteric infection by reducing bacterial load and preventing systemic dissemination of

58 Milk from the mastitic quarter had a higher bacterial load and reduced microbial diversity compared

59 l and fluoride therapy significantly reduced bacterial load and suggested reduced caries increment in

60 Ebselen 1% and 2% significantly reduced the bacterial load and the levels of the pro-inflammatory cy

61 R12 and D-IK8 significantly reduced both the bacterial load and the levels of the pro-inflammatory cy

62 in contact with neonates decreased the total bacterial load and the percentage of Streptococcus speci

63 nts, there was a direct relationship between bacterial load and the risk of subsequent exacerbations

64 more severe lung histopathology for similar bacterial loads and died significantly earlier than did

65 G-infected Atg7(-)/(-) mice showed increased bacterial loads and exacerbated lung inflammatory respon

66 t mice exhibited significantly lower bladder bacterial loads and fewer intracellular bacterial commun

67 IF immunoglogulin G (IgG) antibodies reduced bacterial loads and improved survival in a mouse model o

68 Bacterial loads and inflammatory responses were similar

69 e to tuberculosis, as demonstrated by higher bacterial loads and less robust inflammatory responses i

70 t CD4 T cells themselves drive the increased bacterial loads and pathology seen in infected PD-1 KO m

71 of IgA resulted in a significant increase in bacterial loads and reduced survival.

72 ent mice induces hypoferremia that decreases bacterial loads and rescues these mice from death, regar

73 showed increased weight and survival, lower bacterial load, and attenuated intestinal pathology comp

74 Dietary intake, oral hygiene, high bacterial load, and decreased salivary flow might contri

75 ewer recruited leukocytes, reduced pulmonary bacterial load, and enhanced animal survival.

76 total weight loss, differential cell counts, bacterial load, and intraacinar airspace/tissue volume w

77 ng after the ulcerative phase despite stable bacterial load, and mycolactone toxin was not detected i

78 e improves survival and decreases peritoneal bacterial loads, and CXCL10 increases mouse and human ne

79 ciated with invasive pneumococcal pneumonia, bacterial loads, and death.

80 Differences in mortality and bacterial load are due to injury of the thorax and can b

81 ens produced a more rapid initial decline in bacterial load, as compared with the control group.

82 es do not "preserve" the carcass by reducing bacterial load, as is commonly supposed.

83 tion with MntC was effective at reducing the bacterial load associated with S. aureus and S. epidermi

84 ored and the phenoloxidase (PO) response and bacterial load at 24-hr postinfection were ascertained.

85 gative correlation between nitrite and total bacterial load at 6 months (FMS + CHX) and one positive

86 monitored quantitatively by determining the bacterial loads at different times post-infection.

87 ort that MAIT cell-deficient mice had higher bacterial loads at early times after infection compared

88 effector responses are associated with lower bacterial loads at the expense of gastric pathology.

89 peri-implant sulcus but significantly lower bacterial loads at the inner portion of the implant conn

90 ity to colonize mouse stomachs (9-fold-lower bacterial load) at 9 weeks postinoculation.

91 hase of sepsis, decreased local and systemic bacterial load, attenuated cytokine production, and redu

92 While baseline levels of total bacterial load, Bacteroidetes, Firmicutes, and Enterobac

93 floxacin treatment were sufficient to reduce bacterial loads below detectable levels in all major org

94 e attributed to differences in IgA levels or bacterial load between the 2 groups.

95 erficial epithelial layer acts to reduce the bacterial load but facilitates chronic residence of smal

96 NLRP3 inhibitor-treated mice displayed lower bacterial load but no impairment in neutrophil recruitme

97 Depletion of NK cells led to higher bacterial loads but less severe colonic inflammation, as

98 n (determined by myeloperoxidase assay), and bacterial load, but it diminished PMN bactericidal activ

99 lls postinjection, such as induced by higher bacterial loads, but in the longer term did not correlat

100 mg/kg (15.6 mumol/kg) conjugate reduced the bacterial load by 99% and demonstrated nearly an order o

101 However, reducing the bacterial load by antibiotic treatment or breeding mice

102 However, reducing the bacterial load by antibiotic treatment or breeding mice

103 ants generate fewer abscesses with a reduced bacterial load compared to wild-type parent strain Newma

104 symptoms, and whether salivary flow rate or bacterial load contribute to location-specific dental er

105 H. pylori bacterial load correlated positively with intensity of O

106 red and infected mice was increased and lung bacterial load decreased by airway leptin administration

107 ally led to enhanced protection with reduced bacterial load, decreased chemokine expression, and redu

108 Notably, increasing bacterial loads did not necessarily produce better long-

109 ucose as a critical determinant of increased bacterial load during diabetes.

110 8 weeks had increased survival and decreased bacterial load during sepsis compared with mice fed a sa

111 L-10, showed a significant reduction in lung bacterial loads during chronic M. tuberculosis infection

112 ajor importance for the accumulation of high bacterial loads during infection of the urinary tract.

113 nged the bleeding time, it did not impact on bacterial loads during pneumococcal pneumonia.

114 ithelial cells had significantly higher lung bacterial loads, enhanced mortality, decreased caspase a

115 um) causes acute, fatal bacteremia with high bacterial load, features reproduced by phenylhydrazine-i

116 ough its action on potential mediators (oral bacterial load, fluoride levels, and overall caries risk

117 ted with anti-CD71 Ab showed reduced splenic bacterial load following bacterial challenge compared wi

118 ecific integrins on cellular recruitment and bacterial loads following pneumococcal infection.

119 say responds rapidly, with a mean decline in bacterial load for 111 subjects of 0.99 log(10) (95% con

120 Prevalence of positive sites and bacterial loads for 10 microorganisms were obtained with

121 However, diazepam increased mortality and bacterial load from S. pneumoniae pneumonia.

122 The ability to clear the bacterial load from the lung remained preserved in sham

123 Despite higher bacterial loads, GPVI-depleted mice showed reduced plate

124 lar cell adhesion molecule-1 (P < 0.05 above bacterial load >/=1 x 10(7) cfu/ml).

125 Bacterial load, histology, cellular distribution, cytoki

126 We found no difference in bacterial load, histopathology, or host mortality betwee

127 The bacterial load in all organs significantly correlated wi

128 on to the spleen with a trend toward reduced bacterial load in blood and liver.

129 per L) concentrations reduced the pathogenic bacterial load in broth culture by 2 to over 6 logs depe

130 o detrimental impacts on milk microbiome and bacterial load in cows with a healthy mammary gland.

131 contaminated health care workers (HCWs), and bacterial load in environment.

132 irulent ST2 strain NCTC 7466 by reducing the bacterial load in lung tissue and blood.

133 6), more neutrophil recruitment, and a lower bacterial load in lung tissue than mice infected with wi

134 an acute pneumonia with a rapid decrease of bacterial load in lungs and with an increase of endothel

135 ow thoracic lesions, significantly increased bacterial load in lungs.

136 either novel heteroglycan or the LTA reduced bacterial load in mouse liver or kidney tissue.

137 emic infection and significantly reduces the bacterial load in murine organs including the spleen and

138 ptible DBA/2J (D) mice but a higher terminal bacterial load in resistant BALB/cJ (C) mice.

139 The bacterial load in serum/blood ranged from 10(2) to 10(6)

140 significantly enhanced survival and reduced bacterial load in several organs.

141 GC-C-/- mice had an increase in C. rodentium bacterial load in stool relative to GC-C+/+.

142 These effects may be achieved by reducing bacterial load in the airways in stable state and/or bro

143 tive in a mouse model of UTI by reducing the bacterial load in the bladder by about 1000-fold.

144 ed animals exhibited a significantly reduced bacterial load in the blood and other mouse organs, as w

145 n vivo functional activity by decreasing the bacterial load in the blood and tissues, with IgG2a and

146 our studies but significantly increases the bacterial load in the blood of infected animals.

147 ompound in reducing subsequent intracellular bacterial load in the corneal epithelium in a contact le

148 iling effect and a greater estimated fall in bacterial load in the higher dosing groups.

149 ect pathway contributed significantly to the bacterial load in the liver and was followed by a second

150 ry tract infections and did not increase the bacterial load in the livers of mice infected with the i

151 ) transgene was associated with an increased bacterial load in the lung but not increased mortality.

152 at poly(I:C) treatment significantly reduced bacterial load in the lungs (P < 0.05).

153 A-targeted carriers significantly diminished bacterial load in the lungs and caused recruitment of T

154 During the first 2 weeks after birth, the bacterial load in the lungs increased, and representatio

155 ipoLLA was able to kill H. pylori and reduce bacterial load in the mouse stomach.

156 increased inflammatory cell recruitment and bacterial load in the pleural cavity, and heightened lev

157 tological examinations, and determination of bacterial load in the retina.

158 e leptin receptor, have a markedly increased bacterial load in their lungs when compared with that of

159 porphyrin IX to mice resulted in an enhanced bacterial load in various organs and was associated with

160 causes a two-order-of-magnitude increase in bacterial loads in adults and a proliferation of the inf

161 d increased mortality associated with higher bacterial loads in blood, liver, and spleen.

162 oducing persistent infection with high titer bacterial loads in both the host (up to 10(5) colony-for

163 Salmonella, possessing significantly higher bacterial loads in both the spleen and the liver.

164 Hi phagocytosis and increased nasopharyngeal bacterial loads in ccl3(-/-) mice.

165 PCIH restricted mycobacterial growth at high bacterial loads in culture, a property not observed with

166 In contrast to the reduced bacterial loads in GRK5 KO mice following a sublethal do

167 combined treatment led to a decrease in the bacterial loads in infected organs.

168 remia model, as assessed on the basis of the bacterial loads in internal organs and overall lethality

169 ning of infection, as indicated by increased bacterial loads in kidneys and lungs, accelerated mortal

170 eminated to all tissues tested with greatest bacterial loads in lungs, but also spleen, lymph nodes,

171 p = 0.003), which was associated with higher bacterial loads in lungs, spleen, and blood.

172 The bacterial loads in lymph node tissues were also reduced

173 Joint bacterial loads in MyD88(-/-) mice were significantly gr

174 High airway bacterial loads in non-CF bronchiectasis are associated

175 ystem displayed significantly increased lung bacterial loads in response to M. bovis BCG infection.

176 ty (IBC) pathway, accompanied by diminishing bacterial loads in the bladder.

177 survival advantage, accompanied by decreased bacterial loads in the blood, lungs, liver, and spleen.

178 evere ataxia, which was associated with high bacterial loads in the CNS as well as clear histopatholo

179 occal keratitis, but has variable effects on bacterial loads in the cornea.

180 mutants achieved normal infection rates and bacterial loads in the flea midgut but produced a less c

181 Bacterial loads in the gastric tissues were also much hi

182 s of FyuA-specific serum IgG correlated with bacterial loads in the kidneys [Spearman's rank correlat

183 Interestingly, bacterial loads in the lungs are similar early after ino

184 sst1-dependent necrosis was observed at low bacterial loads in the lungs during reactivation of the

185 ation of CG combined with NE does not reduce bacterial loads in the lungs of M. tuberculosis-infected

186 increased mortality accompanied by enhanced bacterial loads in the lungs, blood, and distant organs

187 . typhi and develop comparable pathology and bacterial loads in the organs, demonstrating that the pl

188 emented group presented significantly higher bacterial loads in the peri-implant sulcus but significa

189 eudomonas aeruginosa substantially decreased bacterial loads in the wound and prevented the spread of

190 importantly, presented significantly reduced bacterial loads in their lungs and spleens following pat

191 cular fluid do not dramatically reduce total bacterial loads in this in vitro biofilm model, but caus

192 culture and in macrophages, and also reduced bacterial loads in vivo.

193 with a mastitis-causing E. coli strain, the bacterial load increased rapidly, triggering an intense

194 lly infected Smurf1(-/-) mice have increased bacterial load, increased lung inflammation, and acceler

195 riforme manifesting as a relapsing-remitting bacterial load, interspersed by periods when the organis

196 neumonia and otitis), and that high neonatal bacterial load is a key contributor to the development o

197 o associated vertical transmission, and that bacterial load is carried in the seed coat, crease tissu

198 Furthermore, bacterial load is increased in germ-line cells passing t

199 < .0001), together with decreased pulmonary bacterial loads, less severe histopathological scores, a

200 loma function based on three metrics - total bacterial load, macrophage activation levels, and apopto

201 In comparison to culture, the molecular bacterial load (MBL) assay is unaffected by other microo

202 We evaluated the use of the molecular bacterial load (MBL) assay, for measuring viable Mycobac

203 dly after rhinovirus infection and virus and bacterial loads measured with quantitative polymerase ch

204 For bacterial load measurements in the different types of sp

205 compare the ability of the assay to perform bacterial load measurements on sputum samples with versu

206 ation, AT-RvD1-treated mice had reduced NTHi bacterial load, mediated by enhanced clearance by macrop

207 fection treatment with RvD1 and RvD5 reduced bacterial loads, mitigated inflammation, and rescued the

208 ungs and an increased mortality rate without bacterial load modifications in the lungs, indicating th

209 Bacterial loads, MODS, leukopenia, neutrophil infiltrati

210 ture time-to-positivity (TTP; a surrogate of bacterial load), MTB/RIF TB-specific and internal positi

211 Lung injuries were assessed by bacterial load, myeloperoxidase activity, endothelial pe

212 sed enterocyte death resulted in the highest bacterial load observed starting from early adulthood.

213 Bacterial load of leaves increased significantly over ti

214 seased versus healthy animals, and the total bacterial load of newborn calves at day 3 was higher for

215 reduction of two orders of magnitude in the bacterial load of the rats was observed within a few hou

216 resulted in 3- to 4-log reductions in median bacterial loads of BVAB1 (P=0.02), BVAB2 (P=0.0004), BVA

217 Bacterial loads of Porphyromonas gingivalis, T. forsythi

218 riants on the course of infection and on the bacterial loads of the two variants in the genital tract

219 Sputum virus load peaked on Days 5-9 and bacterial load on Day 15.

220 vein catheter infection, dabigatran reduced bacterial load on jugular vein catheters, as well as met

221 ocesses may lead to the observed increase in bacterial load on the carcass surface in the presence of

222 No such difference in bacterial load or lesion size was detected in galectin-3

223 g S. aureus inoculation but had no effect on bacterial load or polymorphonuclear leukocyte (PMN) numb

224 However, this was independent of bacterial load or variation in PO, providing evidence fo

225 DeltaLF mutant exhibited no mortality, brain bacterial load, or evidence of meningitis compared to mi

226 y protein 2 did not affect clinical outcome, bacterial loads, or lung immunopathology.

227 The daily fall in bacterial load over 14 days was 0.176, 0.168, 0.167, 0.2

228 (>/= 12 wk) hyperglycemia features increased bacterial load, overproduction of several cytokines, and

229 ferences in clinical scores (P >/= 0.440) or bacterial loads (P = 0.736), however, 4/12 (33%) of the

230 Surprisingly, bacterial load plays a less important role than TNF in i

231 han did PBS controls and exhibited decreased bacterial load, PMN infiltrate, and corneal mRNA levels

232 mouse IL-33 (rmIL-33) and disease severity, bacterial load, polymorphonuclear neutrophils (PMN) infi

233 hyperalgesia in mice is correlated with live bacterial load rather than tissue swelling or immune act

234 ans, either opsonized or not, with different bacterial load ratios.

235 Bacterial loads recovered from infected corneas were hig

236 der more aggressive antimicrobials for rapid bacterial load reduction in high-risk SaB patients.

237 y without antibiotics on milk microbiome and bacterial load, respectively.

238 ty14 mice, the increased splenic and hepatic bacterial load resulted from an intrinsic defect in inna

239 Coinfection resulted in a bacterial load similar to monospecies infection but with

240 ion on nonerythroid cells (EPOR rescued) had bacterial loads similar to those of wild-type mice follo

241 FQ and compare efficacy by multiple metrics: bacterial load, sterilization rates, early bactericidal

242 tion in serum correlated strongly with mouse bacterial load, suggesting some role in immune regulatio

243 ed a relatively high proportion of the total bacterial load, suggesting that routine CF culture may u

244 provided greater reductions of PI, GI, total bacterial load, T. forsythia, A. actinomycetemcomitans,

245 d pendrin knockout (KO) mice had higher lung bacterial loads than infected pendrin-expressing mice bu

246 caused larger lesions and resulted in higher bacterial loads than protease-lacking bacteria.

247 1443, the psiPLY-immunized rabbits had lower bacterial loads than the control rabbits (P = 0.0008).

248 ation results in minimal mortality and lower bacterial loads than thorax inoculation.

249 recruitment early after infection, and lower bacterial loads, than wild-type (WT) mice.

250 , variation with depth and time of the total bacterial load, the abundance of faecal indicator bacter

251 As a test of bacterial load, the assay produced similar results when

252 nes in serum correlate with increased tissue bacterial loads throughout 4 weeks of infection.

253 cellular cAMP) reduced kidney infection (ie, bacterial load, tissue destruction); this was associated

254 ctivation of host nematode autophagy reduces bacterial loads to the same magnitude as antibiotic ther

255 Median bacterial load (TTP in days) was the strongest associate

256 llenge in Cmah(-/-) mice leads to heightened bacterial loads, virulence, and NanA expression.

257 The initial mean bacterial load was 2.15 log copies/mL, and the rate of b

258 The nasopharyngeal bacterial load was assessed in naive animals of both str

259 The decline in lung bacterial load was assessed monthly using charcoal-conta

260 The reduced bacterial load was associated with enhanced infiltration

261 Increasing bacterial load was associated with increasing disease se

262 ated salivary flow was measured and salivary bacterial load was calculated for total bacteria, Strept

263 anscription-PCR (qRT-PCR) confirmed that the bacterial load was decreased in these mutant flies compa

264 The bacterial load was estimated in sequential sputum sample

265 Bacterial load was greater at seven days postpartum than

266 The bacterial load was higher inside IH implants (P = 0.000)

267 Most notably, bacterial load was increased at 5 days postinfection by

268 The enhancement of bacterial load was mediated by human CD4(+) cells and as

269 vaccinated mice, a significant reduction in bacterial load was observed in intestinal tissues and th

270 ignificantly less pulmonary inflammation and bacterial load was observed in mif(P1G/P1G) compared wit

271 A significantly higher bacterial load was recovered from the vitreous of PLY pa

272 Unexpectedly, bacterial load was reduced.

273 Environmental bacterial load was repeatedly measured in surface and ae

274 Quantification of bacterial load was verified by quantitative PCR (qPCR) a

275 eaction assays were recently used to monitor bacterial loads; we hypothesized that the rate of bacter

276 y, pharmacokinetics of rifampin, and fall in bacterial load were assessed.

277 Viral titer and bacterial load were compared following infection of wild

278 egatibacter actinomycetemcomitans, and total bacterial load were determined by a real-time polymerase

279 mice were bacteremic, but no differences in bacterial load were identified between wild-type and Vil

280 Clinical disease activity and bacterial load were monitored.

281 The increases in mortality and bacterial load were reversed by a GABAA antagonist, bicu

282 s, T. forsythia, Parvimonas micra, and total bacterial load were significantly higher at peri-implant

283 Bacterial loads were also calculated for 8 bacterial pat

284 es (ITC), amino acids (AA), free sugars, and bacterial loads were analysed throughout the supply chai

285 Bacterial loads were assessed in the lungs and spleen.

286 red weekly, and mucosal immune responses and bacterial loads were assessed up to 2 months postinfecti

287 High bacterial loads were associated with higher serum interc

288 ta(-/-) mice early during infection, whereas bacterial loads were increased in C/EBPdelta(-/-) mice l

289 , a critical caveat to those results is that bacterial loads were not quantified.

290 alis and A. tumefaciens infection, increased bacterial loads were observed, indicating that hypercapn

291 oth WT and Gal3-deficient mice, although the bacterial loads were still higher in the latter.

292 c lung injury, it resulted in increased lung bacterial load when Akt2(-/-) mice were infected with Ps

293 owed accelerated mortality and greater organ bacterial load when challenged with Listeria monocytogen

294 host and for attaining a threshold level of bacterial load, which is a prerequisite for the onset of

295 Infection also increased the bacterial load while reducing the abundance of the Archa

296 suggested that a combination of intermediate bacterial loads with low levels TNFalpha administration

297 population and quantify the heterogeneity in bacterial load; with infected badgers shedding between 1

298 Bacterial loads within hearts were the same as in wild-t

299 teriuria (ASB), characterized by significant bacterial loads without lack symptoms.

300 the hypothesis that disease severity and/or bacterial loads would be significantly higher in a Type