ライフサイエンスコーパス: bacterial meningitis

1 BS) have further changed the epidemiology of bacterial meningitis.

2 ospinal fluid profile indistinguishable from bacterial meningitis.

3 reases neurologic sequelae in a rat model of bacterial meningitis.

4 ponses in CNS inflammatory diseases, such as bacterial meningitis.

5 ntravenous administration of ceftriaxone for bacterial meningitis.

6 th parenteral antibiotics, although few have bacterial meningitis.

7 understanding of the role of inflammation in bacterial meningitis.

8 rile convulsive status epilepticus had acute bacterial meningitis.

9 lammation in animal models and patients with bacterial meningitis.

10 meningitidis is the major causative agent of bacterial meningitis.

11 oniae (pneumococcus) is the primary cause of bacterial meningitis.

12 mproving outcome in subsets of patients with bacterial meningitis.

13 degrees C had a rate of 0.4% for bacteremia/bacterial meningitis.

14 herwise healthy and present early with acute bacterial meningitis.

15 We identified 26 children with bacterial meningitis.

16 idemiology during the past decade than acute bacterial meningitis.

17 h antimicrobial agents, in humans with acute bacterial meningitis.

18 st in developing novel strategies to prevent bacterial meningitis.

19 ory cascade leading to tissue destruction in bacterial meningitis.

20 Alzheimer's disease, multiple sclerosis and bacterial meningitis.

21 nsplants from 33 cadaveric donor livers with bacterial meningitis.

22 erity of neurological damage in experimental bacterial meningitis.

23 ain is a pivotal event in the progression of bacterial meningitis.

24 cids (EAA) from brain tissue of animals with bacterial meningitis.

25 ococcus pneumoniae, the most common cause of bacterial meningitis.

26 as of inflammation in multiple sclerosis and bacterial meningitis.

27 tment into the central nervous system during bacterial meningitis.

28 urologic sequelae, including deafness, after bacterial meningitis.

29 ating complement expression in this model of bacterial meningitis.

30 urella multocida is a rare cause of neonatal bacterial meningitis.

31 to contribute to intrathecal inflammation in bacterial meningitis.

32 In this study we explored the role of ROI in bacterial meningitis.

33 vide a therapeutic approach for treatment of bacterial meningitis.

34 hree pathogens responsible for most cases of bacterial meningitis.

35 is is the most frequent and critical type of bacterial meningitis.

36 treatment and contributes to brain damage in bacterial meningitis.

37 nimal role in the early host response during bacterial meningitis.

38 human pathogen causing pneumonia, sepsis and bacterial meningitis.

39 ocedure and had community-acquired anaerobic bacterial meningitis.

40 e, and S aureus as the causative pathogen of bacterial meningitis.

41 e observed in patients with septic shock and bacterial meningitis.

42 as identified in 24 of 1025 episodes (2%) of bacterial meningitis.

43 e identified as significant risk factors for bacterial meningitis.

44 those with fungal (13), arboviral (10), and bacterial meningitis (7).

45 cus pneumoniae (SPN) is the leading cause of bacterial meningitis, a disease with high attributable m

46 treptococcus pneumoniae is the main cause of bacterial meningitis, a life-threating disease with a hi

47 ee most common pathogens accounting for most bacterial meningitis, a serious global infectious diseas

48 Acute bacterial meningitis (ABM) in adults residing in resourc

49 High mortality burden from Acute Bacterial Meningitis (ABM) in resource-poor settings has

50 In suspected acute bacterial meningitis (ABM), cerebral computerized tomogr

51 icenter observational study of children with bacterial meningitis, adjuvant corticosteroid therapy wa

52 Brain injury due to bacterial meningitis affects multiple areas of the brain

53 95% confidence interval [CI], 3.1%-4.4%) had bacterial meningitis and 3174 (96.3%; 95% CI, 95.5%-96.9

54 CSF from 149 Malawian adults with bacterial meningitis and 39 controls were analyzed using

55 de key insight into the seasonal dynamics of bacterial meningitis and add to knowledge about the glob

56 criteria accurately differentiated TBM from bacterial meningitis and could be considered for use in

57 eurobehavioral performance was altered after bacterial meningitis and could be correlated with histol

58 ults and children with common types of acute bacterial meningitis and has been of proven value in the

59 s is the most common and aggressive cause of bacterial meningitis and induces a novel apoptosis-induc

60 Niamey, Niger, to determine risk factors for bacterial meningitis and invasive bacterial disease.

61 Neisseria meningitidis causes bacterial meningitis and is therefore responsible for co

62 reptococcus pneumoniae is the major cause of bacterial meningitis and it damages the hippocampus by i

63 not improve outcome in patients with severe bacterial meningitis and may even be harmful.

64 gender unexpectedly broad protection against bacterial meningitis and may provide a therapeutic targe

65 up B Streptococcus (GBS) is a major cause of bacterial meningitis and neurological morbidity in newbo

66 umoniae (pneumococcus) is a leading cause of bacterial meningitis and neurological sequelae in childr

67 een a dramatic reduction in the incidence of bacterial meningitis and of occult bacteremia since the

68 a diagnosis of malaria-slide-negative acute bacterial meningitis and other nonspecific encephalopath

69 eria meningitidis (Nm) is a leading cause of bacterial meningitis and sepsis globally.

70 Neisseria meningitidis is a major cause of bacterial meningitis and sepsis worldwide.

71 terial (for example, tuberculosis, syphilis, bacterial meningitis and sepsis), fungal (for example, c

72 ria meningitidis is a human pathogen causing bacterial meningitis and sepsis.

73 eria meningitidis (Nm) is a leading cause of bacterial meningitis and sepsis.

74 Neisseria meningitidis is a leading cause of bacterial meningitis and septicemia in children and youn

75 meningitidis is one of the leading causes of bacterial meningitis and septicemia in children.

76 negative pathogenic bacteria responsible for bacterial meningitis and septicemia, and the sexually tr

77 transmitted infection gonorrhea and serious bacterial meningitis and septicemia, respectively.

78 Neisseria meningitidis causes bacterial meningitis and septicemia.

79 en serious conditions, such as bacteremia or bacterial meningitis, and minor illnesses.

80 for the pathogenesis of brain edema in acute bacterial meningitis, and suggest that inhibition of AQP

81 the incidence and impact of endocarditis in bacterial meningitis are unknown.

82 Significant injury during bacterial meningitis arises from mechanisms of neuronal

83 a has been implicated in the pathogenesis of bacterial meningitis as a potent mediator of inflammatio

84 We defined bacterial meningitis as the presence of H. influenzae, S

85 r 31, 2006, of 2780 children discharged with bacterial meningitis as their primary diagnosis from 27

86 old: to document the current epidemiology of bacterial meningitis at a tertiary care medical center a

87 -8 levels were observed within patients with bacterial meningitis at fever onset, which was not evide

88 Sahel region of West Africa has the highest bacterial meningitis attack and case fatality rate in th

89 important causes of community and nosocomial bacterial meningitis based on International Classificati

90 ditis is an uncommon coexisting condition in bacterial meningitis but is associated with a high rate

91 Endocarditis may precede or complicate bacterial meningitis, but the incidence and impact of en

92 iability may contribute to susceptibility of bacterial meningitis, but which genes contribute to the

93 14 patients categorized as very low risk for bacterial meningitis by the Bacterial Meningitis Score,

94 n was evaluated in culture-confirmed TBM and bacterial meningitis cases.

95 of bacteria accounted for 60% (3790/6286) of bacterial meningitis cases: Neisseria meningitidis (1350

96 Invasive bacterial meningitis caused by Neisseria meningitidis ca

97 Community-acquired bacterial meningitis causes substantial morbidity and mo

98 ia meningitidis is one of the main agents of bacterial meningitis, causing substantial morbidity and

99 , or stool samples, including bacteremia and bacterial meningitis classified as IBIs.

100 Bacterial meningitis continues to be a substantial cause

101 The rate of bacterial meningitis declined by 55% in the United State

102 in-8 in a temporal manner may indicate early bacterial meningitis development in neurosurgical patien

103 , a group of children with culture-confirmed bacterial meningitis, diagnosed between 2003 and 2009, w

104 Mortality from adult bacterial meningitis exceeds 50% in sub-Saharan Africa.

105 Half of the survivors of bacterial meningitis experience motor deficits, seizures

106 We describe the epidemiologic features of bacterial meningitis five years after the H. influenzae

107 to the Netherlands Reference Laboratory for Bacterial Meningitis from 1989 through 1997, were assess

108 trials undertaken in Blantyre investigating bacterial meningitis from 1990 to the current time and c

109 linic and laboratory features to distinguish bacterial meningitis from other diseases can be useful.

110 We developed the first bacterial meningitis global database by compiling monthl

111 exist that can protect against some types of bacterial meningitis (Haemophilus influenzae type b, Nei

112 s, but its ability to differentiate TBM from bacterial meningitis has not been evaluated.

113 A substantial reduction in bacterial meningitis has occurred in the UK following su

114 Neisseria meningitidis, a causative agent of bacterial meningitis, has a relatively small repertoire

115 Rates of bacterial meningitis have declined in children, but not

116 The rates of bacterial meningitis have decreased since 1998, but the

117 gnificantly reduce mortality associated with bacterial meningitis; however, in children, studies reve

118 idis serogroup B (MnB) is a leading cause of bacterial meningitis; however, MnB is most commonly asso

119 that classifies patients at very low risk of bacterial meningitis if they lack all of the following c

120 n 1.8% of infants (2.4% of those tested) and bacterial meningitis in 0.5%.

121 Estimated incidence of bacterial meningitis in 2012 was 20 per 100,000 cases in

122 Adjuvant therapy with dexamethasone for bacterial meningitis in adults from an area with a high

123 a, where it emerged as an important cause of bacterial meningitis in adults.

124 us suis has emerged as an important cause of bacterial meningitis in adults.

125 Mortality from bacterial meningitis in African adults is significantly

126 study analysing data from clinical trials of bacterial meningitis in Blantyre, Malawi to investigate

127 ys) in adults with an admission diagnosis of bacterial meningitis in Blantyre, Malawi.

128 During reinforced surveillance of acute bacterial meningitis in Burkina Faso, meningococcal stra

129 Bacterial meningitis in childhood is almost exclusively

130 In a Danish population, bacterial meningitis in childhood was associated with lo

131 ctioning in adult life among persons who had bacterial meningitis in childhood.

132 disease is no longer a major cause of acute bacterial meningitis in children but, instead, cases are

133 r the past several decades, the incidence of bacterial meningitis in children has decreased but there

134 neumoniae is the most common cause of severe bacterial meningitis in children, the elderly, and immun

135 a meningitidis is a major causative agent of bacterial meningitis in human beings, especially among y

136 mine the incidence, etiology, and outcome of bacterial meningitis in infants aged <90 days in the Uni

137 nce of dangerous infectious diseases such as bacterial meningitis in infants and adults.

138 Adults with community acquired bacterial meningitis in Malawi present with a severe cli

139 oli K1 is the leading cause of gram-negative bacterial meningitis in neonates.

140 Streptococcus (GBS) is the leading cause of bacterial meningitis in newborn infants.

141 and Drug Administration received reports of bacterial meningitis in patients with cochlear implants

142 oups A and X are among the leading causes of bacterial meningitis in the African meningitis belt.

143 hort study of adults with community-acquired bacterial meningitis in the Netherlands from 2006 to 201

144 seria meningitidis has been a major cause of bacterial meningitis in the sub-Saharan region of Africa

145 On the basis of 248 cases of bacterial meningitis in the surveillance areas, the rate

146 e in meningitis due to H. influenzae type b, bacterial meningitis in the United States is now a disea

147 lus influenzae type b was the major cause of bacterial meningitis in the United States, and meningiti

148 nues to be the leading identifiable cause of bacterial meningitis in the USA, but with a significant

149 The incidence of bacterial meningitis in young infants remains unchanged

150 multiple infectious complications, including bacterial meningitis, in adults.

151 The median age of persons with bacterial meningitis increased greatly, from 15 months i

152 Bacterial meningitis is a condition in which inflammatio

153 Bacterial meningitis is a disease worsened by neutrophil

154 Liver transplantation from donors with bacterial meningitis is a safe procedure provided both d

155 Bacterial meningitis is a serious health concern worldwi

156 Bacterial meningitis is a serious infection of the CNS t

157 Bacterial meningitis is an infection of the thin membran

158 In sub-Saharan Africa, bacterial meningitis is common and is associated with a

159 tion of antibiotic treatment on suspicion of bacterial meningitis is important, but it is not enough

160 Acute bacterial meningitis is more common in resource-poor tha

161 Although the pathogenesis of bacterial meningitis is not completely understood, knowl

162 ningitis among young children, the burden of bacterial meningitis is now borne more by older adults.

163 high mortality and morbidity associated with bacterial meningitis is the incomplete understanding of

164 The risk of bacterial meningitis is very low (0.1%) in patients with

165 Acute bacterial meningitis is widely considered to result from

166 atients, and for patients with endocarditis, bacterial meningitis, lymphoma/leukemia, HIV/AIDS, inter

167 The use of cadaveric donors with bacterial meningitis may be associated with an increased

168 C5a was detected in all patients with bacterial meningitis (n = 9), in 6 of 18 patients with a

169 E. coli O18:K1:H7 as the archetypal neonatal bacterial meningitis (NBM) isolate RS218.

170 hia coli isolates from infants with neonatal bacterial meningitis (NBM), as submitted to the Netherla

171 control patients, and infants with neonatal bacterial meningitis (NBM), were analyzed and were compa

172 An estimated 4100 cases and 500 deaths from bacterial meningitis occurred annually in the United Sta

173 Bacterial meningitis occurs when bloodborne pathogens in

174 occus pneumoniae is the most common cause of bacterial meningitis of high mortality and morbidity.

175 We identified 3188 patients with bacterial meningitis; of 3155 patients for whom outcome

176 to comprehensively assess seasonal trends in bacterial meningitis on a global scale.

177 nly significantly increased in patients with bacterial meningitis on the fourth day post fever.

178 on UK charity, whose child had suffered from bacterial meningitis or meningococcal septicaemia within

179 arditis (OR = 8.3; CI, 4.9-13.9; P < .0001), bacterial meningitis (OR = 3.8; CI, 1.2-12.0; P = .023),

180 and, potentially, with an increased risk of bacterial meningitis (OR=1.30; P=0.0024).

181 Long-term surveillance of bacterial meningitis outside of the epidemic "meningitis

182 d morbidity remain high in adults with acute bacterial meningitis, particularly when due to Streptoco

183 a range of processes known to be involved in bacterial meningitis pathogenesis was examined.

184 EBV was detected in 79 of 149 bacterial meningitis patients.

185 type b (Hib) is a leading cause of childhood bacterial meningitis, pneumonia, and other serious infec

186 Neonatal bacterial meningitis remains a disease with unacceptable

187 Bacterial meningitis remains a major cause of morbidity

188 We analyzed data on cases of bacterial meningitis reported among residents in eight s

189 rosis, cerebral ischemia and hemorrhage, and bacterial meningitis respond to treatment with MMPIs.

190 Brain injury due to bacterial meningitis results in a high mortality rate an

191 To validate the Bacterial Meningitis Score in the era of widespread pneu

192 The Bacterial Meningitis Score may be helpful to guide clini

193 This large multicenter study validates the Bacterial Meningitis Score prediction rule in the era of

194 ery low risk for bacterial meningitis by the Bacterial Meningitis Score, only 2 had bacterial meningi

195 ly developed a clinical prediction rule, the Bacterial Meningitis Score, that classifies patients at

196 itivity and negative predictive value of the Bacterial Meningitis Score.

197 sease activity had a latitudinal trend, with bacterial meningitis seasons peaking during the winter m

198 y the Bacterial Meningitis Score, only 2 had bacterial meningitis (sensitivity, 98.3%; 95% CI, 94.2%-

199 isseria are obligate human pathogens causing bacterial meningitis, septicaemia and gonorrhoea.

200 ion, single-dose surgical prophylaxis, acute bacterial meningitis, spontaneous bacterial peritonitis,

201 o the major Gram-positive causative agent of bacterial meningitis, Streptococcus pneumoniae, and show

202 ared with children admitted to hospital with bacterial meningitis symptoms but negative diagnosis.

203 f the inflammatory responses associated with bacterial meningitis that emphasize the need for early d

204 We conclude that in the treatment of severe bacterial meningitis, the application of moderate hypoth

205 e diagnosis of enteroviral meningitis versus bacterial meningitis, thereby resulting in timely and ap

206 In persons with community-acquired bacterial meningitis, three baseline clinical features o

207 omide could have a therapeutic role in acute bacterial meningitis through inhibition of IL-8-mediated

208 We documented bacterial meningitis trends among adults and children pr

209 ections (IBIs), defined as bacteremia and/or bacterial meningitis, using complete blood cell count pa

210 d Wales, the incidence of confirmed neonatal bacterial meningitis was 0.21 (n = 167; 95% CI, .18-.25)

211 Postimplantation bacterial meningitis was strongly associated with the us

212 lay an important role in the pathogenesis of bacterial meningitis, we examined whether functional pol

213 m these data, we estimate that 5755 cases of bacterial meningitis were caused by these five pathogens

214 Seven hundred and fifteen episodes of bacterial meningitis were evaluated.

215 Adults with community acquired bacterial meningitis were included if the CSF culture is

216 </=8 for <12 hours) with community-acquired bacterial meningitis were randomized.

217 ys prior to fever onset within patients with bacterial meningitis when compared with both aseptic and

218 Bacterial meningitis, which is caused mainly by Neisseri

219 ave dramatically altered the epidemiology of bacterial meningitis, while the methodology for culturin

220 hey treated 61 of the 63 cases of bacteremia/bacterial meningitis with antibiotics.

221 free diagnosis of these three major types of bacterial meningitis, with high sensitivity and specific

222 or the differential diagnosis of aseptic and bacterial meningitis within neurosurgical patients.

223 Neisseria meningitidis is a major cause of bacterial meningitis worldwide, especially in the Africa

224 of Neisseria meningitidis, a major cause of bacterial meningitis worldwide.

225 lts, strep throat, scarlet fever, pneumonia, bacterial meningitis, yeast infections, urinary tract in