ライフサイエンスコーパス: balance of

1 d NTRC redox systems are linked by the redox balance of 2-Cys Prxs, which is crucial for chloroplast

2 t of the 7s-orbital and how this affects the balance of 5f- versus 6d-orbital bonding character.

3 he biomass weight and ensuring complete mass balance of a model.

4 protein phosphorylation is determined by the balance of actions by kinases and phosphatases, and the

5 ontrol that dynamically adjusts the relative balance of activity between the two eyes [13, 14].

6 he motivation to eat depends on the relative balance of activity in distinct brain regions that induc

7 support the idea that there is a coordinated balance of activity upstream of the corticospinal output

8 eries identified analogues with an excellent balance of ADME properties and potency; however, potenti

9 ux therefore develops via alterations in the balance of aggressive and defensive forces.

10 Mice lacking MIWI2 exhibited an altered balance of airway epithelial cells, demonstrating fewer

11 inst these side reactions requires a careful balance of all these factors.

12 we found that FH levels determine a delicate balance of alternative pathway activity, thus affecting

13 Mass balance of As chemical fractionation showed that ~89-100

14 nd lipid homeostasis pathways that alter the balance of atherosclerotic plaque progression and regres

15 in infants; however, achieving an effective balance of attenuation and immunogenicity has proven cha

16 of the supramolecular assembly by tuning the balance of attractive and repulsive intermolecular force

17 strong axodendritic synaptic depression, the balance of axodendritic and dendrodendritic circuitry in

18 CC development depends on the proper balance of axon growth cone attractive and repellent cue

19 1 model of dystonia can upset the functional balance of basal ganglia circuits, affecting direct and

20 This work demonstrates that the balance of base pi-stacking interactions between the end

21 inhibited prosurvival pathways, shifted the balance of Bcl-2 family proteins in favor of apoptosis,

22 erage risk of local relapse will improve the balance of beneficial versus adverse effects compared wi

23 omes beyond hematologic outcomes, and 4) the balance of benefit and harm of iron supplementation of i

24 ancer risk, and comorbidity level affect the balance of benefit and harms of screening mammography; a

25 years provided similar LYG and a comparable balance of benefit and screening burden.

26 Therefore, the USPSTF concludes that the balance of benefits and harms cannot be determined.

27 g for adults aged 60 years or older, but the balance of benefits and harms is unclear in light of new

28 rrent evidence is insufficient to assess the balance of benefits and harms of adjunctive screening fo

29 rrent evidence is insufficient to assess the balance of benefits and harms of initiating aspirin use

30 rrent evidence is insufficient to assess the balance of benefits and harms of initiating aspirin use

31 rrent evidence is insufficient to assess the balance of benefits and harms of initiating statin use i

32 rrent evidence is insufficient to assess the balance of benefits and harms of performing screening pe

33 rrent evidence is insufficient to assess the balance of benefits and harms of screening for celiac di

34 rrent evidence is insufficient to assess the balance of benefits and harms of screening for impaired

35 rrent evidence is insufficient to assess the balance of benefits and harms of screening for lipid dis

36 rrent evidence is insufficient to assess the balance of benefits and harms of screening for MDD in ch

37 rrent evidence is insufficient to assess the balance of benefits and harms of screening for OSA in as

38 rrent evidence is insufficient to assess the balance of benefits and harms of screening mammography i

39 rrent evidence is insufficient to assess the balance of benefits and harms of vision screening in chi

40 rrent evidence is insufficient to assess the balance of benefits and harms of visual skin examination

41 screening will maintain a similar or better balance of benefits and harms than average-risk women re

42 ould not be expected to alter materially the balance of benefits and harms.

43 ulation model to systematically estimate the balance of benefits and harms.

44 status is needed to inform approaches to the balancing of benefits and harms of screening and routine

45 dulations in the increase/decrease discharge balance of BG downstream neurons during temporal discoun

46 Accordingly, depletion of ZIC2 shifted the balance of bivalent histone modifications toward more ac

47 hes osteoclast bone resorption, shifting the balance of bone homeostasis and favoring bone acquisitio

48 and bone formation, and restoring the normal balance of bone remodeling is highly desirable for ident

49 s in observational studies, none replace the balance of both known and unknown prognostic factors off

50 e determined by performing steady-state flux balances of both the gas and liquid flowing into the rea

51 ole in regulating the epithelial-mesenchymal balance of breast cancer cells and that WT1-expressing t

52 racellular cAMP levels are determined by the balance of cAMP synthesis by adenylyl cyclases and degra

53 is clear that they play a vital role in the balance of carbon fixation and water loss.

54 During human heart failure, the balance of cardiac energy use switches from predominantl

55 ly incorporated into models that examine the balance of cargo fluxes in cells and into models of the

56 Systemic redox balance of cataract patients was significantly altered i

57 of the cellular component-specifically, the balance of CD68(+), iNOS(+) M1- and CD68(+), CD163(+) M2

58 oint to the control of contact guidance by a balance of cell-substratum and cell-cell interactions, m

59 rmoxic cells remotely regulate the acid-base balance of cells at the hypoxic core of connexin-coupled

60 e challenged these processes by changing the balance of cellular dNTPs.

61 The resulting balance of cellular material and airspace is expected to

62 Spatiotemporal balancing of cellular proliferation and differentiation

63 historical statistical data to analyze the C balance of Chinese croplands during the 1980s and 1990s,

64 The careful selection and balance of cocatalysts have led to enhanced reactivity,

65 regarding how HIV infection might change the balance of commensal bacteria in the gut.

66 stem, the dipolar trident lattice, where the balance of competing interactions between nearest-neighb

67 y mechanisms that are thought to tip a local balance of competing physical forces; cell-to-cell and c

68 with persistent inattention lost the typical balance of connections within the default mode network (

69 tion in populations near equilibrium under a balance of constant viability selection and variation pr

70 re research into mechanisms that restore the balance of control between signals of homeostasis and mo

71 Balance of cortical excitation and inhibition (EI) is th

72 nic solar cell optimization requires careful balancing of current-voltage output of the materials sys

73 the striatum, oxytocin is poised to bias the balance of DA tone through multiple sites in vertebrate

74 responses to noxious inputs manifest from a balance of descending facilitation and inhibition.

75 l's confidence in the estimated effects, the balance of desirable (i.e., benefits) and undesirable (i

76 its confidence in the estimated effects, the balance of desirable (i.e., benefits) and undesirable (i

77 values the main outcomes, the magnitude and balance of desirable and undesirable outcomes, the resou

78 ulated recommendations after considering the balance of desirable consequences (benefits) versus unde

79 in excellent agreement, providing 100% mass balance of detected analyte.

80 Lesion severity is affected by the balance of different CD4 T cell subsets, with greater se

81 istent with our data, that indicated how the balance of different compounds affects these traits indi

82 A delicate balance of different types of intramolecular interaction

83 ced repetition-rate stability occurs through balance of dispersive-wave recoil and Raman-induced soli

84 This balance of dissolution-precipitation shifts significantl

85 volve through genetic changes that alter the balance of dNTP binding and dissociation from DNA polyme

86 g link between dN frequencies in RNA and the balance of dNTPs and ribonucleoside 5'-triphosphates (rN

87 he use of double mutant cycles, of molecular balances, of dynamic combinatorial libraries, and of cry

88 n CD4(+) T cells plays a crucial role in the balance of effector lineages, favoring the inflammatory

89 nitude of cell expansion and the appropriate balance of effector/memory CD8(+) T cell generation.

90 At present, based on an overall balance of efficacy and side effects, the patient is in

91 inical trials are strongly influenced by the balance of EGFR and PDGFRA activation in individual cell

92 ncing CSN or desmosome components shifts the balance of EGFR modifications from ubiquitination to ned

93 The balance of electron and hole states is found only when c

94 contrasting behavior reflects the different balance of electrostatic and conjugative interactions in

95 This outcome leads to a shift in the balance of endogenous bone marrow stroma, towards a comp

96 rt function is critically dependent upon the balance of energy production and utilization.

97 une signals dominate, and suggest a delicate balance of enhancing and suppressive signals.

98 ver, higher temperatures maintain better the balance of esters (acetate versus non-acetate) and pheno

99 To date, the balance of evidence indicates that the (G4C2)n repeat ca

100 The current balance of evidence suggests that CMVIG prophylaxis redu

101 rther empirical work is needed to assess the balance of evolutionary forces responsible for quantitat

102 for gluconeogenesis, indicating an intricate balance of exacerbated opposite metabolic processes in g

103 ion of advanced leads possessing a desirable balance of excellent in vitro GlyT-1 potency and selecti

104 actory bulb (AOB) experiences changes in the balance of excitation and inhibition at reciprocal synap

105 t studies reveal the importance of a precise balance of excitation and inhibition in neural circuits,

106 Balance of excitation and inhibition is a fundamental fe

107 considers ways in which disturbances in the balance of excitation and inhibition might develop and b

108 This radial motion opponency generates a balance of excitation and inhibition that makes LPLC2 no

109 The balance of excitation and inhibition, from cellular proc

110 hibitory neurotransmission, which alters the balance of excitation and inhibition.

111 t self-generate irregular activity through a balance of excitation and inhibition.

112 This altered balance of excitation and suppression reflects mechanism

113 not see any other significant alterations in balance of excitation/inhibition in any of the other aud

114 sual function that is thought to rely on the balance of excitation/inhibition in visual cortex [12-15

115 n-dependent phosphatase, enables homeostatic balancing of excitation and inhibition.

116 CANCE STATEMENT We present evidence that the balance of excitatory and disinhibitory inputs to a type

117 Establishment of a proper balance of excitatory and inhibitory connectivity is ach

118 nomous molecular mechanisms that control the balance of excitatory and inhibitory synapse function re

119 gest that loss of mTOR in the VTA shifts the balance of excitatory and inhibitory synaptic transmissi

120 vel link between working memory load and the balance of excitatory/inhibitory activity in the motor c

121 e show that the thermodynamic fission-fusion balance of excitons and electron-hole plasma can be effi

122 cal-trapping antioxidants (RTAs) relies on a balance of fast H-atom transfer kinetics and stability t

123 s feedback and the mechanisms regulating the balance of feedback excitation and inhibition remain unk

124 rowth cone, but rather because it alters the balance of forces that power the bulk forward translocat

125 Bipolar spindle assembly requires a balance of forces where kinesin-5 produces outward pushi

126 show that as long as packed cells present a balance of forces within tissue, they will be under a ph

127 In this work, based on the balance of forces, we derive conditions for a drop to se

128 ition plays a significant role in the carbon balance of forests in industrialized regions.

129 fects of a warmer and drier climate on the C balance of forests in this region will be felt for decad

130 These data suggest that the balance of free and mTORC1-associated Raptor governs hep

131 other eye, but in monkeys with amblyopia the balance of gain modulation is altered so that the weaker

132 le cell dysmaturation, restored a functional balance of gamma-band network oscillations, and allowed

133 minimizes interference with the natural mass balance of gases in environmental systems, and allows th

134 tem cell differentiation involves a delicate balance of gene expression and transposon repression.

135 some number impair fitness by disrupting the balance of gene expression.

136 ibitor development is regulated by a complex balance of genetic factors, such as FVIII genotype, and

137 Thus, the balance of GMP and MDP differentiation shapes the myeloi

138 er; however, the identification and activity-balance of GR compounds remained elusive.

139 The even balance of groups 1 and 2 in the human population points

140 egulatory feedback mechanism to optimize the balance of growth and stress responses.

141 ration and differentiation, and restores the balance of growth factors, creating a permissive environ

142 ng clinicians and their patients predict the balance of harms and benefits associated with SACT.

143 e Zone (ITCZ) is sensitive to changes in the balance of heat between the hemispheres which has fundam

144 of sinusoidal vessels and altered population balance of hematopoietic stem cells in the bone marrow,

145 l was developed from a model that achieved a balance of high performance (AUROCs, 0.945 and 0.932 in

146 0.05) in the hippocampus and a shift of the balance of hippocampal neurotransmitter receptor densiti

147 tion, these data support the notion that the balance of histone acetylation at the Nr4a promoters is

148 s suggest that PepT1 contributes to maintain balance of homeostasis and proper functions in the small

149 oxoplasma and host, leading to the intricate balance of host defence versus parasite survival.

150 its control over cellular functions, and the balance of hyaluronan synthesis and degradation determin

151 Volcanic eruptions can impact the mass balance of ice sheets through changes in climate and the

152 cell surfaces for the restoration of altered balance of immune control during T1D.

153 and reveal how it controls the evolutionary balance of immune recognition during host-pathogen inter

154 , loss of SOCS1 in CD11c(+) cells skewed the balance of immune response to infection by increasing in

155 However, its specific functions in the balance of immunity in vivo have been explored incomplet

156 s is crucial for controlling the appropriate balance of inflammation.

157 blockade by losartan may differently control balance of inflammatory cytokines, such as IL-6 and IL-8

158 sculpts neural mechanisms that regulate the balance of influence exerted by the two eyes on cortical

159 ross the estrous cycle due to a shift in the balance of inhibition and excitation across two BLA regi

160 y of the bronchial epithelium to control the balance of inhibitory and activating signals is essentia

161 Furthermore, the balance of inhibitory and excitatory boutons in the spin

162 ages are essential in maintaining a delicate balance of initiating immunity without causing collatera

163 gnaling during viral infection regulates the balance of innate lymphoid cells (ILC), a diverse class

164 integration in visual cortex by altering the balance of inputs that generate neuronal receptive field

165 The results here demonstrated that the balance of intermolecular interaction between TC-TC, TC-

166 behaviour of intertidal fauna such that the balance of interspecific interactions involved in commun

167 nfluences both the overall stability and the balance of intrinsic repeat stability and interfacial co

168 These observations argue that the balance of junctional and nuclear beta-catenin activity

169 re and water availability control the carbon balance of land ecosystems across spatial and temporal s

170 For instance, the energetic balances of larger animals are generally more sensitive

171 By modeling the balance of leaf energy inputs and outputs, we show that

172 We suggest that the balancing of linear and branched actin networks by Abl i

173 In three WWTPs, the total mass balance of LMG-N2-G ranged from 71 to 102%.

174 Planktonic communities are shaped through a balance of local evolutionary adaptation and ecological

175 increased stem cell polarity and a restored balance of lymphoid and myeloid cells in peripheral bloo

176 erular heparanase, and a marked shift in the balance of M1 and M2 glomerular macrophages.

177 Their structures result from the balance of many weak interactions, rather than from the

178 must alter and repurpose the normal cellular balance of membrane and protein flux, a process that is

179 nimizer hashing technique, allowing for good balance of memory usage throughout its execution.

180 ting possible involvement in maintaining the balance of metabolic phenotypes.

181 The balance of methylation levels at histone H3 lysine 4 (H3

182 repression of gene expression, and a precise balance of methyltransferases and demethylases within ce

183 out the mechanisms underlying the organismal balance of Mg(2+).

184 ng the microtubule, which suggests a precise balance of microtubule binding forces is required.

185 These results highlight the delicate balance of Mn(II) uptake and efflux systems controlled b

186 A delicate balance of molecular properties achieved via disciplined

187 E1 inhibition of MCAK activity regulates the balance of MT stability that determines the fidelity of

188 itization is required for quiescence/cycling balance of murine short-term hematopoietic stem cells an

189 The balance of myeloid populations and lymphoid populations

190 f FAs in cognitive function, and the optimal balance of n-6 and n-3 FAs depends on the cognitive func

191 ic and environmental factors, reflecting the balance of nature and nurture.

192 w that these collective results are due to a balance of network elasticity and force-induced cross-li

193 This dynamics is determined by the balance of nucleocytoplasmic shuttling, formin- and redo

194 In particular, D2R blockade shifted the balance of OFC connectivity from associative areas in th

195 Bone homeostasis depends on the functional balance of osteoblasts (OBs) and osteoclasts (OCs).

196 These results show that controlling the balance of oxazoline formation and glycosylation is key

197 optosis, that local glucose levels alter the balance of PCD pathways, and that clinically relevant ou

198 tation of the E3 ligase gene beta-Trcp2, the balance of PERIOD degradation is perturbed and the clock

199 anslation by modulating mRNA decay through a balance of PKA and Hog1 signalling.

200 on trophic strategy, but what determines the balance of plant and animal tissue omnivores consume is

201 tiates cell-fate decisions by modulating the balance of pluripotency and differentiation.

202 ficantly affect the movements and the energy balance of polar bears (Ursus maritimus) which forage, n

203 c alleles of Ras was highly dependent on the balance of positive (GAP) and negative (GEF) regulators

204 ation in the degree of rectification and the balance of positive versus negative changes in activity.

205 The close balance of precipitation and dissolution near equilibriu

206 interaction concerns to deliver the desired balance of preclinical in vitro properties.

207 d that KYNA biases the excitatory-inhibitory balance of prefrontal synaptic activity toward a state o

208 GL-dSACs are thus capable of shifting the balance of principal tufted versus mitral cell activity

209 plement and prions likely involves a complex balance of prion sequestration and destruction via local

210 omeostasis is maintained through an adequate balance of pro- and anti-inflammatory macrophages, we as

211 xternal superoxide levels, which reflect the balance of production and degradation processes.

212 in autoimmunity by changing the homeostatic balance of proinflammatory cytokines and the human immun

213 Peripheral pain signaling reflects a balance of pronociceptive and antinociceptive influences

214 Having the best balance of properties, 50 was selected for further evalu

215 ases myogenesis but also regulates the tight balance of protein synthesis and degradation.

216 hus, RADX is essential to achieve the proper balance of RAD51 activity to maintain genome stability.

217 flammation are all heavily influenced by the balance of rates of reaction and mass transport phenomen

218 Our work highlights the delicate balance of reaction conditions to control the synthesis

219 ellularly assessed as a means to disrupt the balance of reactive oxygen species (ROS) often elevated

220 A balance of reactivity and stability was struck by pruden

221 ntensive, requiring manual part assembly and balancing of regulator expression.

222 GATA3, and RIPK4) reflecting changes in the balance of regulatory/proallergic responses in periphera

223 ggests that hematopoietic stress changes the balance of renewal and differentiation in these homeosta

224 f new medical technologies involve a complex balance of research participant benefits versus risks an

225 mokine receptor CCR10 resulted in an altered balance of resident Tregs and CD4(+) effector T cells in

226 ibly reflecting uncertainty and the relative balance of rewards and losses.

227 ween 1998 and 2003, recipient HCV infection, balance of risk score >18, and pre-LT renal replacement

228 individual, with the goal of optimizing the balance of risks and benefits according to the values an

229 ccess, on the basis of each patient's unique balance of risks and benefits.

230 nt will remain vital to ensuring appropriate balance of risks and optimizing health outcomes.

231 nded model sum scores to determine where the balance of risks lay with the intervention.

232 the ROS defense capacity and maintained the balance of ROS generation and elimination under resting

233 of the epidermal barrier in AD can alter the balance of S. aureus entry into the dermis and provide a

234 prediction of CIN3+ showed that the optimal balance of sensitivity and specificity (75.7% and 77.5%,

235 ithin IDRs have evolved to ensure an optimal balance of sequence-encoded conformational properties, i

236 If the balance of signals favors activation, FcgammaRI nanoclus

237 fundamental properties such as the essential balance of singlet oscillator strength and triplet harve

238 tween dominant clades would have shifted the balance of soil-atmosphere water fluxes, and thus surfac

239 The delicate balance of steric and electronic parameters of the emplo

240 A healthy immune system results from a balance of stimulatory and inhibitory pathways that allo

241 whole embryo surface according to the global balance of stresses and the material behaviour of the ep

242 fur bacteria have failed to demonstrate mass balance of sulfur, indicating that unidentified oxidized

243 dopamine triggers a maladaptive shift in the balance of synaptic excitation and inhibition in the STN

244 ection deficits (GDDs) showed a shift in the balance of synaptic excitation and inhibition that was p

245 d found that perturbations in the endogenous balance of tau isoforms were sufficient to impair the tr

246 By altering the balance of tensions and pressures within the packed tiss

247 In addition, mass balances of terbutryn and octylisothiazolinone were dete

248 in regulating the excitatory and inhibitory balance of the adult brain.

249 ice can have strong effects on the radiative balance of the Arctic.

250 The USPSTF assessed the balance of the benefits and harms of folic acid suppleme

251 ver, the direct impact of dust on the energy balance of the Earth system remains poorly quantified, m

252 e cell stiffness, and that it depends on the balance of the ECM-triggered signalling pathways PI(3)K-

253 ility and to conditions that alter the redox balance of the electron transfer chain.

254 gardless of tissue location, the homeostatic balance of the epithelial barrier is skewed toward loss

255 ric circulation controls the mass and energy balance of the Greenland ice sheet through its impact on

256 The balance of the hydrogenation kinetics between adsorbed f

257 We explain the balance of the long-range attraction and repulsion force

258 sed whether dysregulation of the homeostatic balance of the major inhibitory and excitatory amino aci

259 n the rings contributes to the thermodynamic balance of the metal ligand cooperative reactions, chang

260 re" that maintains the excitatory/inhibitory balance of the nervous system.

261 a consequence of a deleterious shift in the balance of the normally stable resident oral microbiome.

262 enced lake trout foraging tactics (i.e., the balance of the number and duration of forays) but not th

263 dly so [6]-and may mark a stage at which the balance of the oral fissure shifted from mostly teeth to

264 well-calibrated tension defined by enthalpic balance of the phases.

265 mains controversial because of the uncertain balance of the potential benefits and risks when combine

266 he boundary counters the retraction, and the balance of the protrusion and retraction shapes the lame

267 ices should be adopted to improve the poor C balance of the remaining 22.4% of cropland to promote C

268 we examined the consequences of shifting the balance of the repressive histone H3 lysine 27 trimethyl

269 A careful examination of the energy balance of the system surprisingly revealed that the rol

270 ance, which is mostly determined by the root balance of the tree.

271 Cirrus clouds determine the radiative balance of the upper troposphere and the transport of wa

272 ines both strives toward a comprehensive net-balancing of the bias-variance trade-off.

273 inform approaches to improve the amount and balance of these essential nutrients in crops.

274 The relative balance of these factors will be context dependent and s

275 0 productions are associated with death, the balance of these inflammatory mediators does not seem to

276 une response is mounted in the new host, the balance of these opposing factors can significantly infl

277 Normal brain function relies on the careful balance of these opposing neural connections, and unders

278 The balance of these pathways is critical in maintaining a n

279 drives B-ALL and suggest that restoring the balance of these pathways might inhibit B-ALL.

280 erstanding how drier climates may offset the balance of these trade-offs as soils transition toward m

281 Particularly for softer metals, the optimal balance of these two effects occurs near reaction condit

282 pendently associated with mortality, but the balance of this response as modelled by an interleukin-6

283 These results support the concept that the balance of TIMP3 and ADAM17 activity modulates CBF throu

284 ing force fields fail to capture the correct balance of TMAO and urea interactions in ternary solutio

285 The 15/50 formulation displayed the best balance of tolerability and immunogenicity.

286 screte, elastic rods provide evidence that a balance of torque, tension, and elasticity stabilizes ne

287 l flexibility is grounded in the appropriate balancing of trade-offs between fast and slow movements

288 hat accelerated closure, each arising from a balance of transport and the prevailing ion gradients ac

289 ion regimes, and those regimes constrain the balance of tree size and the nature of branching events.

290 ed release system is capable of shifting the balance of Treg/T effectors and, in turn, preventing key

291 The carbon balance of tropical ecosystems remains uncertain, with t

292 s suggest that creativity involves an expert balance of two brain networks typically viewed as being

293 , changes in the activation enthalpy-entropy balance of up to 10 kcal/mol are almost perfectly balanc

294 oad range of outcomes is scrutinized and the balance of values underlying the policy decision to elim

295 We demonstrate that a fine balance of VEGF and angiopoietin signalling is required

296 components is typically governed by a subtle balance of weak intermolecular forces that makes structu

297 B network, which is the result of a delicate balance of weak vdW forces, causing, e.g., a pronounced

298 ucture of molecular crystals is defined by a balance of weaker intermolecular forces, and small chang

299 mine human impacts on the net greenhouse gas balance of wetlands at the global scale.

300 es a spatiotemporal function to regulate the balance of Wnt signaling and cellular heterogeneity duri