ライフサイエンスコーパス: balancer

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1 ake them suitable as an appropriately marked balancer.

2 ertions that are useful as dominant, genetic balancers and a set of lacO insertions to track genome p

3 Balancers are particularly useful in mutagenesis screens

4 s on the basis of their position relative to balancer breakpoints, leading to a broad distribution of

5 However, the use of a balancer chromosome (where a phenotypically marked segme

6 The inversion functions as a balancer chromosome because it can be used to maintain a

7 Embryos homozygous for the TM3 balancer chromosome lack neural HRP-epitope expression.

8 Here we describe the engineering of a mouse balancer chromosome with the Cre-loxP recombination syst

9 recessive ENU mutagenesis screen that uses a balancer chromosome, inversion chromosome 11.

10 through males and made homozygous by using a balancer chromosome, most of the resulting stocks develo

11 y in descendants of a structurally identical balancer chromosome, we sequenced a panel of laboratory

12 ailable fly lines and on the widely used TM3 balancer chromosome.

13 es are sheltered from natural selection by a balancer chromosome.

14 mutation accumulation experiments involving balancer chromosomes (set I) or inbred lines (set II).

15 clonal mode for the laboratory evolution of balancer chromosomes and have implications for how balan

16 Balancer chromosomes are genetic reagents that are used

17 Despite their utility, balancer chromosomes are rarely used in mice because the

18 Initially identified in the fruitfly, balancer chromosomes are valuable genetic tools that all

19 Mouse balancer chromosomes can be engineered using Cre-loxP te

20 nation system, we have constructed two mouse balancer chromosomes carrying 8- and 30-cM inversions be

21 osomes were maintained as heterozygotes with balancer chromosomes for >100 generations before screeni

22 te their widespread use, the organization of balancer chromosomes has not been characterized at the m

23 degree of sequence variation among copies of balancer chromosomes is unknown.

24 er chromosomes and have implications for how balancer chromosomes should be used in the design and in

25 Multiply inverted balancer chromosomes that suppress exchange with their h

26 ags both rearrangements, which enables these balancer chromosomes to be visibly tracked in mouse stoc

27 Our study has implications for the use of balancer chromosomes to maintain mutant lines and provid

28 propriately marked inversions can be used as balancer chromosomes to recover and maintain mutations i

29 tion suppression are an essential feature of balancer chromosomes.

30 nal, perhaps due to selective improvement of balancer chromosomes.

31 ed, by competing them against two different "balancer" chromosomes.

32 chromosome 3 lines were estimated using the balancer equilibrium technique.

33 containing the most widely used X chromosome balancer, First Multiple 7 (FM7).

34 making this modified In(15)21Rk useful as a balancer for proximal mouse chromosome 15.

35 ssive, lethal inversion Rump White (Rw) as a balancer in a three-generation breeding scheme to identi

36 play an important physiological role as a pH balancer in the maintenance of H(+) homeostasis in C. el

37 For any inversion to be effective as a balancer, it should exhibit both dominant and recessive

38 ancers to the previously reported Trp53-Wnt3 balancer, most of mouse chromosome 11 is now available i

39 Balancer mutagenesis screens will provide a systematic f

40 where TTP, in alliance with TRAF2, acts as a balancer of JNK-mediated cell survival versus death.

41 the Ly-6 superfamily have been implicated as balancers of activity and survival in the adult nervous

42 We report new w- fluorescent balancers scorable from stage 13 through adulthood that

43 t of mouse chromosome 11 is now available in balancer stocks.

44 With the addition of these balancers to the previously reported Trp53-Wnt3 balancer

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