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1 s of adjacent subunits and an internal alpha-barrel.
2 an open cavity of the C-terminal FBXO31 beta-barrel.
3 bilayer and assemble into a 168-strand beta-barrel.
4 and from the reactions that occur inside the barrel.
5 closed pocket at the centre of the lipocalin barrel.
6 it is an 18-stranded, not 16-stranded, beta-barrel.
7 es that yield an 88-strand pore-forming beta-barrel.
8 extracellular loops within the forming beta-barrel.
9 lular loop, to the lumen of the forming beta-barrel.
10 , with the ligands paneling the sides of the barrels.
11 ic structures resembling cylindrins and beta-barrels.
12 d by a major capsid protein bearing two beta-barrels.
13 ortex, but did not affect the segregation of barrels.
14 fruity characteristics in vinegars from wood barrels.
15 ptal area, the cell-sparse region separating barrels.
16 cing residues observed in transmembrane beta-barrels.
17 te, eventually innervating non-corresponding barrels.
18 different countries matured in the same oak barrels.
19 ains and C-terminal membrane-integrated beta-barrels.
20 a home to oil sands deposits of 1.7 trillion barrels.
21 (betaalpha)8 triosephosphate isomerase (TIM) barrel, a canonical [4Fe-4S] cluster binds SAM in close
23 ) the surprisingly pervasive double-Psi beta-barrel active-site configuration among different nucleic
24 analysis revealed that freshly-distilled and barrel-aged spirits were differentiated by their megasti
26 e proteins are composed of a C-terminal beta-barrel and a different number of N-terminal POTRA domain
28 lex) mediates subsequent folding of the beta-barrel and its integration into the target membrane.
29 mA is present, indicating that both the beta-barrel and polypeptide transport-associated (POTRA) doma
32 operativity and stability of the folded beta-barrel and that the thermodynamic contributions of the l
33 pendent asymmetric distortions of the VDAC-1 barrel and the displacement of particular charged amino
34 , suggesting that lateral gating of the BamA barrel and/or hybrid barrel formation is not required, a
37 263, I299, and F387) were located in the TIM barrel around the active site in domain A, and two resid
38 fic structure with characteristics of a beta-barrel arrangement that we named beta-barrel pore-formin
39 ribe the motions of the residues of the beta-barrel as a collective rocking of low amplitude and of h
41 t are believed to be less important for beta-barrel assembly in vitro Here, we experimentally measure
42 beta-signal motif required for assisted beta-barrel assembly in vivo but are believed to be less impo
44 ponents interact with the two essential beta-barrel assembly machine (Bam) components, BamA and BamD.
45 alton five-component complex called the beta-barrel assembly machinery (BAM) complex has been implica
48 livery by periplasmic chaperones to the beta-barrel assembly machinery (BAM), which catalyzes OMP ins
51 dditionally, the effective rate for the beta-barrel assembly machinery complex necessary for physiolo
54 nd provide mechanistic insight into the beta-barrel assembly pathway that enables the rapid deploymen
55 the beta-signal motif are vital for in vitro barrel assembly, because they exhibit a side chain-speci
56 trands, and the loops extending out the beta-barrel at both N-terminus and C-terminus, which is disti
57 esel to be 1.14 (80% CI, 0.67-2.15) and 1.22 barrel/barrel (80% CI, 0.71-2.29), respectively, 13% of
61 ocyte processes are structurally confined by barrel boundaries in the mouse, by the border of primary
62 y adopt beta-barrel structures and that beta-barrels can be formed by folding an out-of-register beta
63 glucosyl-1,6-deoxynojirimycin revealed a TIM barrel catalytic domain that contains a deep substrate-b
64 The nonameric assembly reveals a long beta-barrel channel spanning the length of the complex that,
66 ioning for three structurally different beta-barrel channels: voltage-dependent anion channel from ou
67 enance of projection topology from different barrel columns in the BC, albeit with target-specific pr
68 and a P1 domain, which forms a squashed beta-barrel consisting of six antiparallel beta-strands simil
71 on is that between L5B neurons in the rodent barrel cortex (BC) and the posterior medial nucleus of t
74 imaging to assess tactile defensiveness and barrel cortex activity in young and adult Fmr1 knock-out
76 nal, bilateral whisker representation in the barrel cortex and activation of distinct cortical loci f
77 ates of the connectivity of layer 4 (L4) rat barrel cortex and numerical simulations of this circuit
79 his theory is supported by simulations of L4 barrel cortex during spontaneous and stimulus-evoked con
81 dissimilarity suggests that some aspects of barrel cortex function may not generalize to tactile pro
82 t all three major interneuron classes in the barrel cortex integrate both feedforward and feedback in
84 vivo two-photon calcium imaging of layer 2/3 barrel cortex neurons expressing GCaMP6s, we found no di
85 tion processing in adapting and non-adapting barrel cortex neurons, and that eventual deficits in inh
86 e sensory evoked population responses in the barrel cortex of aged transgenic (Tg) mice and of age-ma
87 Here, we show that pyramidal neurons in the barrel cortex of BC1 knock out (KO) mice display larger
88 rease GABAAreceptor-mediated response in the barrel cortex of mice with compromised Met signaling.
90 Here, we show that in the whisker-related barrel cortex of neonatal rats, spontaneous whisker move
91 Here, we show that, in the whisker-related barrel cortex of neonatal rats, spontaneous whisker move
93 structural and functional impairments in the barrel cortex of the Bird mouse line, a popular animal m
94 e spike frequency adaptation - split layer 5 barrel cortex pyramidal neurons into two clusters: one o
96 ion on gene expression in the adult male rat barrel cortex were investigated using RNA sequencing.
97 n on gene expression in the adult female rat barrel cortex were investigated using RNA sequencing.
98 r (L) 5 pyramidal neurons (PNs) in the mouse barrel cortex, and such spine loss closely associates wi
99 t reorganization of synaptic circuits in the barrel cortex, as well as diminished spatial and associa
101 tone on whisker-evoked NVC responses in rat barrel cortex, measured by cerebral blood flow (CBF) and
102 microscopy (EM) analysis, performed in mouse barrel cortex, showed that the proposed method has low f
104 nctionally comparable to changes in the male barrel cortex, where changes in genes related to morphol
109 U.S. pipelines (capacity greater than 100000 barrels/day) to estimate the variability of GHG emission
110 dependent protein changes include asymmetric barrel distortion, its interaction with the membrane, an
111 e demonstrate that cross-linking of the BamA barrel does not affect tOmpA folding kinetics in 1,2-dim
112 d archaellin monomer has two domains, a beta-barrel domain and a long, mildly kinked alpha-helix tail
113 al subunits that together form a single beta-barrel domain and an extracellular coiled-coil ("passeng
114 ted to form between the most C-terminal beta-barrel domain and the catalytic core domain of tTG.
115 es the beta-strands within the (beta/alpha)8-barrel domain and the linked active site loops that are
117 By mutating conserved residues in the beta-barrel domain of this protein, we generated three assemb
118 uter membrane proteins (OMPs) contain a beta barrel domain that serves as a membrane anchor, but the
119 This activity is located in the BamA beta-barrel domain, but is greater when full-length BamA is p
120 rane beta-barrels that can also identify the barrel domain, predict the topology and identify the ori
121 etween the first and last strand of the TamA barrel domain, providing the first experimental evidence
122 ng of an N-terminal "RxxxR" motif and a beta-barrel domain, represents a prototype c-di-GMP receptor.
127 minal extension, methyltransferase, and beta-barrel domains is stabilized by the dimerization arm of
128 h DNA must travel, such as the alpha-helical barrel domains of P22 portal proteins and T7 proteins th
129 ses the conserved methyltransferase and beta-barrel domains, an N-terminal extension, and a dimerizat
135 phobicity scale using the transmembrane beta-barrel Escherichia coli OmpLA as a scaffold protein.
138 ucture as primary forces in defining the TIM barrel fitness landscape and suggest that fitness landsc
139 DddY catalytic domain adopts a typical beta-barrel fold and contains two conserved cupin motifs.
143 Viperin contains a partial (betaalpha)6-barrel fold with a disordered N-terminal extension (resi
144 cture, VP24 consists of a nine-stranded beta-barrel fold with mostly antiparallel beta-strands, and t
145 in, which adopts the typical jelly-roll beta-barrel fold, and a P1 domain, which forms a squashed bet
146 xpectedly, the structures reveal a truncated barrel fold, wherein binding of large peptide substrates
150 model consistent with these findings is that barrel folding by the Bam complex begins in the periplas
152 dues at the C terminus of transmembrane beta-barrels form the beta-signal motif required for assisted
153 eral gating of the BamA barrel and/or hybrid barrel formation is not required, at least for the assem
154 he fabrication of monodisperse transmembrane barrels formed from short synthetic peptides has not bee
155 ystal structure of UvsY in four similar open-barrel heptameric assemblies and provide structural and
156 velop into discrete, concentrated patches in barrel hollows, and the complexity of the dendritic bran
157 pecific neural modules called barreloids and barrels in the contralateral thalamus and cortex represe
159 OEP40 protein forms a high conductance beta-barrel ion channel with subconductant states in planar l
161 barreloids with their corresponding cortical barrels is critical for processing of vibrissal sensory
163 dues localized to the ends of the heptameric barrel-like CP structure that occlude substrate entry po
167 philin-1 interacted directly with the RuvbL1 barrel-like structure near the opening of the central ch
169 Super-resolution imaging of Nup188 shows two barrel-like structures with dimensions and organization
172 n a closed state that prevents access to the barrel lumen, which indicates substrate OMPs may not be
173 while a solid carbon electrode in the other barrel measures the local concentration and flux of the
174 CSE genes and associated enzyme activity in barrel medic (Medicago truncatula, dicot, Leguminosae),
175 channel-1 (VDAC1) is a highly regulated beta-barrel membrane protein that mediates transport of ions
176 ic resonance spectra for both VDAC-1, a beta-barrel membrane protein, and the G-protein-coupled recep
177 is applicable to both alpha-helical and beta-barrel membrane proteins of diverse architectures with o
178 ter membrane channels known to date are beta-barrel membrane proteins, including the abundant voltage
180 ter strands, the promoter-guided assembly of barrels modified with 12 left- or right-handed tethers i
182 strate-binding domain consisting of two beta-barrel motifs, whereas cyclin D1 binds to FBXO31 by tuck
183 e the efficacy of this approach using a beta-barrel MP, outer membrane protein F (OmpF), in short-cha
184 nvestigated the dendritic differentiation of barrel neurons and individual thalamocortical axon (TCA)
185 e with respect to the integral membrane beta-barrel of BamA to induce movement of the beta-strands of
188 24% reductions in the CO2 emissions on a per barrel of crude oil processed) can be achieved in a medi
189 The approach is applied to the dynamic beta-barrel of SOD1, associated with pathologic aggregation i
191 arginine residue near the middle of the beta barrel of the Escherichia coli OMPs OmpLA and EspP creat
194 ) accident released an estimated 4.1 million barrels of oil and 10(10) mol of natural gas into the Gu
195 il and bitumen deposits amount to 9 trillion barrels of oil distributed in over 280 basins around the
196 n oil spill released approximately 4 million barrels of oil into the GOM, with severe ecosystem and e
197 spill resulted in the release of millions of barrels of oil into the Gulf of Mexico, and some marsh s
198 studies reveal rapid depletion of many beta-barrel OM proteins from JB-95-treated E. coli, consisten
199 ugh interactions of JB-95 with selected beta-barrel OM proteins, including BamA and LptD as shown by
200 a foggy environment, water drops with either barrel or clam-shell shapes are capable of self-running
202 cies that possess whiskers lack the modular "barrel" organization found in the primary somatosensory
205 mplex responsible for the biogenesis of beta-barrel outer membrane proteins (OMPs) in Gram-negative b
206 s such as the tip of a glass pipet, a double-barrel pipet, and a freestanding silicon nitride membran
207 onomeric subunit structure leading to a beta-barrel pore approximately 10 nm long and 1.6-2.5 nm wide
208 s of VDAC proteins show a wide beta-stranded barrel pore, with its N-terminal alpha-helix (N-alpha) b
209 a beta-barrel arrangement that we named beta-barrel pore-forming Abeta42 oligomers (betaPFOsAbeta42).
212 rotein PelB with a predicted C-terminal beta-barrel porin localizes to the outer membrane, and propos
213 rotein translocases drive the import of beta-barrel precursor proteins into the mitochondrial outer m
215 f the filamentous hemagglutinin adhesin beta-barrel protein transporter solubilized by n-Octyl beta-D
216 nd structure were explored using a model TIM barrel protein, indole-3-glycerol phosphate synthase (IG
217 wed the folding of the Escherichia coli beta-barrel protein, LptD, with its lipoprotein plug, LptE.
218 rization of hydration dynamics around a beta-barrel protein, rat liver fatty acid-binding protein (rL
220 transmembrane region of outer membrane beta-barrel proteins (OMPs) by combining an empirical energy
221 genesis of mitochondrial outer membrane beta-barrel proteins (SAM/TOB) complex and controls the shape
223 ng antibiotics that specifically target beta-barrel proteins and the integrity of the Gram-negative O
224 o obtaining evidence that at least some beta-barrel proteins begin to fold before they interact with
227 e Bam complex promotes the insertion of beta-barrel proteins into the bacterial outer membrane, but i
229 M promotes the folding and insertion of beta-barrel proteins into the outer membrane via a poorly und
230 rerequisite for membrane integration of beta-barrel proteins is burial of the extracellular loops wit
236 asing the pH of the solution destabilize the barrel region, the central part of vault particles, and
237 ops (linking the C and D strands of the beta-barrel), replacing the depression known as the canyon, f
238 that most wild-type neurons were located in barrel rings encircling thalamocortical axon (TCA) clust
239 nylbenzene core, as pivotal moieties for the barrel-rosette ion channel formation, and the activity o
240 A theoretical model of the supramolecular barrel-rosette, favored by a network of intermolecular h
242 s into UpaG assembly, we show that UpaG beta-barrel segments fold into a trimeric structure in the pe
249 cal activity across a range of species; from barrel-specific blood flow in the rodent somatosensory c
251 lecular dynamics simulation of the archetype barrel-stave alamethicin (alm) pore in a 1,2-dioleoyl-sn
252 ween molecular models of AMP actions such as barrel-stave pore formation, toroidal pore formation, an
253 ion was initialized with 20 peptides in four barrel-stave pores in a fully hydrated 1-palmitoyl-2-ole
256 eaved to form VP2 and VP4, so the 'VP2' beta-barrel structure is complemented with a unique extended
257 l decoherence because of the protective beta-barrel structure that encapsulates the fluorophore in th
258 rel structure, whereas the latter displays a barrel structure with a distorted square orthobicupola g
259 lpha/beta)8 triose-phosphate isomerase (TIM) barrel structure with a highly conserved active site.
260 alysis indicated that Der p 13 adopts a beta-barrel structure with a predominately apolar pocket repr
261 ntegral transmembrane proteins assume a beta-barrel structure, and their assembly is catalyzed by the
263 n to autofluorescent FPs is their tight beta-barrel structure, which provides the rigidity and chemic
265 oligomers of these fragments may adopt beta-barrel structures and that beta-barrels can be formed by
268 nding peptides on opposite sides of its beta-barrel supports the fabrication of protein-capped ZnS:Mn
271 aximum SDF value of 30.36%, were as follows: barrel temperature, 129 degrees C; feed moisture, 15%; a
272 cessed in a single-screw extruder at various barrel temperatures (X1; 115-135 degrees C), feed moistu
274 show that the pore is most probably a helix barrel that contains eight D4 peptides arranged in paral
275 ular structures: a 60-stranded vertical beta-barrel that forms a large inner channel encircled by two
276 tDIR6 as an eight-stranded antiparallel beta-barrel that forms a trimer with spatially well-separated
277 ogy prediction method for transmembrane beta-barrels that can also identify the barrel domain, predic
279 h activity flows sequentially from visual to barrel then to hindlimb somatosensory; the second princi
282 ructural motifs range from multi-beta-strand barrels, to beta-sheet cups and baskets covered by alpha
283 r these compounds were observed depending on barrel toasting, wine matrix and their interactions.
285 residues on the interior of the nascent beta-barrel wall with residues in one of the extracellular lo
286 vated neuronal network within the responsive barrel was unchanged, as characterized by c-Fos upregula
287 s as a cheaper alternative to expensive wood barrels was recently permitted in Europe, which led to a
289 different containers (glass, oak and cherry barrels) were determined by gas chromatography-olfactome
290 etely de novo and thermostable alpha-helical barrel, which comprises seven helices arranged around an
291 revealed a domain-like insertion into a TIM-barrel, which might serve as a flexible lid for the acti
292 the targeted synthesis of pentagonal Pt10L5 barrels, which are formed in nearly quantitative yields.
299 modular design for PNTs using alpha-helical barrels with tunable internal cavities as building block
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