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1 ceive dense cholinergic projections from the basal forebrain.
2 se routes depending on their location in the basal forebrain.
3 he location of the cholinergic neuron in the basal forebrain.
4 on and largely through nicotinic inputs from basal forebrain.
5 stsynaptic currents and elevated dopamine in basal forebrain.
6 e hippocampus, cerebral cortex, amygdala and basal forebrain.
7 rior neural plate that will give rise to the basal forebrain.
8 mainly produce noncholinergic neurons in the basal forebrain.
9 n the striatum and projection neurons in the basal forebrain.
10 ave widespread projections, including to the basal forebrain.
11 oject to the cerebral cortex and cholinergic basal forebrain.
12 rtex over the basal ganglia and decreased in basal forebrain.
13 of the cholinergic phenotype by BMP9 in the basal forebrain.
14 n, receives cholinergic innervation from the basal forebrain.
15 han their counterparts in other parts of the basal forebrain.
16 ctivate (i.e., induce Fos expression in) the basal forebrain.
17 NR3C1 in the cerebral cortex and SRF in the basal forebrain.
18 nstem pedunculopontine tegmental nucleus and basal forebrain.
19 ssessment, and volumetric measurement of the basal forebrain.
20 receive extensive cholinergic input from the basal forebrain.
21 t), tuberomammillary nuclei (histamine; HA), basal forebrain (acetylcholine; ACh), dorsal raphe (sero
23 This facilitation was reduced by half during basal forebrain activation due to differential response
26 ewise, stimulation of MLR projections to the basal forebrain also enhanced cortical responses, sugges
27 quires local release of acetylcholine in the basal forebrain and activation of cortically projecting,
29 e predominant VGLUT isoform expressed in the basal forebrain and brainstem, including PVH-projecting
31 ns in the brain norepinephrine system in the basal forebrain and cingulate cortex may mediate allosta
32 and rdAcbSh would be but one of many in the basal forebrain and conclude by reiterating the longstan
34 uced depletion of cholinergic neurons in the basal forebrain and decreased innervation of the hippoca
35 ropin-releasing hormone (GnRH) reside in the basal forebrain and drive reproductive function in mamma
36 e examined whether longitudinal decreases in basal forebrain and entorhinal cortex grey matter volume
38 neuronal loss in the cortex, hippocampus and basal forebrain and gliosis and microgliosis in the hipp
39 between both discrete anatomic regions (e.g. basal forebrain and hippocampus) and cell types (neurona
42 ivation, that PB projections to the preoptic-basal forebrain and lateral hypothalamus, but not to the
43 telencephalic structures are produced in the basal forebrain and migrate to their final destinations
44 1 receptor electroporation into cells of the basal forebrain and pharmacological activation of the re
45 ceive projections from the claustrum and the basal forebrain and project to the caudate, the basis po
46 neurons, the first of which projects to the basal forebrain and regulates EEG components of REM slee
52 infusions of 192 IgG-saporin (SAP) into the basal forebrain and/or 6-hydroxydopamine (6-OHDA) into t
53 vast majority of cholinergic neurons in the basal forebrain, and appears to be an important regulato
54 n to receive numerous afferents from cortex, basal forebrain, and brainstem and the SNc is widely per
55 ateral thalamus, basal ganglia, hippocampus, basal forebrain, and brainstem) was assessed across (1)
56 us receives cholinergic projections from the basal forebrain, and functional studies have suggested t
57 eased size in FXS, such as the orbital gyri, basal forebrain, and thalamus, suggests delayed or other
59 number of structures within the rostromedial basal forebrain are critical for affiliative behaviors a
62 ls of the alpha1- adrenergic receptor in the basal forebrain as well as alpha2- and beta1-adrenergic
63 ally connected with the olfactory system and basal forebrain, as well as with the chemosensory and ba
64 ergic inputs to the auditory cortex from the basal forebrain (BF) are important to auditory processin
66 lysis, we report that optical stimulation of basal forebrain (BF) cholinergic neurons in mice increas
67 o sleep is determined by the activity of the basal forebrain (BF) cholinergic neurons, which release
72 aneously with electrical stimulations of the basal forebrain (BF) in urethane-anesthetized rats, we i
74 Pharmacological studies had implicated the basal forebrain (BF) inducible nitric oxide (NO) synthas
81 vivo whether selective activation of either basal forebrain (BF) or cholinergic innervation is suffi
85 ding the control of sleep-wake states by the basal forebrain (BF) poses a challenge due to the interm
86 inic receptors by cholinergic axons from the basal forebrain (BF) significantly impacts cortical func
88 y a functional GABAergic projection from the basal forebrain (BF) to the lateral habenula (lHb) that
89 ctional connections between the amygdala and basal forebrain (BF), a brain area long implicated in at
90 neurons excite wake-promoting neurons in the basal forebrain (BF), and a reciprocal projection from t
91 al correlate of motivational salience in the basal forebrain (BF), defined independently of RT, is co
92 ily innervate the cholinergic neurons in the basal forebrain (BF), histamine neurons in the tuberomam
97 nosine-sensitive biosensors in slices of the basal forebrain (BFB) to study both depolarization-evoke
98 ficial effects on cholinergic neurons in the basal forebrain but that these effects are both age and
100 leep and AD levels increase with wake in the basal forebrain, but surprisingly it still remains untes
101 vivo inhibition of GABAergic neurons in the basal forebrain by targeted expression of designer recep
103 nimal models, development of the cholinergic basal forebrain (cBF) is selectively vulnerable to adver
104 including early degeneration of cholinergic basal forebrain (CBF) neurons and impairments in functio
105 hin receptor (p75(NTR)) in adult cholinergic basal forebrain (cBF) neurons is unclear due to conflict
109 eoptic area, and diagonal band nuclei of the basal forebrain; central, medial, cortical, and basal nu
112 addition to innervating the cerebral cortex, basal forebrain cholinergic (BFc) neurons send a dense p
113 ew discusses recent advances in the roles of basal forebrain cholinergic and noncholinergic neurons i
114 gic medications and prior dementia, in which basal forebrain cholinergic degeneration is a prominent
115 effects of a GPR30 agonist and antagonist on basal forebrain cholinergic function and cognitive perfo
118 neuritic dystrophy and complete reversal of basal forebrain cholinergic neurite degeneration relativ
120 heimer's phenotype and into the mechanism of basal forebrain cholinergic neuronal selective vulnerabi
121 acquisition of the cholinergic phenotype in basal forebrain cholinergic neurons (BFCN) during develo
122 etylcholine (ACh) synthesis and release from basal forebrain cholinergic neurons (BFCN) innervating t
123 thesis of acetylcholine and its release from basal forebrain cholinergic neurons (BFCN) that innervat
128 ere investigated in PC12 cells, cultured rat basal forebrain cholinergic neurons (BFCNs), and BFCNs f
130 immunotoxic lesion that destroyed 40-50% of basal forebrain cholinergic neurons and later, after ext
131 t there is a topographic mapping between the basal forebrain cholinergic neurons and their axonal pro
132 unctional, heteromeric alpha7beta2-nAChRs on basal forebrain cholinergic neurons and their high sensi
136 he cortex through optogenetic stimulation of basal forebrain cholinergic neurons decreases the depend
137 umulation is a relatively selective trait of basal forebrain cholinergic neurons early in adult life,
138 Defining the full morphologies of individual basal forebrain cholinergic neurons has, until now, been
139 ular mechanisms are not well understood, the basal forebrain cholinergic neurons have been implicated
140 hin receptor expressed almost exclusively in basal forebrain cholinergic neurons in adult brain.
141 otential contributors to the degeneration of basal forebrain cholinergic neurons in Alzheimer's disea
142 These results underscore the causal role of basal forebrain cholinergic neurons in fast, bidirection
143 selective vulnerability of the magnocellular basal forebrain cholinergic neurons in neurodegenerative
144 fibrillogenic 42-amino acid isoform, within basal forebrain cholinergic neurons in normal young, nor
145 amygdaloid area (cSLR/AAA) differ from other basal forebrain cholinergic neurons in several morpholog
146 esponsible for the phenotypic maintenance of basal forebrain cholinergic neurons in the mature and fu
149 pressed channelrhodopsin or halorhodopsin in basal forebrain cholinergic neurons of mice with optic f
153 to the age-related neurodegeneration of the basal forebrain cholinergic neurons that project to the
154 we found that dynorphin-A directly inhibits basal forebrain cholinergic neurons via kappa-opioid rec
156 long been known that orexin-A and -B excite basal forebrain cholinergic neurons, but orexin-producin
157 use NGF is a crucial neurotrophic factor for basal forebrain cholinergic neurons, defining the mechan
159 in mediating direct effects of estradiol on basal forebrain cholinergic neurons, with corresponding
165 image warping and a cytoarchitectonic map of basal forebrain cholinergic nuclei to a large cross-sect
167 The central nucleus (CN) of the amygdala and basal forebrain cholinergic projections to the posterior
171 e results are consistent with a role for the basal forebrain cholinergic system in dynamically regula
172 -p75-sap) to induce selective lesions of the basal forebrain cholinergic system in mice, mimicking ea
174 is study, we examine the hypothesis that the basal forebrain cholinergic system is required for elici
176 ious views on the cognitive functions of the basal forebrain cholinergic system often suggested that
178 b of the diagonal band of Broca (HDB) of the basal forebrain complex, which are areas highly implicat
180 egion connecting the olfactory bulb with the basal forebrain, contains several neural areas that have
181 ured along a rostral to caudal extent in the basal forebrain correlated with a ventral to dorsal and
182 electroencephalogram (EEG) are sensitive to basal forebrain corticopetal cholinergic modulation.
183 ral systems related to sleep and wake in the basal forebrain, diencephalon, midbrain, and pons of the
184 trol and regulation of sleep and wake in the basal forebrain, diencephalon, midbrain, and pons of the
185 urons in the rostral and caudal parts of the basal forebrain differentially innervate the superficial
189 nd delta activity by adenosine infusion into basal forebrain during the normally active dark period a
191 development and function, the development of basal forebrain excitatory and inhibitory neurons is cri
193 We then retrogradely labeled inputs to the basal forebrain from the upper brainstem, and found a su
195 p75 is also required for the maintenance of basal forebrain GABAergic neurons in vivo, demonstrating
198 e developed cholinergic neuronal loss in the basal forebrain, GABAergic neuronal loss in the cortex,
199 relationship between realignment to PHC and basal forebrain gray matter volume despite this region d
201 e lines to target specific cell types in the basal forebrain have led to a renaissance in this field
202 ex above the diencephalon], caudate-putamen, basal forebrain, hypothalamus, hippocampus, thalamus, te
203 rmore, disruption of orexin signaling in the basal forebrain impairs the cholinergic response to an a
205 organ (VNO) in the nasal compartment to the basal forebrain in mice, beginning on embryonic day 11 (
206 nit of the AChR (Chrna2) is expressed in the basal forebrain, in the septum, and in some amygdalar nu
208 we found that electrical stimulation of the basal forebrain increased cortical choline transporter (
209 distinct neuronal populations in the mature basal forebrain: inhibitory MSNs in the striatum and fun
210 inergic [acetylcholine (ACh)] axons from the basal forebrain innervate olfactory bulb glomeruli, the
212 demonstrates that optogenetic activation of basal forebrain input is sufficient to train reward timi
218 ocrine cells in the rostral hypothalamus and basal forebrain is the key regulator of vertebrate repro
219 tructures critical to arousal, including the basal forebrain, lateral hypothalamus, midline thalamus,
221 rtebrate basal ganglia derive from embryonic basal forebrain lineages that are specified by an evolut
224 ific atrophy in the midbrain, basal ganglia, basal forebrain, medial temporal lobe, and discrete cort
226 g protein)], a homeodomain gene required for basal forebrain morphogenesis, remains expressed in the
227 mework for integration of information within basal forebrain networks and for the modulation of corti
228 arising from cortical, extended amygdala and basal forebrain networks to ultimately generate a highly
230 holinergic and GABAergic neurons in neonatal basal forebrain neuron cultures from the region of the m
232 work demonstrates assembly formation in rat basal forebrain neuronal populations during a selective
235 ence demonstrated that virtually all ChAT-ir basal forebrain neurons were also p75(NTR) -positive.
236 nced by temporal coordination among coactive basal forebrain neurons, or the emergence of "cell assem
237 nt modulation of excitability in cholinergic basal forebrain neurons, our findings implicate PrP(C) r
239 show that Tof/Fezl is required to establish basal forebrain ngn1-expressing DA progenitor domains.
240 nduces the cholinergic phenotype in a set of basal forebrain non-cholinergic neurons or precursor cel
241 e nucleus basalis magnocellularis (NBM), the basal forebrain nuclei that provide the majority of neoc
242 corpus callosum, internal capsule, thalamus, basal forebrain, occipital, parietal and temporal lobes,
243 r of endo-lysosomal membrane rupture) in the basal forebrain of DLBD, but not in age-matched controls
244 demonstrate that cholinergic axons from the basal forebrain of mice excite a specific subset of cort
245 tubercle, a trilaminar structure within the basal forebrain, of anesthetized mice revealed that olfa
249 P neurotransmission within components of the basal forebrain particularly the nucleus accumbens and v
251 mulation of the substantia innominata of the basal forebrain phase shifts the circadian clock in a ma
253 report that cholinergic neurons of the mouse basal forebrain potently influence food intake and body
254 l and ventral torus semicircularis); and (4) basal forebrain, preoptic area, and hypothalamic nuclei.
256 egions; 2) the topographical organization of basal forebrain-projecting locus coeruleus neurons; and
262 nization of noradrenergic efferents to these basal forebrain regions by using combined immunohistoche
265 , we found that cholinergic projections from basal forebrain regulate OB output by increasing the spi
266 cate neurotransmitter co-transmission in the basal forebrain regulation of this inhibitory olfactory
267 in the cerebellum, hippocampus, thalamus and basal forebrain seem to constitute a separate phenomenon
268 dopsin to stimulate GABAergic axons from the basal forebrain selectively and show that this stimulati
269 he firing rates, but has no effect on either basal forebrain serotonin levels or conflict-anxiety mea
270 n of the subgenual anterior cingulate cortex/basal forebrain (sgACC) drives learning only when we are
271 of the cerebellum, hippocampus, thalamus and basal forebrain still remained associated with delirium
273 ility to elevate extracellular ACh following basal forebrain stimulation, in parallel with a diminish
274 ites and axons of cholinergic neurons in the basal forebrain, striatum and pedunculopontine nuclei, i
275 ound in discrete neuronal systems, including basal forebrain structures, anterior nuclear group of th
276 hat a phylogenetically conserved ensemble of basal forebrain structures, especially the septohypothal
277 enular neurons primarily received input from basal forebrain structures, the bed nucleus of stria ter
278 a prefrontal cortex, that reach the specific basal forebrain subgroups from which they receive affere
282 emely dense cholinergic innervation from the basal forebrain that is critical for memory consolidatio
283 s a significant source of projections to the basal forebrain, the phenotype(s) of these inputs and th
284 ally projecting neurons of the magnocellular basal forebrain; thus, there is a circuit substrate thro
286 leus and precoeruleus region, relayed by the basal forebrain to the cerebral cortex, may be critical
288 s served by cholinergic projections from the basal forebrain to the frontal cortex and supported by v
289 we examined how cholinergic projections from basal forebrain to the olfactory bulb (OB) modulate outp
290 inputs, like the cholinergic inputs from the basal forebrain, to determine threshold set points for f
291 to hypothesize that the rdAcbSh represents a basal forebrain transition area, in the sense that it is
292 ity of cortex with both central thalamus and basal forebrain underlies decreasing levels of conscious
293 ognitively normal to AD, we demonstrate that basal forebrain volume predicts longitudinal entorhinal
294 and basal ganglia nuclei, respectively; the basal forebrain was atrophied in proportion to patients'
295 umber and size of cholinergic neurons in the basal forebrain was examined in surgically menopausal yo
296 cortical afferents from the thalamus or the basal forebrain were more important in maintaining arous
297 are distributed in cholinergic parts of the basal forebrain, where application of orexin peptides in
298 genetic activation of cholinergic neurons in basal forebrain, which led to a mixture of mitral/tufted
299 s the dense cholinergic innervation from the basal forebrain, which terminates in both the granule ce
300 mplex of the epithalamus connects the limbic basal forebrain with numerous neuromodulatory centers in
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